Gene Symbol | XIAP |
Entrez Gene ID | 281647 |
Full Name | X-linked inhibitor of apoptosis |
Synonyms | BIRC4 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » XIAP cDNA ORF clone
Gene Symbol | XIAP |
Entrez Gene ID | 281647 |
Full Name | X-linked inhibitor of apoptosis |
Synonyms | BIRC4 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_010821346.2 | XP_010819648.1 | E3 ubiquitin-protein ligase XIAP isoform X1 |
XM_024987764.1 | XP_024843532.1 | E3 ubiquitin-protein ligase XIAP isoform X1 |
XM_024987765.1 | XP_024843533.1 | E3 ubiquitin-protein ligase XIAP isoform X1 |
XM_010821346.3 | XP_010819648.1 | E3 ubiquitin-protein ligase XIAP isoform X1 |
NM_001205592.1 | NP_001192521.1 | E3 ubiquitin-protein ligase XIAP |
Homo sapiens (human) | XIAP | NP_001158.2 |
Bos taurus (cattle) | XIAP | NP_001192521.1 |
Rattus norvegicus (Norway rat) | Xiap | NP_071567.1 |
Gallus gallus (chicken) | XIAP | NP_989919.1 |
Anopheles gambiae (African malaria mosquito) | IAP3 | XP_308528.2 |
Pan troglodytes (chimpanzee) | XIAP | XP_529138.2 |
Canis lupus familiaris (dog) | XIAP | XP_005641830.1 |
Anopheles gambiae (African malaria mosquito) | IAP7 | XP_001237095.2 |
Anopheles gambiae (African malaria mosquito) | IAP4 | XP_308529.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012677 | XP_560812.1 |
Mus musculus (house mouse) | Xiap | NP_033818.2 |
Danio rerio (zebrafish) | xiap | NP_919377.2 |
Xenopus tropicalis (tropical clawed frog) | xiap | NP_001025583.1 |
XIAP reverses various functional activities of FRNK in endothelial cells.
Ahn S, Kim HJ, Chi SG, Park H
Biochemical and biophysical research communications419(2)419-24(2012 Mar)
XIAP is essential for shear stress-enhanced Tyr-576 phosphorylation of FAK.
Ahn S, Park H
Biochemical and biophysical research communications399(2)256-61(2010 Aug)
X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration.
Kim J, Ahn S, Ko YG, Boo YC, Chi SG, Ni CW, Go YM, Jo H, Park H
American journal of physiology. Heart and circulatory physiology299(2)H300-9(2010 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.
Kim J, Park J, Choi S, Chi SG, Mowbray AL, Jo H, Park H
Circulation research102(8)896-904(2008 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
XIAP plays a key role in vascular functions of FRNK or FRNK domain-mediated vascular functions of FAK.
Title: XIAP reverses various functional activities of FRNK in endothelial cells.
these results demonstrate that XIAP plays a key role in shear stress-stimulated ERK activation by maintaining the Src-accessible location of FAK.
Title: XIAP is essential for shear stress-enhanced Tyr-576 phosphorylation of FAK.
Results indicate that XIAP stabilizes the alpha(5)-integrin-associated focal adhesion complex, thereby further regulating endothelial cell adhesion and migration.
Title: X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration.
XIAP plays a novel role in endothelial cells, interacting with caveolin-1 and acting as a regulator of vascular antiatherogenic function.
Title: X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.
The following XIAP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XIAP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa38556 | |
Clone ID Related Accession (Same CDS sequence) | XM_010821346.2 , XM_024987764.1 , XM_024987765.1 , XM_010821346.3 , NM_001205592.1 | |
Accession Version | NM_001205592.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-29 | |
Organism | Bos taurus(cattle) | |
Product | E3 ubiquitin-protein ligase XIAP | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from NKLS02000030.1. On Apr 20, 2011 this sequence version replaced XM_583068.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5571258.2233.1, SRR5571259.35702.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001192521.1 |
CDS | 27..1520 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001205592.1 |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa38556 | |
Clone ID Related Accession (Same CDS sequence) | XM_010821346.2 , XM_024987764.1 , XM_024987765.1 , XM_010821346.3 , NM_001205592.1 | |
Accession Version | XM_010821346.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | E3 ubiquitin-protein ligase XIAP isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104654.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010821346.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_010819648.1 |
CDS | 145..1638 |
Translation |
Target ORF information:
Target ORF information:
|
XM_010821346.2 |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa38556 | |
Clone ID Related Accession (Same CDS sequence) | XM_010821346.2 , XM_024987764.1 , XM_024987765.1 , XM_010821346.3 , NM_001205592.1 | |
Accession Version | XM_024987764.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | E3 ubiquitin-protein ligase XIAP isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037357.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024843532.1 |
CDS | 282..1775 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024987764.1 |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa38556 | |
Clone ID Related Accession (Same CDS sequence) | XM_010821346.2 , XM_024987764.1 , XM_024987765.1 , XM_010821346.3 , NM_001205592.1 | |
Accession Version | XM_024987765.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | E3 ubiquitin-protein ligase XIAP isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037357.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024843533.1 |
CDS | 277..1770 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024987765.1 |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa38556 | |
Clone ID Related Accession (Same CDS sequence) | XM_010821346.2 , XM_024987764.1 , XM_024987765.1 , XM_010821346.3 , NM_001205592.1 | |
Accession Version | XM_010821346.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | E3 ubiquitin-protein ligase XIAP isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037357.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_010821346.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_010819648.1 |
CDS | 155..1648 |
Translation |
Target ORF information:
Target ORF information:
|
XM_010821346.3 |
1 | ATGACTTTTA ACAGTTTTGA AGGATCTAAA ACTTGTGTAC CTGCAGACAT CGATAAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
XIAP reverses various functional activities of FRNK in endothelial cells. |
XIAP is essential for shear stress-enhanced Tyr-576 phosphorylation of FAK. |
X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration. |
A whole-genome assembly of the domestic cow, Bos taurus. |
X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival. |