PKP1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	PKP1
Entrez Gene ID	281405
Full Name	plakophilin 1
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174145.2	NP_776570.1	plakophilin-1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pkp1	NP_062619.1
Canis lupus familiaris (dog)	PKP1	XP_856621.1
Homo sapiens (human)	PKP1	NP_001005337.1
	PKP1	XP_002802045.1
Canis lupus familiaris (dog)	LOC100855871	XP_003639190.1
Rattus norvegicus (Norway rat)	Pkp1	NP_001100651.1
Gallus gallus (chicken)	PKP1	XP_419240.3
Pan troglodytes (chimpanzee)	PKP1	XP_003308733.1
Bos taurus (cattle)	PKP1	NP_776570.1
Danio rerio (zebrafish)	pkp1b	XP_001338299.2
Xenopus tropicalis (tropical clawed frog)	pkp1	XP_002932184.2

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis.
Hofmann I, Mertens C, Brettel M, Nimmrich V, Schn?lzer M, Herrmann H
Journal of cell science113 ( Pt 13)2471-83(2000 Jul)

Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components.
Schmidt A, Langbein L, Rode M, Pr?tzel S, Zimbelmann R, Franke WW
Cell and tissue research290(3)481-99(1997 Dec)

Cell type-specific desmosomal plaque proteins of the plakoglobin family: plakophilin 1 (band 6 protein).
Heid HW, Schmidt A, Zimbelmann R, Sch?fer S, Winter-Simanowski S, Stumpp S, Keith M, Figge U, Schn?lzer M, Franke WW
Differentiation; research in biological diversity58(2)113-31(1994 Dec)

Desmosomes and cytoskeletal architecture in epithelial differentiation: cell type-specific plaque components and intermediate filament anchorage.
Schmidt A, Heid HW, Sch?fer S, Nuber UA, Zimbelmann R, Franke WW
European journal of cell biology65(2)229-45(1994 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PKP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PKP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43618	NM_174145.2 Latest version!	Bos taurus plakophilin 1 (PKP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PKP1 ( NM_174145.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776570.1 Bos taurus plakophilin 1 (PKP1), mRNA.

Price & Availability↑

CloneID	OBa43618
Clone ID Related Accession (Same CDS sequence)	NM_174145.2
Accession Version	NM_174145.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2184bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Bos taurus(cattle)
Product	plakophilin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z37975.1. On or before Mar 29, 2005 this sequence version replaced XM_605979.1, NM_174145.1. ##Evidence-Data-START## Transcript exon combination :: Z37975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGAACCACT CGCCGCTCAA GACCGCCTTG GCCTACGAAT GCTTCCAGGA CCAGGACAAC 
TCGACGCTGG CTCTGCCGTC CGACCAGAAG ATGAAGACCG GCACGTCGGG CCGGCAGCGC 
GTGCAGGAAC AGGTGATGAT GACCGTCAAG CGGCAGAAGT CCAAGTCTTC CCAGTCGTCC 
ACCCTGAGCC ACTCCAACCG AGGCTCCATG TACGACGGCC TGGCCGACAG CTACAACAAC 
TACGGGACCA GCAGCCGGAG CAGCTTCTAC TCCAAGTTCC AGGCGGGGAG CGGCTCGTGG 
GGCTACCCGA TATACAATGG GACCCTCAAG CGGGAGGCTG ACAACAGGCG CTTCAGCTCC 
TACAGCCAGA TGGAGAGCTG GGGCCGGCAG TACCCGCGGG GCGGCTGCAC CGCCGCAGGC 
GCCGGCAGCG ACATCTGCTT CATGCAGAAG ATCAAGGCCA GCCGCAGCGA GCCCGACCTC 
TACTGCGACC CCCGGGGCAC GCTGCGCAAG GGCACGCTGG GTGGCAAGGG CCACAAGACC 
ACCCAGAACC GCTACAGCTT CTACAGCACG TGCAGCGGCC AGAAGGCAGT CAAGAAGTAC 
CCGGGGCGCC CGCCCTCCTG CACCTCCAGG CAGGACCCCG TGTGCGTCCC GCCCACCTCC 
TGCACCAAGG ACCTGTCCTT CAGCCACTCC AGGGCCAGCT CCAAGATCTG CAGCGAGGAC 
ATTGAGTGCA GCGGGTTGAC CATCCCCAAG GCCGTGCAGT ACCTGAGCTC CCAGGACGAG 
AAGTGCCAGG CCATCGGGGC GTACTACATC CAGCACACCT GCTTCCAGGA CGAGTCTGCC 
AAGCAGCAGG TGTACCAGCT GGGTGGCATC TGCAAGCTGG TGGACCTGCT CCGCAGCCCC 
AACCAGAACG TGCAGCAGGC CGCAGCCGGG GCCCTGCGCA ACCTGGTGTT CCGCAGCACC 
ACCAACAAGC TGGAGACGCG GCGGCAGAAC GGCATCCGCG AGGCGGTCAG CCTCCTGAGG 
AGGACCGGGA GCACCGAGAT CCAGAAGCAG CTGACCGGGC TGCTCTGGAA CCTGTCCTCC 
ACCGACGAGC TGAAGGAGGA GCTGATCGCC GAGGCGCTGC CCGTGCTGGC TGACCGCGTC 
ATCATCCCCT TCTCGGGCTG GTGCGACGGC AACAGTAACC TGTCCCGTGA GCCCGTGGAC 
CCCGAGGTCT TCTTCAACGC CACCGGCTGC CTGAGGAATC TGAGCTCCGC AGACGTGGGC 
CGCCAGACCA TGCGCAACTA CACGGGGCTC ATCGACTCGC TCATGGCCTA CGTCCAGAAC 
TGCGTGGCAG CCAACCGCTG TGACGACAAG TCAGTGGAGA ACTGCATGTG CGTCCTCCAC 
AACCTCTCCT ACCGCCTGGA CGCCGAGGTG CCCACGCGCT ACCGCCAGCT GGAGTACAAC 
GCCCGCAACG CCTACACCGA CAAGTCCTCC ACCGGCTGCT TCAGCAACAA GAGCGACCGC 
ATGACGAACA ACAACTATGA TTGCCCGCTT CCCGAGGAAG AGCCCAACCC CAAGGGCAGC 
AGCTGGCTGT ACCACTCGGA CGCCGTCCGC ACCTACCTGA ACCTCATGGG CAAGAGCAAG 
AAGGACGCCA CCCTGGAGGC CTGCGCGGGC GCCCTGCAGA ACCTGACCGC CAGCAAGGGG 
CTGATGTCCA GTGGCATGAG CCAGCTGATC GGGCTGAAGG AGAAGGGCCT GCCCCACATC 
GCCCGCCTCC TGCAATCTGG CAACTCGGAC GTGGTGCGGT CCGGAGCCTC GCTCCTGAGC 
AACATGTCCC GCCACCCCGC GCTGCACAGG GTGATGGGGA CCCAAGTGTT CCCAGAGGTG 
ACCAGACTCC TCACCAGTCA CACTGGCAAC ACCAGCAACT CGGAGGACAT CCTGGCCTCG 
GCCTGCTACA CTGTGAGGAA CCTGATGGCC TCCCTGCCGG GCATGGCCAA GCAGCACTTC 
TCCAGCAGCA TGGTCAACAA CATCATCAAC CTGTGCCGCA GCAGCACCTC CCCCAAGGCT 
GCGGAGGCCG CCCGCCTCCT CCTGTCCGAC ATGTGGTCCA GCAGGGAGCT GCAGGGGCTG 
CTCAGGCAGC AAGGTTTCGA TAGGAGCATG CTGGGGACCT TAGCCGGGGC CAACAGCCTC 
AGGAACTTCA CCTCCCGATT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776570.1
CDS	146..2329
Translation	MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADSYNNYGTSSRSSFYSKFQAGSGSWGYPIYNGTLKREADNRRFSSYSQMESWGRQYPRGGCTAAGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGGKGHKTTQNRYSFYSTCSGQKAVKKYPGRPPSCTSRQDPVCVPPTSCTKDLSFSHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKCQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGSTEIQKQLTGLLWNLSSTDELKEELIAEALPVLADRVIIPFSGWCDGNSNLSREPVDPEVFFNATGCLRNLSSADVGRQTMRNYTGLIDSLMAYVQNCVAANRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTDKSSTGCFSNKSDRMTNNNYDCPLPEEEPNPKGSSWLYHSDAVRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPHIARLLQSGNSDVVRSGASLLSNMSRHPALHRVMGTQVFPEVTRLLTSHTGNTSNSEDILASACYTVRNLMASLPGMAKQHFSSSMVNNIINLCRSSTSPKAAEAARLLLSDMWSSRELQGLLRQQGFDRSMLGTLAGANSLRNFTSRF

Target ORF information:

RefSeq Version	NM_174145.2
Organism	Bos taurus(cattle)
Definition	Bos taurus plakophilin 1 (PKP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174145.2

ORF Insert Sequence:

ATGAACCACT CGCCGCTCAA GACCGCCTTG GCCTACGAAT GCTTCCAGGA CCAGGACAAC 
TCGACGCTGG CTCTGCCGTC CGACCAGAAG ATGAAGACCG GCACGTCGGG CCGGCAGCGC 
GTGCAGGAAC AGGTGATGAT GACCGTCAAG CGGCAGAAGT CCAAGTCTTC CCAGTCGTCC 
ACCCTGAGCC ACTCCAACCG AGGCTCCATG TACGACGGCC TGGCCGACAG CTACAACAAC 
TACGGGACCA GCAGCCGGAG CAGCTTCTAC TCCAAGTTCC AGGCGGGGAG CGGCTCGTGG 
GGCTACCCGA TATACAATGG GACCCTCAAG CGGGAGGCTG ACAACAGGCG CTTCAGCTCC 
TACAGCCAGA TGGAGAGCTG GGGCCGGCAG TACCCGCGGG GCGGCTGCAC CGCCGCAGGC 
GCCGGCAGCG ACATCTGCTT CATGCAGAAG ATCAAGGCCA GCCGCAGCGA GCCCGACCTC 
TACTGCGACC CCCGGGGCAC GCTGCGCAAG GGCACGCTGG GTGGCAAGGG CCACAAGACC 
ACCCAGAACC GCTACAGCTT CTACAGCACG TGCAGCGGCC AGAAGGCAGT CAAGAAGTAC 
CCGGGGCGCC CGCCCTCCTG CACCTCCAGG CAGGACCCCG TGTGCGTCCC GCCCACCTCC 
TGCACCAAGG ACCTGTCCTT CAGCCACTCC AGGGCCAGCT CCAAGATCTG CAGCGAGGAC 
ATTGAGTGCA GCGGGTTGAC CATCCCCAAG GCCGTGCAGT ACCTGAGCTC CCAGGACGAG 
AAGTGCCAGG CCATCGGGGC GTACTACATC CAGCACACCT GCTTCCAGGA CGAGTCTGCC 
AAGCAGCAGG TGTACCAGCT GGGTGGCATC TGCAAGCTGG TGGACCTGCT CCGCAGCCCC 
AACCAGAACG TGCAGCAGGC CGCAGCCGGG GCCCTGCGCA ACCTGGTGTT CCGCAGCACC 
ACCAACAAGC TGGAGACGCG GCGGCAGAAC GGCATCCGCG AGGCGGTCAG CCTCCTGAGG 
AGGACCGGGA GCACCGAGAT CCAGAAGCAG CTGACCGGGC TGCTCTGGAA CCTGTCCTCC 
ACCGACGAGC TGAAGGAGGA GCTGATCGCC GAGGCGCTGC CCGTGCTGGC TGACCGCGTC 
ATCATCCCCT TCTCGGGCTG GTGCGACGGC AACAGTAACC TGTCCCGTGA GCCCGTGGAC 
CCCGAGGTCT TCTTCAACGC CACCGGCTGC CTGAGGAATC TGAGCTCCGC AGACGTGGGC 
CGCCAGACCA TGCGCAACTA CACGGGGCTC ATCGACTCGC TCATGGCCTA CGTCCAGAAC 
TGCGTGGCAG CCAACCGCTG TGACGACAAG TCAGTGGAGA ACTGCATGTG CGTCCTCCAC 
AACCTCTCCT ACCGCCTGGA CGCCGAGGTG CCCACGCGCT ACCGCCAGCT GGAGTACAAC 
GCCCGCAACG CCTACACCGA CAAGTCCTCC ACCGGCTGCT TCAGCAACAA GAGCGACCGC 
ATGACGAACA ACAACTATGA TTGCCCGCTT CCCGAGGAAG AGCCCAACCC CAAGGGCAGC 
AGCTGGCTGT ACCACTCGGA CGCCGTCCGC ACCTACCTGA ACCTCATGGG CAAGAGCAAG 
AAGGACGCCA CCCTGGAGGC CTGCGCGGGC GCCCTGCAGA ACCTGACCGC CAGCAAGGGG 
CTGATGTCCA GTGGCATGAG CCAGCTGATC GGGCTGAAGG AGAAGGGCCT GCCCCACATC 
GCCCGCCTCC TGCAATCTGG CAACTCGGAC GTGGTGCGGT CCGGAGCCTC GCTCCTGAGC 
AACATGTCCC GCCACCCCGC GCTGCACAGG GTGATGGGGA CCCAAGTGTT CCCAGAGGTG 
ACCAGACTCC TCACCAGTCA CACTGGCAAC ACCAGCAACT CGGAGGACAT CCTGGCCTCG 
GCCTGCTACA CTGTGAGGAA CCTGATGGCC TCCCTGCCGG GCATGGCCAA GCAGCACTTC 
TCCAGCAGCA TGGTCAACAA CATCATCAAC CTGTGCCGCA GCAGCACCTC CCCCAAGGCT 
GCGGAGGCCG CCCGCCTCCT CCTGTCCGAC ATGTGGTCCA GCAGGGAGCT GCAGGGGCTG 
CTCAGGCAGC AAGGTTTCGA TAGGAGCATG CTGGGGACCT TAGCCGGGGC CAACAGCCTC 
AGGAACTTCA CCTCCCGATT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis.
Journal of cell science113 ( Pt 13)2471-83(2000 Jul)
Hofmann I,Mertens C,Brettel M,Nimmrich V,Schn?lzer M,Herrmann H

Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components.
Cell and tissue research290(3)481-99(1997 Dec)
Schmidt A,Langbein L,Rode M,Pr?tzel S,Zimbelmann R,Franke WW

Cell type-specific desmosomal plaque proteins of the plakoglobin family: plakophilin 1 (band 6 protein).
Differentiation; research in biological diversity58(2)113-31(1994 Dec)
Heid HW,Schmidt A,Zimbelmann R,Sch?fer S,Winter-Simanowski S,Stumpp S,Keith M,Figge U,Schn?lzer M,Franke WW

Desmosomes and cytoskeletal architecture in epithelial differentiation: cell type-specific plaque components and intermediate filament anchorage.
European journal of cell biology65(2)229-45(1994 Dec)
Schmidt A,Heid HW,Sch?fer S,Nuber UA,Zimbelmann R,Franke WW

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PKP1 cDNA ORF clone, Bos taurus(cattle)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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