CCNA2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCNA2
Entrez Gene ID	281667
Full Name	cyclin A2
Synonyms	CCNA
General protein information	Preferred Names cyclin A2 Names cyclin-A2 cyclin-A
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001075123.1	NP_001068591.1	cyclin-A2
XM_010805858.2	XP_010804160.1	cyclin-A2 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ccna2	NP_446154.3
Gallus gallus (chicken)	CCNA2	NP_990575.1
Arabidopsis thaliana (thale cress)	CYCA2;3	NP_173010.1
Homo sapiens (human)	CCNA2	NP_001228.1
Pan troglodytes (chimpanzee)	CCNA2	XP_517420.1
Oryza sativa (rice)	Os12g0502300	NP_001066828.1
Xenopus tropicalis (tropical clawed frog)	ccna2	NP_001006768.1
Mus musculus (house mouse)	Ccna2	NP_033958.2
Danio rerio (zebrafish)	ccna2	NP_694481.1
Arabidopsis thaliana (thale cress)	CYCA2;4	NP_178153.1
	CCNA2	XP_001100860.1
Canis lupus familiaris (dog)	CCNA2	XP_540965.2
Bos taurus (cattle)	CCNA2	NP_001068591.1
Drosophila melanogaster (fruit fly)	CycA	NP_001246724.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012413	XP_320142.3

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Effects of polyadenylation inhibition on meiosis progression in relation to the polyadenylation status of cyclins A2 and B1 during in vitro maturation of bovine oocytes.
Traverso JM, Donnay I, Lequarre AS
Molecular reproduction and development71(1)107-14(2005 May)

B-Myb represses elastin gene expression in aortic smooth muscle cells.
Hofmann CS, Wang X, Sullivan CP, Toselli P, Stone PJ, McLean SE, Mecham RP, Schreiber BM, Sonenshein GE
The Journal of biological chemistry280(9)7694-701(2005 Mar)

B-Myb repressor function is regulated by cyclin A phosphorylation and sequences within the C-terminal domain.
Petrovas C, Jeay S, Lewis RE, Sonenshein GE
Oncogene22(13)2011-20(2003 Apr)

The crystal structure of cyclin A.
Brown NR, Noble ME, Endicott JA, Garman EF, Wakatsuki S, Mitchell E, Rasmussen B, Hunt T, Johnson LN
Structure (London, England : 1993)3(11)1235-47(1995 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

inconstant elongation of the poly(A) tail was observed for cyclin A2 transcripts after maturation
Title: Effects of polyadenylation inhibition on meiosis progression in relation to the polyadenylation status of cyclins A2 and B1 during in vitro maturation of bovine oocytes.

B-Myb represses SMC elastin gene expression and cyclin A plays a role in the developmental regulation of elastin gene expression in the aorta
Title: B-Myb represses elastin gene expression in aortic smooth muscle cells.

The following CCNA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCNA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43304	NM_001075123.1 Latest version!	Bos taurus cyclin A2 (CCNA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OBa45195	XM_010805858.2 Latest version!	Bos taurus cyclin A2 (CCNA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCNA2 ( NM_001075123.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001068591.1 Bos taurus cyclin A2 (CCNA2), mRNA.

Price & Availability↑

CloneID	OBa43304
Clone ID Related Accession (Same CDS sequence)	NM_001075123.1
Accession Version	NM_001075123.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Bos taurus(cattle)
Product	cyclin-A2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC118203.1. On or before Oct 4, 2006 this sequence version replaced XM_873308.1, XM_873403.1, XM_604021.2. ##Evidence-Data-START## Transcript exon combination :: BC118203.1, X68321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END##

ATGTTGGGCA GCTCCGCGCA CGGGCCTGCG GCCCGCGAGG CGGGTTCGGC GGTAACATTG 
CAGCAGACGG CGTTCCAGGA GGACCAGGAG AACGTCAATC CCGAGAAGGC GGCGCCCGCC 
CAGCAGCCCC GGACCCGGGC TGGACTGGCG GTACTGAGGG CCGGAAACTC GCGGGGTCCA 
GCTCCCCAGA GGCCTAAGAC GCGACGGGTT GCACCTCTTA AGGATCTTCC TATAAATGAT 
GAGTATGTCC CTGTTCCTCC CTGGAAAGCA AACAATAAAC AGCCTGCATT TACCATACAT 
GTGGATGAAG CAGAAGAAGA AATTCAAAAG AGGCCAACTG AATCTAAAAA ATCAGAAAGT 
GAAGATGTCT TGGCCTTTAA TTCAGCTGTT ACTTTACCAG GACCAAGAAA GCCACTGGCA 
CCTCTTGATT ACCCAATGGA TGGTAGTTTT GAGTCTCCAC ATACTATGGA AATGTCAGTT 
GTATTGGAAG ATGAAAAGCC AGTGAGTGTT AATGAAGTAC CAGACTACCA TGAGGACATT 
CACACGTACC TTAGGGAAAT GGAGGTTAAA TGTAAGCCTA AAGTGGGTTA CATGAAGAAA 
CAGCCAGACA TTACTAACAG TATGAGGGCT ATCCTCGTGG ACTGGTTAGT TGAAGTAGGA 
GAAGAATATA AACTGCAGAA CGAGACCCTG CATTTGGCTG TGAACTACAT TGATAGGTTT 
CTTTCATCCA TGTCTGTGTT GAGAGGAAAA CTTCAACTTG TGGGCACTGC TGCTATGCTT 
TTAGCCTCAA AGTTTGAAGA GATATACCCG CCAGAAGTAG CAGAGTTTGT ATACATTACA 
GATGACACTT ATACCAAGAA ACAAGTTCTA AGGATGGAGC ACCTAGTCTT GAAAGTCCTG 
GCTTTTGACT TAGCTGCACC AACAATAAAT CAGTTTCTTA CCCAGTACTT TTTGCATCAG 
CAGCCTGCAA ACTGCAAAGT TGAAAGTTTA GCAATGTTTT TGGGAGAGTT AAGTTTGATA 
GATGCTGACC CATATCTAAA GTATTTGCCG TCAGTTATCG CTGCAGCAGC CTTTCATTTA 
GCACTCTACA CAGTCACAGG ACAAAGCTGG CCTGAATCAT TAGTACAGAA GACTGGATAT 
ACTCTGGAAA CTCTAAAGCC TTGTCTCCTG GACCTTCACC AGACCTACCT CAGAGCACCA 
CAGCACGCAC AACAGTCAAT AAGAGAGAAG TACAAAAATT CAAAGTATCA TGGTGTTTCT 
CTCCTCAACC CACCAGAGAC ACTAAATGTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001068591.1
CDS	247..1539
Translation	MLGSSAHGPAAREAGSAVTLQQTAFQEDQENVNPEKAAPAQQPRTRAGLAVLRAGNSRGPAPQRPKTRRVAPLKDLPINDEYVPVPPWKANNKQPAFTIHVDEAEEEIQKRPTESKKSESEDVLAFNSAVTLPGPRKPLAPLDYPMDGSFESPHTMEMSVVLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIREKYKNSKYHGVSLLNPPETLNV

Target ORF information:

RefSeq Version	NM_001075123.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cyclin A2 (CCNA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001075123.1

ORF Insert Sequence:

ATGTTGGGCA GCTCCGCGCA CGGGCCTGCG GCCCGCGAGG CGGGTTCGGC GGTAACATTG 
CAGCAGACGG CGTTCCAGGA GGACCAGGAG AACGTCAATC CCGAGAAGGC GGCGCCCGCC 
CAGCAGCCCC GGACCCGGGC TGGACTGGCG GTACTGAGGG CCGGAAACTC GCGGGGTCCA 
GCTCCCCAGA GGCCTAAGAC GCGACGGGTT GCACCTCTTA AGGATCTTCC TATAAATGAT 
GAGTATGTCC CTGTTCCTCC CTGGAAAGCA AACAATAAAC AGCCTGCATT TACCATACAT 
GTGGATGAAG CAGAAGAAGA AATTCAAAAG AGGCCAACTG AATCTAAAAA ATCAGAAAGT 
GAAGATGTCT TGGCCTTTAA TTCAGCTGTT ACTTTACCAG GACCAAGAAA GCCACTGGCA 
CCTCTTGATT ACCCAATGGA TGGTAGTTTT GAGTCTCCAC ATACTATGGA AATGTCAGTT 
GTATTGGAAG ATGAAAAGCC AGTGAGTGTT AATGAAGTAC CAGACTACCA TGAGGACATT 
CACACGTACC TTAGGGAAAT GGAGGTTAAA TGTAAGCCTA AAGTGGGTTA CATGAAGAAA 
CAGCCAGACA TTACTAACAG TATGAGGGCT ATCCTCGTGG ACTGGTTAGT TGAAGTAGGA 
GAAGAATATA AACTGCAGAA CGAGACCCTG CATTTGGCTG TGAACTACAT TGATAGGTTT 
CTTTCATCCA TGTCTGTGTT GAGAGGAAAA CTTCAACTTG TGGGCACTGC TGCTATGCTT 
TTAGCCTCAA AGTTTGAAGA GATATACCCG CCAGAAGTAG CAGAGTTTGT ATACATTACA 
GATGACACTT ATACCAAGAA ACAAGTTCTA AGGATGGAGC ACCTAGTCTT GAAAGTCCTG 
GCTTTTGACT TAGCTGCACC AACAATAAAT CAGTTTCTTA CCCAGTACTT TTTGCATCAG 
CAGCCTGCAA ACTGCAAAGT TGAAAGTTTA GCAATGTTTT TGGGAGAGTT AAGTTTGATA 
GATGCTGACC CATATCTAAA GTATTTGCCG TCAGTTATCG CTGCAGCAGC CTTTCATTTA 
GCACTCTACA CAGTCACAGG ACAAAGCTGG CCTGAATCAT TAGTACAGAA GACTGGATAT 
ACTCTGGAAA CTCTAAAGCC TTGTCTCCTG GACCTTCACC AGACCTACCT CAGAGCACCA 
CAGCACGCAC AACAGTCAAT AAGAGAGAAG TACAAAAATT CAAAGTATCA TGGTGTTTCT 
CTCCTCAACC CACCAGAGAC ACTAAATGTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCNA2 ( XM_010805858.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010804160.1 Bos taurus cyclin A2 (CCNA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45195
Clone ID Related Accession (Same CDS sequence)	XM_010805858.2
Accession Version	XM_010805858.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1176bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	cyclin-A2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103949.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010805858.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGGGCA GCTCCGCGCA CGGGCCTGCG GCCCGCGAGG CGGGTTCGGC GGTAACATTG 
CAGCAGACGG CGTTCCAGGA GGACCAGGAG AACGTCAATC CCGAGAAGGC GGCGCCCGCC 
CAGCAGCCCC GGACCCGGGC TGGACTGGCG GTACTGAGGG CCGGAAACTC GCGGGGTCCA 
GCTCCCCAGA GGCCTAAGAC GCGACGGGTT GCACCTCTTA AGGATCTTCC TATAAATGAT 
GAGTATGTCC CTGTTCCTCC CTGGAAAGCA AACAATAAAC AGCCTGCATT TACCATACAT 
GTGGATGAAG CAGAAGAAAT TCAAAAGAGG CCAACTGAAT CTAAAAAATC AGAAAGTGAA 
GATGTCTTGG CCTTTAATTC AGCTGTTACT TTACCAGGAC CAAGAAAGCC ACTGGCACCT 
CTTGATTACC CAATGGATGG TAGTTTTGAG TCTCCACATA CTATGGAAAT GTCAGTTGTA 
TTGGAAGATG AAAAGCCAGT GAGTGTTAAT GAAGTACCAG ACTACCATGA GGACATTCAC 
ACGTACCTTA GGGAAATGGA GGTTAAATGT AAGCCTAAAG TGGGTTACAT GAAGAAACAG 
CCAGACATTA CTAACAGTAT GAGGGCTATC CTCGTGGACT GGTTAGTTGA AGTAGGAGAA 
GAATATAAAC TGCAGAACGA GACCCTGCAT TTGGCTGTGA ACTACATTGA TAGGTTTCTT 
TCATCCATGT CTGTGTTGAG AGGAAAACTT CAACTTGTGG GCACTGCTGC TATGCTTTTA 
GCCTCAAAGT TTGAAGAGAT ATACCCGCCA GAAGTAGCAG AGTTTGTATA CATTACAGAT 
GACACTTATA CCAAGAAACA AGTTCTAAGG ATGGAGCACC TAGTCTTGAA AGTCCTGGCT 
TTTGACTTAG CTGCACCAAC AATAAATCAG TTTCTTACCC AGTACTTTTT GCATCAGCAG 
CCTGCAAACT GCAAAGTTGA AAGTTTAGCA ATGCCTGAAT CATTAGTACA GAAGACTGGA 
TATACTCTGG AAACTCTAAA GCCTTGTCTC CTGGACCTTC ACCAGACCTA CCTCAGAGCA 
CCACAGCACG CACAACAGTC AATAAGAGAG AAGTACAAAA ATTCAAAGTA TCATGGTGTT 
TCTCTCCTCA ACCCACCAGA GACACTAAAT GTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010804160.1
CDS	1303..2478
Translation	MLGSSAHGPAAREAGSAVTLQQTAFQEDQENVNPEKAAPAQQPRTRAGLAVLRAGNSRGPAPQRPKTRRVAPLKDLPINDEYVPVPPWKANNKQPAFTIHVDEAEEIQKRPTESKKSESEDVLAFNSAVTLPGPRKPLAPLDYPMDGSFESPHTMEMSVVLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVESLAMPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIREKYKNSKYHGVSLLNPPETLNV

Target ORF information:

RefSeq Version	XM_010805858.2
Organism	Bos taurus(cattle)
Definition	Bos taurus cyclin A2 (CCNA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010805858.2

ORF Insert Sequence:

ATGTTGGGCA GCTCCGCGCA CGGGCCTGCG GCCCGCGAGG CGGGTTCGGC GGTAACATTG 
CAGCAGACGG CGTTCCAGGA GGACCAGGAG AACGTCAATC CCGAGAAGGC GGCGCCCGCC 
CAGCAGCCCC GGACCCGGGC TGGACTGGCG GTACTGAGGG CCGGAAACTC GCGGGGTCCA 
GCTCCCCAGA GGCCTAAGAC GCGACGGGTT GCACCTCTTA AGGATCTTCC TATAAATGAT 
GAGTATGTCC CTGTTCCTCC CTGGAAAGCA AACAATAAAC AGCCTGCATT TACCATACAT 
GTGGATGAAG CAGAAGAAAT TCAAAAGAGG CCAACTGAAT CTAAAAAATC AGAAAGTGAA 
GATGTCTTGG CCTTTAATTC AGCTGTTACT TTACCAGGAC CAAGAAAGCC ACTGGCACCT 
CTTGATTACC CAATGGATGG TAGTTTTGAG TCTCCACATA CTATGGAAAT GTCAGTTGTA 
TTGGAAGATG AAAAGCCAGT GAGTGTTAAT GAAGTACCAG ACTACCATGA GGACATTCAC 
ACGTACCTTA GGGAAATGGA GGTTAAATGT AAGCCTAAAG TGGGTTACAT GAAGAAACAG 
CCAGACATTA CTAACAGTAT GAGGGCTATC CTCGTGGACT GGTTAGTTGA AGTAGGAGAA 
GAATATAAAC TGCAGAACGA GACCCTGCAT TTGGCTGTGA ACTACATTGA TAGGTTTCTT 
TCATCCATGT CTGTGTTGAG AGGAAAACTT CAACTTGTGG GCACTGCTGC TATGCTTTTA 
GCCTCAAAGT TTGAAGAGAT ATACCCGCCA GAAGTAGCAG AGTTTGTATA CATTACAGAT 
GACACTTATA CCAAGAAACA AGTTCTAAGG ATGGAGCACC TAGTCTTGAA AGTCCTGGCT 
TTTGACTTAG CTGCACCAAC AATAAATCAG TTTCTTACCC AGTACTTTTT GCATCAGCAG 
CCTGCAAACT GCAAAGTTGA AAGTTTAGCA ATGCCTGAAT CATTAGTACA GAAGACTGGA 
TATACTCTGG AAACTCTAAA GCCTTGTCTC CTGGACCTTC ACCAGACCTA CCTCAGAGCA 
CCACAGCACG CACAACAGTC AATAAGAGAG AAGTACAAAA ATTCAAAGTA TCATGGTGTT 
TCTCTCCTCA ACCCACCAGA GACACTAAAT GTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Effects of polyadenylation inhibition on meiosis progression in relation to the polyadenylation status of cyclins A2 and B1 during in vitro maturation of bovine oocytes.
Molecular reproduction and development71(1)107-14(2005 May)
Traverso JM,Donnay I,Lequarre AS

B-Myb represses elastin gene expression in aortic smooth muscle cells.
The Journal of biological chemistry280(9)7694-701(2005 Mar)
Hofmann CS,Wang X,Sullivan CP,Toselli P,Stone PJ,McLean SE,Mecham RP,Schreiber BM,Sonenshein GE

B-Myb repressor function is regulated by cyclin A phosphorylation and sequences within the C-terminal domain.
Oncogene22(13)2011-20(2003 Apr)
Petrovas C,Jeay S,Lewis RE,Sonenshein GE

The crystal structure of cyclin A.
Structure (London, England : 1993)3(11)1235-47(1995 Nov)
Brown NR,Noble ME,Endicott JA,Garman EF,Wakatsuki S,Mitchell E,Rasmussen B,Hunt T,Johnson LN

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CCNA2 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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