Gene Symbol | IL1B |
Entrez Gene ID | 281251 |
Full Name | interleukin 1 beta |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
ORF » Species Summary » Bos taurus » IL1B cDNA ORF clone
Gene Symbol | IL1B |
Entrez Gene ID | 281251 |
Full Name | interleukin 1 beta |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_174093.1 | NP_776518.1 | interleukin-1 beta precursor |
Homo sapiens (human) | IL1B | NP_000567.1 |
Canis lupus familiaris (dog) | IL1B | NP_001033060.1 |
Mus musculus (house mouse) | Il1b | NP_032387.1 |
Bos taurus (cattle) | IL1B | NP_776518.1 |
Rattus norvegicus (Norway rat) | Il1b | NP_113700.2 |
IL1B | NP_001036221.1 | |
Pan troglodytes (chimpanzee) | IL1B | XP_001147075.1 |
Xenopus tropicalis (tropical clawed frog) | il1b | XP_002932618.1 |
Evaluation of antigen specific interleukin-1? as a biomarker to detect cattle infected with Mycobacterium bovis.
Elnaggar MM, Abdellrazeq GS, Elsisy A, Mahmoud AH, Shyboub A, Sester M, Khaliel SA, Singh M, Torky HA, Davis WC
Tuberculosis (Edinburgh, Scotland)10553-59(2017 Jul)
Expression and localization of interleukin 1 beta and interleukin 1 receptor (type I) in the bovine endometrium and embryo.
Correia-?lvarez E, G?mez E, Mart?n D, Carrocera S, P?rez S, Otero J, Peynot N, Giraud-Delville C, Caama?o JN, Sandra O, Duranthon V, Mu?oz M
Journal of reproductive immunology1101-13(2015 Aug)
Inflammasome activation in bovine monocytes by extracellular ATP does not require the purinergic receptor P2X7.
Hussen J, D?vel A, Koy M, Schuberth HJ
Developmental and comparative immunology38(2)312-20(2012 Oct)
Role of TGF-?1 and TNF-? in IL-1? mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Roy S, Samanta K, Chakraborti T, Chowdhury A, Chakraborti S
Archives of biochemistry and biophysics513(1)61-9(2011 Sep)
Effect of VEGF (vascular endothelial growth factor) on expression of IL-8 (interleukin-8), IL-1beta and their receptors in bovine theca cells.
Murayama C, Kaji A, Miyauchi K, Matsui M, Miyamoto A, Shimizu T
Cell biology international34(5)531-6(2010 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 protein and IL1B and IL1R1 mRNA were detected.
Title: Expression and localization of interleukin 1 beta and interleukin 1 receptor (type I) in the bovine endometrium and embryo.
For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.
Title: Inflammasome activation in bovine monocytes by extracellular ATP does not require the purinergic receptor P2X7.
Role of TGF-beta1 and TNF-alpha in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Title: Role of TGF-?1 and TNF-? in IL-1? mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.
Title: Effect of VEGF (vascular endothelial growth factor) on expression of IL-8 (interleukin-8), IL-1beta and their receptors in bovine theca cells.
Data suggest an important regulatory mechanism of interleukin-1beta production, associated with microglial migration and proliferation, driven by ECM degradation and/or synthesis in an injured brain.
Title: Adhesion to fibronectin regulates interleukin-1 beta expression in microglial cells.
The following IL1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41448 | |
Clone ID Related Accession (Same CDS sequence) | NM_174093.1 | |
Accession Version | NM_174093.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | interleukin-1 beta precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M37211.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M37211.1, M35589.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05861785, SAMN05861799 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCAACCG TACCTGAACC CATCAACGAA ATGATGGCTT ACTACAGTGA CGAGAATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776518.1 |
CDS | 74..874 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174093.1 |
1 | ATGGCAACCG TACCTGAACC CATCAACGAA ATGATGGCTT ACTACAGTGA CGAGAATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Evaluation of antigen specific interleukin-1? as a biomarker to detect cattle infected with Mycobacterium bovis. |
Expression and localization of interleukin 1 beta and interleukin 1 receptor (type I) in the bovine endometrium and embryo. |
Inflammasome activation in bovine monocytes by extracellular ATP does not require the purinergic receptor P2X7. |
Role of TGF-?1 and TNF-? in IL-1? mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease. |
Effect of VEGF (vascular endothelial growth factor) on expression of IL-8 (interleukin-8), IL-1beta and their receptors in bovine theca cells. |