ITGA2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITGA2
Entrez Gene ID	281872
Full Name	integrin subunit alpha 2
General protein information	Preferred Names integrin subunit alpha 2 Names integrin alpha-2 CD49 antigen-like family member B GPIa VLA-2 alpha chain VLA-2 subunit alpha collagen receptor integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) platelet membrane glycoprotein Ia
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001166499.1	NP_001159971.1	integrin alpha-2 precursor
XM_024981212.1	XP_024836980.1	integrin alpha-2 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ITGA2	NP_001159971.1
Mus musculus (house mouse)	Itga2	NP_032422.2
Gallus gallus (chicken)	ITGA2	XP_003643030.2
Danio rerio (zebrafish)	itga2.2	XP_003199352.2
	ITGA2	XP_001095246.1
Canis lupus familiaris (dog)	ITGA2	XP_005619391.1
Rattus norvegicus (Norway rat)	Itga2	XP_345157.5
Pan troglodytes (chimpanzee)	ITGA2	XP_526928.2
Xenopus tropicalis (tropical clawed frog)	itga2	XP_002933089.2
Homo sapiens (human)	ITGA2	NP_002194.2
Danio rerio (zebrafish)	LOC100333484	XP_003199351.2

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

A mechanism to safeguard platelet adhesion under high shear flow: von Willebrand factor-glycoprotein Ib and integrin alphabeta-collagen interactions make complementary, collagen-type-specific contributions to adhesion.
Moroi M, Jung SM
Journal of thrombosis and haemostasis : JTH5(4)797-803(2007 Apr)

Matrix-specific suppression of integrin activation in shear stress signaling.
Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA
Molecular biology of the cell17(11)4686-97(2006 Nov)

Identification of putative ligand binding sites within I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29)
Kamata T, Puzon W, Takada Y
The Journal of biological chemistry269(13)9659-63(1994 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

both the gpIb-VWF interaction and the integrin alpha(2)beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II)beta(1) makes a greater contribution to adhesion to type I collagen because less VWF is bound
Title: A mechanism to safeguard platelet adhesion under high shear flow: von Willebrand factor-glycoprotein Ib and integrin alphabeta-collagen interactions make complementary, collagen-type-specific contributions to adhesion.

Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
Title: Matrix-specific suppression of integrin activation in shear stress signaling.

The following ITGA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITGA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa227960	XM_024981212.1 Latest version!	Bos taurus integrin subunit alpha 2 (ITGA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OBa44460	NM_001166499.1 Latest version!	Bos taurus integrin subunit alpha 2 (ITGA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$713.30 $1019.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITGA2 ( XM_024981212.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024836980.1 Bos taurus integrin subunit alpha 2 (ITGA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa227960
Clone ID Related Accession (Same CDS sequence)	XM_024981212.1
Accession Version	XM_024981212.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	integrin alpha-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037347.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGTTAA TTCAATATGC CAATAATCCA AGAGTTGTGT TTAACCTGAA TACTTTTAAA 
TCCAAAGATG AAATGATTAA AGCAACATCG CAGACATTCC AATATGGTGG AGACCTTACA 
AATACCTTCA AAGCAATTCA GTATGCAAGA GATACCGCTT ATTCAACGGC TGCTGGTGGA 
CGACCAGGTG CTACCAAAGT TATGGTGGTT GTAACTGATG GTGAATCCCA TGATGGTTCA 
AAGTTGAAAG CTGTGATTGA TCAATGTAAC AAAGACAATA TACTGAGGTT TGGCATAGCA 
GTTCTTGGGT ACTTAAACAG AAACGCCCTG GATACTAAAA ATTTAATAAA GGAAATTAAA 
GCTATTGCCA GTATTCCAAC AGAAAGACAC TTTTTCAATG TCTCTGATGA AGCAGATCTA 
CTAGAAAAGG CTGGGACAAT AGGAGAACAA ATTTTCAGCA TTGAAGGTAC AGTTCAAGGA 
GGAGACAACT TCCAAATGGA AATGTCGCAA GTGGGATTCA GCGCGGAATA CTCTCCTCAA 
AATAATATTC TGATGCTGGG TGCAGTAGGA GCTTACGACT GGAGTGGGAC TGTGGTGCAG 
AAGACACCTC ATGGACATTT GATCTTTTCT AAACAAGCGT TTGAACAAAT TCTGCAAGAC 
AGAAATCACA GTTCATATTT AGGTTACTCT GTGGCTTCAA TTTCTACTGG GAACAGTGTC 
CACTTTGTTG CTGGTGCTCC TCGAGCAAAT TATACTGGCC AGATAGTGCT CTACAGTGTT 
AATGAGAATG GCAATGTCAC AGTTATTCAG TCTCACAGAG GTGACCAGAT TGGCTCCTAT 
TTTGGTAGTG TGCTGTGTGC AGTCGATGTG AATAAGGACA CCATTACAGA TGTGCTCTTG 
GTAGGTGCAC CAATGTACAT GAATGACCTA AAGAAAGAGG AAGGAAGAGT CTACCTGTTT 
ACTATTACAA AGGGCATTTT GAATTGGCAC CAATTTCTGG AAGGCCCCAA GGGTCTTGAA 
AATGCTCGAT TTGGTTCAGC AATTGCAGCT CTTTCAGACA TCAACATGGA TGGCTTTAAT 
GACGTGATTG TTGGTTCGCC TTTGGAAAAT CAGAACTCTG GAGCTGTGTA CATCTACAAT 
GGTCATGAGG GCATGATTCG CTTGAGGTAT TCTCAGAAAA TCCTGGGGTC CGACAGAGCC 
TTTAGTAGCC ACCTCCAGTA CTTTGGGAGA TCCCTGGATG GCTATGGAGA TTTAAATGGG 
GATTCCATCA CCGACGTGTC CGTGGGGGCC TTTGGACAGG TCGTTCAGCT CTGGTCACAG 
AGCATTGCTG ATGTATCTGT AGATGCTTCA TTCACACCAA AAAAAATCAC TTTGCTCAAC 
AAAAATGCTG AGATAAAACT TAAACTCTGC TTCAGTGCTA AGTTTAGACC TACTAATCAA 
AACAATCAAG TGGCCATTGT GTATAACATC ACAATTGATG AAGACCAGTT TTCATCCAGA 
GTGATATCCA GGGGGTTATT TAAGGAAAAT AATGAAAGGT GCTTGCAGAA GACCATGATA 
GTAAGTCAAG CACAGCGCTG TTCTGAGTAC ATCATCCACA TACAGGAGCC CTCTGACATT 
ATCAGCCCTC TGAATCTGTG TATGAACATT AGTCTGGAAA ACCCTGGCAC TAACCCTGCC 
CTTGAAGCCT ACTCTGAGAC GGTCAAGGTC TTCAGTATCC CTTTCCATAA AGACTGTGGT 
GATGATGGAG TTTGCATTTC TGATCTAGTT CTAAATGTTC AGCAGCTGCC AGCCACTCAA 
CAACAGCCCT TCATTGTCAG CAACCAAAAC AAAAGGTTAA CATTTTCAGT ACAACTGAAA 
AACAAGAAGG AAAGTGCCTA CAACACTGAG ATTGTTGTTG ATTTTTCAGA AAACCTGTTT 
TTTGCTTCCT GGTCCATGCC GGTTGATGGG ACAGAAGTGA CCTGCCAGAT TGCTTCATCT 
CAGAAGTCTG TTACCTGCAA TGTGGGCTAC CCTGCTTTAA AGAGCAAACA ACAGGTGACT 
TTCACTATTA ACTTCGACTT CAATCTTCAA AACCTTCAGA ATCAGGCATC TATCAGTTTC 
CGAGCCTTAA GCGAAAGCCA GGAAGAAAAC ATGGCAGATA ATTCAGTCAA CTTAAAACTC 
TCTCTGCTGT ATGATGCCGA AATTCACATA ACAAGATCTA CCAACATAAA TTTTTATGAA 
GTCTCCTTGG ATGGGAATGT TTCTTCTGTC GTGCACAGTT TTGAAGATAT TGGTCCAAAA 
TTCATCTTCT CCATTAAGGT AACAACAGGA AGTGTTCCAG TAAGCATGGC ATCTGTGATC 
ATCCACATCC CTCAATACAC CAAAGACAAG AACCCACTGA TGTACCTGAC CGGGGTGCAC 
ACAGATCAGG CTGGTGACAT CAGTTGCGAA GCCGAAATAA ATCCACTGAA AATAGGACAG 
ACGTCTTCTT CTGTATCTTT CAAGAGTGAA AATTTCCGGC ACATAAAAGA ATTGAACTGT 
AGAACCGCTT CATGCAGTAA CATCATGTGC TGGCTGAGAG ACCTTCAGGT GAAAGGAGAA 
TACTTCCTTA ATGTGTCCAC CAGGATTTGG AATGGGACTT TCGCAGCATC GACTTTCCAG 
ACAGTACAGT TGACAGCAGC TGCAGAAATT GACACATATA ACCCTCAGAT ATACGTGATC 
GAAGAAAACA CGGTGACGAT TCCCCTTACG ATAATGAAAC CCCATGAGAA AGTTGAAGTA 
CCGACTGGAG TGATAGTAGG AAGTGTAATC GCTGGAATCC TTTTGCTATT AGCTCTAGTT 
GCAATTTTAT GGAAGCTTGG ATTCTTCAAA AGAAAATATG AAAAAATGGC CAAAAATCCA 
GATGAAACCG ATGAGACCAC AGAACTCAAC AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024836980.1
CDS	124..3039
Translation	MGLIQYANNPRVVFNLNTFKSKDEMIKATSQTFQYGGDLTNTFKAIQYARDTAYSTAAGGRPGATKVMVVVTDGESHDGSKLKAVIDQCNKDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERHFFNVSDEADLLEKAGTIGEQIFSIEGTVQGGDNFQMEMSQVGFSAEYSPQNNILMLGAVGAYDWSGTVVQKTPHGHLIFSKQAFEQILQDRNHSSYLGYSVASISTGNSVHFVAGAPRANYTGQIVLYSVNENGNVTVIQSHRGDQIGSYFGSVLCAVDVNKDTITDVLLVGAPMYMNDLKKEEGRVYLFTITKGILNWHQFLEGPKGLENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGMIRLRYSQKILGSDRAFSSHLQYFGRSLDGYGDLNGDSITDVSVGAFGQVVQLWSQSIADVSVDASFTPKKITLLNKNAEIKLKLCFSAKFRPTNQNNQVAIVYNITIDEDQFSSRVISRGLFKENNERCLQKTMIVSQAQRCSEYIIHIQEPSDIISPLNLCMNISLENPGTNPALEAYSETVKVFSIPFHKDCGDDGVCISDLVLNVQQLPATQQQPFIVSNQNKRLTFSVQLKNKKESAYNTEIVVDFSENLFFASWSMPVDGTEVTCQIASSQKSVTCNVGYPALKSKQQVTFTINFDFNLQNLQNQASISFRALSESQEENMADNSVNLKLSLLYDAEIHITRSTNINFYEVSLDGNVSSVVHSFEDIGPKFIFSIKVTTGSVPVSMASVIIHIPQYTKDKNPLMYLTGVHTDQAGDISCEAEINPLKIGQTSSSVSFKSENFRHIKELNCRTASCSNIMCWLRDLQVKGEYFLNVSTRIWNGTFAASTFQTVQLTAAAEIDTYNPQIYVIEENTVTIPLTIMKPHEKVEVPTGVIVGSVIAGILLLLALVAILWKLGFFKRKYEKMAKNPDETDETTELNS

Target ORF information:

RefSeq Version	XM_024981212.1
Organism	Bos taurus(cattle)
Definition	Bos taurus integrin subunit alpha 2 (ITGA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024981212.1

ORF Insert Sequence:

ATGGGGTTAA TTCAATATGC CAATAATCCA AGAGTTGTGT TTAACCTGAA TACTTTTAAA 
TCCAAAGATG AAATGATTAA AGCAACATCG CAGACATTCC AATATGGTGG AGACCTTACA 
AATACCTTCA AAGCAATTCA GTATGCAAGA GATACCGCTT ATTCAACGGC TGCTGGTGGA 
CGACCAGGTG CTACCAAAGT TATGGTGGTT GTAACTGATG GTGAATCCCA TGATGGTTCA 
AAGTTGAAAG CTGTGATTGA TCAATGTAAC AAAGACAATA TACTGAGGTT TGGCATAGCA 
GTTCTTGGGT ACTTAAACAG AAACGCCCTG GATACTAAAA ATTTAATAAA GGAAATTAAA 
GCTATTGCCA GTATTCCAAC AGAAAGACAC TTTTTCAATG TCTCTGATGA AGCAGATCTA 
CTAGAAAAGG CTGGGACAAT AGGAGAACAA ATTTTCAGCA TTGAAGGTAC AGTTCAAGGA 
GGAGACAACT TCCAAATGGA AATGTCGCAA GTGGGATTCA GCGCGGAATA CTCTCCTCAA 
AATAATATTC TGATGCTGGG TGCAGTAGGA GCTTACGACT GGAGTGGGAC TGTGGTGCAG 
AAGACACCTC ATGGACATTT GATCTTTTCT AAACAAGCGT TTGAACAAAT TCTGCAAGAC 
AGAAATCACA GTTCATATTT AGGTTACTCT GTGGCTTCAA TTTCTACTGG GAACAGTGTC 
CACTTTGTTG CTGGTGCTCC TCGAGCAAAT TATACTGGCC AGATAGTGCT CTACAGTGTT 
AATGAGAATG GCAATGTCAC AGTTATTCAG TCTCACAGAG GTGACCAGAT TGGCTCCTAT 
TTTGGTAGTG TGCTGTGTGC AGTCGATGTG AATAAGGACA CCATTACAGA TGTGCTCTTG 
GTAGGTGCAC CAATGTACAT GAATGACCTA AAGAAAGAGG AAGGAAGAGT CTACCTGTTT 
ACTATTACAA AGGGCATTTT GAATTGGCAC CAATTTCTGG AAGGCCCCAA GGGTCTTGAA 
AATGCTCGAT TTGGTTCAGC AATTGCAGCT CTTTCAGACA TCAACATGGA TGGCTTTAAT 
GACGTGATTG TTGGTTCGCC TTTGGAAAAT CAGAACTCTG GAGCTGTGTA CATCTACAAT 
GGTCATGAGG GCATGATTCG CTTGAGGTAT TCTCAGAAAA TCCTGGGGTC CGACAGAGCC 
TTTAGTAGCC ACCTCCAGTA CTTTGGGAGA TCCCTGGATG GCTATGGAGA TTTAAATGGG 
GATTCCATCA CCGACGTGTC CGTGGGGGCC TTTGGACAGG TCGTTCAGCT CTGGTCACAG 
AGCATTGCTG ATGTATCTGT AGATGCTTCA TTCACACCAA AAAAAATCAC TTTGCTCAAC 
AAAAATGCTG AGATAAAACT TAAACTCTGC TTCAGTGCTA AGTTTAGACC TACTAATCAA 
AACAATCAAG TGGCCATTGT GTATAACATC ACAATTGATG AAGACCAGTT TTCATCCAGA 
GTGATATCCA GGGGGTTATT TAAGGAAAAT AATGAAAGGT GCTTGCAGAA GACCATGATA 
GTAAGTCAAG CACAGCGCTG TTCTGAGTAC ATCATCCACA TACAGGAGCC CTCTGACATT 
ATCAGCCCTC TGAATCTGTG TATGAACATT AGTCTGGAAA ACCCTGGCAC TAACCCTGCC 
CTTGAAGCCT ACTCTGAGAC GGTCAAGGTC TTCAGTATCC CTTTCCATAA AGACTGTGGT 
GATGATGGAG TTTGCATTTC TGATCTAGTT CTAAATGTTC AGCAGCTGCC AGCCACTCAA 
CAACAGCCCT TCATTGTCAG CAACCAAAAC AAAAGGTTAA CATTTTCAGT ACAACTGAAA 
AACAAGAAGG AAAGTGCCTA CAACACTGAG ATTGTTGTTG ATTTTTCAGA AAACCTGTTT 
TTTGCTTCCT GGTCCATGCC GGTTGATGGG ACAGAAGTGA CCTGCCAGAT TGCTTCATCT 
CAGAAGTCTG TTACCTGCAA TGTGGGCTAC CCTGCTTTAA AGAGCAAACA ACAGGTGACT 
TTCACTATTA ACTTCGACTT CAATCTTCAA AACCTTCAGA ATCAGGCATC TATCAGTTTC 
CGAGCCTTAA GCGAAAGCCA GGAAGAAAAC ATGGCAGATA ATTCAGTCAA CTTAAAACTC 
TCTCTGCTGT ATGATGCCGA AATTCACATA ACAAGATCTA CCAACATAAA TTTTTATGAA 
GTCTCCTTGG ATGGGAATGT TTCTTCTGTC GTGCACAGTT TTGAAGATAT TGGTCCAAAA 
TTCATCTTCT CCATTAAGGT AACAACAGGA AGTGTTCCAG TAAGCATGGC ATCTGTGATC 
ATCCACATCC CTCAATACAC CAAAGACAAG AACCCACTGA TGTACCTGAC CGGGGTGCAC 
ACAGATCAGG CTGGTGACAT CAGTTGCGAA GCCGAAATAA ATCCACTGAA AATAGGACAG 
ACGTCTTCTT CTGTATCTTT CAAGAGTGAA AATTTCCGGC ACATAAAAGA ATTGAACTGT 
AGAACCGCTT CATGCAGTAA CATCATGTGC TGGCTGAGAG ACCTTCAGGT GAAAGGAGAA 
TACTTCCTTA ATGTGTCCAC CAGGATTTGG AATGGGACTT TCGCAGCATC GACTTTCCAG 
ACAGTACAGT TGACAGCAGC TGCAGAAATT GACACATATA ACCCTCAGAT ATACGTGATC 
GAAGAAAACA CGGTGACGAT TCCCCTTACG ATAATGAAAC CCCATGAGAA AGTTGAAGTA 
CCGACTGGAG TGATAGTAGG AAGTGTAATC GCTGGAATCC TTTTGCTATT AGCTCTAGTT 
GCAATTTTAT GGAAGCTTGG ATTCTTCAAA AGAAAATATG AAAAAATGGC CAAAAATCCA 
GATGAAACCG ATGAGACCAC AGAACTCAAC AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGA2 ( NM_001166499.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001159971.1 Bos taurus integrin subunit alpha 2 (ITGA2), mRNA.

Price & Availability↑

CloneID	OBa44460
Clone ID Related Accession (Same CDS sequence)	NM_001166499.1
Accession Version	NM_001166499.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Bos taurus(cattle)
Product	integrin alpha-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from NKLS02000020.1. On Oct 28, 2009 this sequence version replaced XM_613651.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: L25886.1, SRR5721698.2568.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END##

ATGCGGCCAG GACGGACAGG CGGCACGCCG CTGCAGCTGG TGTTAGTGTT CAGTCAAGGC 
ATTTTAAACT GTTGTGTGGC ATACAACGTT GGTCTCCCAA AAGCAAAGAT ATTTTCTGGT 
CCTTCAAGTG AACAGTTTGG CTATGCAGTG CAGCAGTTTA TAAATCCAAA AGGCAACTGG 
TTACTGGTTG GTTCACCATG GAGTGGCTTT CCTAAGAACC GAATGGGAGA TGTATATAAA 
TGTCCTGTTG ATCTATCCAC CACTACATGT GAAAAATTGA ATTTGCAAAC TTCCACGAGC 
ATGTCCAATG TTACTGAGAT GAAAACCAAC ATGAGCCTTG GCTTGACACT GACAAGGAAC 
GTGGGAACAG GAGGATTTCT TACCTGTGGT CCCCTGTGGG CACAGCAGTG TGGAAGTCAG 
TATTACACAA CTGGCGTTTG CTCTGATGTC AGTCCTGATT TTCAGTTGCG GACCAGCTTT 
GCGCCTGCAG TTCAGACCTG CCCTTCCTTC ATAGATGTTG TGGTTGTATG TGATGAATCA 
AACAGTATTT ATCCCTGGGA TGCAGTAAAG AACTTTTTGG AAAAATTTGT ACAAGGCCTA 
GATATAGGCC CCACAAAGAC ACAGATGGGG TTAATTCAAT ATGCCAATAA TCCAAGAGTT 
GTGTTTAACC TGAATACTTT TAAATCCAAA GATGAAATGA TTAAAGCAAC ATCGCAGACA 
TTCCAATATG GTGGAGACCT TACAAATACC TTCAAAGCAA TTCAGTATGC AAGAGATACC 
GCTTATTCAA CGGCTGCTGG TGGACGACCA GGTGCTACCA AAGTTATGGT GGTTGTAACT 
GATGGTGAAT CCCATGATGG TTCAAAGTTG AAAGCTGTGA TTGATCAATG TAACAAAGAC 
AATATACTGA GGTTTGGCAT AGCAGTTCTT GGGTACTTAA ACAGAAACGC CCTGGATACT 
AAAAATTTAA TAAAGGAAAT TAAAGCTATT GCCAGTATTC CAACAGAAAG ACACTTTTTC 
AATGTCTCTG ATGAAGCAGA TCTACTAGAA AAGGCTGGGA CAATAGGAGA ACAAATTTTC 
AGCATTGAAG GTACAGTTCA AGGAGGAGAC AACTTCCAAA TGGAAATGTC GCAAGTGGGA 
TTCAGCGCGG AATACTCTCC TCAAAATAAT ATTCTGATGC TGGGTGCAGT AGGAGCTTAC 
GACTGGAGTG GGACTGTGGT GCAGAAGACA CCTCATGGAC ATTTGATCTT TTCTAAACAA 
GCGTTTGAAC AAATTCTGCA AGACAGAAAT CACAGTTCAT ATTTAGGTTA CTCTGTGGCT 
TCAATTTCTA CTGGGAACAG TGTCCACTTT GTTGCTGGTG CTCCTCGAGC AAATTATACT 
GGCCAGATAG TGCTCTACAG TGTTAATGAG AATGGCAATG TCACAGTTAT TCAGTCTCAC 
AGAGGTGACC AGATTGGCTC CTATTTTGGT AGTGTGCTGT GTGCAGTCGA TGTGAATAAG 
GACACCATTA CAGATGTGCT CTTGGTAGGT GCACCAATGT ACATGAATGA CCTAAAGAAA 
GAGGAAGGAA GAGTCTACCT GTTTACTATT ACAAAGGGCA TTTTGAATTG GCACCAATTT 
CTGGAAGGCC CCAAGGGTCT TGAAAATGCT CGATTTGGTT CAGCAATTGC AGCTCTTTCA 
GACATCAACA TGGATGGCTT TAATGACGTG ATTGTTGGTT CGCCTTTGGA AAATCAGAAC 
TCTGGAGCTG TGTACATCTA CAATGGTCAT GAGGGCATGA TTCGCTTGAG GTATTCTCAG 
AAAATCCTGG GGTCCGACAG AGCCTTTAGT AGCCACCTCC AGTACTTTGG GAGATCCCTG 
GATGGCTATG GAGATTTAAA TGGGGATTCC ATCACCGACG TGTCCGTGGG GGCCTTTGGA 
CAGGTCGTTC AGCTCTGGTC ACAGAGCATT GCTGATGTAT CTGTAGATGC TTCATTCACA 
CCAAAAAAAA TCACTTTGCT CAACAAAAAT GCTGAGATAA AACTTAAACT CTGCTTCAGT 
GCTAAGTTTA GACCTACTAA TCAAAACAAT CAAGTGGCCA TTGTGTATAA CATCACAATT 
GATGAAGACC AGTTTTCATC CAGAGTGATA TCCAGGGGGT TATTTAAGGA AAATAATGAA 
AGGTGCTTGC AGAAGACCAT GATAGTAAGT CAAGCACAGC GCTGTTCTGA GTACATCATC 
CACATACAGG AGCCCTCTGA CATTATCAGC CCTCTGAATC TGTGTATGAA CATTAGTCTG 
GAAAACCCTG GCACTAACCC TGCCCTTGAA GCCTACTCTG AGACGGTCAA GGTCTTCAGT 
ATCCCTTTCC ATAAAGACTG TGGTGATGAT GGAGTTTGCA TTTCTGATCT AGTTCTAAAT 
GTTCAGCAGC TGCCAGCCAC TCAACAACAG CCCTTCATTG TCAGCAACCA AAACAAAAGG 
TTAACATTTT CAGTACAACT GAAAAACAAG AAGGAAAGTG CCTACAACAC TGAGATTGTT 
GTTGATTTTT CAGAAAACCT GTTTTTTGCT TCCTGGTCCA TGCCGGTTGA TGGGACAGAA 
GTGACCTGCC AGATTGCTTC ATCTCAGAAG TCTGTTACCT GCAATGTGGG CTACCCTGCT 
TTAAAGAGCA AACAACAGGT GACTTTCACT ATTAACTTCG ACTTCAATCT TCAAAACCTT 
CAGAATCAGG CATCTATCAG TTTCCGAGCC TTAAGCGAAA GCCAGGAAGA AAACATGGCA 
GATAATTCAG TCAACTTAAA ACTCTCTCTG CTGTATGATG CCGAAATTCA CATAACAAGA 
TCTACCAACA TAAATTTTTA TGAAGTCTCC TTGGATGGGA ATGTTTCTTC TGTCGTGCAC 
AGTTTTGAAG ATATTGGTCC AAAATTCATC TTCTCCATTA AGGTAACAAC AGGAAGTGTT 
CCAGTAAGCA TGGCATCTGT GATCATCCAC ATCCCTCAAT ACACCAAAGA CAAGAACCCA 
CTGATGTACC TGACCGGGGT GCACACAGAT CAGGCTGGTG ACATCAGTTG CGAAGCCGAA 
ATAAATCCAC TGAAAATAGG ACAGACGTCT TCTTCTGTAT CTTTCAAGAG TGAAAATTTC 
CGGCACATAA AAGAATTGAA CTGTAGAACC GCTTCATGCA GTAACATCAT GTGCTGGCTG 
AGAGACCTTC AGGTGAAAGG AGAATACTTC CTTAATGTGT CCACCAGGAT TTGGAATGGG 
ACTTTCGCAG CATCGACTTT CCAGACAGTA CAGTTGACAG CAGCTGCAGA AATTGACACA 
TATAACCCTC AGATATACGT GATCGAAGAA AACACGGTGA CGATTCCCCT TACGATAATG 
AAACCCCATG AGAAAGTTGA AGTACCGACT GGAGTGATAG TAGGAAGTGT AATCGCTGGA 
ATCCTTTTGC TATTAGCTCT AGTTGCAATT TTATGGAAGC TTGGATTCTT CAAAAGAAAA 
TATGAAAAAA TGGCCAAAAA TCCAGATGAA ACCGATGAGA CCACAGAACT CAACAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159971.1
CDS	1..3540
Translation	MRPGRTGGTPLQLVLVFSQGILNCCVAYNVGLPKAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPKNRMGDVYKCPVDLSTTTCEKLNLQTSTSMSNVTEMKTNMSLGLTLTRNVGTGGFLTCGPLWAQQCGSQYYTTGVCSDVSPDFQLRTSFAPAVQTCPSFIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQMGLIQYANNPRVVFNLNTFKSKDEMIKATSQTFQYGGDLTNTFKAIQYARDTAYSTAAGGRPGATKVMVVVTDGESHDGSKLKAVIDQCNKDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERHFFNVSDEADLLEKAGTIGEQIFSIEGTVQGGDNFQMEMSQVGFSAEYSPQNNILMLGAVGAYDWSGTVVQKTPHGHLIFSKQAFEQILQDRNHSSYLGYSVASISTGNSVHFVAGAPRANYTGQIVLYSVNENGNVTVIQSHRGDQIGSYFGSVLCAVDVNKDTITDVLLVGAPMYMNDLKKEEGRVYLFTITKGILNWHQFLEGPKGLENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGMIRLRYSQKILGSDRAFSSHLQYFGRSLDGYGDLNGDSITDVSVGAFGQVVQLWSQSIADVSVDASFTPKKITLLNKNAEIKLKLCFSAKFRPTNQNNQVAIVYNITIDEDQFSSRVISRGLFKENNERCLQKTMIVSQAQRCSEYIIHIQEPSDIISPLNLCMNISLENPGTNPALEAYSETVKVFSIPFHKDCGDDGVCISDLVLNVQQLPATQQQPFIVSNQNKRLTFSVQLKNKKESAYNTEIVVDFSENLFFASWSMPVDGTEVTCQIASSQKSVTCNVGYPALKSKQQVTFTINFDFNLQNLQNQASISFRALSESQEENMADNSVNLKLSLLYDAEIHITRSTNINFYEVSLDGNVSSVVHSFEDIGPKFIFSIKVTTGSVPVSMASVIIHIPQYTKDKNPLMYLTGVHTDQAGDISCEAEINPLKIGQTSSSVSFKSENFRHIKELNCRTASCSNIMCWLRDLQVKGEYFLNVSTRIWNGTFAASTFQTVQLTAAAEIDTYNPQIYVIEENTVTIPLTIMKPHEKVEVPTGVIVGSVIAGILLLLALVAILWKLGFFKRKYEKMAKNPDETDETTELNS

Target ORF information:

RefSeq Version	NM_001166499.1
Organism	Bos taurus(cattle)
Definition	Bos taurus integrin subunit alpha 2 (ITGA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166499.1

ORF Insert Sequence:

ATGCGGCCAG GACGGACAGG CGGCACGCCG CTGCAGCTGG TGTTAGTGTT CAGTCAAGGC 
ATTTTAAACT GTTGTGTGGC ATACAACGTT GGTCTCCCAA AAGCAAAGAT ATTTTCTGGT 
CCTTCAAGTG AACAGTTTGG CTATGCAGTG CAGCAGTTTA TAAATCCAAA AGGCAACTGG 
TTACTGGTTG GTTCACCATG GAGTGGCTTT CCTAAGAACC GAATGGGAGA TGTATATAAA 
TGTCCTGTTG ATCTATCCAC CACTACATGT GAAAAATTGA ATTTGCAAAC TTCCACGAGC 
ATGTCCAATG TTACTGAGAT GAAAACCAAC ATGAGCCTTG GCTTGACACT GACAAGGAAC 
GTGGGAACAG GAGGATTTCT TACCTGTGGT CCCCTGTGGG CACAGCAGTG TGGAAGTCAG 
TATTACACAA CTGGCGTTTG CTCTGATGTC AGTCCTGATT TTCAGTTGCG GACCAGCTTT 
GCGCCTGCAG TTCAGACCTG CCCTTCCTTC ATAGATGTTG TGGTTGTATG TGATGAATCA 
AACAGTATTT ATCCCTGGGA TGCAGTAAAG AACTTTTTGG AAAAATTTGT ACAAGGCCTA 
GATATAGGCC CCACAAAGAC ACAGATGGGG TTAATTCAAT ATGCCAATAA TCCAAGAGTT 
GTGTTTAACC TGAATACTTT TAAATCCAAA GATGAAATGA TTAAAGCAAC ATCGCAGACA 
TTCCAATATG GTGGAGACCT TACAAATACC TTCAAAGCAA TTCAGTATGC AAGAGATACC 
GCTTATTCAA CGGCTGCTGG TGGACGACCA GGTGCTACCA AAGTTATGGT GGTTGTAACT 
GATGGTGAAT CCCATGATGG TTCAAAGTTG AAAGCTGTGA TTGATCAATG TAACAAAGAC 
AATATACTGA GGTTTGGCAT AGCAGTTCTT GGGTACTTAA ACAGAAACGC CCTGGATACT 
AAAAATTTAA TAAAGGAAAT TAAAGCTATT GCCAGTATTC CAACAGAAAG ACACTTTTTC 
AATGTCTCTG ATGAAGCAGA TCTACTAGAA AAGGCTGGGA CAATAGGAGA ACAAATTTTC 
AGCATTGAAG GTACAGTTCA AGGAGGAGAC AACTTCCAAA TGGAAATGTC GCAAGTGGGA 
TTCAGCGCGG AATACTCTCC TCAAAATAAT ATTCTGATGC TGGGTGCAGT AGGAGCTTAC 
GACTGGAGTG GGACTGTGGT GCAGAAGACA CCTCATGGAC ATTTGATCTT TTCTAAACAA 
GCGTTTGAAC AAATTCTGCA AGACAGAAAT CACAGTTCAT ATTTAGGTTA CTCTGTGGCT 
TCAATTTCTA CTGGGAACAG TGTCCACTTT GTTGCTGGTG CTCCTCGAGC AAATTATACT 
GGCCAGATAG TGCTCTACAG TGTTAATGAG AATGGCAATG TCACAGTTAT TCAGTCTCAC 
AGAGGTGACC AGATTGGCTC CTATTTTGGT AGTGTGCTGT GTGCAGTCGA TGTGAATAAG 
GACACCATTA CAGATGTGCT CTTGGTAGGT GCACCAATGT ACATGAATGA CCTAAAGAAA 
GAGGAAGGAA GAGTCTACCT GTTTACTATT ACAAAGGGCA TTTTGAATTG GCACCAATTT 
CTGGAAGGCC CCAAGGGTCT TGAAAATGCT CGATTTGGTT CAGCAATTGC AGCTCTTTCA 
GACATCAACA TGGATGGCTT TAATGACGTG ATTGTTGGTT CGCCTTTGGA AAATCAGAAC 
TCTGGAGCTG TGTACATCTA CAATGGTCAT GAGGGCATGA TTCGCTTGAG GTATTCTCAG 
AAAATCCTGG GGTCCGACAG AGCCTTTAGT AGCCACCTCC AGTACTTTGG GAGATCCCTG 
GATGGCTATG GAGATTTAAA TGGGGATTCC ATCACCGACG TGTCCGTGGG GGCCTTTGGA 
CAGGTCGTTC AGCTCTGGTC ACAGAGCATT GCTGATGTAT CTGTAGATGC TTCATTCACA 
CCAAAAAAAA TCACTTTGCT CAACAAAAAT GCTGAGATAA AACTTAAACT CTGCTTCAGT 
GCTAAGTTTA GACCTACTAA TCAAAACAAT CAAGTGGCCA TTGTGTATAA CATCACAATT 
GATGAAGACC AGTTTTCATC CAGAGTGATA TCCAGGGGGT TATTTAAGGA AAATAATGAA 
AGGTGCTTGC AGAAGACCAT GATAGTAAGT CAAGCACAGC GCTGTTCTGA GTACATCATC 
CACATACAGG AGCCCTCTGA CATTATCAGC CCTCTGAATC TGTGTATGAA CATTAGTCTG 
GAAAACCCTG GCACTAACCC TGCCCTTGAA GCCTACTCTG AGACGGTCAA GGTCTTCAGT 
ATCCCTTTCC ATAAAGACTG TGGTGATGAT GGAGTTTGCA TTTCTGATCT AGTTCTAAAT 
GTTCAGCAGC TGCCAGCCAC TCAACAACAG CCCTTCATTG TCAGCAACCA AAACAAAAGG 
TTAACATTTT CAGTACAACT GAAAAACAAG AAGGAAAGTG CCTACAACAC TGAGATTGTT 
GTTGATTTTT CAGAAAACCT GTTTTTTGCT TCCTGGTCCA TGCCGGTTGA TGGGACAGAA 
GTGACCTGCC AGATTGCTTC ATCTCAGAAG TCTGTTACCT GCAATGTGGG CTACCCTGCT 
TTAAAGAGCA AACAACAGGT GACTTTCACT ATTAACTTCG ACTTCAATCT TCAAAACCTT 
CAGAATCAGG CATCTATCAG TTTCCGAGCC TTAAGCGAAA GCCAGGAAGA AAACATGGCA 
GATAATTCAG TCAACTTAAA ACTCTCTCTG CTGTATGATG CCGAAATTCA CATAACAAGA 
TCTACCAACA TAAATTTTTA TGAAGTCTCC TTGGATGGGA ATGTTTCTTC TGTCGTGCAC 
AGTTTTGAAG ATATTGGTCC AAAATTCATC TTCTCCATTA AGGTAACAAC AGGAAGTGTT 
CCAGTAAGCA TGGCATCTGT GATCATCCAC ATCCCTCAAT ACACCAAAGA CAAGAACCCA 
CTGATGTACC TGACCGGGGT GCACACAGAT CAGGCTGGTG ACATCAGTTG CGAAGCCGAA 
ATAAATCCAC TGAAAATAGG ACAGACGTCT TCTTCTGTAT CTTTCAAGAG TGAAAATTTC 
CGGCACATAA AAGAATTGAA CTGTAGAACC GCTTCATGCA GTAACATCAT GTGCTGGCTG 
AGAGACCTTC AGGTGAAAGG AGAATACTTC CTTAATGTGT CCACCAGGAT TTGGAATGGG 
ACTTTCGCAG CATCGACTTT CCAGACAGTA CAGTTGACAG CAGCTGCAGA AATTGACACA 
TATAACCCTC AGATATACGT GATCGAAGAA AACACGGTGA CGATTCCCCT TACGATAATG 
AAACCCCATG AGAAAGTTGA AGTACCGACT GGAGTGATAG TAGGAAGTGT AATCGCTGGA 
ATCCTTTTGC TATTAGCTCT AGTTGCAATT TTATGGAAGC TTGGATTCTT CAAAAGAAAA 
TATGAAAAAA TGGCCAAAAA TCCAGATGAA ACCGATGAGA CCACAGAACT CAACAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

A mechanism to safeguard platelet adhesion under high shear flow: von Willebrand factor-glycoprotein Ib and integrin alphabeta-collagen interactions make complementary, collagen-type-specific contributions to adhesion.
Journal of thrombosis and haemostasis : JTH5(4)797-803(2007 Apr)
Moroi M,Jung SM

Matrix-specific suppression of integrin activation in shear stress signaling.
Molecular biology of the cell17(11)4686-97(2006 Nov)
Orr AW,Ginsberg MH,Shattil SJ,Deckmyn H,Schwartz MA

Identification of putative ligand binding sites within I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29)
The Journal of biological chemistry269(13)9659-63(1994 Apr)
Kamata T,Puzon W,Takada Y

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ITGA2 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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