| Gene Symbol | BGN |
| Entrez Gene ID | 280733 |
| Full Name | biglycan |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » BGN cDNA ORF clone
| Gene Symbol | BGN |
| Entrez Gene ID | 280733 |
| Full Name | biglycan |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Bos taurus(cattle) |
| mRNA | Protein | Name |
|---|---|---|
| XM_005227658.4 | XP_005227715.1 | biglycan isoform X1 |
| NM_178318.4 | NP_847888.2 | biglycan precursor |
| XM_005227658.3 | XP_005227715.1 | biglycan isoform X1 |
| Pan troglodytes (chimpanzee) | BGN | XP_529202.4 |
| Mus musculus (house mouse) | Bgn | NP_031568.2 |
| Homo sapiens (human) | BGN | NP_001702.1 |
| BGN | XP_001086112.2 | |
| Xenopus tropicalis (tropical clawed frog) | bgn | NP_001072552.1 |
| Danio rerio (zebrafish) | bgnb | NP_001001825.2 |
| Canis lupus familiaris (dog) | BGN | NP_001003229.1 |
| Bos taurus (cattle) | BGN | NP_847888.2 |
| Rattus norvegicus (Norway rat) | Bgn | NP_058783.1 |
Free axial vibrations at 0 to 200 Hz positively affect extracellular matrix messenger ribonucleic acid expression in bovine nucleus pulposi.
Desmoulin GT, Reno CR, Hunter CJ
Spine35(15)1437-44(2010 Jul)
The first draft of the endostatin interaction network.
Faye C, Chautard E, Olsen BR, Ricard-Blum S
The Journal of biological chemistry284(33)22041-7(2009 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Crystal structure of the biglycan dimer and evidence that dimerization is essential for folding and stability of class I small leucine-rich repeat proteoglycans.
Scott PG, Dodd CM, Bergmann EM, Sheehan JK, Bishop PN
The Journal of biological chemistry281(19)13324-32(2006 May)
Characterization of 954 bovine full-CDS cDNA sequences.
Harhay GP, Sonstegard TS, Keele JW, Heaton MP, Clawson ML, Snelling WM, Wiedmann RT, Van Tassell CP, Smith TP
BMC genomics6166(2005 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that biglycan, collagen type I, collagen type II, decorin, and versican were significantly affected by vibration duration, frequency, and amplitude.
Title: Free axial vibrations at 0 to 200 Hz positively affect extracellular matrix messenger ribonucleic acid expression in bovine nucleus pulposi.
The results indicate that CTGF suppresses the synthesis of biglycan but newly induced that of decorin in the cells when the cell density is low.
Title: Differential regulation of biglycan and decorin synthesis by connective tissue growth factor in cultured vascular endothelial cells.
biglycan-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration; potential role in the remodelling process
Title: Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration.
biglycan showed a unique ability to organize collagen VI into extensive hexagonal-like networks over a time period of only a few minutes
Title: Biglycan organizes collagen VI into hexagonal-like networks resembling tissue structures.
The following BGN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BGN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OBa00390 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005227658.4 , NM_178318.4 , XM_005227658.3 | |
| Accession Version | NM_178318.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Bos taurus(cattle) | |
| Product | biglycan precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC118460.1. On Aug 31, 2012 this sequence version replaced NM_178318.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC118460.1, BT021201.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTGGCCCC TGTGGCCTCT TGCAGCCCTG CTGGCCCTGA GCCAGGCCCT GCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_847888.2 |
| CDS | 98..1207 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_178318.4 |
1 | ATGTGGCCCC TGTGGCCTCT TGCAGCCCTG CTGGCCCTGA GCCAGGCCCT GCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OBa00390 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005227658.4 , NM_178318.4 , XM_005227658.3 | |
| Accession Version | XM_005227658.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-06 | |
| Organism | Bos taurus(cattle) | |
| Product | biglycan isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037357.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005227658.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGCCCC TGTGGCCTCT TGCAGCCCTG CTGGCCCTGA GCCAGGCCCT GCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005227715.1 |
| CDS | 245..1354 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005227658.4 |
1 | ATGTGGCCCC TGTGGCCTCT TGCAGCCCTG CTGGCCCTGA GCCAGGCCCT GCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OBa00390 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005227658.4 , NM_178318.4 , XM_005227658.3 | |
| Accession Version | XM_005227658.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-01-25 | |
| Organism | Bos taurus(cattle) | |
| Product | biglycan isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104686.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005227658.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGCCCC TGTGGCCTCT TGCAGCCCTG CTGGCCCTGA GCCAGGCCCT GCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005227715.1 |
| CDS | 252..1361 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005227658.3 |
1 | ATGTGGCCCC TGTGGCCTCT TGCAGCCCTG CTGGCCCTGA GCCAGGCCCT GCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Free axial vibrations at 0 to 200 Hz positively affect extracellular matrix messenger ribonucleic acid expression in bovine nucleus pulposi. |
The first draft of the endostatin interaction network. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Crystal structure of the biglycan dimer and evidence that dimerization is essential for folding and stability of class I small leucine-rich repeat proteoglycans. |
Characterization of 954 bovine full-CDS cDNA sequences. |