TP53 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	TP53
Entrez Gene ID	281542
Full Name	tumor protein p53
General protein information	Preferred Names tumor protein p53 Names cellular tumor antigen p53 p53 tumor suppressor phosphoprotein tumor protein 53 tumor protein p53 (Li-Fraumeni syndrome) tumor suppressor p53
Gene Type	protein-coding
Organism	Bos taurus(cattle)
Genome	Chromosome: 19 Map Location: 19q15

mRNA and Protein(s)

mRNA	Protein	Name
XM_010815982.2	XP_010814284.1	cellular tumor antigen p53 isoform X1
XM_010815982.3	XP_010814284.1	cellular tumor antigen p53 isoform X1
NM_174201.2	NP_776626.1	cellular tumor antigen p53

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TP53	NP_001003210.1
Mus musculus (house mouse)	Trp53	NP_035770.2
Bos taurus (cattle)	TP53	NP_776626.1
Danio rerio (zebrafish)	tp53	NP_001258749.1
	TP53	NP_001040616.1
Xenopus tropicalis (tropical clawed frog)	tp53	NP_001001903.1
Homo sapiens (human)	TP53	NP_000537.3
Pan troglodytes (chimpanzee)	TP53	XP_001172077.2
Rattus norvegicus (Norway rat)	Tp53	NP_112251.2

Gene Ontology
Bibliography

Related articles in PubMed

P53-Mediated Repression of the Reprogramming in Cloned Bovine Embryos Through Direct Interaction with HDAC1 and Indirect Interaction with DNMT3A.
Ma PJ, Zhang H, Li R, Wang YS, Zhang Y, Hua S
Reproduction in domestic animals = Zuchthygiene50(3)400-9(2015 Jun)

Dispersal of an ancient retroposon in the TP53 promoter of Bovidae: phylogeny, novel mechanisms, and potential implications for cow milk persistency.
Dekel Y, Machluf Y, Ben-Dor S, Yifa O, Stoler A, Ben-Shlomo I, Bercovich D
BMC genomics1653(2015 Feb)

In vivo oocyte developmental competence is reduced in lean but not in obese superovulated dairy cows after intraovarian administration of IGF1.
Velazquez MA, Hadeler KG, Herrmann D, Kues WA, Ulbrich SE, Ulbrich S, Meyer HH, R?my B, Beckers JF, Sauerwein H, Niemann H
Reproduction (Cambridge, England)142(1)41-52(2011 Jul)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The effect of p53 expression on the development of cloned embryos, and its interaction with HDAC1 and DNMT3A are reported.
Title: P53-Mediated Repression of the Reprogramming in Cloned Bovine Embryos Through Direct Interaction with HDAC1 and Indirect Interaction with DNMT3A.

Bov-A2 insertion into the TP53 promoter in Antilopinae and Tragelaphini may not only provide a genetic network that regulates mammary involution, but can also answer the need for rapid mammary involution in Savanna antelopes
Title: Dispersal of an ancient retroposon in the TP53 promoter of Bovidae: phylogeny, novel mechanisms, and potential implications for cow milk persistency.

Results demonstrate that embryonic developmental potential is related to the time of first cleavage and that p66(shc), but not p53, is up-regulated in early arrested in vitro-produced bovine embryos.
Title: p66shc, but not p53, is involved in early arrest of in vitro-produced bovine embryos.

PI3K/Akt and p53 are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide
Title: Redox regulation of PI3K/Akt and p53 in bovine aortic endothelial cells exposed to hydrogen peroxide.

The following TP53 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TP53 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa43437	NM_174201.2 Latest version!	Bos taurus tumor protein p53 (TP53), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OBa45162	XM_010815982.3 Latest version!	Bos taurus tumor protein p53 (TP53), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
View Old Accession Versions >>
OBa45162	XM_010815982.2	Bos taurus tumor protein p53 (TP53), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TP53 ( NM_174201.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776626.1 Bos taurus tumor protein p53 (TP53), mRNA.

Price & Availability↑

CloneID	OBa43437
Clone ID Related Accession (Same CDS sequence)	NM_174201.2
Accession Version	NM_174201.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Bos taurus(cattle)
Product	cellular tumor antigen p53
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC102440.1. On Aug 28, 2005 this sequence version replaced NM_174201.1. ##Evidence-Data-START## Transcript exon combination :: BC102440.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END##

ATGGAAGAAT CACAGGCAGA ACTCAATGTG GAGCCCCCTC TGAGTCAGGA GACATTTTCC 
GACTTGTGGA ACCTACTTCC TGAAAATAAC CTTCTGTCCT CCGAGCTCTC CGCACCCGTG 
GATGACCTGC TCCCGTACAC AGATGTTGCC ACCTGGCTGG ATGAATGTCC GAATGAAGCG 
CCCCAAATGC CAGAGCCTTC TGCCCCAGCT GCCCCGCCAC CAGCCACCCC AGCACCAGCC 
ACCTCCTGGC CCCTGTCGTC CTTTGTCCCC TCCCAGAAGA CCTACCCTGG CAATTACGGT 
TTCCGTCTAG GGTTCCTGCA ATCCGGAACA GCCAAGTCCG TGACCTGCAC GTATTCCCCT 
TCCCTTAACA AGCTGTTCTG CCAGCTGGCC AAGACCTGCC CAGTGCAGCT GTGGGTCGAC 
TCGCCACCCC CGCCCGGCAC CCGCGTCCGC GCCATGGCCA TCTACAAGAA GTTGGAGCAC 
ATGACGGAGG TTGTGAGGCG TTGTCCCCAC CATGAGCGCT CCTCTGACTA TAGCGATGGT 
CTGGCCCCTC CTCAGCACCT TATCCGGGTG GAAGGGAATT TACGCGCGGA GTATTTGGAC 
GACCGGAACA CCTTTAGACA CAGTGTGGTG GTGCCCTATG AGTCCCCCGA GATCGACTCT 
GAGTGCACCA CCATCCACTA CAATTTCATG TGTAACAGCT CCTGCATGGG GGGCATGAAC 
CGGCGGCCCA TCCTCACCAT CATCACACTG GAAGACTCTT GTGGTAACCT GCTGGGACGG 
AACAGCTTTG AGGTGCGTGT TTGTGCCTGT CCTGGGAGAG ACCGCCGCAC TGAGGAAGAA 
AATCTTCGCA AGAAGGGGCA GTCTTGCCCC GAGCCACCCC CTAGGAGCAC TAAGCGAGCA 
CTGCCTACCA ACACCAGCTC CTCTCCACAG CCAAAGAAGA AACCACTGGA TGGAGAGTAC 
TTCACTCTTC AGATCCGTGG GTTTAAACGC TATGAGATGT TCCGAGAGCT GAATGATGCC 
TTGGAGCTGA AGGATGCTCT GGATGGAAGG GAACCAGGGG AAAGCAGGGC TCACTCTAGC 
CACCTGAAGT CTAAGAAGAG GCCTTCTCCC TCCTGCCATA AAAAACCAAT GCTCAAGAGA 
GAGGGACCTG ACTCAGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776626.1
CDS	142..1302
Translation	MEESQAELNVEPPLSQETFSDLWNLLPENNLLSSELSAPVDDLLPYTDVATWLDECPNEAPQMPEPSAPAAPPPATPAPATSWPLSSFVPSQKTYPGNYGFRLGFLQSGTAKSVTCTYSPSLNKLFCQLAKTCPVQLWVDSPPPPGTRVRAMAIYKKLEHMTEVVRRCPHHERSSDYSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYESPEIDSECTTIHYNFMCNSSCMGGMNRRPILTIITLEDSCGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGQSCPEPPPRSTKRALPTNTSSSPQPKKKPLDGEYFTLQIRGFKRYEMFRELNDALELKDALDGREPGESRAHSSHLKSKKRPSPSCHKKPMLKREGPDSD

Target ORF information:

RefSeq Version	NM_174201.2
Organism	Bos taurus(cattle)
Definition	Bos taurus tumor protein p53 (TP53), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174201.2

ORF Insert Sequence:

ATGGAAGAAT CACAGGCAGA ACTCAATGTG GAGCCCCCTC TGAGTCAGGA GACATTTTCC 
GACTTGTGGA ACCTACTTCC TGAAAATAAC CTTCTGTCCT CCGAGCTCTC CGCACCCGTG 
GATGACCTGC TCCCGTACAC AGATGTTGCC ACCTGGCTGG ATGAATGTCC GAATGAAGCG 
CCCCAAATGC CAGAGCCTTC TGCCCCAGCT GCCCCGCCAC CAGCCACCCC AGCACCAGCC 
ACCTCCTGGC CCCTGTCGTC CTTTGTCCCC TCCCAGAAGA CCTACCCTGG CAATTACGGT 
TTCCGTCTAG GGTTCCTGCA ATCCGGAACA GCCAAGTCCG TGACCTGCAC GTATTCCCCT 
TCCCTTAACA AGCTGTTCTG CCAGCTGGCC AAGACCTGCC CAGTGCAGCT GTGGGTCGAC 
TCGCCACCCC CGCCCGGCAC CCGCGTCCGC GCCATGGCCA TCTACAAGAA GTTGGAGCAC 
ATGACGGAGG TTGTGAGGCG TTGTCCCCAC CATGAGCGCT CCTCTGACTA TAGCGATGGT 
CTGGCCCCTC CTCAGCACCT TATCCGGGTG GAAGGGAATT TACGCGCGGA GTATTTGGAC 
GACCGGAACA CCTTTAGACA CAGTGTGGTG GTGCCCTATG AGTCCCCCGA GATCGACTCT 
GAGTGCACCA CCATCCACTA CAATTTCATG TGTAACAGCT CCTGCATGGG GGGCATGAAC 
CGGCGGCCCA TCCTCACCAT CATCACACTG GAAGACTCTT GTGGTAACCT GCTGGGACGG 
AACAGCTTTG AGGTGCGTGT TTGTGCCTGT CCTGGGAGAG ACCGCCGCAC TGAGGAAGAA 
AATCTTCGCA AGAAGGGGCA GTCTTGCCCC GAGCCACCCC CTAGGAGCAC TAAGCGAGCA 
CTGCCTACCA ACACCAGCTC CTCTCCACAG CCAAAGAAGA AACCACTGGA TGGAGAGTAC 
TTCACTCTTC AGATCCGTGG GTTTAAACGC TATGAGATGT TCCGAGAGCT GAATGATGCC 
TTGGAGCTGA AGGATGCTCT GGATGGAAGG GAACCAGGGG AAAGCAGGGC TCACTCTAGC 
CACCTGAAGT CTAAGAAGAG GCCTTCTCCC TCCTGCCATA AAAAACCAAT GCTCAAGAGA 
GAGGGACCTG ACTCAGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TP53 ( XM_010815982.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010814284.1 Bos taurus tumor protein p53 (TP53), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45162
Clone ID Related Accession (Same CDS sequence)	XM_010815982.2 , XM_010815982.3
Accession Version	XM_010815982.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	cellular tumor antigen p53 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104494.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010815982.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGAGC CTTCTGCCCC AGCTGCCCCG CCACCAGCCA CCCCAGCACC AGCCACCTCC 
TGGCCCCTGT CGTCCTTTGT CCCCTCCCAG AAGACCTACC CTGGCAATTA CGGTTTCCGT 
CTAGGGTTCC TGCAATCCGG AACAGCCAAG TCCGTGACCT GCACGTATTC CCCTTCCCTT 
AACAAGCTGT TCTGCCAGCT GGCCAAGACC TGCCCAGTGC AGCTGTGGGT CGACTCGCCA 
CCCCCGCCCG GCACCCGCGT CCGCGCCATG GCCATCTACA AGAAGTTGGA GCACATGACG 
GAGGTTGTGA GGCGTTGTCC CCACCATGAG CGCTCCTCTG ACTATAGCGA TGGTCTGGCC 
CCTCCTCAGC ACCTTATCCG GGTGGAAGGG AATTTACGCG CGGAGTATTT GGACGACCGG 
AACACCTTTA GACACAGTGT GGTGGTGCCC TATGAGTCCC CCGAGATCGA CTCTGAGTGC 
ACCACCATCC ACTACAATTT CATGTGTAAC AGCTCCTGCA TGGGGGGCAT GAACCGGCGG 
CCCATCCTCA CCATCATCAC ACTGGAAGAC TCTTGTGGTA ACCTGCTGGG ACGGAACAGC 
TTTGAGGTGC GTGTTTGTGC CTGTCCTGGG AGAGACCGCC GCACTGAGGA AGAAAATCTT 
CGCAAGAAGG GGCAGTCTTG CCCCGAGCCA CCCCCTAGGA GCACTAAGCG AGCACTGCCT 
ACCAACACCA GCTCCTCTCC ACAGCCAAAG AAGAAACCAC TGGATGGAGA GTACTTCACT 
CTTCAGATCC GTGGGTTTAA ACGCTATGAG ATGTTCCGAG AGCTGAATGA TGCCTTGGAG 
CTGAAGGATG CTCTGGATGG AAGGGAACCA GGGGAAAGCA GGGCTCACTC TAGCCACCTG 
AAGTCTAAGA AGAGGCCTTC TCCCTCCTGC CATAAAAAAC CAATGCTCAA GAGAGAGGGG 
CCTGACTCAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010814284.1
CDS	431..1405
Translation	MPEPSAPAAPPPATPAPATSWPLSSFVPSQKTYPGNYGFRLGFLQSGTAKSVTCTYSPSLNKLFCQLAKTCPVQLWVDSPPPPGTRVRAMAIYKKLEHMTEVVRRCPHHERSSDYSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYESPEIDSECTTIHYNFMCNSSCMGGMNRRPILTIITLEDSCGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGQSCPEPPPRSTKRALPTNTSSSPQPKKKPLDGEYFTLQIRGFKRYEMFRELNDALELKDALDGREPGESRAHSSHLKSKKRPSPSCHKKPMLKREGPDSD

Target ORF information:

RefSeq Version	XM_010815982.2
Organism	Bos taurus(cattle)
Definition	Bos taurus tumor protein p53 (TP53), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010815982.2

ORF Insert Sequence:

ATGCCAGAGC CTTCTGCCCC AGCTGCCCCG CCACCAGCCA CCCCAGCACC AGCCACCTCC 
TGGCCCCTGT CGTCCTTTGT CCCCTCCCAG AAGACCTACC CTGGCAATTA CGGTTTCCGT 
CTAGGGTTCC TGCAATCCGG AACAGCCAAG TCCGTGACCT GCACGTATTC CCCTTCCCTT 
AACAAGCTGT TCTGCCAGCT GGCCAAGACC TGCCCAGTGC AGCTGTGGGT CGACTCGCCA 
CCCCCGCCCG GCACCCGCGT CCGCGCCATG GCCATCTACA AGAAGTTGGA GCACATGACG 
GAGGTTGTGA GGCGTTGTCC CCACCATGAG CGCTCCTCTG ACTATAGCGA TGGTCTGGCC 
CCTCCTCAGC ACCTTATCCG GGTGGAAGGG AATTTACGCG CGGAGTATTT GGACGACCGG 
AACACCTTTA GACACAGTGT GGTGGTGCCC TATGAGTCCC CCGAGATCGA CTCTGAGTGC 
ACCACCATCC ACTACAATTT CATGTGTAAC AGCTCCTGCA TGGGGGGCAT GAACCGGCGG 
CCCATCCTCA CCATCATCAC ACTGGAAGAC TCTTGTGGTA ACCTGCTGGG ACGGAACAGC 
TTTGAGGTGC GTGTTTGTGC CTGTCCTGGG AGAGACCGCC GCACTGAGGA AGAAAATCTT 
CGCAAGAAGG GGCAGTCTTG CCCCGAGCCA CCCCCTAGGA GCACTAAGCG AGCACTGCCT 
ACCAACACCA GCTCCTCTCC ACAGCCAAAG AAGAAACCAC TGGATGGAGA GTACTTCACT 
CTTCAGATCC GTGGGTTTAA ACGCTATGAG ATGTTCCGAG AGCTGAATGA TGCCTTGGAG 
CTGAAGGATG CTCTGGATGG AAGGGAACCA GGGGAAAGCA GGGCTCACTC TAGCCACCTG 
AAGTCTAAGA AGAGGCCTTC TCCCTCCTGC CATAAAAAAC CAATGCTCAA GAGAGAGGGG 
CCTGACTCAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TP53 ( XM_010815982.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010814284.1 Bos taurus tumor protein p53 (TP53), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa45162
Clone ID Related Accession (Same CDS sequence)	XM_010815982.2 , XM_010815982.3
Accession Version	XM_010815982.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	cellular tumor antigen p53 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037346.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_010815982.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGAGC CTTCTGCCCC AGCTGCCCCG CCACCAGCCA CCCCAGCACC AGCCACCTCC 
TGGCCCCTGT CGTCCTTTGT CCCCTCCCAG AAGACCTACC CTGGCAATTA CGGTTTCCGT 
CTAGGGTTCC TGCAATCCGG AACAGCCAAG TCCGTGACCT GCACGTATTC CCCTTCCCTT 
AACAAGCTGT TCTGCCAGCT GGCCAAGACC TGCCCAGTGC AGCTGTGGGT CGACTCGCCA 
CCCCCGCCCG GCACCCGCGT CCGCGCCATG GCCATCTACA AGAAGTTGGA GCACATGACG 
GAGGTTGTGA GGCGTTGTCC CCACCATGAG CGCTCCTCTG ACTATAGCGA TGGTCTGGCC 
CCTCCTCAGC ACCTTATCCG GGTGGAAGGG AATTTACGCG CGGAGTATTT GGACGACCGG 
AACACCTTTA GACACAGTGT GGTGGTGCCC TATGAGTCCC CCGAGATCGA CTCTGAGTGC 
ACCACCATCC ACTACAATTT CATGTGTAAC AGCTCCTGCA TGGGGGGCAT GAACCGGCGG 
CCCATCCTCA CCATCATCAC ACTGGAAGAC TCTTGTGGTA ACCTGCTGGG ACGGAACAGC 
TTTGAGGTGC GTGTTTGTGC CTGTCCTGGG AGAGACCGCC GCACTGAGGA AGAAAATCTT 
CGCAAGAAGG GGCAGTCTTG CCCCGAGCCA CCCCCTAGGA GCACTAAGCG AGCACTGCCT 
ACCAACACCA GCTCCTCTCC ACAGCCAAAG AAGAAACCAC TGGATGGAGA GTACTTCACT 
CTTCAGATCC GTGGGTTTAA ACGCTATGAG ATGTTCCGAG AGCTGAATGA TGCCTTGGAG 
CTGAAGGATG CTCTGGATGG AAGGGAACCA GGGGAAAGCA GGGCTCACTC TAGCCACCTG 
AAGTCTAAGA AGAGGCCTTC TCCCTCCTGC CATAAAAAAC CAATGCTCAA GAGAGAGGGG 
CCTGACTCAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010814284.1
CDS	447..1421
Translation	MPEPSAPAAPPPATPAPATSWPLSSFVPSQKTYPGNYGFRLGFLQSGTAKSVTCTYSPSLNKLFCQLAKTCPVQLWVDSPPPPGTRVRAMAIYKKLEHMTEVVRRCPHHERSSDYSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYESPEIDSECTTIHYNFMCNSSCMGGMNRRPILTIITLEDSCGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGQSCPEPPPRSTKRALPTNTSSSPQPKKKPLDGEYFTLQIRGFKRYEMFRELNDALELKDALDGREPGESRAHSSHLKSKKRPSPSCHKKPMLKREGPDSD

Target ORF information:

RefSeq Version	XM_010815982.3
Organism	Bos taurus(cattle)
Definition	Bos taurus tumor protein p53 (TP53), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010815982.3

ORF Insert Sequence:

ATGCCAGAGC CTTCTGCCCC AGCTGCCCCG CCACCAGCCA CCCCAGCACC AGCCACCTCC 
TGGCCCCTGT CGTCCTTTGT CCCCTCCCAG AAGACCTACC CTGGCAATTA CGGTTTCCGT 
CTAGGGTTCC TGCAATCCGG AACAGCCAAG TCCGTGACCT GCACGTATTC CCCTTCCCTT 
AACAAGCTGT TCTGCCAGCT GGCCAAGACC TGCCCAGTGC AGCTGTGGGT CGACTCGCCA 
CCCCCGCCCG GCACCCGCGT CCGCGCCATG GCCATCTACA AGAAGTTGGA GCACATGACG 
GAGGTTGTGA GGCGTTGTCC CCACCATGAG CGCTCCTCTG ACTATAGCGA TGGTCTGGCC 
CCTCCTCAGC ACCTTATCCG GGTGGAAGGG AATTTACGCG CGGAGTATTT GGACGACCGG 
AACACCTTTA GACACAGTGT GGTGGTGCCC TATGAGTCCC CCGAGATCGA CTCTGAGTGC 
ACCACCATCC ACTACAATTT CATGTGTAAC AGCTCCTGCA TGGGGGGCAT GAACCGGCGG 
CCCATCCTCA CCATCATCAC ACTGGAAGAC TCTTGTGGTA ACCTGCTGGG ACGGAACAGC 
TTTGAGGTGC GTGTTTGTGC CTGTCCTGGG AGAGACCGCC GCACTGAGGA AGAAAATCTT 
CGCAAGAAGG GGCAGTCTTG CCCCGAGCCA CCCCCTAGGA GCACTAAGCG AGCACTGCCT 
ACCAACACCA GCTCCTCTCC ACAGCCAAAG AAGAAACCAC TGGATGGAGA GTACTTCACT 
CTTCAGATCC GTGGGTTTAA ACGCTATGAG ATGTTCCGAG AGCTGAATGA TGCCTTGGAG 
CTGAAGGATG CTCTGGATGG AAGGGAACCA GGGGAAAGCA GGGCTCACTC TAGCCACCTG 
AAGTCTAAGA AGAGGCCTTC TCCCTCCTGC CATAAAAAAC CAATGCTCAA GAGAGAGGGG 
CCTGACTCAG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

P53-Mediated Repression of the Reprogramming in Cloned Bovine Embryos Through Direct Interaction with HDAC1 and Indirect Interaction with DNMT3A.
Reproduction in domestic animals = Zuchthygiene50(3)400-9(2015 Jun)
Ma PJ,Zhang H,Li R,Wang YS,Zhang Y,Hua S

Dispersal of an ancient retroposon in the TP53 promoter of Bovidae: phylogeny, novel mechanisms, and potential implications for cow milk persistency.
BMC genomics1653(2015 Feb)
Dekel Y,Machluf Y,Ben-Dor S,Yifa O,Stoler A,Ben-Shlomo I,Bercovich D

In vivo oocyte developmental competence is reduced in lean but not in obese superovulated dairy cows after intraovarian administration of IGF1.
Reproduction (Cambridge, England)142(1)41-52(2011 Jul)
Velazquez MA,Hadeler KG,Herrmann D,Kues WA,Ulbrich SE,Ulbrich S,Meyer HH,R?my B,Beckers JF,Sauerwein H,Niemann H

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

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TP53 cDNA ORF clone, Bos taurus(cattle)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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