Gene Symbol | TLR4 |
Entrez Gene ID | 281536 |
Full Name | toll like receptor 4 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » TLR4 cDNA ORF clone
Gene Symbol | TLR4 |
Entrez Gene ID | 281536 |
Full Name | toll like receptor 4 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005210586.3 | XP_005210643.1 | toll-like receptor 4 isoform X1 |
XM_005210586.4 | XP_005210643.1 | toll-like receptor 4 isoform X2 |
NM_174198.6 | NP_776623.5 | toll-like receptor 4 precursor |
XM_024995446.1 | XP_024851214.1 | toll-like receptor 4 isoform X1 |
Mus musculus (house mouse) | Tlr4 | NP_067272.1 |
Danio rerio (zebrafish) | tlr4ba | NP_001124523.1 |
Pan troglodytes (chimpanzee) | TLR4 | NP_001138335.1 |
Gallus gallus (chicken) | TLR4 | NP_001025864.1 |
Homo sapiens (human) | TLR4 | NP_612564.1 |
TLR4 | NP_001032169.1 | |
Rattus norvegicus (Norway rat) | Tlr4 | NP_062051.1 |
Danio rerio (zebrafish) | tlr4al | XP_001919699.4 |
Danio rerio (zebrafish) | tlr4bb | NP_997978.1 |
Canis lupus familiaris (dog) | TLR4 | NP_001002950.2 |
Bos taurus (cattle) | TLR4 | NP_776623.5 |
Dominance effects estimation of TLR4 and CACNA2D1 genes for health and production traits using logistic regression.
Bagheri M, Zahmatkesh A
Journal of genetics96(6)1027-1031(2017 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Studied genetic diversity of the Toll-like receptor gene TLR4 in Czech Red and Czech Red Pied cattle. Found 8 SNPs, which were grouped into 18 haplotypes.
Title: Diversity of the TLR4 Immunity Receptor in Czech Native Cattle Breeds Revealed Using the Pacific Biosciences Sequencing Platform.
TLR4 polymorphisms are associated with lower reproductive Performance.
Title: Effect of Single Nucleotide Polymorphisms of Toll-Like Receptor 4 (TLR 4) on Reproductive Performance and Immune Function in Dairy Cows.
As a pilot study, the present results revealed that identified SNPs in IL8 and TLR4 genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 gene may be a potential candidate for such disease.
Title: Single Nucleotide Polymorphisms in IL8 and TLR4 Genes as Candidates for Digital Dermatitis Resistance/Susceptibility in Holstein Cattle.
STA3 facilitates TLR4-dependent IL-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cells.
Title: Signal transducer and activator of transcription-3 licenses Toll-like receptor 4-dependent interleukin (IL)-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cells.
Transcription levels of TLR2, TLR4, and CD14 in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.
Title: Changes in endometrial transcription of TLR2, TLR4, and CD14 during the first-week postpartum in dairy cows with retained placenta.
The following TLR4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa22402 | |
Clone ID Related Accession (Same CDS sequence) | XM_005210586.3 | |
Accession Version | XM_005210586.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | toll-like receptor 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104150.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005210586.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCCCTAC TCAACCTCTC TTTAGATTTG TCCTTGAACC CTTTAGACTT TATTGAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005210643.1 |
CDS | 723..2648 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005210586.3 |
1 | ATGCCCCTAC TCAACCTCTC TTTAGATTTG TCCTTGAACC CTTTAGACTT TATTGAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa01214 | |
Clone ID Related Accession (Same CDS sequence) | NM_174198.6 | |
Accession Version | NM_174198.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2526bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Bos taurus(cattle) | |
Product | toll-like receptor 4 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ839566.1. On Mar 8, 2007 this sequence version replaced NM_174198.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ839566.1, AY297040.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATGGCGC GTGCCCGCCT GGCTGCGGCT CTGATCCCAG CCACGGCCAT CCTCTCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776623.5 |
CDS | 471..2996 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174198.6 |
1 | ATGATGGCGC GTGCCCGCCT GGCTGCGGCT CTGATCCCAG CCACGGCCAT CCTCTCCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa236926 | |
Clone ID Related Accession (Same CDS sequence) | XM_024995446.1 | |
Accession Version | XM_024995446.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2280bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | toll-like receptor 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037335.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGATTTC CCAGATGTGA AATTAAGATT ATTGAAGACG ACACATTTCA GGGCCTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024851214.1 |
CDS | 347..2626 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024995446.1 |
1 | ATGGGATTTC CCAGATGTGA AATTAAGATT ATTGAAGACG ACACATTTCA GGGCCTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa236927 | |
Clone ID Related Accession (Same CDS sequence) | XM_005210586.4 | |
Accession Version | XM_005210586.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | toll-like receptor 4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037335.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005210586.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCCCTAC TCAACCTCTC TTTAGATTTG TCCTTGAACC CTTTAGACTT TATTGAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005210643.1 |
CDS | 721..2646 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005210586.4 |
1 | ATGCCCCTAC TCAACCTCTC TTTAGATTTG TCCTTGAACC CTTTAGACTT TATTGAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Dominance effects estimation of TLR4 and CACNA2D1 genes for health and production traits using logistic regression. |