GGCX cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	GGCX
Entrez Gene ID	281190
Full Name	gamma-glutamyl carboxylase
General protein information	Preferred Names gamma-glutamyl carboxylase Names vitamin K-dependent gamma-carboxylase peptidyl-glutamate 4-carboxylase vitamin K gamma glutamyl carboxylase
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174066.2	NP_776491.1	vitamin K-dependent gamma-carboxylase

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GGCX	XP_515586.2
Canis lupus familiaris (dog)	GGCX	XP_532979.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006363	XP_316389.4
Homo sapiens (human)	GGCX	NP_000812.2
	GGCX	XP_001086474.1
Bos taurus (cattle)	GGCX	NP_776491.1
Mus musculus (house mouse)	Ggcx	NP_062776.1
Rattus norvegicus (Norway rat)	Ggcx	NP_113944.1
Xenopus tropicalis (tropical clawed frog)	ggcx	NP_001116905.1
Danio rerio (zebrafish)	LOC100537604	XP_003199342.1
Drosophila melanogaster (fruit fly)	GC	NP_001163323.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

In vitro and in vivo functional characterization of bovine vitamin K-dependent gamma-carboxylase expressed in Chinese hamster ovary cells.
Rehemtulla A, Roth DA, Wasley LC, Kuliopulos A, Walsh CT, Furie B, Furie BC, Kaufman RJ
Proceedings of the National Academy of Sciences of the United States of America90(10)4611-5(1993 May)

Cloning and expression of the cDNA for human gamma-glutamyl carboxylase.
Wu SM, Cheung WF, Frazier D, Stafford DW
Science (New York, N.Y.)254(5038)1634-6(1991 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GGCX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GGCX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa42426	NM_174066.2 Latest version!	Bos taurus gamma-glutamyl carboxylase (GGCX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GGCX ( NM_174066.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776491.1 Bos taurus gamma-glutamyl carboxylase (GGCX), mRNA.

Price & Availability↑

CloneID	OBa42426
Clone ID Related Accession (Same CDS sequence)	NM_174066.2
Accession Version	NM_174066.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Bos taurus(cattle)
Product	vitamin K-dependent gamma-carboxylase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L09726.1. On Jun 3, 2003 this sequence version replaced NM_174066.1. ##Evidence-Data-START## Transcript exon combination :: L09726.1, BC153832.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGTCT CCGCTCGGCC CGCGCGGGCC CCGCGGGGCT CAGACAAAGT AAAGAAAGAC 
AAGGCTGCAC AGACTTCAGG GCCCCGTCAG GGCAGCCGAA TGGGGAAACT GTTGGGTTTT 
GAGTGGACAG ATGTGTCCAG CTGGGAGAGG CTGGTGACCC TGCTGAATAG ACCCACGGAT 
CCTGCAGGCC TGGCAGTCTT CCGTTTTCTC TTCGGGCTGA TGATGGTGCT GGACATACCC 
CAGGAGCGTG GTCTCAGCTC CCTAGACCGA AGATACCTGG ATGGCCTGGA GGTGTGTCGC 
TTCCCCTTAC TGGACGCCCT GCAGCCACTG CCACTTGACT GGATGTATCT AATCTACACC 
ATCATGTTTC TGGGGGCACT GGGCATGATG CTGGGCCTGT GCTACCGGAT AAGCTGTGTG 
TTATTCCTGC TGCCATACTG GTATGTGTTT CTCCTGGACA AGACGTCGTG GAACAACCAC 
TCCTATCTGT ATGGCTTGTT GGCCTTTCAG CTGACATTTG TGGATGCACA CCACTACTGG 
TCTGTGGATG GCCTGCTGAG AGCCCGGAAG CGGAATGCCC ACGTGCCCCT TTGGAACTAT 
GCTGTGTTGC GTGGCCAGAT CTTCATCGTG TACTTCATTG CGGGCATAAA GAAGCTGGAC 
GCAGACTGGG TGGAAGGCTA CTCTATGGAA TACCTGTCAC GGCACTGGCT CTTCAGCCCT 
TTCAAACTTG TGTTGTCCGA GGAGATGACG AGTCTGCTGG TGGTGCACTG GTGCGGACTG 
CTGCTCGACC TCTCAGCCGG TTTCCTGCTC TTCTTTGATG CCTCAAGACC CATCGGCTTC 
GTCTTCGTGT CCTACTTCCA CTGCATGAAT TCCCAGCTTT TCAGCATTGG CATGTTCCCC 
TACGTCATGC TGGCCAGCAG CCCTCTCTTC TGCTCTCCTG AATGGCCTCG GAAGCTGGTA 
GCTCACTGCC CGAAAAAGCT GCAAGAGCTG CTGCCCCTCA GGACTGCCCC TCAGCCCAGC 
ACTTCCTGTA TGTATAAGAG GAGCCGGGCC AGAGGCAGTC AGAAGCCAGG GCTGCGCCAC 
AAGCTGAGCA CTGCCTTCAC CCTGCTCTAC CTCCTGGAGC AGCTCTTCTT GCCTTATTCC 
CACTTCCTCA CCCAGGGGTA CAACAACTGG ACCAACGGGC TATACGGCTA CTCTTGGGAC 
ATGATGGTGC ACTCCCGCTC CCACCAGCAC GTGAAGATCA CCTACCGTGA TGGCCGCACC 
GGTGAACTGG GCTACCTCAA CCCTGGGGTA TTCACACAGA GCCGGCGTTG GAAGGACCAT 
GCAGACATGC TGAAGCAATA TGCCACTTGC CTGAGCCGCC TGCTGCCCAA GTACAATGTC 
ACTGAGCCCC AGATCTACTT TGATATTTGG GTCTCCATCA ATGACCGCTT CCAGCAGAGG 
ATTTTTGACC CTCGTGTGGA CATCGTGCAG GCTGCCTGGT CGCCCTTCCA GCGTACACCT 
TGGCTGCAGC CACTGCTGAT GGACCTGTCT CCCTGGAGAA CTAAACTACA GGAGATCAAG 
AGCAGCCTGG ACAACCACAC CGAAGTGGTC TTCATTGCAG ATTTCCCTGG GCTGCACCTG 
GAGAACTTCG TGAGTGAAGA CCTGGGCAAC ACTAGCATCC AGCTGCTGCA GGGGGAGGTG 
ACCGTGGAGC TGGTGGCAGA ACAGAAGAAC CAGACTCTTC AGGAGGGAGA AAAAATGCAG 
TTGCCGGCTG GTGAGTACCA TAAGGTGTAC ACAGTGTCGT CCAGTCCTTC CTGCTACATG 
TACATCTACG TCAACACTAC AGAGGTTGCA CTCGAGCAAG ACCTGGCGTA TCTTCAAGAA 
TTGAAGGAGA AGGTGGAGAA TGGAAGTGAA ACAGGGCCTC TGCCTCCAGA GCTGCAACCT 
CTGCTCGAAG GGGAAGTCAA AGGCGGCCCT GAGCCAACAC CACTGGTCCA GACCTTCCTT 
AGACGCCAGC AAAGGCTCCA GGAGATTGAA CGCCGGCGAA ATGCCCCTTT CCACGAGCGA 
CTTGTCCGCT TCTTGCTGCG AAAGCTCTTT ATCTTTCGCC GCAGCTTTCT CATGACTTGT 
ATCTCACTTC GAAATCTGGC ATTTGGCCGC CCTTCCCTGG AGCAGCTGGC CCAAGAAGTG 
ACTTATGCCA ACTTGCGACC CTTTGAGCCA GCGGGAGAGC CGAGTCCTGT AAACACAGAT 
TCTTCTAATC CTAACCCTCC TGAGCCGGAT TCTCACCCTG TTCACTCAGA GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776491.1
CDS	62..2338
Translation	MAVSARPARAPRGSDKVKKDKAAQTSGPRQGSRMGKLLGFEWTDVSSWERLVTLLNRPTDPAGLAVFRFLFGLMMVLDIPQERGLSSLDRRYLDGLEVCRFPLLDALQPLPLDWMYLIYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFVDAHHYWSVDGLLRARKRNAHVPLWNYAVLRGQIFIVYFIAGIKKLDADWVEGYSMEYLSRHWLFSPFKLVLSEEMTSLLVVHWCGLLLDLSAGFLLFFDASRPIGFVFVSYFHCMNSQLFSIGMFPYVMLASSPLFCSPEWPRKLVAHCPKKLQELLPLRTAPQPSTSCMYKRSRARGSQKPGLRHKLSTAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYLNPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTPWLQPLLMDLSPWRTKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLQEGEKMQLPAGEYHKVYTVSSSPSCYMYIYVNTTEVALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRLQEIERRRNAPFHERLVRFLLRKLFIFRRSFLMTCISLRNLAFGRPSLEQLAQEVTYANLRPFEPAGEPSPVNTDSSNPNPPEPDSHPVHSEF

Target ORF information:

RefSeq Version	NM_174066.2
Organism	Bos taurus(cattle)
Definition	Bos taurus gamma-glutamyl carboxylase (GGCX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174066.2

ORF Insert Sequence:

ATGGCGGTCT CCGCTCGGCC CGCGCGGGCC CCGCGGGGCT CAGACAAAGT AAAGAAAGAC 
AAGGCTGCAC AGACTTCAGG GCCCCGTCAG GGCAGCCGAA TGGGGAAACT GTTGGGTTTT 
GAGTGGACAG ATGTGTCCAG CTGGGAGAGG CTGGTGACCC TGCTGAATAG ACCCACGGAT 
CCTGCAGGCC TGGCAGTCTT CCGTTTTCTC TTCGGGCTGA TGATGGTGCT GGACATACCC 
CAGGAGCGTG GTCTCAGCTC CCTAGACCGA AGATACCTGG ATGGCCTGGA GGTGTGTCGC 
TTCCCCTTAC TGGACGCCCT GCAGCCACTG CCACTTGACT GGATGTATCT AATCTACACC 
ATCATGTTTC TGGGGGCACT GGGCATGATG CTGGGCCTGT GCTACCGGAT AAGCTGTGTG 
TTATTCCTGC TGCCATACTG GTATGTGTTT CTCCTGGACA AGACGTCGTG GAACAACCAC 
TCCTATCTGT ATGGCTTGTT GGCCTTTCAG CTGACATTTG TGGATGCACA CCACTACTGG 
TCTGTGGATG GCCTGCTGAG AGCCCGGAAG CGGAATGCCC ACGTGCCCCT TTGGAACTAT 
GCTGTGTTGC GTGGCCAGAT CTTCATCGTG TACTTCATTG CGGGCATAAA GAAGCTGGAC 
GCAGACTGGG TGGAAGGCTA CTCTATGGAA TACCTGTCAC GGCACTGGCT CTTCAGCCCT 
TTCAAACTTG TGTTGTCCGA GGAGATGACG AGTCTGCTGG TGGTGCACTG GTGCGGACTG 
CTGCTCGACC TCTCAGCCGG TTTCCTGCTC TTCTTTGATG CCTCAAGACC CATCGGCTTC 
GTCTTCGTGT CCTACTTCCA CTGCATGAAT TCCCAGCTTT TCAGCATTGG CATGTTCCCC 
TACGTCATGC TGGCCAGCAG CCCTCTCTTC TGCTCTCCTG AATGGCCTCG GAAGCTGGTA 
GCTCACTGCC CGAAAAAGCT GCAAGAGCTG CTGCCCCTCA GGACTGCCCC TCAGCCCAGC 
ACTTCCTGTA TGTATAAGAG GAGCCGGGCC AGAGGCAGTC AGAAGCCAGG GCTGCGCCAC 
AAGCTGAGCA CTGCCTTCAC CCTGCTCTAC CTCCTGGAGC AGCTCTTCTT GCCTTATTCC 
CACTTCCTCA CCCAGGGGTA CAACAACTGG ACCAACGGGC TATACGGCTA CTCTTGGGAC 
ATGATGGTGC ACTCCCGCTC CCACCAGCAC GTGAAGATCA CCTACCGTGA TGGCCGCACC 
GGTGAACTGG GCTACCTCAA CCCTGGGGTA TTCACACAGA GCCGGCGTTG GAAGGACCAT 
GCAGACATGC TGAAGCAATA TGCCACTTGC CTGAGCCGCC TGCTGCCCAA GTACAATGTC 
ACTGAGCCCC AGATCTACTT TGATATTTGG GTCTCCATCA ATGACCGCTT CCAGCAGAGG 
ATTTTTGACC CTCGTGTGGA CATCGTGCAG GCTGCCTGGT CGCCCTTCCA GCGTACACCT 
TGGCTGCAGC CACTGCTGAT GGACCTGTCT CCCTGGAGAA CTAAACTACA GGAGATCAAG 
AGCAGCCTGG ACAACCACAC CGAAGTGGTC TTCATTGCAG ATTTCCCTGG GCTGCACCTG 
GAGAACTTCG TGAGTGAAGA CCTGGGCAAC ACTAGCATCC AGCTGCTGCA GGGGGAGGTG 
ACCGTGGAGC TGGTGGCAGA ACAGAAGAAC CAGACTCTTC AGGAGGGAGA AAAAATGCAG 
TTGCCGGCTG GTGAGTACCA TAAGGTGTAC ACAGTGTCGT CCAGTCCTTC CTGCTACATG 
TACATCTACG TCAACACTAC AGAGGTTGCA CTCGAGCAAG ACCTGGCGTA TCTTCAAGAA 
TTGAAGGAGA AGGTGGAGAA TGGAAGTGAA ACAGGGCCTC TGCCTCCAGA GCTGCAACCT 
CTGCTCGAAG GGGAAGTCAA AGGCGGCCCT GAGCCAACAC CACTGGTCCA GACCTTCCTT 
AGACGCCAGC AAAGGCTCCA GGAGATTGAA CGCCGGCGAA ATGCCCCTTT CCACGAGCGA 
CTTGTCCGCT TCTTGCTGCG AAAGCTCTTT ATCTTTCGCC GCAGCTTTCT CATGACTTGT 
ATCTCACTTC GAAATCTGGC ATTTGGCCGC CCTTCCCTGG AGCAGCTGGC CCAAGAAGTG 
ACTTATGCCA ACTTGCGACC CTTTGAGCCA GCGGGAGAGC CGAGTCCTGT AAACACAGAT 
TCTTCTAATC CTAACCCTCC TGAGCCGGAT TCTCACCCTG TTCACTCAGA GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

In vitro and in vivo functional characterization of bovine vitamin K-dependent gamma-carboxylase expressed in Chinese hamster ovary cells.
Proceedings of the National Academy of Sciences of the United States of America90(10)4611-5(1993 May)
Rehemtulla A,Roth DA,Wasley LC,Kuliopulos A,Walsh CT,Furie B,Furie BC,Kaufman RJ

Cloning and expression of the cDNA for human gamma-glutamyl carboxylase.
Science (New York, N.Y.)254(5038)1634-6(1991 Dec)
Wu SM,Cheung WF,Frazier D,Stafford DW

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GGCX cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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