Gene Symbol | GZMB |
Entrez Gene ID | 281731 |
Full Name | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
Synonyms | BDMD1,CTLA1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » GZMB cDNA ORF clone
Gene Symbol | GZMB |
Entrez Gene ID | 281731 |
Full Name | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
Synonyms | BDMD1,CTLA1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174296.2 | NP_776721.1 | duodenase-1 precursor |
Expression profiles of perforin, granzyme B and granulysin genes during the estrous cycle and gestation in the bovine endometrium.
Ohta T, Koshi K, Ushizawa K, Hosoe M, Takahashi T, Yamaguchi T, Kizaki K, Hashizume K
Animal science journal = Nihon chikusan Gakkaiho85(7)763-9(2014 Jul)
Effect of reactive center loop structure of antichymotrypsin on inhibition of duodenase activity.
Zamolodchikova TS, Popykina NA, Gladysheva IP, Larionova NI
Biochemistry. Biokhimiia74(8)824-33(2009 Aug)
Crystal structure of bovine duodenase, a serine protease, with dual trypsin and chymotrypsin-like specificities.
Pletnev VZ, Zamolodchikova TS, Pangborn WA, Duax WL
Proteins41(1)8-16(2000 Oct)
Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa. Purification and properties.
Zamolodchikova TS, Vorotyntseva TI, Antonov VK
European journal of biochemistry227(3)866-72(1995 Feb)
Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa. Primary structure of the enzyme.
Zamolodchikova TS, Vorotyntseva TI, Nazimov IV, Grishina GA
European journal of biochemistry227(3)873-9(1995 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
It is a cytotoxic genes in the endometrium and hightly expressed in the peri-implantation endometrium.
Title: Expression profiles of perforin, granzyme B and granulysin genes during the estrous cycle and gestation in the bovine endometrium.
Duodenase interacted with P1 variants of antichymotrypsin via a suicide mechanism with stoichiometry of the process SI = 1.2.
Title: Effect of reactive center loop structure of antichymotrypsin on inhibition of duodenase activity.
The following GZMB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GZMB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41824 | |
Clone ID Related Accession (Same CDS sequence) | NM_174296.2 | |
Accession Version | NM_174296.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | duodenase-1 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF198965.1. On Jun 3, 2003 this sequence version replaced NM_174296.1. ##Evidence-Data-START## Transcript exon combination :: FJ176745.1, CB440167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145415, SAMN03145422 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGTCCTGC TCCTGCTCCT GGTGGCCCTT CTGTCCCCTA CTGGGGAGGC AGGGAAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776721.1 |
CDS | 23..778 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174296.2 |
1 | ATGGTCCTGC TCCTGCTCCT GGTGGCCCTT CTGTCCCCTA CTGGGGAGGC AGGGAAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Expression profiles of perforin, granzyme B and granulysin genes during the estrous cycle and gestation in the bovine endometrium. |
Effect of reactive center loop structure of antichymotrypsin on inhibition of duodenase activity. |
Crystal structure of bovine duodenase, a serine protease, with dual trypsin and chymotrypsin-like specificities. |
Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa. Purification and properties. |
Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa. Primary structure of the enzyme. |