Gene Symbol | RAC1 |
Entrez Gene ID | 281440 |
Full Name | Rac family small GTPase 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » RAC1 cDNA ORF clone
Gene Symbol | RAC1 |
Entrez Gene ID | 281440 |
Full Name | Rac family small GTPase 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_024984646.1 | XP_024840414.1 | ras-related C3 botulinum toxin substrate 1 isoform X1 |
NM_174163.2 | NP_776588.1 | ras-related C3 botulinum toxin substrate 1 precursor |
Canis lupus familiaris (dog) | RAC1 | NP_001003274.1 |
Bos taurus (cattle) | RAC1 | NP_776588.1 |
Danio rerio (zebrafish) | rac1a | NP_956065.1 |
Drosophila melanogaster (fruit fly) | Rac2 | NP_001261517.1 |
LOC717755 | XP_001109586.2 | |
Mus musculus (house mouse) | Rac1 | NP_033033.1 |
Drosophila melanogaster (fruit fly) | Rac1 | NP_476950.1 |
Arabidopsis thaliana (thale cress) | ROP1 | NP_190698.1 |
Arabidopsis thaliana (thale cress) | RAC6 | NP_195320.1 |
Xenopus tropicalis (tropical clawed frog) | rac1 | NP_001004840.1 |
Rattus norvegicus (Norway rat) | Rac1 | NP_599193.1 |
Gallus gallus (chicken) | RAC1 | NP_990348.1 |
Pan troglodytes (chimpanzee) | RAC1 | NP_001233310.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005445 | XP_315449.4 |
Homo sapiens (human) | RAC1 | NP_061485.1 |
Arabidopsis thaliana (thale cress) | ARAC1 | NP_179371.1 |
Oryza sativa (rice) | Os02g0120800 | NP_001045712.1 |
Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria.
Natsvlishvili N, Goguadze N, Zhuravliova E, Mikeladze D
BMC biochemistry1611(2015 Apr)
Rac1 modification by an electrophilic 15-deoxy ?(12,14)-prostaglandin J2 analog.
Wall SB, Oh JY, Mitchell L, Laube AH, Campbell SL, Renfrow MB, Landar A
Redox biology4346-54(2015)
Angiotensin-II and MARCKS: a hydrogen peroxide- and RAC1-dependent signaling pathway in vascular endothelium.
Kalwa H, Sartoretto JL, Sartoretto SM, Michel T
The Journal of biological chemistry287(34)29147-58(2012 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model.
Harraz MM, Marden JJ, Zhou W, Zhang Y, Williams A, Sharov VS, Nelson K, Luo M, Paulson H, Sch?neich C, Engelhardt JF
The Journal of clinical investigation118(2)659-70(2008 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Sig1R through Rac1 signaling induces mild oxidative stress that possibly is involved in the regulation of neuroplasticity
Title: Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria.
Rac1 modification by electrophiles such as 15-deoxy-delta(12,14)-prostaglandin J2 may alter redox signaling and vascular endothelial cells function.
Title: Rac1 modification by an electrophilic 15-deoxy ?(12,14)-prostaglandin J2 analog.
a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.
Title: Angiotensin-II and MARCKS: a hydrogen peroxide- and RAC1-dependent signaling pathway in vascular endothelium.
small G protein Rac1 is a key regulator of beta(3)Adrenergic receptor signaling in cultured aortic endothelial cells with potentially important implications for the pathways involved in adrenergic modulation of eNOS pathways in the vascular wall
Title: Epinephrine regulation of the endothelial nitric-oxide synthase: roles of RAC1 and beta3-adrenergic receptors in endothelial NO signaling.
the activation of Rac1 due to the cell-cell contact plays a critical role in the transcriptional up-regulation of p27Kip1 in vascular endothelial cells.
Title: Rac1-dependent transcriptional up-regulation of p27Kip1 by homophilic cell-cell contact in vascular endothelial cells.
The following RAC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41601 | |
Clone ID Related Accession (Same CDS sequence) | NM_174163.2 | |
Accession Version | NM_174163.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Bos taurus(cattle) | |
Product | ras-related C3 botulinum toxin substrate 1 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF175262.1. On Jun 3, 2003 this sequence version replaced NM_174163.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF175262.1, BC103061.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCAGGCCA TCAAGTGTGT GGTGGTGGGA GACGGAGCTG TGGGTAAGAC TTGCCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776588.1 |
CDS | 172..750 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174163.2 |
1 | ATGCAGGCCA TCAAGTGTGT GGTGGTGGGA GACGGAGCTG TGGGTAAGAC TTGCCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa230144 | |
Clone ID Related Accession (Same CDS sequence) | XM_024984646.1 | |
Accession Version | XM_024984646.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | ras-related C3 botulinum toxin substrate 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037352.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAGGCCA TCAAGTGTGT GGTGGTGGGA GACGGAGCTG TGGGTAAGAC TTGCCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024840414.1 |
CDS | 224..859 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024984646.1 |
1 | ATGCAGGCCA TCAAGTGTGT GGTGGTGGGA GACGGAGCTG TGGGTAAGAC TTGCCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria. |
Rac1 modification by an electrophilic 15-deoxy ?(12,14)-prostaglandin J2 analog. |
Angiotensin-II and MARCKS: a hydrogen peroxide- and RAC1-dependent signaling pathway in vascular endothelium. |
A whole-genome assembly of the domestic cow, Bos taurus. |
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model. |