FABP3 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	FABP3
Entrez Gene ID	281758
Full Name	fatty acid binding protein 3
Synonyms	FABP,FABP-3,H-FABP
General protein information	Preferred Names fatty acid binding protein 3 Names fatty acid-binding protein, heart MDGI fatty acid binding protein ( heart ) like heart fatty acid-binding protein heart-type fatty acid binding protein mammary-derived growth inhibitor
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174313.2	NP_776738.1	fatty acid-binding protein, heart

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	fabp3	NP_694493.1
Xenopus tropicalis (tropical clawed frog)	fabp3	NP_001015823.1
Canis lupus familiaris (dog)	FABP3	XP_005617722.1
Mus musculus (house mouse)	Fabp3	NP_034304.1
Gallus gallus (chicken)	FABP3	NP_001026060.1
Bos taurus (cattle)	FABP3	NP_776738.1
Homo sapiens (human)	FABP3	NP_004093.1
Pan troglodytes (chimpanzee)	FABP3	XP_003307987.1
Rattus norvegicus (Norway rat)	Fabp3	NP_077076.1

Gene Ontology
Bibliography

Related articles in PubMed

Tissue expression analysis, cloning and characterization of the 5'-regulatory region of the bovine FABP3 gene.
Li A, Wu L, Wang X, Xin Y, Zan L
Molecular biology reports43(9)991-8(2016 Sep)

Functional analysis of FABP3 in the milk fat synthesis signaling pathway of dairy cow mammary epithelial cells.
Liang MY, Hou XM, Qu B, Zhang N, Li N, Cui YJ, Li QZ, Gao XJ
In vitro cellular & developmental biology. Animal50(9)865-73(2014 Oct)

Investigation of the association of two candidate genes (H-FABP and PSMC1) with growth and carcass traits in Qinchuan beef cattle from China.
Liang W, Zhang HL, Liu Y, Lu BC, Liu X, Li Q, Cao Y
Genetics and molecular research : GMR13(1)1876-84(2014 Mar)

Association of polymorphisms in solute carrier family 27, isoform A6 (SLC27A6) and fatty acid-binding protein-3 and fatty acid-binding protein-4 (FABP3 and FABP4) with fatty acid composition of bovine milk.
Nafikov RA, Schoonmaker JP, Korn KT, Noack K, Garrick DJ, Koehler KJ, Minick-Bormann J, Reecy JM, Spurlock DE, Beitz DC
Journal of dairy science96(9)6007-21(2013 Sep)

FABP3, FABP4 and ANXA9 SNP genotypes in relation to breeding values for milk production traits in Polish Holstein-Friesian cows.
Kulig H, Kowalewska-Luczak I, Zukowski K, Kruszy?ski W
Genetika49(8)981-5(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sequence analysis showed that many transcriptional factor binding sites including TATA-box and CCAAT-box were present on the 5'-flanking region of bovine FABP3, and four CpG islands were found on nucleotides from -891 to +118.
Title: Tissue expression analysis, cloning and characterization of the 5'-regulatory region of the bovine FABP3 gene.

FABP3 has a role in milk fat synthesis signaling.
Title: Functional analysis of FABP3 in the milk fat synthesis signaling pathway of dairy cow mammary epithelial cells.

Thus, the results of our study suggest that the H-FABP and PSMC1 gene polymorphisms could be used as genetic markers in marker-assisted selection for improving Qinchuan beef cattle
Title: Investigation of the association of two candidate genes (H-FABP and PSMC1) with growth and carcass traits in Qinchuan beef cattle from China.

polymorphisms can be used to select for milk with lower concentrations of saturated fatty acids and higher concentrations of unsaturated fatty acids
Title: Association of polymorphisms in solute carrier family 27, isoform A6 (SLC27A6) and fatty acid-binding protein-3 and fatty acid-binding protein-4 (FABP3 and FABP4) with fatty acid composition of bovine milk.

FABP3 gene frequency and SNP genotypes in Holstein-Friesian cows and its relationship with protein and fat content in milk
Title: FABP3, FABP4 and ANXA9 SNP genotypes in relation to breeding values for milk production traits in Polish Holstein-Friesian cows.

The following FABP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FABP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa01452	NM_174313.2 Latest version!	Bos taurus fatty acid binding protein 3 (FABP3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FABP3 ( NM_174313.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776738.1 Bos taurus fatty acid binding protein 3 (FABP3), mRNA.

Price & Availability↑

CloneID	OBa01452
Clone ID Related Accession (Same CDS sequence)	NM_174313.2
Accession Version	NM_174313.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Bos taurus(cattle)
Product	fatty acid-binding protein, heart
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X12710.1. On Jun 3, 2003 this sequence version replaced NM_174313.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X12710.1, BC102153.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGGTGGACG CCTTCGTGGG TACCTGGAAG TTAGTGGACA GCAAGAATTT CGATGACTAC 
ATGAAGTCAC TCGGTGTCGG TTTTGCTACC AGGCAGGTGG GCAATATGAC CAAGCCTACC 
ACAATCATCG AAGTGAATGG GGACACAGTC ATCATAAAAA CACAAAGCAC CTTCAAGAAC 
ACAGAGATCA GCTTCAAGCT GGGAGTCGAG TTCGATGAGA CCACAGCAGA TGACAGGAAA 
GTCAAGTCCA TCGTGACGCT GGATGGCGGC AAACTTGTCC ACGTGCAGAA GTGGAATGGA 
CAAGAGACAT CACTTGTGCG GGAGATGGTT GACGGGAAAC TCATTCTGAC ACTCACCCAT 
GGCACTGCAG TTTGCACTCG TACTTACGAG AAACAGGCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776738.1
CDS	47..448
Translation	MVDAFVGTWKLVDSKNFDDYMKSLGVGFATRQVGNMTKPTTIIEVNGDTVIIKTQSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHVQKWNGQETSLVREMVDGKLILTLTHGTAVCTRTYEKQA

Target ORF information:

RefSeq Version	NM_174313.2
Organism	Bos taurus(cattle)
Definition	Bos taurus fatty acid binding protein 3 (FABP3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174313.2

ORF Insert Sequence:

ATGGTGGACG CCTTCGTGGG TACCTGGAAG TTAGTGGACA GCAAGAATTT CGATGACTAC 
ATGAAGTCAC TCGGTGTCGG TTTTGCTACC AGGCAGGTGG GCAATATGAC CAAGCCTACC 
ACAATCATCG AAGTGAATGG GGACACAGTC ATCATAAAAA CACAAAGCAC CTTCAAGAAC 
ACAGAGATCA GCTTCAAGCT GGGAGTCGAG TTCGATGAGA CCACAGCAGA TGACAGGAAA 
GTCAAGTCCA TCGTGACGCT GGATGGCGGC AAACTTGTCC ACGTGCAGAA GTGGAATGGA 
CAAGAGACAT CACTTGTGCG GGAGATGGTT GACGGGAAAC TCATTCTGAC ACTCACCCAT 
GGCACTGCAG TTTGCACTCG TACTTACGAG AAACAGGCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tissue expression analysis, cloning and characterization of the 5'-regulatory region of the bovine FABP3 gene.
Molecular biology reports43(9)991-8(2016 Sep)
Li A,Wu L,Wang X,Xin Y,Zan L

Functional analysis of FABP3 in the milk fat synthesis signaling pathway of dairy cow mammary epithelial cells.
In vitro cellular & developmental biology. Animal50(9)865-73(2014 Oct)
Liang MY,Hou XM,Qu B,Zhang N,Li N,Cui YJ,Li QZ,Gao XJ

Investigation of the association of two candidate genes (H-FABP and PSMC1) with growth and carcass traits in Qinchuan beef cattle from China.
Genetics and molecular research : GMR13(1)1876-84(2014 Mar)
Liang W,Zhang HL,Liu Y,Lu BC,Liu X,Li Q,Cao Y

Association of polymorphisms in solute carrier family 27, isoform A6 (SLC27A6) and fatty acid-binding protein-3 and fatty acid-binding protein-4 (FABP3 and FABP4) with fatty acid composition of bovine milk.
Journal of dairy science96(9)6007-21(2013 Sep)
Nafikov RA,Schoonmaker JP,Korn KT,Noack K,Garrick DJ,Koehler KJ,Minick-Bormann J,Reecy JM,Spurlock DE,Beitz DC

FABP3, FABP4 and ANXA9 SNP genotypes in relation to breeding values for milk production traits in Polish Holstein-Friesian cows.
Genetika49(8)981-5(2013 Aug)
Kulig H,Kowalewska-Luczak I,Zukowski K,Kruszy?ski W

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FABP3 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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