Gene Symbol | MC1R |
Entrez Gene ID | 281298 |
Full Name | melanocortin 1 receptor |
Synonyms | MC1-R,MSHR |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » MC1R cDNA ORF clone
Gene Symbol | MC1R |
Entrez Gene ID | 281298 |
Full Name | melanocortin 1 receptor |
Synonyms | MC1-R,MSHR |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174108.2 | NP_776533.1 | melanocyte-stimulating hormone receptor |
Homo sapiens (human) | MC1R | NP_002377.4 |
Bos taurus (cattle) | MC1R | NP_776533.1 |
Pan troglodytes (chimpanzee) | MC1R | NP_001009152.1 |
Mus musculus (house mouse) | Mc1r | NP_032585.2 |
Canis lupus familiaris (dog) | MC1R | NP_001014304.1 |
Rattus norvegicus (Norway rat) | Mc1r | XP_006255857.1 |
Xenopus tropicalis (tropical clawed frog) | mc1r | XP_002937630.2 |
Gallus gallus (chicken) | MC1R | NP_001026633.1 |
Danio rerio (zebrafish) | mc1r | NP_851301.1 |
New variants in the melanocortin 1 receptor gene (MC1R) in Asian cattle.
Zhang Y, Li Q, Ye S, Faruque MO, Yu Y, Sun D, Zhang S, Wang Y
Animal genetics45(4)609-10(2014 Aug)
Identification of a major locus interacting with MC1R and modifying black coat color in an F? Nellore-Angus population.
Hanna LL, Sanders JO, Riley DG, Abbey CA, Gill CA
Genetics, selection, evolution : GSE464(2014 Jan)
Interaction of MC1R and PMEL alleles on solid coat colors in Highland cattle.
Schmutz SM, Dreger DL
Animal genetics44(1)9-13(2013 Feb)
Isolation and characteristics of the melanocortin 1 receptor gene (MC1R) in the Chinese yakow (Bos grunniens?Bos taurus).
Xi D, Wu M, Fan Y, Huo Y, Leng J, Gou X, Mao H, Deng W
Gene498(2)259-63(2012 May)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The e and E+ are the main MC1R haplotypes in taurine or intermediate breeds from China. The haplotypes defined by c.416C>T, c.583C>T and c.890T>C, found mostly in China and Bangladesh, are the typical haplotypes of Bos indicus.
Title: New variants in the melanocortin 1 receptor gene (MC1R) in Asian cattle.
Recombinants in a 5 Mb region surrounding the cluster of tyrosine kinase receptor genes implicated PDGFRA as the strongest positional candidate gene interacting with MC1R and modifying black coat color in an F Nellore-Angus population.
Title: Identification of a major locus interacting with MC1R and modifying black coat color in an F? Nellore-Angus population.
Six solid colors occur in Highland cattle: black, dun, silver dun and red, yellow, and white. These six coat colors are explained by a non-epistatic interaction of the genotypes at the MC1R and PMEL genes.
Title: Interaction of MC1R and PMEL alleles on solid coat colors in Highland cattle.
the relationship of polymorphism of the MC1R with coat colour
Title: Isolation and characteristics of the melanocortin 1 receptor gene (MC1R) in the Chinese yakow (Bos grunniens?Bos taurus).
Sequence analysis revealed variation in the TYRP1 (exon 5) and MC1R genes; restriction enzyme analysis of these two genes could distinguish between different colours of Hanwoo cattle.
Title: Molecular variation in pigmentation genes contributing to coat colour in native Korean Hanwoo cattle.
The following MC1R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MC1R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41726 | |
Clone ID Related Accession (Same CDS sequence) | NM_174108.2 | |
Accession Version | NM_174108.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | melanocyte-stimulating hormone receptor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF445642.1. On Jun 3, 2003 this sequence version replaced NM_174108.1. ##Evidence-Data-START## Transcript exon combination :: AF445642.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGCCTGCAC TTGGCTCCCA GAGGCGGCTG CTGGGTTCCC TTAACTGCAC GCCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776533.1 |
CDS | 284..1237 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174108.2 |
1 | ATGCCTGCAC TTGGCTCCCA GAGGCGGCTG CTGGGTTCCC TTAACTGCAC GCCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
New variants in the melanocortin 1 receptor gene (MC1R) in Asian cattle. |
Identification of a major locus interacting with MC1R and modifying black coat color in an F? Nellore-Angus population. |
Interaction of MC1R and PMEL alleles on solid coat colors in Highland cattle. |
Isolation and characteristics of the melanocortin 1 receptor gene (MC1R) in the Chinese yakow (Bos grunniens?Bos taurus). |
A whole-genome assembly of the domestic cow, Bos taurus. |