PRP1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	PRP1
Entrez Gene ID	281429
Full Name	prolactin-related protein 1
Synonyms	GHE3
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174159.2	NP_776584.1	placental prolactin-related protein 1 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PRP14	NP_001091031.1
Bos taurus (cattle)	PRP9	NP_001033221.1
Bos taurus (cattle)	LOC100298767	XP_002697589.1
Bos taurus (cattle)	PRP4	NP_997613.2
Bos taurus (cattle)	PRP-VII	NP_001012286.1
Bos taurus (cattle)	PRP8	NP_001033289.1
Bos taurus (cattle)	PRP3	NP_776585.1
Bos taurus (cattle)	PRP1	NP_776584.1
Bos taurus (cattle)	PRP2	NP_001073846.2
Bos taurus (cattle)	PRP6	NP_991347.1

Gene Ontology
Bibliography

Related articles in PubMed

Curated eutherian third party data gene data sets.
Premzl M
Data in brief6208-13(2016 Mar)

Third party data gene data set of eutherian growth hormone genes.
Premzl M
Genomics data6166-9(2015 Dec)

Cleaved bovine prolactin-related protein-I stimulates vascular endothelial cell proliferation.
Ushizawa K, Takahashi T, Hosoe M, Kizaki K, Hashizume K
Molecular and cellular endocrinology323(2)277-81(2010 Jul)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Bovine prolactin-related protein-I is anchored to the extracellular matrix through interactions with type IV collagen.
Takahashi T, Yamada O, Soares MJ, Hashizume K
The Journal of endocrinology196(2)225-34(2008 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that cleaved PRP1 proliferates endothelial cells in vitro, and suggest that endothelial cell proliferation activity of cleaved PRP1 may be shared in specific bovine placentomal angiogenesis.
Title: Cleaved bovine prolactin-related protein-I stimulates vascular endothelial cell proliferation.

Interaction of bPRP-I with type IV collagen suggests that bPRP-I accumulates in extracellular matrix where it likely acts on cells traversing the bovine placentome.
Title: Bovine prolactin-related protein-I is anchored to the extracellular matrix through interactions with type IV collagen.

Identified novel prolactin-related proteins (PRPs) in caprine placenta, and indicated that PRP genes in caprine placenta have coordination functions for gestation, as they do in bovine.
Title: Gene expression profiles of novel caprine placental prolactin-related proteins similar to bovine placental prolactin-related proteins.

placental prolactin-related protein-I is identified as a major target of bovine binucleate trophoblast giant cell lectin binding
Title: In bovine binucleate trophoblast giant cells, pregnancy-associated glycoproteins and placental prolactin-related protein-I are conjugated to asparagine-linked N-acetylgalactosaminyl glycans.

The following PRP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41286	NM_174159.2 Latest version!	Bos taurus prolactin-related protein 1 (PRP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PRP1 ( NM_174159.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776584.1 Bos taurus prolactin-related protein 1 (PRP1), mRNA.

Price & Availability↑

CloneID	OBa41286
Clone ID Related Accession (Same CDS sequence)	NM_174159.2
Accession Version	NM_174159.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Bos taurus(cattle)
Product	placental prolactin-related protein 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J02944.1. On Jun 3, 2003 this sequence version replaced NM_174159.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J02944.1, BC149446.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCTCCAG CTCCCAGCTT CCGTGGACAC CAGTGGACTT ACAACCCTGT CCGAGGGTCC 
TGCCTGCTGC TGCTGCTGCT CATGTCTAAT CTGCTCCTGT GCCAAGGCAA ATCATGCCCG 
TCCTGCGGTC CTGACGTGTT TGTCTCCTTA CGGAAATCCT TTACAGACAG GTTTATGAAT 
GCCGCCAGCC TCTCCCATGA CTTCTATAAC CTTTCCACAA TAATGTTCAA TGAGTTTGAT 
GAAAAATATG CCCAGGGCAA ACTCTACTAT ATCAATGTCA CCAAGAGCTG CCACACCAAT 
TCCTTCCATG CTCCCGAAGA AAGAGATATA GTCCAGCAGA CGAACATTGA AGACCTTAGT 
AAGTGGACAC TCGTGTTGCT GTACTCCTGG AATAATCCTC TGCATCATCT AGTCACGGAG 
CTGCAGCATA TGAAAGAACT GTCAAACGCC TTCCTATCAA GCGCCACAAG GTTTGAGAAC 
ATGTCAGAGA AACTTCAAGC ATTCATAGAG CGTCAATTCA GCAAGATTAT TGTTCCAGTC 
TTGAATACGA TGATCCAGGC TCGCAGTAGC TGGACAGGAC TCCCATCCCT AATGTCCAGC 
GCTGAAGATA GGCGTCATTC GGAATTTTAT AACCTGTTCT ACTGCCTGCG CAGGGATTCA 
CGTAAAGTTG ACATGTACAT CAAGATCCTG ACGTGCCGAA CCCACAAAAC GTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776584.1
CDS	88..804
Translation	MAPAPSFRGHQWTYNPVRGSCLLLLLLMSNLLLCQGKSCPSCGPDVFVSLRKSFTDRFMNAASLSHDFYNLSTIMFNEFDEKYAQGKLYYINVTKSCHTNSFHAPEERDIVQQTNIEDLSKWTLVLLYSWNNPLHHLVTELQHMKELSNAFLSSATRFENMSEKLQAFIERQFSKIIVPVLNTMIQARSSWTGLPSLMSSAEDRRHSEFYNLFYCLRRDSRKVDMYIKILTCRTHKTC

Target ORF information:

RefSeq Version	NM_174159.2
Organism	Bos taurus(cattle)
Definition	Bos taurus prolactin-related protein 1 (PRP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174159.2

ORF Insert Sequence:

ATGGCTCCAG CTCCCAGCTT CCGTGGACAC CAGTGGACTT ACAACCCTGT CCGAGGGTCC 
TGCCTGCTGC TGCTGCTGCT CATGTCTAAT CTGCTCCTGT GCCAAGGCAA ATCATGCCCG 
TCCTGCGGTC CTGACGTGTT TGTCTCCTTA CGGAAATCCT TTACAGACAG GTTTATGAAT 
GCCGCCAGCC TCTCCCATGA CTTCTATAAC CTTTCCACAA TAATGTTCAA TGAGTTTGAT 
GAAAAATATG CCCAGGGCAA ACTCTACTAT ATCAATGTCA CCAAGAGCTG CCACACCAAT 
TCCTTCCATG CTCCCGAAGA AAGAGATATA GTCCAGCAGA CGAACATTGA AGACCTTAGT 
AAGTGGACAC TCGTGTTGCT GTACTCCTGG AATAATCCTC TGCATCATCT AGTCACGGAG 
CTGCAGCATA TGAAAGAACT GTCAAACGCC TTCCTATCAA GCGCCACAAG GTTTGAGAAC 
ATGTCAGAGA AACTTCAAGC ATTCATAGAG CGTCAATTCA GCAAGATTAT TGTTCCAGTC 
TTGAATACGA TGATCCAGGC TCGCAGTAGC TGGACAGGAC TCCCATCCCT AATGTCCAGC 
GCTGAAGATA GGCGTCATTC GGAATTTTAT AACCTGTTCT ACTGCCTGCG CAGGGATTCA 
CGTAAAGTTG ACATGTACAT CAAGATCCTG ACGTGCCGAA CCCACAAAAC GTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Curated eutherian third party data gene data sets.
Data in brief6208-13(2016 Mar)
Premzl M

Third party data gene data set of eutherian growth hormone genes.
Genomics data6166-9(2015 Dec)
Premzl M

Cleaved bovine prolactin-related protein-I stimulates vascular endothelial cell proliferation.
Molecular and cellular endocrinology323(2)277-81(2010 Jul)
Ushizawa K,Takahashi T,Hosoe M,Kizaki K,Hashizume K

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Bovine prolactin-related protein-I is anchored to the extracellular matrix through interactions with type IV collagen.
The Journal of endocrinology196(2)225-34(2008 Feb)
Takahashi T,Yamada O,Soares MJ,Hashizume K

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PRP1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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