Gene Symbol | CSN1S2 |
Entrez Gene ID | 282209 |
Full Name | casein alpha-S2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
ORF » Species Summary » Bos taurus » CSN1S2 cDNA ORF clone
Gene Symbol | CSN1S2 |
Entrez Gene ID | 282209 |
Full Name | casein alpha-S2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_024993018.1 | XP_024848786.1 | alpha-S2-casein isoform X2 |
XM_015471657.1 | XP_015327143.1 | alpha-S2-casein isoform X1 |
XM_015471657.2 | XP_015327143.1 | alpha-S2-casein isoform X3 |
XM_024993017.1 | XP_024848785.1 | alpha-S2-casein isoform X1 |
NM_174528.2 | NP_776953.1 | alpha-S2-casein precursor |
Translation attenuation via 3' terminal codon usage in bovine csn1s2 is responsible for the difference in ?s2- and ?-casein profile in milk.
Kim JJ, Yu J, Bag J, Bakovic M, Cant JP
RNA biology12(3)354-67(2015)
Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovine ?S-casein.
Mizushige T, Sawashi Y, Yamada A, Kanamoto R, Ohinata K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology27(7)2911-7(2013 Jul)
The chaperone action of bovine milk ?S1- and ?S2-caseins and their associated form ?S-casein.
Treweek TM, Thorn DC, Price WE, Carver JA
Archives of biochemistry and biophysics510(1)42-52(2011 Jun)
Amyloid fibril formation by bovine milk alpha s2-casein occurs under physiological conditions yet is prevented by its natural counterpart, alpha s1-casein.
Thorn DC, Ecroyd H, Sunde M, Poon S, Carver JA
Biochemistry47(12)3926-36(2008 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Translation attenuation via 3' terminal codon usage in bovine mRNA is responsible for the difference in alpha-S2- and beta-casein profile in milk.
Title: Translation attenuation via 3' terminal codon usage in bovine csn1s2 is responsible for the difference in ?s2- and ?-casein profile in milk.
Data indicate that the pepsin-pancreatin digest of alphaS-Casein exhibited anxiolytic-like activity.
Title: Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovine ?S-casein.
Alpha-S2-casein was less effective at preventing fibril formation by modified kappa-casein, whereas alpha- and alpha-S1 casein were comparably potent inhibitors.
Title: The chaperone action of bovine milk ?S1- and ?S2-caseins and their associated form ?S-casein.
bovine milk alpha s2-casein readily forms fibrils in vitro. Upon incubation at neutral pH & 37 degrees C, spherical particles typical of alpha s2-casein rapidly converted to twisted, ribbon-like fibrils approximately 12 nm in diameter.
Title: Amyloid fibril formation by bovine milk alpha s2-casein occurs under physiological conditions yet is prevented by its natural counterpart, alpha s1-casein.
Substitution effects of paternal CSN2alpha(s1) allele versus CSN2alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not.
Title: Associations between 2 paternal casein haplotypes and milk yield traits of Swiss Fleckvieh cattle.
The following CSN1S2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSN1S2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01235 | |
Clone ID Related Accession (Same CDS sequence) | NM_174528.2 | |
Accession Version | NM_174528.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | alpha-S2-casein precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M16644.1. On Jun 3, 2003 this sequence version replaced NM_174528.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M16644.1, BC114773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145447 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776953.1 |
CDS | 57..725 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174528.2 |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa235133 | |
Clone ID Related Accession (Same CDS sequence) | XM_024993017.1 | |
Accession Version | XM_024993017.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | alpha-S2-casein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037333.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024848785.1 |
CDS | 63..731 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024993017.1 |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa235134 | |
Clone ID Related Accession (Same CDS sequence) | XM_024993018.1 | |
Accession Version | XM_024993018.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | alpha-S2-casein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037333.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024848786.1 |
CDS | 101..742 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024993018.1 |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa90943 | |
Clone ID Related Accession (Same CDS sequence) | XM_015471657.1 , XM_015471657.2 | |
Accession Version | XM_015471657.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | alpha-S2-casein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103978.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015327143.1 |
CDS | 118..759 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015471657.1 |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa90943 | |
Clone ID Related Accession (Same CDS sequence) | XM_015471657.1 , XM_015471657.2 | |
Accession Version | XM_015471657.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | alpha-S2-casein isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037333.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_015471657.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015327143.1 |
CDS | 101..742 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015471657.2 |
1 | ATGAAGTTCT TCATCTTTAC CTGCCTTTTG GCTGTTGCCC TTGCAAAGAA TACGATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Translation attenuation via 3' terminal codon usage in bovine csn1s2 is responsible for the difference in ?s2- and ?-casein profile in milk. |
Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovine ?S-casein. |
The chaperone action of bovine milk ?S1- and ?S2-caseins and their associated form ?S-casein. |
Amyloid fibril formation by bovine milk alpha s2-casein occurs under physiological conditions yet is prevented by its natural counterpart, alpha s1-casein. |