PROS1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	PROS1
Entrez Gene ID	282006
Full Name	protein S
General protein information	Preferred Names protein S Names vitamin K-dependent protein S protein S (alpha)
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174438.1	NP_776863.1	vitamin K-dependent protein S precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PROS1	XP_005639500.1
Danio rerio (zebrafish)	pros1	NP_001070791.1
Pan troglodytes (chimpanzee)	PROS1	XP_516603.3
Gallus gallus (chicken)	PROS1	XP_416641.2
Xenopus tropicalis (tropical clawed frog)	pros1	NP_001119539.1
	PROS1	NP_001038191.1
Mus musculus (house mouse)	Pros1	NP_035303.1
Rattus norvegicus (Norway rat)	Pros1	NP_112348.2
Homo sapiens (human)	PROS1	NP_000304.2
Bos taurus (cattle)	PROS1	NP_776863.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Prevention of thrombosis following deep arterial injury in rats by bovine activated protein C requiring co-administration of bovine protein S.
Malm K, Dahlb?ck B, Arnljots B
Thrombosis and haemostasis90(2)227-34(2003 Aug)

Primary structure of bovine vitamin K-dependent protein S.
Dahlb?ck B, Lundwall A, Stenflo J
Proceedings of the National Academy of Sciences of the United States of America83(12)4199-203(1986 Jun)

Localization of thrombin cleavage sites in the amino-terminal region of bovine protein S.
Dahlb?ck B, Lundwall A, Stenflo J
The Journal of biological chemistry261(11)5111-5(1986 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Activated protein C(APC) combined with protein S(PS) had significant antithrombotic effect. APC combined with PS prolonged clotting time. Dependence on APC-cofactor activity of PS for expression of anticoagulant activity by APC.
Title: Prevention of thrombosis following deep arterial injury in rats by bovine activated protein C requiring co-administration of bovine protein S.

The following PROS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PROS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43932	NM_174438.1 Latest version!	Bos taurus protein S (PROS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PROS1 ( NM_174438.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776863.1 Bos taurus protein S (PROS1), mRNA.

Price & Availability↑

CloneID	OBa43932
Clone ID Related Accession (Same CDS sequence)	NM_174438.1
Accession Version	NM_174438.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2028bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Bos taurus(cattle)
Product	vitamin K-dependent protein S precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M13044.1. ##Evidence-Data-START## Transcript exon combination :: M13044.1, X12891.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END##

ATGAGGGTCC TAGGTGGGCG CACCGGGACG CTGCTGGCAT GCCTCGCCCT AGTGCTTCCC 
GTCTTGGAGG CTAACTTTTT GTCGAGGCAA CATGCTTCAC AAGTCCTGAT TAGGAGACGC 
CGTGCAAATA CATTGCTTGA AGAAACGAAA AAGGGCAATC TTGAAAGAGA ATGCATTGAA 
GAACTGTGCA ATAAAGAAGA AGCCAGGGAA ATCTTTGAAA ATAACCCGGA AACGGAATAT 
TTTTATCCAA AATATTTAGG TTGTCTTGGC TCTTTCAGAG CTGGATTATT CACTGCTGCT 
CGTCTGTCAA CTAATGCTTA CCCTGACCTG AGGAGCTGTG TCAATGCCAT TTCGGACCAG 
TGTAATCCTC TGCCATGCAA TGAAGATGGA TTTATGACCT GCAAAGATGG CCAAGCGACA 
TTCACTTGCA TTTGTAAATC AGGTTGGCAA GGAGAAAAGT GTGAATCTGA TATAAATGAA 
TGCAAAGATC CTGTAAATAT AAATGGAGGT TGCAGCCAGA TTTGTGAAAA CACACCTGGA 
AGTTACCACT GTTCCTGTAA AAATGGTTTT GTTATGCTTT CAAATAAAAA GGACTGCAAA 
GATGTGGATG AATGCGTTTT AAAGCCAAGC ATTTGTGGCA CAGCTGTGTG CAAGAACATC 
CCAGGAGACT TTGAATGTGA ATGTGCTGAA GGCTACAAAT ACAATCCCGT ATCAAAGTCT 
TGTGACGATG TGGATGAATG CGCTGAGAAC TTGTGTGCTC AACTTTGTGT CAATTACCCT 
GGAGGTTACT CTTGTTACTG TGACGGAAAG AAAGGATTCA AACTTGCCCA AGATCAGAAG 
AGTTGTGAGG CTGTTCCAGT GTGCCTTCCT TTGGACCTTG ACAAAAATTA TGAATTGCTT 
TACTTGGCAG AGCAGTTTGT AGGGGTTGTT TTGTATTTAA AATTTCGTTT GCCAGAAACT 
ACCAGATTTT CAGCTGAATT TGATTTCCGG ACATATGATT CAGAAGGTGT TATCCTGTAT 
GCAGAATCTT CTGATCACTC AGCTTGGTTC CTGATTGCGC TTCGTGAGGG AAAGATTGAA 
ATTCAGTTCA AGAATGAAAA GACAACCAAA ATGACAACTG GAGGCAAAGT TATTAATGAT 
GGTTTATGGC ATATGGTCTC TGTGGAAGAA TTAGAACAGA GTATTAGTGT AAAAATAGCT 
AAAGAAGCTG TAATGAATAT AAATAAGCCT GGAAGCCTTT TTAAGCCCAC CAATGGGTTT 
CTAGAAACCA AAGTATACTT TGCAGGAGTA CCTCGGAAAA TGGAAAATGC ACTCATTAGA 
CCGATTAACC CTCGTCTAGA TGGATGTATT CGAGGCTGGA ATTTGATGAA TCAAGGAACT 
TCAGGAGTAA AGGAAATCAT TCAAGAAAAA CAAAATAAGC ATTGTCTTGT CAATGTGGAG 
AAGGGTTCCT ACTATCCTGG TACTGGAGTT GCTCAGTTTA GCATAAATTA TAAGAATGAA 
TCCAATCCTG AGGCTTGGCA AATCAATGTG TCCTTGAATA TTCGCCCATC AGCGGGCACC 
GGTGTTATGT TGGCCTTGGT TTCCGATAAC ACAGTGCCCT TTGCCTTGTC CTTGGTGGAT 
TCCGCCACTG AAAAGCTTCA GGATATCCTG GTATCTGTTG AAAGTATGGT AATAGGTCGG 
ATAGAGGCCA TAAGTCTGTG TTCCGATCAG CAAACCTTTC TGGAAATCAG AGTCAACAGA 
AACAATTTGG AACTATCGAC TCAACTTAGA AAGGATAGCT TCCACTCTGA AGACTTTCAA 
AGACAATTTG CCATCTTGGA TGAAGCAATG AAAGGAACAG TGGTCACTTA CCTGGGTGGC 
CTTCCAGATG TTCCATTCAG TGCCACACCA GTGAATGCCT TTTATCAAGG CTGTATGGAA 
GTGAACATTA ATGGTGTACA GGTGGATTTG GATGAAGCCA TTTCTAAACA TAATGATATT 
AGAGCTCACT CGTGTCCATC AGTTTGGCAG AAGACAAAGC ATACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776863.1
CDS	36..2063
Translation	MRVLGGRTGTLLACLALVLPVLEANFLSRQHASQVLIRRRRANTLLEETKKGNLERECIEELCNKEEAREIFENNPETEYFYPKYLGCLGSFRAGLFTAARLSTNAYPDLRSCVNAISDQCNPLPCNEDGFMTCKDGQATFTCICKSGWQGEKCESDINECKDPVNINGGCSQICENTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECAENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNEKTTKMTTGGKVINDGLWHMVSVEELEQSISVKIAKEAVMNINKPGSLFKPTNGFLETKVYFAGVPRKMENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVNVEKGSYYPGTGVAQFSINYKNESNPEAWQINVSLNIRPSAGTGVMLALVSDNTVPFALSLVDSATEKLQDILVSVESMVIGRIEAISLCSDQQTFLEIRVNRNNLELSTQLRKDSFHSEDFQRQFAILDEAMKGTVVTYLGGLPDVPFSATPVNAFYQGCMEVNINGVQVDLDEAISKHNDIRAHSCPSVWQKTKHT

Target ORF information:

RefSeq Version	NM_174438.1
Organism	Bos taurus(cattle)
Definition	Bos taurus protein S (PROS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174438.1

ORF Insert Sequence:

ATGAGGGTCC TAGGTGGGCG CACCGGGACG CTGCTGGCAT GCCTCGCCCT AGTGCTTCCC 
GTCTTGGAGG CTAACTTTTT GTCGAGGCAA CATGCTTCAC AAGTCCTGAT TAGGAGACGC 
CGTGCAAATA CATTGCTTGA AGAAACGAAA AAGGGCAATC TTGAAAGAGA ATGCATTGAA 
GAACTGTGCA ATAAAGAAGA AGCCAGGGAA ATCTTTGAAA ATAACCCGGA AACGGAATAT 
TTTTATCCAA AATATTTAGG TTGTCTTGGC TCTTTCAGAG CTGGATTATT CACTGCTGCT 
CGTCTGTCAA CTAATGCTTA CCCTGACCTG AGGAGCTGTG TCAATGCCAT TTCGGACCAG 
TGTAATCCTC TGCCATGCAA TGAAGATGGA TTTATGACCT GCAAAGATGG CCAAGCGACA 
TTCACTTGCA TTTGTAAATC AGGTTGGCAA GGAGAAAAGT GTGAATCTGA TATAAATGAA 
TGCAAAGATC CTGTAAATAT AAATGGAGGT TGCAGCCAGA TTTGTGAAAA CACACCTGGA 
AGTTACCACT GTTCCTGTAA AAATGGTTTT GTTATGCTTT CAAATAAAAA GGACTGCAAA 
GATGTGGATG AATGCGTTTT AAAGCCAAGC ATTTGTGGCA CAGCTGTGTG CAAGAACATC 
CCAGGAGACT TTGAATGTGA ATGTGCTGAA GGCTACAAAT ACAATCCCGT ATCAAAGTCT 
TGTGACGATG TGGATGAATG CGCTGAGAAC TTGTGTGCTC AACTTTGTGT CAATTACCCT 
GGAGGTTACT CTTGTTACTG TGACGGAAAG AAAGGATTCA AACTTGCCCA AGATCAGAAG 
AGTTGTGAGG CTGTTCCAGT GTGCCTTCCT TTGGACCTTG ACAAAAATTA TGAATTGCTT 
TACTTGGCAG AGCAGTTTGT AGGGGTTGTT TTGTATTTAA AATTTCGTTT GCCAGAAACT 
ACCAGATTTT CAGCTGAATT TGATTTCCGG ACATATGATT CAGAAGGTGT TATCCTGTAT 
GCAGAATCTT CTGATCACTC AGCTTGGTTC CTGATTGCGC TTCGTGAGGG AAAGATTGAA 
ATTCAGTTCA AGAATGAAAA GACAACCAAA ATGACAACTG GAGGCAAAGT TATTAATGAT 
GGTTTATGGC ATATGGTCTC TGTGGAAGAA TTAGAACAGA GTATTAGTGT AAAAATAGCT 
AAAGAAGCTG TAATGAATAT AAATAAGCCT GGAAGCCTTT TTAAGCCCAC CAATGGGTTT 
CTAGAAACCA AAGTATACTT TGCAGGAGTA CCTCGGAAAA TGGAAAATGC ACTCATTAGA 
CCGATTAACC CTCGTCTAGA TGGATGTATT CGAGGCTGGA ATTTGATGAA TCAAGGAACT 
TCAGGAGTAA AGGAAATCAT TCAAGAAAAA CAAAATAAGC ATTGTCTTGT CAATGTGGAG 
AAGGGTTCCT ACTATCCTGG TACTGGAGTT GCTCAGTTTA GCATAAATTA TAAGAATGAA 
TCCAATCCTG AGGCTTGGCA AATCAATGTG TCCTTGAATA TTCGCCCATC AGCGGGCACC 
GGTGTTATGT TGGCCTTGGT TTCCGATAAC ACAGTGCCCT TTGCCTTGTC CTTGGTGGAT 
TCCGCCACTG AAAAGCTTCA GGATATCCTG GTATCTGTTG AAAGTATGGT AATAGGTCGG 
ATAGAGGCCA TAAGTCTGTG TTCCGATCAG CAAACCTTTC TGGAAATCAG AGTCAACAGA 
AACAATTTGG AACTATCGAC TCAACTTAGA AAGGATAGCT TCCACTCTGA AGACTTTCAA 
AGACAATTTG CCATCTTGGA TGAAGCAATG AAAGGAACAG TGGTCACTTA CCTGGGTGGC 
CTTCCAGATG TTCCATTCAG TGCCACACCA GTGAATGCCT TTTATCAAGG CTGTATGGAA 
GTGAACATTA ATGGTGTACA GGTGGATTTG GATGAAGCCA TTTCTAAACA TAATGATATT 
AGAGCTCACT CGTGTCCATC AGTTTGGCAG AAGACAAAGC ATACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Prevention of thrombosis following deep arterial injury in rats by bovine activated protein C requiring co-administration of bovine protein S.
Thrombosis and haemostasis90(2)227-34(2003 Aug)
Malm K,Dahlb?ck B,Arnljots B

Primary structure of bovine vitamin K-dependent protein S.
Proceedings of the National Academy of Sciences of the United States of America83(12)4199-203(1986 Jun)
Dahlb?ck B,Lundwall A,Stenflo J

Localization of thrombin cleavage sites in the amino-terminal region of bovine protein S.
The Journal of biological chemistry261(11)5111-5(1986 Apr)
Dahlb?ck B,Lundwall A,Stenflo J

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PROS1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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