Gene Symbol | PROC |
Entrez Gene ID | 281428 |
Full Name | protein C, inactivator of coagulation factors Va and VIIIa |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
ORF » Species Summary » Bos taurus » PROC cDNA ORF clone
Gene Symbol | PROC |
Entrez Gene ID | 281428 |
Full Name | protein C, inactivator of coagulation factors Va and VIIIa |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001166512.1 | NP_001159984.1 | vitamin K-dependent protein C precursor |
XM_005202188.3 | XP_005202245.1 | vitamin K-dependent protein C isoform X1 |
XM_015474377.1 | XP_015329863.1 | vitamin K-dependent protein C isoform X3 |
XM_024998472.1 | XP_024854240.1 | vitamin K-dependent protein C isoform X1 |
XM_010801786.2 | XP_010800088.1 | vitamin K-dependent protein C isoform X2 |
XM_015474372.1 | XP_015329858.1 | vitamin K-dependent protein C isoform X3 |
XM_015474372.2 | XP_015329858.1 | vitamin K-dependent protein C isoform X2 |
Homo sapiens (human) | PROC | NP_000303.1 |
Xenopus tropicalis (tropical clawed frog) | proc | NP_001015759.1 |
Mus musculus (house mouse) | Proc | NP_032960.3 |
Rattus norvegicus (Norway rat) | Proc | NP_036935.1 |
Gallus gallus (chicken) | PROC | NP_989772.1 |
PROC | XP_001087196.2 | |
Pan troglodytes (chimpanzee) | PROC | XP_515775.3 |
Canis lupus familiaris (dog) | LOC476104 | NP_001013871.1 |
Bos taurus (cattle) | PROC | NP_001159984.1 |
Danio rerio (zebrafish) | proca | NP_956650.1 |
Identification of activated protein C as a ghrelin endopeptidase in bovine plasma.
Satou M, Nishi Y, Hishinuma A, Hosoda H, Kangawa K, Sugimoto H
The Journal of endocrinology224(1)61-73(2015 Jan)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Prevention of thrombosis following deep arterial injury in rats by bovine activated protein C requiring co-administration of bovine protein S.
Malm K, Dahlb?ck B, Arnljots B
Thrombosis and haemostasis90(2)227-34(2003 Aug)
Amino acid sequence of the light chain of bovine protein C.
Fernlund P, Stenflo J
The Journal of biological chemistry257(20)12170-9(1982 Oct)
Amino acid sequence of the heavy chain of bovine protein C.
Stenflo J, Fernlund P
The Journal of biological chemistry257(20)12180-90(1982 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Activated protein c is a ghrelin endopeptidase.
Title: Identification of activated protein C as a ghrelin endopeptidase in bovine plasma.
Activated protein C(APC) combined with protein S(PS) had significant antithrombotic effect. APC combined with PS prolonged clotting time. Dependence on APC-cofactor activity of PS for expression of anticoagulant activity by APC.
Title: Prevention of thrombosis following deep arterial injury in rats by bovine activated protein C requiring co-administration of bovine protein S.
The following PROC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PROC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa44542 | |
Clone ID Related Accession (Same CDS sequence) | NM_001166512.1 , XM_010801786.2 | |
Accession Version | NM_001166512.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Bos taurus(cattle) | |
Product | vitamin K-dependent protein C precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from NKLS02000002.1. On Oct 27, 2009 this sequence version replaced XM_585990.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5571257.38843.1, SRR5571260.14092.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145415, SAMN03145416 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAGTGG CTGCAGCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001159984.1 |
CDS | 12..1454 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001166512.1 |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAGTGG CTGCAGCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa16231 | |
Clone ID Related Accession (Same CDS sequence) | XM_005202188.3 , XM_024998472.1 | |
Accession Version | XM_005202188.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | vitamin K-dependent protein C isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103830.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005202188.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAAACC AGATAAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005202245.1 |
CDS | 161..1744 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005202188.3 |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAAACC AGATAAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa16231 | |
Clone ID Related Accession (Same CDS sequence) | XM_005202188.3 , XM_024998472.1 | |
Accession Version | XM_024998472.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | vitamin K-dependent protein C isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAAACC AGATAAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024854240.1 |
CDS | 41..1624 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024998472.1 |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAAACC AGATAAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa44542 | |
Clone ID Related Accession (Same CDS sequence) | NM_001166512.1 , XM_010801786.2 | |
Accession Version | XM_010801786.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | vitamin K-dependent protein C isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103830.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010801786.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAGTGG CTGCAGCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_010800088.1 |
CDS | 160..1602 |
Translation |
Target ORF information:
Target ORF information:
|
XM_010801786.2 |
1 | ATGGCGGCAG GAGGGCAACC TTGCAGTTTC TCCGCGGCCC ACCCCAGTGG CTGCAGCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa87875 | |
Clone ID Related Accession (Same CDS sequence) | XM_015474377.1 , XM_015474372.1 , XM_015474372.2 | |
Accession Version | XM_015474377.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | vitamin K-dependent protein C isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103830.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGCAGC TTACAAGCCT CTTACTGTTC GTGACCATCT GGGGAATTTC CAGCACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015329863.1 |
CDS | 93..1472 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015474377.1 |
1 | ATGTGGCAGC TTACAAGCCT CTTACTGTTC GTGACCATCT GGGGAATTTC CAGCACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa87875 | |
Clone ID Related Accession (Same CDS sequence) | XM_015474377.1 , XM_015474372.1 , XM_015474372.2 | |
Accession Version | XM_015474372.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | vitamin K-dependent protein C isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103830.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGCAGC TTACAAGCCT CTTACTGTTC GTGACCATCT GGGGAATTTC CAGCACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015329858.1 |
CDS | 108..1487 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015474372.1 |
1 | ATGTGGCAGC TTACAAGCCT CTTACTGTTC GTGACCATCT GGGGAATTTC CAGCACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa87875 | |
Clone ID Related Accession (Same CDS sequence) | XM_015474377.1 , XM_015474372.1 , XM_015474372.2 | |
Accession Version | XM_015474372.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | vitamin K-dependent protein C isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_015474372.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGCAGC TTACAAGCCT CTTACTGTTC GTGACCATCT GGGGAATTTC CAGCACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015329858.1 |
CDS | 99..1478 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015474372.2 |
1 | ATGTGGCAGC TTACAAGCCT CTTACTGTTC GTGACCATCT GGGGAATTTC CAGCACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Identification of activated protein C as a ghrelin endopeptidase in bovine plasma. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Prevention of thrombosis following deep arterial injury in rats by bovine activated protein C requiring co-administration of bovine protein S. |
Amino acid sequence of the light chain of bovine protein C. |
Amino acid sequence of the heavy chain of bovine protein C. |