Gene Symbol | GRK3 |
Entrez Gene ID | 282136 |
Full Name | G protein-coupled receptor kinase 3 |
Synonyms | ADRBK2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » GRK3 cDNA ORF clone
Gene Symbol | GRK3 |
Entrez Gene ID | 282136 |
Full Name | G protein-coupled receptor kinase 3 |
Synonyms | ADRBK2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_024977014.1 | XP_024832782.1 | beta-adrenergic receptor kinase 2 isoform X1 |
XM_024977018.1 | XP_024832786.1 | beta-adrenergic receptor kinase 2 isoform X3 |
XM_024977016.1 | XP_024832784.1 | beta-adrenergic receptor kinase 2 isoform X2 |
XM_024977017.1 | XP_024832785.1 | beta-adrenergic receptor kinase 2 isoform X3 |
NM_174500.2 | NP_776925.1 | beta-adrenergic receptor kinase 2 |
Homo sapiens (human) | ADRBK2 | NP_005151.2 |
Caenorhabditis elegans (roundworm) | grk-2 | NP_497235.2 |
Pan troglodytes (chimpanzee) | ADRBK2 | XP_003317197.1 |
Mus musculus (house mouse) | Adrbk2 | NP_796052.2 |
Canis lupus familiaris (dog) | ADRBK2 | XP_543453.3 |
Drosophila melanogaster (fruit fly) | Gprk1 | NP_001163051.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012026 | XP_320502.4 |
Xenopus tropicalis (tropical clawed frog) | adrbk2 | XP_002932117.2 |
ADRBK2 | XP_001104308.1 | |
Bos taurus (cattle) | ADRBK2 | NP_776925.1 |
Rattus norvegicus (Norway rat) | Adrbk2 | NP_037029.1 |
Gallus gallus (chicken) | ADRBK2 | XP_415195.4 |
Danio rerio (zebrafish) | adrbk2 | NP_001128197.1 |
The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers.
Hollins B, Kuravi S, Digby GJ, Lambert NA
Cellular signalling21(6)1015-21(2009 Jun)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.
Benovic JL, Onorato JJ, Arriza JL, Stone WC, Lohse M, Jenkins NA, Gilbert DJ, Copeland NG, Caron MG, Lefkowitz RJ
The Journal of biological chemistry266(23)14939-46(1991 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Fusion proteins containing the c-terminus of GPCR kinase 3 (GRK3ct) and either the fluorescent protein cerulean or Renilla luciferase bind to venus-labeled Gbetagamma dimers, resulting in Forster or bioluminescence resonance energy transfer.
Title: The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers.
The following GRK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GRK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41490 | |
Clone ID Related Accession (Same CDS sequence) | NM_174500.2 | |
Accession Version | NM_174500.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2067bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-23 | |
Organism | Bos taurus(cattle) | |
Product | beta-adrenergic receptor kinase 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M73216.1. On Jun 3, 2003 this sequence version replaced NM_174500.1. ##Evidence-Data-START## Transcript exon combination :: M73216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145415, SAMN03145419 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGACC TGGAGGCCGT GCTGGCCGAT GTCAGCTACC TGATGGCGAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776925.1 |
CDS | 49..2115 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174500.2 |
1 | ATGGCGGACC TGGAGGCCGT GCTGGCCGAT GTCAGCTACC TGATGGCGAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa224149 | |
Clone ID Related Accession (Same CDS sequence) | XM_024977014.1 | |
Accession Version | XM_024977014.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | beta-adrenergic receptor kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037344.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGACC TGGAGGCCGT GCTGGCCGAT GTCAGCTACC TGATGGCGAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024832782.1 |
CDS | 69..2231 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024977014.1 |
1 | ATGGCGGACC TGGAGGCCGT GCTGGCCGAT GTCAGCTACC TGATGGCGAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa224150 | |
Clone ID Related Accession (Same CDS sequence) | XM_024977016.1 | |
Accession Version | XM_024977016.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | beta-adrenergic receptor kinase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037344.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGACC TGGAGGCCGT GCTGGCCGAT GTCAGCTACC TGATGGCGAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024832784.1 |
CDS | 69..2021 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024977016.1 |
1 | ATGGCGGACC TGGAGGCCGT GCTGGCCGAT GTCAGCTACC TGATGGCGAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa224151 | |
Clone ID Related Accession (Same CDS sequence) | XM_024977018.1 , XM_024977017.1 | |
Accession Version | XM_024977018.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1824bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | beta-adrenergic receptor kinase 2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037344.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGGAGC TGCTGTCGTG TTCACATCCA TTCTCAAAGC AAGCCGTAGA ACACGTACAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024832786.1 |
CDS | 153..1976 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024977018.1 |
1 | ATGAAGGAGC TGCTGTCGTG TTCACATCCA TTCTCAAAGC AAGCCGTAGA ACACGTACAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa224151 | |
Clone ID Related Accession (Same CDS sequence) | XM_024977018.1 , XM_024977017.1 | |
Accession Version | XM_024977017.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1824bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | beta-adrenergic receptor kinase 2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037344.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGGAGC TGCTGTCGTG TTCACATCCA TTCTCAAAGC AAGCCGTAGA ACACGTACAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024832785.1 |
CDS | 229..2052 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024977017.1 |
1 | ATGAAGGAGC TGCTGTCGTG TTCACATCCA TTCTCAAAGC AAGCCGTAGA ACACGTACAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family. |