JUN cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	JUN
Entrez Gene ID	280831
Full Name	Jun proto-oncogene, AP-1 transcription factor subunit
General protein information	Preferred Names Jun proto-oncogene, AP-1 transcription factor subunit Names transcription factor AP-1 AP1 activator protein 1 jun oncogene proto-oncogene c-jun v-jun avian sarcoma virus 17 oncogene homolog
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001077827.1	NP_001071295.1	transcription factor AP-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	JUN	XP_513442.2
	JUN	XP_001114665.1
Gallus gallus (chicken)	JUN	NP_001026460.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006386	XP_001688864.1
Homo sapiens (human)	JUN	NP_002219.1
Bos taurus (cattle)	JUN	NP_001071295.1
Mus musculus (house mouse)	Jun	NP_034721.1
Rattus norvegicus (Norway rat)	Jun	NP_068607.1
Canis lupus familiaris (dog)	JUN	XP_005620302.1
Danio rerio (zebrafish)	jun	NP_956281.1
Xenopus tropicalis (tropical clawed frog)	jun	XP_002931634.1

Gene Ontology
Bibliography

Related articles in PubMed

The forkhead transcription factor FOXK2 promotes AP-1-mediated transcriptional regulation.
Ji Z, Donaldson IJ, Liu J, Hayes A, Zeef LA, Sharrocks AD
Molecular and cellular biology32(2)385-98(2012 Jan)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression.
Chowdhury TT, Salter DM, Bader DL, Lee DA
Inflammation research : official journal of the European Histamine Research Society ... [et al.]57(7)306-13(2008 Jul)

Bovine dialyzable leukocyte extract modulates AP-1 DNA-binding activity and nuclear transcription factor expression in MCF-7 breast cancer cells.
Mendoza-Gamboa E, Franco-Molina MA, Zapata-Benavides P, Castillo-Tello P, Vera-Garc?a ME, Tamez-Guerra RS, Rodr?guez-Padilla C
Cytotherapy10(2)212-9(2008)

Mechanisms of endothelial response to oxidative aggression: protective role of autologous VEGF and induction of VEGFR2 by H2O2.
Gonz?lez-Pacheco FR, Deudero JJ, Castellanos MC, Castilla MA, Alvarez-Arroyo MV, Yag?e S, Caramelo C
American journal of physiology. Heart and circulatory physiology291(3)H1395-401(2006 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

dynamic compression stimulates cell proliferation and proteoglycan synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 signalling pathways
Title: Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression.

The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 DNA-binding activity and expression of several transcriptions factors in breast cancer cells.
Title: Bovine dialyzable leukocyte extract modulates AP-1 DNA-binding activity and nuclear transcription factor expression in MCF-7 breast cancer cells.

The following JUN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JUN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa42520	NM_001077827.1 Latest version!	Bos taurus Jun proto-oncogene, AP-1 transcription factor subunit (JUN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JUN ( NM_001077827.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001071295.1 Bos taurus Jun proto-oncogene, AP-1 transcription factor subunit (JUN), mRNA.

Price & Availability↑

CloneID	OBa42520
Clone ID Related Accession (Same CDS sequence)	NM_001077827.1
Accession Version	NM_001077827.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Bos taurus(cattle)
Product	transcription factor AP-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC123753.1. On or before Nov 21, 2006 this sequence version replaced XM_593122.2, XM_864792.1, XM_874333.1. ##Evidence-Data-START## Transcript exon combination :: BC123753.1 [ECO:0000332] ##Evidence-Data-END##

ATGACTGCAA AGATGGAAAC GACCTTCTAC GACGATGCCC TCAACGCCTC GTTCCTCCAG 
TCTGAGAGCG GCGCCTACGG CTACAGTAAC CCCAAGATTC TGAAGCAGAG CATGACCCTG 
AATCTGGCCG ACCCGGTGGG CAGCCTGAAG CCGCACCTCC GGGCCAAGAA CTCCGACCTC 
CTCACCTCTC CCGACGTGGG GCTGCTCAAG CTGGCGTCGC CCGAGCTGGA GCGCCTAATC 
ATACAGTCCA GCAACGGGCA TATCACCACC ACGCCGACCC CTACCCAGTT CCTGTGCCCC 
AAGAACGTGA CGGACGAGCA GGAGGGATTC GCCGAGGGCT TCGTGCGCGC CCTGGCCGAA 
CTGCACAGCC AGAACACGCT GCCCAGCGTC ACGTCGGCGG CGCAGCCGGT CTACGCCAAC 
CTCAGCAACT TCAACCCCGG CTCGCTGAGC AGCGGCGGCG GGGCACCCTC CTACGGCGCG 
GCTGGCCTGG CCTTTCCCGC GCAGCCCCAG CAGCAGCAGC AGCAACCGCC GCAGCCGCCG 
CACCACCTGC CCCAGCAGAT CCCCGTGCAG CACCCGCGGC TGCAGGCCCT GAAGGAGGAG 
CCGCAGACGG TGCCCGAGAT GCCCGGGGAA ACGCCGCCCC TGTCCCCCAT CGACATGGAG 
TCCCAGGAGC GGATCAAGGC AGAGAGGAAG CGCATGAGGA ACCGCATCGC TGCCTCCAAG 
TGCCGGAAAA GGAAGCTGGA GAGGATCGCG CGGCTGGAGG AAAAAGTGAA AACCTTGAAA 
GCGCAGAACT CGGAGCTGGC GTCCACGGCC AATATGCTCA GGGAACAGGT GGCCCAGCTT 
AAACAGAAAG TCATGAACCA CGTTAACAGC GGGTGCCAAC TCATGCTAAC GCAGCAGTTG 
CAAACGTTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001071295.1
CDS	267..1178
Translation	MTAKMETTFYDDALNASFLQSESGAYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVYANLSNFNPGSLSSGGGAPSYGAAGLAFPAQPQQQQQQPPQPPHHLPQQIPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF

Target ORF information:

RefSeq Version	NM_001077827.1
Organism	Bos taurus(cattle)
Definition	Bos taurus Jun proto-oncogene, AP-1 transcription factor subunit (JUN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077827.1

ORF Insert Sequence:

ATGACTGCAA AGATGGAAAC GACCTTCTAC GACGATGCCC TCAACGCCTC GTTCCTCCAG 
TCTGAGAGCG GCGCCTACGG CTACAGTAAC CCCAAGATTC TGAAGCAGAG CATGACCCTG 
AATCTGGCCG ACCCGGTGGG CAGCCTGAAG CCGCACCTCC GGGCCAAGAA CTCCGACCTC 
CTCACCTCTC CCGACGTGGG GCTGCTCAAG CTGGCGTCGC CCGAGCTGGA GCGCCTAATC 
ATACAGTCCA GCAACGGGCA TATCACCACC ACGCCGACCC CTACCCAGTT CCTGTGCCCC 
AAGAACGTGA CGGACGAGCA GGAGGGATTC GCCGAGGGCT TCGTGCGCGC CCTGGCCGAA 
CTGCACAGCC AGAACACGCT GCCCAGCGTC ACGTCGGCGG CGCAGCCGGT CTACGCCAAC 
CTCAGCAACT TCAACCCCGG CTCGCTGAGC AGCGGCGGCG GGGCACCCTC CTACGGCGCG 
GCTGGCCTGG CCTTTCCCGC GCAGCCCCAG CAGCAGCAGC AGCAACCGCC GCAGCCGCCG 
CACCACCTGC CCCAGCAGAT CCCCGTGCAG CACCCGCGGC TGCAGGCCCT GAAGGAGGAG 
CCGCAGACGG TGCCCGAGAT GCCCGGGGAA ACGCCGCCCC TGTCCCCCAT CGACATGGAG 
TCCCAGGAGC GGATCAAGGC AGAGAGGAAG CGCATGAGGA ACCGCATCGC TGCCTCCAAG 
TGCCGGAAAA GGAAGCTGGA GAGGATCGCG CGGCTGGAGG AAAAAGTGAA AACCTTGAAA 
GCGCAGAACT CGGAGCTGGC GTCCACGGCC AATATGCTCA GGGAACAGGT GGCCCAGCTT 
AAACAGAAAG TCATGAACCA CGTTAACAGC GGGTGCCAAC TCATGCTAAC GCAGCAGTTG 
CAAACGTTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The forkhead transcription factor FOXK2 promotes AP-1-mediated transcriptional regulation.
Molecular and cellular biology32(2)385-98(2012 Jan)
Ji Z,Donaldson IJ,Liu J,Hayes A,Zeef LA,Sharrocks AD

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]57(7)306-13(2008 Jul)
Chowdhury TT,Salter DM,Bader DL,Lee DA

Bovine dialyzable leukocyte extract modulates AP-1 DNA-binding activity and nuclear transcription factor expression in MCF-7 breast cancer cells.
Cytotherapy10(2)212-9(2008)
Mendoza-Gamboa E,Franco-Molina MA,Zapata-Benavides P,Castillo-Tello P,Vera-Garc?a ME,Tamez-Guerra RS,Rodr?guez-Padilla C

Mechanisms of endothelial response to oxidative aggression: protective role of autologous VEGF and induction of VEGFR2 by H2O2.
American journal of physiology. Heart and circulatory physiology291(3)H1395-401(2006 Sep)
Gonz?lez-Pacheco FR,Deudero JJ,Castellanos MC,Castilla MA,Alvarez-Arroyo MV,Yag?e S,Caramelo C