CAV1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CAV1
Entrez Gene ID	281040
Full Name	caveolin 1
General protein information	Preferred Names caveolin 1 Names caveolin-1 caveolin 1, caveolae protein, 22kDa
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005205392.3	XP_005205449.1	caveolin-1 isoform X1
XM_005205392.4	XP_005205449.1	caveolin-1 isoform X1
XM_024990412.1	XP_024846180.1	caveolin-1 isoform X1
XM_005205391.3	XP_005205448.1	caveolin-1 isoform X1
XM_005205391.4	XP_005205448.1	caveolin-1 isoform X1
NM_174004.3	NP_776429.1	caveolin-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CAV1	NP_001129290.1
Xenopus tropicalis (tropical clawed frog)	cav1	NP_001015750.1
Canis lupus familiaris (dog)	CAV1	NP_001003296.1
Bos taurus (cattle)	CAV1	NP_776429.1
Mus musculus (house mouse)	Cav1	NP_031642.1
	CAV1	NP_001162085.1
Rattus norvegicus (Norway rat)	Cav1	NP_113744.2
Homo sapiens (human)	CAV1	NP_001744.2
Gallus gallus (chicken)	CAV1	NP_001099134.1
Danio rerio (zebrafish)	cav1	NP_997816.1

Gene Ontology
Bibliography

Related articles in PubMed

Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt signaling.
Trane AE, Hiob MA, Uy T, Pavlov D, Bernatchez P
European journal of pharmacology76646-55(2015 Nov)

Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance.
Trane AE, Pavlov D, Sharma A, Saqib U, Lau K, van Petegem F, Minshall RD, Roman LJ, Bernatchez PN
The Journal of biological chemistry289(19)13273-83(2014 May)

Resveratrol ameliorates high glucose and high-fat/sucrose diet-induced vascular hyperpermeability involving Cav-1/eNOS regulation.
Peng XL, Qu W, Wang LZ, Huang BQ, Ying CJ, Sun XF, Hao LP
PloS one9(11)e113716(2014)

Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism.
Karuppiah K, Druhan LJ, Chen CA, Smith T, Zweier JL, Sessa WC, Cardounel AJ
American journal of physiology. Heart and circulatory physiology301(3)H903-11(2011 Sep)

Caveolin-1 is required for vascular endothelial insulin uptake.
Wang H, Wang AX, Barrett EJ
American journal of physiology. Endocrinology and metabolism300(1)E134-44(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt signaling
Title: Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt signaling.

these data provide the first detailed analysis of Cav-1 binding to one of its most significant client proteins, eNOS.
Title: Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance.

Data show that resveratrol (Res) reversed caveolin-1 (Cav-1)/endothelial nitric oxide synthase (eNOS) expressions in high glucose cultured bovine aortic endothelial cells (BAECs).
Title: Resveratrol ameliorates high glucose and high-fat/sucrose diet-induced vascular hyperpermeability involving Cav-1/eNOS regulation.

Study identifies a critical role of caveolin-1 in the regulation of eNOS uncoupling via a biopterin-dependent mechanism.
Title: Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism.

Data indicate that caveolin-1 expression is required for insulin uptake by aortic endothelial cells.
Title: Caveolin-1 is required for vascular endothelial insulin uptake.

The following CAV1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CAV1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa41288	NM_174004.3 Latest version!	Bos taurus caveolin 1 (CAV1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa18538	XM_005205392.4 Latest version!	Bos taurus caveolin 1 (CAV1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa18538	XM_024990412.1 Latest version!	Bos taurus caveolin 1 (CAV1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa18538	XM_005205391.4 Latest version!	Bos taurus caveolin 1 (CAV1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
View Old Accession Versions >>
OBa18538	XM_005205392.3	Bos taurus caveolin 1 (CAV1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa18538	XM_005205391.3	Bos taurus caveolin 1 (CAV1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CAV1 ( NM_174004.3 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776429.1 Bos taurus caveolin 1 (CAV1), mRNA.

Price & Availability↑

CloneID	OBa41288
Clone ID Related Accession (Same CDS sequence)	NM_174004.3
Accession Version	NM_174004.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Bos taurus(cattle)
Product	caveolin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY823915.1. On Jan 12, 2005 this sequence version replaced NM_174004.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY823915.1, DV819176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145453 [ECO:0000348] ##Evidence-Data-END##

ATGTCGGGGG GCAAATACGT AGACTCAGAG GGACATCTCT ACACTGTTCC CATCCGGGAA 
CAGGGCAACA TCTACAAGCC CAACAACAAG GCTATGGCAG AGGAAATGAA CGAGAAGCAA 
GTGTACGACG CGCACACCAA GGAGATAGAT CTGGTCAACC GCGACCCCAA GCATCTCAAC 
GACGACGTGG TCAAGATTGA TTTTGAAGAT GTGATTGCAG AACCAGAAGG AACACACAGT 
TTCGATGGCA TCTGGAAGGC CAGCTTCACC ACCTTCACTG TGACAAAGTA CTGGTTTTAC 
CGTTTGCTGT CTGCCCTCTT TGGCATCCCA ATGGCACTCA TCTGGGGCAT TTACTTTGCC 
ATTCTCTCTT TCCTGCACAT CTGGGCAGTT GTACCATGCA TTAAGAGTTT CCTGATTGAG 
ATTCAGTGCA TCAGCCGTGT CTATTCCATC TACGTCCACA CCTTCTGTGA CCCGCTGTTT 
GAGGCTATTG GCAAAATATT CAGCAATATC CGCATCAACA CGCAGAAAGA AATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776429.1
CDS	63..599
Translation	MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINTQKEI

Target ORF information:

RefSeq Version	NM_174004.3
Organism	Bos taurus(cattle)
Definition	Bos taurus caveolin 1 (CAV1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174004.3

ORF Insert Sequence:

ATGTCGGGGG GCAAATACGT AGACTCAGAG GGACATCTCT ACACTGTTCC CATCCGGGAA 
CAGGGCAACA TCTACAAGCC CAACAACAAG GCTATGGCAG AGGAAATGAA CGAGAAGCAA 
GTGTACGACG CGCACACCAA GGAGATAGAT CTGGTCAACC GCGACCCCAA GCATCTCAAC 
GACGACGTGG TCAAGATTGA TTTTGAAGAT GTGATTGCAG AACCAGAAGG AACACACAGT 
TTCGATGGCA TCTGGAAGGC CAGCTTCACC ACCTTCACTG TGACAAAGTA CTGGTTTTAC 
CGTTTGCTGT CTGCCCTCTT TGGCATCCCA ATGGCACTCA TCTGGGGCAT TTACTTTGCC 
ATTCTCTCTT TCCTGCACAT CTGGGCAGTT GTACCATGCA TTAAGAGTTT CCTGATTGAG 
ATTCAGTGCA TCAGCCGTGT CTATTCCATC TACGTCCACA CCTTCTGTGA CCCGCTGTTT 
GAGGCTATTG GCAAAATATT CAGCAATATC CGCATCAACA CGCAGAAAGA AATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_005205392.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005205449.1 Bos taurus caveolin 1 (CAV1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa18538
Clone ID Related Accession (Same CDS sequence)	XM_005205392.3 , XM_005205392.4 , XM_024990412.1 , XM_005205391.3 , XM_005205391.4
Accession Version	XM_005205392.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	caveolin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103895.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005205392.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005205449.1
CDS	163..606
Translation	MAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINTQKEI

Target ORF information:

RefSeq Version	XM_005205392.3
Organism	Bos taurus(cattle)
Definition	Bos taurus caveolin 1 (CAV1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005205392.3

ORF Insert Sequence:

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_005205392.4 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005205449.1 Bos taurus caveolin 1 (CAV1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa18538
Clone ID Related Accession (Same CDS sequence)	XM_005205392.3 , XM_005205392.4 , XM_024990412.1 , XM_005205391.3 , XM_005205391.4
Accession Version	XM_005205392.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	caveolin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037331.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005205392.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005205449.1
CDS	190..633
Translation	MAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINTQKEI

Target ORF information:

RefSeq Version	XM_005205392.4
Organism	Bos taurus(cattle)
Definition	Bos taurus caveolin 1 (CAV1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005205392.4

ORF Insert Sequence:

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_024990412.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024846180.1 Bos taurus caveolin 1 (CAV1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OBa18538
Clone ID Related Accession (Same CDS sequence)	XM_005205392.3 , XM_005205392.4 , XM_024990412.1 , XM_005205391.3 , XM_005205391.4
Accession Version	XM_024990412.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	caveolin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037331.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024846180.1
CDS	156..599
Translation	MAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINTQKEI

Target ORF information:

RefSeq Version	XM_024990412.1
Organism	Bos taurus(cattle)
Definition	Bos taurus caveolin 1 (CAV1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024990412.1

ORF Insert Sequence:

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_005205391.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005205448.1 Bos taurus caveolin 1 (CAV1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa18538
Clone ID Related Accession (Same CDS sequence)	XM_005205392.3 , XM_005205392.4 , XM_024990412.1 , XM_005205391.3 , XM_005205391.4
Accession Version	XM_005205391.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	caveolin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103895.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005205391.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005205448.1
CDS	169..612
Translation	MAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINTQKEI

Target ORF information:

RefSeq Version	XM_005205391.3
Organism	Bos taurus(cattle)
Definition	Bos taurus caveolin 1 (CAV1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005205391.3

ORF Insert Sequence:

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_005205391.4 ) cDNA ORF clone, Bos taurus(cattle) -> XP_005205448.1 Bos taurus caveolin 1 (CAV1), transcript variant X1, mRNA.

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CloneID	OBa18538
Clone ID Related Accession (Same CDS sequence)	XM_005205392.3 , XM_005205392.4 , XM_024990412.1 , XM_005205391.3 , XM_005205391.4
Accession Version	XM_005205391.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	caveolin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037331.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005205391.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005205448.1
CDS	192..635
Translation	MAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINTQKEI

Target ORF information:

RefSeq Version	XM_005205391.4
Organism	Bos taurus(cattle)
Definition	Bos taurus caveolin 1 (CAV1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005205391.4

ORF Insert Sequence:

ATGGCAGAGG AAATGAACGA GAAGCAAGTG TACGACGCGC ACACCAAGGA GATAGATCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTC GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAGTACTG GTTTTACCGT TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATCT GGGGCATTTA CTTTGCCATT CTCTCTTTCC TGCACATCTG GGCAGTTGTA 
CCATGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GCTGTTTGAG GCTATTGGCA AAATATTCAG CAATATCCGC 
ATCAACACGC AGAAAGAAAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt signaling.
European journal of pharmacology76646-55(2015 Nov)
Trane AE,Hiob MA,Uy T,Pavlov D,Bernatchez P

Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance.
The Journal of biological chemistry289(19)13273-83(2014 May)
Trane AE,Pavlov D,Sharma A,Saqib U,Lau K,van Petegem F,Minshall RD,Roman LJ,Bernatchez PN

Resveratrol ameliorates high glucose and high-fat/sucrose diet-induced vascular hyperpermeability involving Cav-1/eNOS regulation.
PloS one9(11)e113716(2014)
Peng XL,Qu W,Wang LZ,Huang BQ,Ying CJ,Sun XF,Hao LP

Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism.
American journal of physiology. Heart and circulatory physiology301(3)H903-11(2011 Sep)
Karuppiah K,Druhan LJ,Chen CA,Smith T,Zweier JL,Sessa WC,Cardounel AJ

Caveolin-1 is required for vascular endothelial insulin uptake.
American journal of physiology. Endocrinology and metabolism300(1)E134-44(2011 Jan)
Wang H,Wang AX,Barrett EJ

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CAV1 cDNA ORF clone, Bos taurus(cattle)

Gene

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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