P2RY1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	P2RY1
Entrez Gene ID	281963
Full Name	purinergic receptor P2Y1
Synonyms	P2Y1
General protein information	Preferred Names purinergic receptor P2Y1 Names P2Y purinoceptor 1 ATP receptor p2y1 purinoceptor purinergic receptor P2Y, G-protein coupled, 1
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174410.3	NP_776835.1	P2Y purinoceptor 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	P2RY1	NP_002554.1
Mus musculus (house mouse)	P2ry1	NP_001268945.1
Gallus gallus (chicken)	P2RY1	NP_990664.1
Danio rerio (zebrafish)	LOC100003922	XP_001343355.1
Rattus norvegicus (Norway rat)	P2ry1	NP_036932.1
Canis lupus familiaris (dog)	P2RY1	NP_001180602.1
Pan troglodytes (chimpanzee)	P2RY1	XP_526353.1
	P2RY1	XP_001106445.1
Xenopus tropicalis (tropical clawed frog)	p2ry1	NP_001096222.1
Bos taurus (cattle)	P2RY1	NP_776835.1

Gene Ontology
Bibliography

Related articles in PubMed

Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium.
Kalwa H, Sartoretto JL, Martinelli R, Romero N, Steinhorn BS, Tao M, Ozaki CK, Carman CV, Michel T
Proceedings of the National Academy of Sciences of the United States of America111(9)3383-8(2014 Mar)

Purinergic P2Y1 receptor signaling mediates wound stimuli-induced cyclooxygenase-2 expression in intestinal subepithelial myofibroblasts.
Iwanaga K, Murata T, Hori M, Ozaki H
European journal of pharmacology702(1-3)158-64(2013 Feb)

P2Y1 and P2Y13 purinergic receptors mediate Ca2+ signaling and proliferative responses in pulmonary artery vasa vasorum endothelial cells.
Lyubchenko T, Woodward H, Veo KD, Burns N, Nijmeh H, Liubchenko GA, Stenmark KR, Gerasimovskaya EV
American journal of physiology. Cell physiology300(2)C266-75(2011 Feb)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Cloning and expression of a P2y purinoceptor from the adult bovine corpus callosum.
Deng G, Matute C, Kumar CK, Fogarty DJ, Miledi R
Neurobiology of disease5(4)259-70(1998 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

P2Y1 receptor-mediated responses involve Flt3 transactivation, and may identify a unique mechanism whereby cancer chemotherapy with receptor tyrosine kinase inhibitors promotes vascular dysfunction.
Title: Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium.

Purinergic P2Y1 receptor signaling mediates wound stimuli-induced cyclooxygenase-2 expression in intestinal subepithelial myofibroblasts.
Title: Purinergic P2Y1 receptor signaling mediates wound stimuli-induced cyclooxygenase-2 expression in intestinal subepithelial myofibroblasts.

P2Y1 and P2Y13 receptors play a major role in vasa vasorum endothelial cells growth responses.
Title: P2Y1 and P2Y13 purinergic receptors mediate Ca2+ signaling and proliferative responses in pulmonary artery vasa vasorum endothelial cells.

The following P2RY1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the P2RY1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa01485	NM_174410.3 Latest version!	Bos taurus purinergic receptor P2Y1 (P2RY1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

P2RY1 ( NM_174410.3 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776835.1 Bos taurus purinergic receptor P2Y1 (P2RY1), mRNA.

Price & Availability↑

CloneID	OBa01485
Clone ID Related Accession (Same CDS sequence)	NM_174410.3
Accession Version	NM_174410.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Bos taurus(cattle)
Product	P2Y purinoceptor 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from X87628.1. On Nov 15, 2014 this sequence version replaced NM_174410.2. ##Evidence-Data-START## Transcript is intronless :: X87628.1 [ECO:0000345] ##Evidence-Data-END##

ATGACCGAGG TGCTGTGGCC GGCGGTCCCC AACGGGACGG ACACTGCCTT CCTTGCCGAC 
CCTGGTTCGC CCTGGGGAAA CAGCACAGTG ACTTCCACCG CCGCCGTCGC CAGCCCGTTC 
AAATGCGCGC TGACCAAGAC AGGCTTCCAG TTCTACTACC TGCCAGCTGT CTACATCTTG 
GTGTTCATTA TCGGCTTCCT GGGCAACAGC GTGGCCATCT GGATGTTCGT CTTCCACATG 
AAGCCGTGGA GCGGCATCTC CGTGTACATG TTCAACTTGG CCCTGGCCGA CTTCTTGTAC 
GTGCTGACTC TGCCGGCGCT CATCTTCTAC TACTTCAATA AGACCGACTG GATCTTTGGG 
GATGCCATGT GCAAGCTGCA GAGGTTCATC TTCCACGTGA ACCTCTATGG CAGCATCTTA 
TTCCTGACCT GCATTAGCGC GCACCGGTAC AGCGGCGTGG TGTACCCGCT CAAGTCCCTG 
GGTAGGCTCA AGAAGAAGAA CGCGGTCTAT ATTAGCGTGC TGGTGTGGCT CATCGTGGTG 
GTGGGCATCT CCCCCATCCT CTTCTACTCT GGCACCGGGA TCCGGAAAAA CAAAACCATC 
ACCTGCTATG ACACCACCTC AGACGAGTAC CTGCGAAGTT ATTTCATCTA TAGTATGTGC 
ACGACCGTGG CCATGTTCTG TGTCCCCTTG GTGCTGATTT TGGGCTGTTA CGGATTAATT 
GTGAGAGCTC TGATTTACAA AGACCTGGAC AATTCGCCTC TGAGGAGGAA ATCCATTTAC 
CTGGTGATTA TTGTACTGAC TGTTTTTGCT GTGTCTTACA TCCCTTTCCA CGTGATGAAA 
ACAATGAATT TGAGGGCCCG GCTGGATTTT CAGACCCCAG AAATGTGTGC TTTCAATGAT 
AGGGTGTATG CCACTTATCA GGTGACAAGA GGTCTAGCAA GTCTCAACAG TTGTGTGGAC 
CCCATTCTCT ATTTCTTGGC AGGAGATACT TTCAGAAGGA GACTCTCCCG AGCCACCAGG 
AAGGCTTCCA GAAGAAGTGA GGCAAACTTG CAGTCCAAGA GTGAAGACAT GACACTCAAT 
ATTTTATCAG AGTTCAAGCA GAATGGAGAT ACAAGCTTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776835.1
CDS	372..1493
Translation	MTEVLWPAVPNGTDTAFLADPGSPWGNSTVTSTAAVASPFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAVYISVLVWLIVVVGISPILFYSGTGIRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILSEFKQNGDTSL

Target ORF information:

RefSeq Version	NM_174410.3
Organism	Bos taurus(cattle)
Definition	Bos taurus purinergic receptor P2Y1 (P2RY1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174410.3

ORF Insert Sequence:

ATGACCGAGG TGCTGTGGCC GGCGGTCCCC AACGGGACGG ACACTGCCTT CCTTGCCGAC 
CCTGGTTCGC CCTGGGGAAA CAGCACAGTG ACTTCCACCG CCGCCGTCGC CAGCCCGTTC 
AAATGCGCGC TGACCAAGAC AGGCTTCCAG TTCTACTACC TGCCAGCTGT CTACATCTTG 
GTGTTCATTA TCGGCTTCCT GGGCAACAGC GTGGCCATCT GGATGTTCGT CTTCCACATG 
AAGCCGTGGA GCGGCATCTC CGTGTACATG TTCAACTTGG CCCTGGCCGA CTTCTTGTAC 
GTGCTGACTC TGCCGGCGCT CATCTTCTAC TACTTCAATA AGACCGACTG GATCTTTGGG 
GATGCCATGT GCAAGCTGCA GAGGTTCATC TTCCACGTGA ACCTCTATGG CAGCATCTTA 
TTCCTGACCT GCATTAGCGC GCACCGGTAC AGCGGCGTGG TGTACCCGCT CAAGTCCCTG 
GGTAGGCTCA AGAAGAAGAA CGCGGTCTAT ATTAGCGTGC TGGTGTGGCT CATCGTGGTG 
GTGGGCATCT CCCCCATCCT CTTCTACTCT GGCACCGGGA TCCGGAAAAA CAAAACCATC 
ACCTGCTATG ACACCACCTC AGACGAGTAC CTGCGAAGTT ATTTCATCTA TAGTATGTGC 
ACGACCGTGG CCATGTTCTG TGTCCCCTTG GTGCTGATTT TGGGCTGTTA CGGATTAATT 
GTGAGAGCTC TGATTTACAA AGACCTGGAC AATTCGCCTC TGAGGAGGAA ATCCATTTAC 
CTGGTGATTA TTGTACTGAC TGTTTTTGCT GTGTCTTACA TCCCTTTCCA CGTGATGAAA 
ACAATGAATT TGAGGGCCCG GCTGGATTTT CAGACCCCAG AAATGTGTGC TTTCAATGAT 
AGGGTGTATG CCACTTATCA GGTGACAAGA GGTCTAGCAA GTCTCAACAG TTGTGTGGAC 
CCCATTCTCT ATTTCTTGGC AGGAGATACT TTCAGAAGGA GACTCTCCCG AGCCACCAGG 
AAGGCTTCCA GAAGAAGTGA GGCAAACTTG CAGTCCAAGA GTGAAGACAT GACACTCAAT 
ATTTTATCAG AGTTCAAGCA GAATGGAGAT ACAAGCTTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium.
Proceedings of the National Academy of Sciences of the United States of America111(9)3383-8(2014 Mar)
Kalwa H,Sartoretto JL,Martinelli R,Romero N,Steinhorn BS,Tao M,Ozaki CK,Carman CV,Michel T

Purinergic P2Y1 receptor signaling mediates wound stimuli-induced cyclooxygenase-2 expression in intestinal subepithelial myofibroblasts.
European journal of pharmacology702(1-3)158-64(2013 Feb)
Iwanaga K,Murata T,Hori M,Ozaki H

P2Y1 and P2Y13 purinergic receptors mediate Ca2+ signaling and proliferative responses in pulmonary artery vasa vasorum endothelial cells.
American journal of physiology. Cell physiology300(2)C266-75(2011 Feb)
Lyubchenko T,Woodward H,Veo KD,Burns N,Nijmeh H,Liubchenko GA,Stenmark KR,Gerasimovskaya EV

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Cloning and expression of a P2y purinoceptor from the adult bovine corpus callosum.
Neurobiology of disease5(4)259-70(1998 Oct)
Deng G,Matute C,Kumar CK,Fogarty DJ,Miledi R

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P2RY1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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