Gene Symbol | MAN2B1 |
Entrez Gene ID | 282272 |
Full Name | mannosidase alpha class 2B member 1 |
Synonyms | MANB |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » MAN2B1 cDNA ORF clone
Gene Symbol | MAN2B1 |
Entrez Gene ID | 282272 |
Full Name | mannosidase alpha class 2B member 1 |
Synonyms | MANB |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_015471957.2 | XP_015327443.1 | lysosomal alpha-mannosidase isoform X1 |
XM_015471957.1 | XP_015327443.1 | lysosomal alpha-mannosidase isoform X1 |
NM_174561.2 | NP_776986.2 | lysosomal alpha-mannosidase precursor |
Pan troglodytes (chimpanzee) | MAN2B1 | XP_003316198.2 |
Arabidopsis thaliana (thale cress) | AT5G13980 | NP_196902.2 |
Bos taurus (cattle) | MAN2B1 | NP_776986.2 |
Rattus norvegicus (Norway rat) | Man2b1 | NP_955436.1 |
Mus musculus (house mouse) | Man2b1 | NP_034894.2 |
Drosophila melanogaster (fruit fly) | LM408 | NP_609408.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008584 | XP_557731.3 |
Xenopus tropicalis (tropical clawed frog) | man2b1 | NP_001072469.1 |
Homo sapiens (human) | MAN2B1 | NP_000519.2 |
LOC716173 | XP_002801133.1 | |
Canis lupus familiaris (dog) | MAN2B1 | XP_005632890.1 |
Danio rerio (zebrafish) | man2b1 | NP_001014354.1 |
Caenorhabditis elegans (roundworm) | aman-1 | NP_508811.1 |
Oryza sativa (rice) | Os11g0525600 | NP_001067993.1 |
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation.
Heikinheimo P, Helland R, Leiros HK, Leiros I, Karlsen S, Evjen G, Ravelli R, Schoehn G, Ruigrok R, Tollersrud OK, McSweeney S, Hough E
Journal of molecular biology327(3)631-44(2003 Mar)
Linkage mapping of the bovine lysosomal alpha-mannosidase (MANB) gene.
Gelhaus A, Hanotte O, Horstmann RD, Teale AJ
Animal genetics30(3)227-8(1999 Jun)
Purification of bovine lysosomal alpha-mannosidase, characterization of its gene and determination of two mutations that cause alpha-mannosidosis.
Tollersrud OK, Berg T, Healy P, Evjen G, Ramachandran U, Nilssen O
European journal of biochemistry246(2)410-9(1997 Jun)
Synteny mapping of four genes from the short arm of human chromosome 19 to bovine chromosome 7.
Gu ZX, Womack JE, Kirkpatrick BW
Cytogenetics and cell genetics79(3-4)225-7(1997)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a previously undetected mechanism of low-pH activation and a role in lysosomal transport
Title: The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation.
The following MAN2B1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAN2B1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa42461 | |
Clone ID Related Accession (Same CDS sequence) | NM_174561.2 | |
Accession Version | NM_174561.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3000bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Bos taurus(cattle) | |
Product | lysosomal alpha-mannosidase precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L31373.2. On Jun 3, 2003 this sequence version replaced NM_174561.1. ##Evidence-Data-START## Transcript exon combination :: L31373.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGTTGGTG ACGCGCGGCC TTCAGGGGTT CGCGCTGGCG GCTGCCGGGG CGCGGTAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776986.2 |
CDS | 15..3014 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174561.2 |
1 | ATGGTTGGTG ACGCGCGGCC TTCAGGGGTT CGCGCTGGCG GCTGCCGGGG CGCGGTAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa91043 | |
Clone ID Related Accession (Same CDS sequence) | XM_015471957.2 , XM_015471957.1 | |
Accession Version | XM_015471957.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2814bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | lysosomal alpha-mannosidase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037334.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_015471957.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAATG TACACCTGGT GCCTCACACA CATGATGATG TAGGCTGGCT CAAGACGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015327443.1 |
CDS | 206..3019 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015471957.2 |
1 | ATGCTGAATG TACACCTGGT GCCTCACACA CATGATGATG TAGGCTGGCT CAAGACGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa91043 | |
Clone ID Related Accession (Same CDS sequence) | XM_015471957.2 , XM_015471957.1 | |
Accession Version | XM_015471957.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2814bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | lysosomal alpha-mannosidase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104013.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAATG TACACCTGGT GCCTCACACA CATGATGATG TAGGCTGGCT CAAGACGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015327443.1 |
CDS | 167..2980 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015471957.1 |
1 | ATGCTGAATG TACACCTGGT GCCTCACACA CATGATGATG TAGGCTGGCT CAAGACGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A whole-genome assembly of the domestic cow, Bos taurus. |
The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation. |
Linkage mapping of the bovine lysosomal alpha-mannosidase (MANB) gene. |
Purification of bovine lysosomal alpha-mannosidase, characterization of its gene and determination of two mutations that cause alpha-mannosidosis. |
Synteny mapping of four genes from the short arm of human chromosome 19 to bovine chromosome 7. |