Gene Symbol | CYP19A1 |
Entrez Gene ID | 281740 |
Full Name | cytochrome P450, family 19, subfamily A, polypeptide 1 |
Synonyms | CYP19,CYP19P1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
ORF » Species Summary » Bos taurus » CYP19A1 cDNA ORF clone
Gene Symbol | CYP19A1 |
Entrez Gene ID | 281740 |
Full Name | cytochrome P450, family 19, subfamily A, polypeptide 1 |
Synonyms | CYP19,CYP19P1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_010809326.2 | XP_010807628.1 | aromatase isoform X1 |
NM_174305.1 | NP_776730.1 | aromatase |
Homo sapiens (human) | CYP19A1 | NP_112503.1 |
Canis lupus familiaris (dog) | CYP19A1 | NP_001008715.1 |
Mus musculus (house mouse) | Cyp19a1 | NP_031836.1 |
Rattus norvegicus (Norway rat) | Cyp19a1 | NP_058781.2 |
Danio rerio (zebrafish) | cyp19a1b | NP_571717.1 |
Danio rerio (zebrafish) | cyp19a1a | NP_571229.2 |
Pan troglodytes (chimpanzee) | CYP19A1 | XP_001169497.1 |
Gallus gallus (chicken) | CYP19A1 | NP_001001761.1 |
CYP19A1 | XP_001082665.2 | |
Bos taurus (cattle) | CYP19A1 | NP_776730.1 |
Xenopus tropicalis (tropical clawed frog) | cyp19a1 | NP_001090630.1 |
Evaluation of coding-independent functions of the transcribed bovine aromatase pseudogene CYP19P1.
Chwalisz M, F?rbass R
BMC research notes7378(2014 Jun)
Factors regulating the bovine, caprine, rat and human ovarian aromatase promoters in a bovine granulosa cell model.
Sahmi F, Nicola ES, Zamberlam GO, Gon?alves PD, Vanselow J, Price CA
General and comparative endocrinology20010-7(2014 May)
Bovine large luteal cells show increasing de novo DNA methylation of the main ovarian CYP19A1 promoter P2.
Spitschak M, Vanselow J
General and comparative endocrinology178(1)37-45(2012 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
in granulosa cells of dominant follicles the concentration of CYP19P1 mRNA was very low compared to CYP19A1 mRNA. CONCLUSIONS: CYP19P1 and CYP19A1 transcripts might interfere in placental cotyledons
Title: Evaluation of coding-independent functions of the transcribed bovine aromatase pseudogene CYP19P1.
These data suggest that a major reason why CYP19A1 is not expressed in luteinized cells (and the corpus luteum) of ruminants may be the stimulatory effect of FOXL2, which does not appear to be the case in the human and rat.
Title: Factors regulating the bovine, caprine, rat and human ovarian aromatase promoters in a bovine granulosa cell model.
Data indicated de novo DNA methylation fter the luteinizing hormone-induced down-regulation of CYP19A1 expression, suggesting that DNA methylation might play a role for permanent silencing of previously down-regulated genes.
Title: Bovine large luteal cells show increasing de novo DNA methylation of the main ovarian CYP19A1 promoter P2.
This study evaluated the relationships among aromatase, IGF-1, IGF2R, and FSH levels expressed in ovarian follicles of cattle selected for twin pregnancies.
Title: Increased abundance of aromatase and follicle stimulating hormone receptor mRNA and decreased insulin-like growth factor-2 receptor mRNA in small ovarian follicles of cattle selected for twin births.
P450(AROM) is localized in the cytoplasm and only seldom present in the fine extensions of the cells in frontal cortex.
Title: Expression and localization of aromatase P450AROM, estrogen receptor-?, and estrogen receptor-? in the developing fetal bovine frontal cortex.
The following CYP19A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP19A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa42609 | |
Clone ID Related Accession (Same CDS sequence) | NM_174305.1 | |
Accession Version | NM_174305.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Bos taurus(cattle) | |
Product | aromatase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z32741.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Z32741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145433, SAMN03145439 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCTTTTGG AAGTGCTGAA CCCAAGGCAT TACAACGTCA CCAGCATGGT GTCCGAAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776730.1 |
CDS | 183..1694 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174305.1 |
1 | ATGCTTTTGG AAGTGCTGAA CCCAAGGCAT TACAACGTCA CCAGCATGGT GTCCGAAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa45213 | |
Clone ID Related Accession (Same CDS sequence) | XM_010809326.2 | |
Accession Version | XM_010809326.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | aromatase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104282.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010809326.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTTTTGG AAGTGCTGAA CCCAAGGCAT TACAACGTCA CCAGCATGGT GTCCGAAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_010807628.1 |
CDS | 362..1873 |
Translation |
Target ORF information:
Target ORF information:
|
XM_010809326.2 |
1 | ATGCTTTTGG AAGTGCTGAA CCCAAGGCAT TACAACGTCA CCAGCATGGT GTCCGAAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Evaluation of coding-independent functions of the transcribed bovine aromatase pseudogene CYP19P1. |
Factors regulating the bovine, caprine, rat and human ovarian aromatase promoters in a bovine granulosa cell model. |
Bovine large luteal cells show increasing de novo DNA methylation of the main ovarian CYP19A1 promoter P2. |