CYP17A1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP17A1
Entrez Gene ID	281739
Full Name	cytochrome P450, family 17, subfamily A, polypeptide 1
Synonyms	CYP17,CYPXVII,P450-C17,P450c17
Gene Type	protein-coding
Organism	Bos taurus(cattle)
Genome	Chromosome: 26 Map Location: 26q22-q31

mRNA and Protein(s)

mRNA	Protein	Name
XM_024985465.1	XP_024841233.1	steroid 17-alpha-hydroxylase/17,20 lyase isoform X1
XM_024985466.1	XP_024841234.1	steroid 17-alpha-hydroxylase/17,20 lyase isoform X2
NM_174304.2	NP_776729.1	steroid 17-alpha-hydroxylase/17,20 lyase precursor

Pathways from BioSystems

Homologies

	CYP17A1	NP_001035322.1
Arabidopsis thaliana (thale cress)	CYP706A3	NP_199275.1
Canis lupus familiaris (dog)	CYP17A1	XP_535000.3
Arabidopsis thaliana (thale cress)	CYP706A4	NP_192967.1
Arabidopsis thaliana (thale cress)	CYP706A2	NP_194002.1
Homo sapiens (human)	CYP17A1	NP_000093.1
Bos taurus (cattle)	CYP17A1	NP_776729.1
Arabidopsis thaliana (thale cress)	CYP706A6	NP_192969.4
Arabidopsis thaliana (thale cress)	CYP706A5	NP_192968.3
Arabidopsis thaliana (thale cress)	CYP706A1	NP_567665.2
Mus musculus (house mouse)	Cyp17a1	NP_031835.3
Oryza sativa (rice)	Os08g0547900	NP_001062431.2
Pan troglodytes (chimpanzee)	CYP17A1	NP_001009052.1
Rattus norvegicus (Norway rat)	Cyp17a1	NP_036885.1
Arabidopsis thaliana (thale cress)	CYP706A7	NP_192970.1
Oryza sativa (rice)	Os01g0700500	NP_001043985.2

Gene Ontology
Bibliography

Related articles in PubMed

Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.
Glister C, Satchell L, Bathgate RA, Wade JD, Dai Y, Ivell R, Anand-Ivell R, Rodgers RJ, Knight PG
Proceedings of the National Academy of Sciences of the United States of America110(15)E1426-35(2013 Apr)

A false single nucleotide polymorphism generated by gene duplication compromises meat traceability.
Sanz A, Ordov?s L, Zaragoza P, Sanz A, de Blas I, Rodellar C
Meat science91(3)347-51(2012 Jul)

Luteinizing hormone (LH) regulates production of androstenedione and progesterone via control of histone acetylation of StAR and CYP17 promoters in ovarian theca cells.
Murayama C, Miyazaki H, Miyamoto A, Shimizu T
Molecular and cellular endocrinology350(1)1-9(2012 Mar)

Comparison of cAMP-responsive DNA sequences and their binding proteins associated with expression of the bovine CYP17 and CYP11A and human CYP21B genes.
Waterman MR, Kagawa N, Zanger UM, Momoi K, Lund J, Simpson ER
The Journal of steroid biochemistry and molecular biology43(8)931-5(1992 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

BMP6 has a role in downregulating INSL3 and CYP17A1 and other proteins that modulate ovarian androgen production
Title: Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.

By alignment analysis and sequencing, we detected that the g.329C>T SNP is a false positive polymorphism, which allows us to explain the inflated heterozygotic value.
Title: A false single nucleotide polymorphism generated by gene duplication compromises meat traceability.

The binding of SF-1 to the CYP17 and StAR promoter regions increased in theca cells incubated with low levels of luteinizing hormone.
Title: Luteinizing hormone (LH) regulates production of androstenedione and progesterone via control of histone acetylation of StAR and CYP17 promoters in ovarian theca cells.

the bovine genome contains three paralogous copies of the CYP17A1 gene, of which two (CYP17A1b and CYP17A1x) might be silenced by epigenetic modification (promoter methylation).
Title: The bovine genome contains three differentially methylated paralogous copies of the P450c17 encoding gene (CYP17A1).

Data suggest that the upstream region of gene encoding CYP17 contains unique cAMP-responsive sequence and appears to bind unique nuclear proteins or transcription factors in adrenal cortex. [REVIEW]
Title: Comparison of cAMP-responsive DNA sequences and their binding proteins associated with expression of the bovine CYP17 and CYP11A and human CYP21B genes.

The following CYP17A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP17A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa00816	NM_174304.2 Latest version!	Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OBa61874	XM_024985465.1 Latest version!	Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00
OBa61875	XM_024985466.1 Latest version!	Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP17A1 ( NM_174304.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776729.1 Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), mRNA.

Price & Availability↑

CloneID	OBa00816
Clone ID Related Accession (Same CDS sequence)	NM_174304.2
Accession Version	NM_174304.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Bos taurus(cattle)
Product	steroid 17-alpha-hydroxylase/17,20 lyase precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M12547.1. On Feb 21, 2013 this sequence version replaced NM_174304.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M12547.1, BC110169.1 [ECO:0000332] ##Evidence-Data-END##

ATGTGGCTGC TCCTGGCTGT CTTTCTGCTC ACCCTCGCCT ATTTATTTTG GCCCAAGACC 
AAGCACTCTG GTGCCAAGTA CCCCAGGAGC CTCCCATCCC TGCCCCTGGT GGGCAGCCTG 
CCGTTCCTCC CCAGACGTGG CCAGCAGCAC AAGAACTTCT TCAAGCTGCA GGAAAAATAT 
GGCCCCATCT ATTCCTTTCG TTTGGGTTCC AAGACGACTG TGATGATTGG ACACCACCAG 
TTGGCCAGGG AGGTGCTTCT CAAGAAGGGC AAGGAATTCT CTGGGCGTCC CAAAGTGGCC 
ACTCTAGACA TCCTGTCAGA CAACCAAAAG GGCATTGCCT TTGCCGACCA TGGTGCCCAC 
TGGCAGCTGC ATCGGAAGCT GGCACTGAAT GCCTTTGCCC TGTTCAAGGA TGGCAACCTG 
AAGTTAGAGA AGATCATTAA TCAGGAAGCC AATGTGCTCT GTGATTTCCT GGCCACCCAG 
CATGGAGAGG CCATAGATCT GTCCGAGCCT CTCTCTCTGG CGGTGACCAA CATAATCAGC 
TTTATCTGCT TCAACTTCTC CTTCAAGAAT GAGGATCCTG CCCTGAAGGC CATACAAAAT 
GTCAATGATG GCATCCTGGA GGTTCTGAGC AAGGAAGTTC TGTTAGACAT ATTCCCTGTG 
CTGAAGATTT TCCCCAGCAA AGCCATGGAA AAGATGAAGG GTTGTGTTCA AACGCGAAAT 
GAATTGCTGA ATGAAATCCT TGAAAAATGT CAGGAGAACT TCAGCAGTGA TTCCATCACT 
AACTTGCTGC ACATACTGAT CCAAGCCAAG GTGAATGCAG ACAATAACAA TGCTGGCCCA 
GACCAGGATT CAAAGCTGCT TTCAAATAGA CACATGCTCG CTACTATAGG GGACATCTTC 
GGGGCTGGTG TGGAGACCAC CACGTCTGTG ATAAAGTGGA TCGTGGCCTA CCTGCTACAC 
CATCCTTCGT TGAAGAAGAG GATCCAGGAT GACATTGACC AGATTATAGG TTTCAATCGC 
ACCCCAACCA TCAGTGACCG GAACCGCCTT GTCCTGCTGG AGGCGACCAT CAGAGAAGTG 
CTCCGAATCC GGCCTGTGGC CCCTACGCTG ATCCCCCACA AGGCTGTCAT TGACTCCAGC 
ATTGGCGACC TTACCATTGA CAAAGGCACA GACGTTGTGG TCAACCTGTG GGCACTGCAT 
CACAGTGAGA AGGAGTGGCA GCATCCCGAC CTGTTCATGC CCGAGCGCTT CTTGGACCCC 
ACGGGGACGC AACTCATCTC GCCATCATTA AGCTACTTGC CCTTTGGAGC AGGACCCCGC 
TCCTGCGTAG GTGAGATGCT AGCCCGCCAG GAGCTCTTCC TCTTCATGTC CCGGCTGCTG 
CAGAGGTTCA ACCTGGAGAT CCCGGATGAT GGGAAGCTAC CTTCTCTGGA GGGCCATGCC 
AGTCTCGTCT TGCAGATCAA ACCTTTCAAG GTGAAGATCG AGGTGCGCCA GGCCTGGAAG 
GAAGCCCAGG CTGAGGGTAG CACCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776729.1
CDS	47..1576
Translation	MWLLLAVFLLTLAYLFWPKTKHSGAKYPRSLPSLPLVGSLPFLPRRGQQHKNFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKVATLDILSDNQKGIAFADHGAHWQLHRKLALNAFALFKDGNLKLEKIINQEANVLCDFLATQHGEAIDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQNVNDGILEVLSKEVLLDIFPVLKIFPSKAMEKMKGCVQTRNELLNEILEKCQENFSSDSITNLLHILIQAKVNADNNNAGPDQDSKLLSNRHMLATIGDIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKEWQHPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDGKLPSLEGHASLVLQIKPFKVKIEVRQAWKEAQAEGSTP

Target ORF information:

RefSeq Version	NM_174304.2
Organism	Bos taurus(cattle)
Definition	Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174304.2

ORF Insert Sequence:

ATGTGGCTGC TCCTGGCTGT CTTTCTGCTC ACCCTCGCCT ATTTATTTTG GCCCAAGACC 
AAGCACTCTG GTGCCAAGTA CCCCAGGAGC CTCCCATCCC TGCCCCTGGT GGGCAGCCTG 
CCGTTCCTCC CCAGACGTGG CCAGCAGCAC AAGAACTTCT TCAAGCTGCA GGAAAAATAT 
GGCCCCATCT ATTCCTTTCG TTTGGGTTCC AAGACGACTG TGATGATTGG ACACCACCAG 
TTGGCCAGGG AGGTGCTTCT CAAGAAGGGC AAGGAATTCT CTGGGCGTCC CAAAGTGGCC 
ACTCTAGACA TCCTGTCAGA CAACCAAAAG GGCATTGCCT TTGCCGACCA TGGTGCCCAC 
TGGCAGCTGC ATCGGAAGCT GGCACTGAAT GCCTTTGCCC TGTTCAAGGA TGGCAACCTG 
AAGTTAGAGA AGATCATTAA TCAGGAAGCC AATGTGCTCT GTGATTTCCT GGCCACCCAG 
CATGGAGAGG CCATAGATCT GTCCGAGCCT CTCTCTCTGG CGGTGACCAA CATAATCAGC 
TTTATCTGCT TCAACTTCTC CTTCAAGAAT GAGGATCCTG CCCTGAAGGC CATACAAAAT 
GTCAATGATG GCATCCTGGA GGTTCTGAGC AAGGAAGTTC TGTTAGACAT ATTCCCTGTG 
CTGAAGATTT TCCCCAGCAA AGCCATGGAA AAGATGAAGG GTTGTGTTCA AACGCGAAAT 
GAATTGCTGA ATGAAATCCT TGAAAAATGT CAGGAGAACT TCAGCAGTGA TTCCATCACT 
AACTTGCTGC ACATACTGAT CCAAGCCAAG GTGAATGCAG ACAATAACAA TGCTGGCCCA 
GACCAGGATT CAAAGCTGCT TTCAAATAGA CACATGCTCG CTACTATAGG GGACATCTTC 
GGGGCTGGTG TGGAGACCAC CACGTCTGTG ATAAAGTGGA TCGTGGCCTA CCTGCTACAC 
CATCCTTCGT TGAAGAAGAG GATCCAGGAT GACATTGACC AGATTATAGG TTTCAATCGC 
ACCCCAACCA TCAGTGACCG GAACCGCCTT GTCCTGCTGG AGGCGACCAT CAGAGAAGTG 
CTCCGAATCC GGCCTGTGGC CCCTACGCTG ATCCCCCACA AGGCTGTCAT TGACTCCAGC 
ATTGGCGACC TTACCATTGA CAAAGGCACA GACGTTGTGG TCAACCTGTG GGCACTGCAT 
CACAGTGAGA AGGAGTGGCA GCATCCCGAC CTGTTCATGC CCGAGCGCTT CTTGGACCCC 
ACGGGGACGC AACTCATCTC GCCATCATTA AGCTACTTGC CCTTTGGAGC AGGACCCCGC 
TCCTGCGTAG GTGAGATGCT AGCCCGCCAG GAGCTCTTCC TCTTCATGTC CCGGCTGCTG 
CAGAGGTTCA ACCTGGAGAT CCCGGATGAT GGGAAGCTAC CTTCTCTGGA GGGCCATGCC 
AGTCTCGTCT TGCAGATCAA ACCTTTCAAG GTGAAGATCG AGGTGCGCCA GGCCTGGAAG 
GAAGCCCAGG CTGAGGGTAG CACCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP17A1 ( XM_024985465.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024841233.1 Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa61874
Clone ID Related Accession (Same CDS sequence)	XM_024985465.1
Accession Version	XM_024985465.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	steroid 17-alpha-hydroxylase/17,20 lyase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037353.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTGC TCCTGGCTGT CTTTCTGCTC ACCCTCGCCT ATTTATTTTG GCCCAAGACC 
AAGCACTCTG GTGCCAAGTA CCCCAGGAGC CTCCCATCCC TGCCCCTGGT GGGCAGCCTG 
CCGTTCCTCC CCAGACGTGG CCAGCAGCAC AAGAACTTCT TCAAGCTGCA GGAAAAATAT 
GGCCCCATCT ATTCCTTTCG TTTGGGTTCC AAGACGACTG TGATGATTGG ACACCACCAG 
TTGGCCAGGG AGGTGCTTCT CAAGAAGGGC AAGGAATTCT CTGGGCGTCC CAAAGTGGCC 
ACTCTAGACA TCCTGTCAGA CAACCAAAAG GGCATTGCCT TTGCCGACCA TGGTGCCCAC 
TGGCAGCTGC ATCGGAAGCT GGCACTGAAT GCCTTTGCCC TGTTCAAGGA TGGCAACCTG 
AAGTTAGAGA AGATCATTAA TCAGGAAGCC AATGTGCTCT GTGATTTCCT GGCCACCCAG 
CATGGAGAGG CCATAGATCT GTCCGAGCCT CTCTCTCTGG CGGTGACCAA CATAATCAGC 
TTTATCTGCT TCAACTTCTC CTTCAAGAAT GAGGATCCTG CCCTGAAGGC CATACAAAAT 
GTCAATGATG GCATCCTGGA GGTTCTGAGC AAGGAAGTTC TGTTAGACAT ATTCCCTGTG 
CTGAAGATTT TCCCCAGCAA AGCCATGGAA AAGATGAAGG GTTGTGTTCA AATGCGAAAT 
GAATTGCTGA ATGAAATCCT TGAAAAATGT CAGGAGAACT TCAGCAGTGA TTCCATCACT 
AACTTGCTGC ACATACTGAT CCAAGCCAAG GTGAATGCAG ACAATAACAA TGCTGGCCCA 
GACCAGGATT CAAAGCTGCT TTCAAATAGA CACATGCTTG CTACCATAGG GGACATCTTC 
GGGGCTGGTG TAGAGACCAC CACGTCTGTG ATAAAGTGGA TCGTGGCCTA CCTGCTACAC 
CATCCTTCAT TGAAGAAGAG GATCCAGGAT GACATTGACC AGATTATAGG TTTCAATCGC 
ACCCCAACCA TCAGTGACCG GAACCGCCTT GTCCTGCTGG AGGCGACCAT CAGAGAAGTG 
CTCCGAATCC GGCCTGTGGC CCCTACGCTG ATCCCCCACA AGGCTGTCAT TGACTCCAGC 
ATTGGCGACC TTACCATTGA CAAAGGCACA GACGTTGTGG TCAACCTGTG GGCACTGCAT 
CACAGTGAGA AGGAGTGGCA GCATCCCGAC CTGTTCATGC CCGGACCCCG CTCCTGCGTA 
GGTGAGATGC TAGCCCGCCA GGAGCTCTTC CTCTTCATGT CCTGGCTGCT GCAGAGGTTC 
AACCTGGAGA TCCCGGATGA TGGGAAGCTA CCCTCTCTGG AGGGCCATGC CAGTCTCGTC 
TTGCAGATCA AACCTTTCAA GGTGAAGATC GAGGTGCGCC AGGCCTGGAA GGAAGCCCAG 
GCTGAGGGTA GCACCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024841233.1
CDS	179..1639
Translation	MWLLLAVFLLTLAYLFWPKTKHSGAKYPRSLPSLPLVGSLPFLPRRGQQHKNFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKVATLDILSDNQKGIAFADHGAHWQLHRKLALNAFALFKDGNLKLEKIINQEANVLCDFLATQHGEAIDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQNVNDGILEVLSKEVLLDIFPVLKIFPSKAMEKMKGCVQMRNELLNEILEKCQENFSSDSITNLLHILIQAKVNADNNNAGPDQDSKLLSNRHMLATIGDIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKEWQHPDLFMPGPRSCVGEMLARQELFLFMSWLLQRFNLEIPDDGKLPSLEGHASLVLQIKPFKVKIEVRQAWKEAQAEGSTS

Target ORF information:

RefSeq Version	XM_024985465.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024985465.1

ORF Insert Sequence:

ATGTGGCTGC TCCTGGCTGT CTTTCTGCTC ACCCTCGCCT ATTTATTTTG GCCCAAGACC 
AAGCACTCTG GTGCCAAGTA CCCCAGGAGC CTCCCATCCC TGCCCCTGGT GGGCAGCCTG 
CCGTTCCTCC CCAGACGTGG CCAGCAGCAC AAGAACTTCT TCAAGCTGCA GGAAAAATAT 
GGCCCCATCT ATTCCTTTCG TTTGGGTTCC AAGACGACTG TGATGATTGG ACACCACCAG 
TTGGCCAGGG AGGTGCTTCT CAAGAAGGGC AAGGAATTCT CTGGGCGTCC CAAAGTGGCC 
ACTCTAGACA TCCTGTCAGA CAACCAAAAG GGCATTGCCT TTGCCGACCA TGGTGCCCAC 
TGGCAGCTGC ATCGGAAGCT GGCACTGAAT GCCTTTGCCC TGTTCAAGGA TGGCAACCTG 
AAGTTAGAGA AGATCATTAA TCAGGAAGCC AATGTGCTCT GTGATTTCCT GGCCACCCAG 
CATGGAGAGG CCATAGATCT GTCCGAGCCT CTCTCTCTGG CGGTGACCAA CATAATCAGC 
TTTATCTGCT TCAACTTCTC CTTCAAGAAT GAGGATCCTG CCCTGAAGGC CATACAAAAT 
GTCAATGATG GCATCCTGGA GGTTCTGAGC AAGGAAGTTC TGTTAGACAT ATTCCCTGTG 
CTGAAGATTT TCCCCAGCAA AGCCATGGAA AAGATGAAGG GTTGTGTTCA AATGCGAAAT 
GAATTGCTGA ATGAAATCCT TGAAAAATGT CAGGAGAACT TCAGCAGTGA TTCCATCACT 
AACTTGCTGC ACATACTGAT CCAAGCCAAG GTGAATGCAG ACAATAACAA TGCTGGCCCA 
GACCAGGATT CAAAGCTGCT TTCAAATAGA CACATGCTTG CTACCATAGG GGACATCTTC 
GGGGCTGGTG TAGAGACCAC CACGTCTGTG ATAAAGTGGA TCGTGGCCTA CCTGCTACAC 
CATCCTTCAT TGAAGAAGAG GATCCAGGAT GACATTGACC AGATTATAGG TTTCAATCGC 
ACCCCAACCA TCAGTGACCG GAACCGCCTT GTCCTGCTGG AGGCGACCAT CAGAGAAGTG 
CTCCGAATCC GGCCTGTGGC CCCTACGCTG ATCCCCCACA AGGCTGTCAT TGACTCCAGC 
ATTGGCGACC TTACCATTGA CAAAGGCACA GACGTTGTGG TCAACCTGTG GGCACTGCAT 
CACAGTGAGA AGGAGTGGCA GCATCCCGAC CTGTTCATGC CCGGACCCCG CTCCTGCGTA 
GGTGAGATGC TAGCCCGCCA GGAGCTCTTC CTCTTCATGT CCTGGCTGCT GCAGAGGTTC 
AACCTGGAGA TCCCGGATGA TGGGAAGCTA CCCTCTCTGG AGGGCCATGC CAGTCTCGTC 
TTGCAGATCA AACCTTTCAA GGTGAAGATC GAGGTGCGCC AGGCCTGGAA GGAAGCCCAG 
GCTGAGGGTA GCACCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP17A1 ( XM_024985466.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024841234.1 Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa61875
Clone ID Related Accession (Same CDS sequence)	XM_024985466.1
Accession Version	XM_024985466.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	steroid 17-alpha-hydroxylase/17,20 lyase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037353.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTGC TCCTGGCTGT CTTTCTGCTC ACCCTCGCCT ATTTATTTTG GCCCAAGACC 
AAGCACTCTG GTGCCAAGTA CCCCAGGAGC CTCCCATCCC TGCCCCTGGT GGGCAGCCTG 
CCGTTCCTCC CCAGACGTGG CCAGCAGCAC AAGAACTTCT TCAAGCTGCA GGAAAAATAT 
GGCCCCATCT ATTCCTTTCG TTTGGGTTCC AAGACGACTG TGATGATTGG ACACCACCAG 
TTGGCCAGGG AGGTGCTTCT CAAGAAGGGC AAGGAATTCT CTGGGCGTCC CAAAGTGGCC 
ACTCTAGACA TCCTGTCAGA CAACCAAAAG GGCATTGCCT TTGCCGACCA TGGTGCCCAC 
TGGCAGCTGC ATCGGAAGCT GGCACTGAAT GCCTTTGCCC TGTTCAAGGA TGGCAACCTG 
AAGTTAGAGA AGATCATTAA TCAGGAAGCC AATGTGCTCT GTGATTTCCT GGCCACCCAG 
CATGGAGAGG CCATAGATCT GTCCGAGCCT CTCTCTCTGG CGGTGACCAA CATAATCAGC 
TTTATCTGCT TCAACTTCTC CTTCAAGAAT GAGGATCCTG CCCTGAAGGC CATACAAAAT 
GTCAATGATG GCATCCTGGA GGTTCTGAGC AAGGAAGTTC TGTTAGACAT ATTCCCTGTG 
CTGAAGGAGA ACTTCAGCAG TGATTCCATC ACTAACTTGC TGCACATACT GATCCAAGCC 
AAGGTGAATG CAGACAATAA CAATGCTGGC CCAGACCAGG ATTCAAAGCT GCTTTCAAAT 
AGACACATGC TTGCTACCAT AGGGGACATC TTCGGGGCTG GTGTAGAGAC CACCACGTCT 
GTGATAAAGT GGATCGTGGC CTACCTGCTA CACCATCCTT CATTGAAGAA GAGGATCCAG 
GATGACATTG ACCAGATTAT AGGTTTCAAT CGCACCCCAA CCATCAGTGA CCGGAACCGC 
CTTGTCCTGC TGGAGGCGAC CATCAGAGAA GTGCTCCGAA TCCGGCCTGT GGCCCCTACG 
CTGATCCCCC ACAAGGCTGT CATTGACTCC AGCATTGGCG ACCTTACCAT TGACAAAGGC 
ACAGACGTTG TGGTCAACCT GTGGGCACTG CATCACAGTG AGAAGGAGTG GCAGCATCCC 
GACCTGTTCA TGCCCGAGCG CTTCTTGGAC CCCACGGGGG CGCAACTCAT CTCGCCATCG 
TTAAGCTACT TGCCCTTTGG AGCAGGACCC CGCTCCTGCG TAGGTGAGAT GCTAGCCCGC 
CAGGAGCTCT TCCTCTTCAT GTCCTGGCTG CTGCAGAGGT TCAACCTGGA GATCCCGGAT 
GATGGGAAGC TACCCTCTCT GGAGGGCCAT GCCAGTCTCG TCTTGCAGAT CAAACCTTTC 
AAGGTGAAGA TCGAGGTGCG CCAGGCCTGG AAGGAAGCCC AGGCTGAGGG TAGCACCTCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024841234.1
CDS	184..1626
Translation	MWLLLAVFLLTLAYLFWPKTKHSGAKYPRSLPSLPLVGSLPFLPRRGQQHKNFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKVATLDILSDNQKGIAFADHGAHWQLHRKLALNAFALFKDGNLKLEKIINQEANVLCDFLATQHGEAIDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQNVNDGILEVLSKEVLLDIFPVLKENFSSDSITNLLHILIQAKVNADNNNAGPDQDSKLLSNRHMLATIGDIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKEWQHPDLFMPERFLDPTGAQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSWLLQRFNLEIPDDGKLPSLEGHASLVLQIKPFKVKIEVRQAWKEAQAEGSTS

Target ORF information:

RefSeq Version	XM_024985466.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024985466.1

ORF Insert Sequence:

ATGTGGCTGC TCCTGGCTGT CTTTCTGCTC ACCCTCGCCT ATTTATTTTG GCCCAAGACC 
AAGCACTCTG GTGCCAAGTA CCCCAGGAGC CTCCCATCCC TGCCCCTGGT GGGCAGCCTG 
CCGTTCCTCC CCAGACGTGG CCAGCAGCAC AAGAACTTCT TCAAGCTGCA GGAAAAATAT 
GGCCCCATCT ATTCCTTTCG TTTGGGTTCC AAGACGACTG TGATGATTGG ACACCACCAG 
TTGGCCAGGG AGGTGCTTCT CAAGAAGGGC AAGGAATTCT CTGGGCGTCC CAAAGTGGCC 
ACTCTAGACA TCCTGTCAGA CAACCAAAAG GGCATTGCCT TTGCCGACCA TGGTGCCCAC 
TGGCAGCTGC ATCGGAAGCT GGCACTGAAT GCCTTTGCCC TGTTCAAGGA TGGCAACCTG 
AAGTTAGAGA AGATCATTAA TCAGGAAGCC AATGTGCTCT GTGATTTCCT GGCCACCCAG 
CATGGAGAGG CCATAGATCT GTCCGAGCCT CTCTCTCTGG CGGTGACCAA CATAATCAGC 
TTTATCTGCT TCAACTTCTC CTTCAAGAAT GAGGATCCTG CCCTGAAGGC CATACAAAAT 
GTCAATGATG GCATCCTGGA GGTTCTGAGC AAGGAAGTTC TGTTAGACAT ATTCCCTGTG 
CTGAAGGAGA ACTTCAGCAG TGATTCCATC ACTAACTTGC TGCACATACT GATCCAAGCC 
AAGGTGAATG CAGACAATAA CAATGCTGGC CCAGACCAGG ATTCAAAGCT GCTTTCAAAT 
AGACACATGC TTGCTACCAT AGGGGACATC TTCGGGGCTG GTGTAGAGAC CACCACGTCT 
GTGATAAAGT GGATCGTGGC CTACCTGCTA CACCATCCTT CATTGAAGAA GAGGATCCAG 
GATGACATTG ACCAGATTAT AGGTTTCAAT CGCACCCCAA CCATCAGTGA CCGGAACCGC 
CTTGTCCTGC TGGAGGCGAC CATCAGAGAA GTGCTCCGAA TCCGGCCTGT GGCCCCTACG 
CTGATCCCCC ACAAGGCTGT CATTGACTCC AGCATTGGCG ACCTTACCAT TGACAAAGGC 
ACAGACGTTG TGGTCAACCT GTGGGCACTG CATCACAGTG AGAAGGAGTG GCAGCATCCC 
GACCTGTTCA TGCCCGAGCG CTTCTTGGAC CCCACGGGGG CGCAACTCAT CTCGCCATCG 
TTAAGCTACT TGCCCTTTGG AGCAGGACCC CGCTCCTGCG TAGGTGAGAT GCTAGCCCGC 
CAGGAGCTCT TCCTCTTCAT GTCCTGGCTG CTGCAGAGGT TCAACCTGGA GATCCCGGAT 
GATGGGAAGC TACCCTCTCT GGAGGGCCAT GCCAGTCTCG TCTTGCAGAT CAAACCTTTC 
AAGGTGAAGA TCGAGGTGCG CCAGGCCTGG AAGGAAGCCC AGGCTGAGGG TAGCACCTCA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.
Proceedings of the National Academy of Sciences of the United States of America110(15)E1426-35(2013 Apr)
Glister C,Satchell L,Bathgate RA,Wade JD,Dai Y,Ivell R,Anand-Ivell R,Rodgers RJ,Knight PG

A false single nucleotide polymorphism generated by gene duplication compromises meat traceability.
Meat science91(3)347-51(2012 Jul)
Sanz A,Ordov?s L,Zaragoza P,Sanz A,de Blas I,Rodellar C

Luteinizing hormone (LH) regulates production of androstenedione and progesterone via control of histone acetylation of StAR and CYP17 promoters in ovarian theca cells.
Molecular and cellular endocrinology350(1)1-9(2012 Mar)
Murayama C,Miyazaki H,Miyamoto A,Shimizu T

Comparison of cAMP-responsive DNA sequences and their binding proteins associated with expression of the bovine CYP17 and CYP11A and human CYP21B genes.
The Journal of steroid biochemistry and molecular biology43(8)931-5(1992 Dec)
Waterman MR,Kagawa N,Zanger UM,Momoi K,Lund J,Simpson ER

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

CYP17A1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報