Gene Symbol | TPM1 |
Entrez Gene ID | 281544 |
Full Name | tropomyosin 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » TPM1 cDNA ORF clone
Gene Symbol | TPM1 |
Entrez Gene ID | 281544 |
Full Name | tropomyosin 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_024997256.1 | XP_024853024.1 | tropomyosin alpha-1 chain isoform X13 |
NM_001013590.2 | NP_001013608.1 | tropomyosin alpha-1 chain |
XM_024997245.1 | XP_024853013.1 | tropomyosin alpha-1 chain isoform X2 |
XM_024997246.1 | XP_024853014.1 | tropomyosin alpha-1 chain isoform X3 |
XM_024997248.1 | XP_024853016.1 | tropomyosin alpha-1 chain isoform X5 |
XM_024997250.1 | XP_024853018.1 | tropomyosin alpha-1 chain isoform X7 |
XM_024997251.1 | XP_024853019.1 | tropomyosin alpha-1 chain isoform X8 |
XM_024997253.1 | XP_024853021.1 | tropomyosin alpha-1 chain isoform X10 |
XM_024997258.1 | XP_024853026.1 | tropomyosin alpha-1 chain isoform X15 |
XM_024997249.1 | XP_024853017.1 | tropomyosin alpha-1 chain isoform X6 |
XM_024997252.1 | XP_024853020.1 | tropomyosin alpha-1 chain isoform X9 |
XM_024997254.1 | XP_024853022.1 | tropomyosin alpha-1 chain isoform X11 |
XM_024997260.1 | XP_024853028.1 | tropomyosin alpha-1 chain isoform X17 |
XM_024997244.1 | XP_024853012.1 | tropomyosin alpha-1 chain isoform X1 |
XM_024997247.1 | XP_024853015.1 | tropomyosin alpha-1 chain isoform X4 |
XM_024997255.1 | XP_024853023.1 | tropomyosin alpha-1 chain isoform X12 |
XM_024997257.1 | XP_024853025.1 | tropomyosin alpha-1 chain isoform X14 |
XM_024997259.1 | XP_024853027.1 | tropomyosin alpha-1 chain isoform X16 |
XM_024997261.1 | XP_024853029.1 | tropomyosin alpha-1 chain isoform X18 |
Bos taurus (cattle) | TPM1 | NP_001013608.1 |
Danio rerio (zebrafish) | tpm2 | NP_001002119.1 |
Caenorhabditis elegans (roundworm) | lev-11 | NP_001021695.1 |
Pan troglodytes (chimpanzee) | TPM1 | XP_001173556.2 |
TPM1 | XP_001104296.1 | |
Gallus gallus (chicken) | TPM1 | NP_990732.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001797 | XP_003435938.1 |
Drosophila melanogaster (fruit fly) | Tm1 | NP_732001.3 |
Homo sapiens (human) | TPM1 | NP_001018004.1 |
The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium.
Bai F, Caster HM, Dawson JF, Kawai M
Journal of molecular and cellular cardiology79123-32(2015 Feb)
DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.
Bai F, Groth HL, Kawai M
PloS one7(10)e47471(2012)
Electron microscopy and persistence length analysis of semi-rigid smooth muscle tropomyosin strands.
Sousa D, Cammarato A, Jang K, Graceffa P, Tobacman LS, Li XE, Lehman W
Biophysical journal99(3)862-8(2010 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Temperature-dependence of isometric tension and cross-bridge kinetics of cardiac muscle fibers reconstituted with a tropomyosin internal deletion mutant.
Lu X, Tobacman LS, Kawai M
Biophysical journal91(11)4230-40(2006 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The first step of hypertrophic cardiomyopathy pathogenesis with E99K is increased calcium sensitivity and decreased calcium cooperativity, which result in larger tension during partial activation to cause a diastolic problem.
Title: The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium.
over-inhibition of the actomyosin interaction by E40K and E54K Tm mutants leads to a decreased force-generating ability at systole, which is the main mechanism underlying the early pathogenesis of DCM.
Title: DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.
The tendency of smooth muscle tropomyosin to form semi-rigid polymers with continuous and undampened rigidity may compensate for the lack of troponin-based structural support in smooth muscles.
Title: Electron microscopy and persistence length analysis of semi-rigid smooth muscle tropomyosin strands.
Tm affects the conformation of actin so as to increase the area of hydrophobic interaction between actin and myosin molecules
Title: Temperature-dependence of isometric tension and cross-bridge kinetics of cardiac muscle fibers reconstituted with a tropomyosin internal deletion mutant.
Tropomyosin is primarily responsible for the change in the kinetic constants of the elementary steps of the cross bridge cycle.
Title: The effect of tropomyosin on force and elementary steps of the cross-bridge cycle in reconstituted bovine myocardium.
The following TPM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TPM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa42181 | |
Clone ID Related Accession (Same CDS sequence) | NM_001013590.2 | |
Accession Version | NM_001013590.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC102909.1. On Aug 28, 2005 this sequence version replaced NM_001013590.1. ##Evidence-Data-START## Transcript exon combination :: BC102909.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145418, SAMN03145450 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001013608.1 |
CDS | 81..935 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001013590.2 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219385 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997244.1 | |
Accession Version | XM_024997244.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853012.1 |
CDS | 111..857 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997244.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219386 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997245.1 | |
Accession Version | XM_024997245.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853013.1 |
CDS | 111..857 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997245.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219387 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997246.1 | |
Accession Version | XM_024997246.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853014.1 |
CDS | 111..857 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997246.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219388 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997247.1 | |
Accession Version | XM_024997247.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853015.1 |
CDS | 116..862 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997247.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219389 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997248.1 | |
Accession Version | XM_024997248.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853016.1 |
CDS | 116..862 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997248.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219390 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997249.1 | |
Accession Version | XM_024997249.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X6 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853017.1 |
CDS | 182..928 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997249.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219391 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997250.1 | |
Accession Version | XM_024997250.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X7 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853018.1 |
CDS | 111..848 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997250.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219392 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997251.1 | |
Accession Version | XM_024997251.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X8 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853019.1 |
CDS | 116..853 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997251.1 |
1 | ATGGCGGGGA GCAGCTCGCT GGAGGCGGTG CGGAGGAAGA TTCGGAGCCT GCAGGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219393 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997252.1 | |
Accession Version | XM_024997252.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X9 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853020.1 |
CDS | 198..1052 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997252.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219394 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997253.1 | |
Accession Version | XM_024997253.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X10 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853021.1 |
CDS | 210..1064 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997253.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219395 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997254.1 | |
Accession Version | XM_024997254.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X11 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853022.1 |
CDS | 199..1053 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997254.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219396 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997255.1 | |
Accession Version | XM_024997255.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X12 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853023.1 |
CDS | 199..1053 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997255.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219397 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997256.1 | |
Accession Version | XM_024997256.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X13 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853024.1 |
CDS | 199..1053 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997256.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219398 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997257.1 | |
Accession Version | XM_024997257.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X14 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853025.1 |
CDS | 198..1052 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997257.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219399 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997258.1 | |
Accession Version | XM_024997258.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X15 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853026.1 |
CDS | 198..1052 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997258.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219400 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997259.1 | |
Accession Version | XM_024997259.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X16 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853027.1 |
CDS | 198..1052 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997259.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219401 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997260.1 | |
Accession Version | XM_024997260.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X17 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853028.1 |
CDS | 199..1053 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997260.1 |
1 | ATGGACGCCA TCAAGAAGAA GATGCAGATG CTCAAGCTCG ACAAGGAGAA CGCCTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa219402 | |
Clone ID Related Accession (Same CDS sequence) | XM_024997261.1 | |
Accession Version | XM_024997261.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | tropomyosin alpha-1 chain isoform X18 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAAGTCA TTGAGAGCCG AGCCCAAAAG GATGAGGAGA AGATGGAGAT TCAGGAGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024853029.1 |
CDS | 893..1369 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024997261.1 |
1 | ATGAAAGTCA TTGAGAGCCG AGCCCAAAAG GATGAGGAGA AGATGGAGAT TCAGGAGATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium. |
DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges. |
Electron microscopy and persistence length analysis of semi-rigid smooth muscle tropomyosin strands. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Temperature-dependence of isometric tension and cross-bridge kinetics of cardiac muscle fibers reconstituted with a tropomyosin internal deletion mutant. |