BAX cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	BAX
Entrez Gene ID	280730
Full Name	BCL2 associated X, apoptosis regulator
General protein information	Preferred Names BCL2 associated X, apoptosis regulator Names apoptosis regulator BAX BCL2-associated X protein
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_015458140.1	XP_015313626.1	apoptosis regulator BAX isoform X2
XM_015458140.2	XP_015313626.1	apoptosis regulator BAX isoform X2
NM_173894.1	NP_776319.1	apoptosis regulator BAX
XM_010814989.2	XP_010813291.1	apoptosis regulator BAX isoform X1
XM_010814989.3	XP_010813291.1	apoptosis regulator BAX isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BAX	NP_776319.1
Mus musculus (house mouse)	Bax	NP_031553.1
Xenopus tropicalis (tropical clawed frog)	bax	NP_989185.1
	BAX	XP_001112353.1
Danio rerio (zebrafish)	baxa	NP_571637.1
Homo sapiens (human)	BAX	NP_620116.1
Pan troglodytes (chimpanzee)	BAX	XP_001155879.2
Canis lupus familiaris (dog)	BAX	NP_001003011.1
Rattus norvegicus (Norway rat)	Bax	NP_058755.2

Gene Ontology
Bibliography

Related articles in PubMed

Bovine herpesvirus type 5 infection regulates Bax/BCL-2 ratio.
Garcia AF, Novais JB, Antello TF, Silva-Frade C, Ferrarezi MC, Flores EF, Cardoso TC
Genetics and molecular research : GMR12(3)3897-904(2013 Sep)

FasL-induced apoptosis in bovine oocytes via the Bax signal.
Li HJ, Wang CY, Mi Y, Du CG, Cao GF, Sun XC, Liu DJ, Shorgan B
Theriogenology80(3)248-55(2013 Aug)

Preimplantation development and expression of Hsp-70 and Bax genes in bovine blastocysts derived from oocytes matured in alpha-MEM supplemented with growth factors and synthetic macromolecules.
Vireque AA, Camargo LS, Serapi?o RV, Rosa E Silva AA, Watanabe YF, Ferreira EM, Navarro PA, Martins WP, Ferriani RA
Theriogenology71(4)620-7(2009 Mar)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

mRNA expression of Bcl-2, Bax, caspase-3 and -7 cannot be used as a marker for apoptosis in bovine blastocysts.
Vandaele L, Goossens K, Peelman L, Van Soom A
Animal reproduction science106(1-2)168-73(2008 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax expression.
Title: Bovine herpesvirus type 5 infection regulates Bax/BCL-2 ratio.

It was concluded that the Fas-FasL signaling pathway was involved in regulation of bovine oocyte apoptosis, perhaps related to B cell lymphoma/leukemia-2 associated X upregulation.
Title: FasL-induced apoptosis in bovine oocytes via the Bax signal.

The effect of culture conditions on expression of heat shock protein 70 and Bax protein in bovine blastocysts is reported.
Title: Preimplantation development and expression of Hsp-70 and Bax genes in bovine blastocysts derived from oocytes matured in alpha-MEM supplemented with growth factors and synthetic macromolecules.

mRNA expression of Bax, Bcl-2, caspase-3 and-7 cannot be used as a reliable apoptosis detection method.
Title: mRNA expression of Bcl-2, Bax, caspase-3 and -7 cannot be used as a marker for apoptosis in bovine blastocysts.

apoptosis-inducing factor was expressed in luminal alveolar cells and, in concert with a change in bax protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses
Title: Functional expression of bcl-2 protein family and AIF in bovine mammary tissue in early lactation.

The following BAX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BAX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa14293	NM_173894.1 Latest version!	Bos taurus BCL2 associated X, apoptosis regulator (BAX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa44990	XM_010814989.3 Latest version!	Bos taurus BCL2 associated X, apoptosis regulator (BAX), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa93479	XM_015458140.2 Latest version!	Bos taurus BCL2 associated X, apoptosis regulator (BAX), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
View Old Accession Versions >>
OBa93479	XM_015458140.1	Bos taurus BCL2-associated X protein (BAX), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
OBa44990	XM_010814989.2	Bos taurus BCL2-associated X protein (BAX), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BAX ( NM_173894.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776319.1 Bos taurus BCL2 associated X, apoptosis regulator (BAX), mRNA.

Price & Availability↑

CloneID	OBa14293
Clone ID Related Accession (Same CDS sequence)	NM_173894.1
Accession Version	NM_173894.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Bos taurus(cattle)
Product	apoptosis regulator BAX
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U92569.1. ##Evidence-Data-START## Transcript exon combination :: U92569.1, DN286069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END##

ATGGACGGGT CCGGGGAGCA ACCCAGAGGC GGGGGGCCCA CCAGCTCTGA GCAGATCATG 
AAGACAGGGG CCCTTTTGCT TCAGGGTTTC ATCCAGGATC GAGCAGGGCG AATGGGGGGA 
GAGACACCCG AGCTGGGCTT GGAGCAGGTG CCCCAGGATG CATCCACCAA GAAGCTGAGC 
GAGTGTCTGA AGCGCATCGG AGATGAATTG GACAGTAACA TGGAGCTGCA GAGGATGATC 
GCAGCTGTGG ACACAGACTC TCCCCGAGAG GTCTTTTTCC GAGTGGCGGC TGAAATGTTT 
TCTGACGGCA ACTTCAACTG GGGCCGGGTT GTCGCCCTTT TCTACTTTGC CAGCAAACTG 
GTGCTCAAGG CCCTGTGCAC CAAGGTGCCC GAGTTGATCA GGACCATCAT GGGCTGGACA 
TTGGACTTCC TTCGAGAGCG GCTGCTGGGC TGGATCCAGG ACCAGGGTGG TTGGGACGGC 
CTCCTCTCCT ACTTTGGGAC ACCCACATGG CAGACAGTGA CCATCTTTGT GGCTGGAGTG 
CTCACCGCCT CGCTCACCAT CTGGAAGAAG ATGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776319.1
CDS	1..579
Translation	MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGETPELGLEQVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAAEMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG

Target ORF information:

RefSeq Version	NM_173894.1
Organism	Bos taurus(cattle)
Definition	Bos taurus BCL2 associated X, apoptosis regulator (BAX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173894.1

ORF Insert Sequence:

ATGGACGGGT CCGGGGAGCA ACCCAGAGGC GGGGGGCCCA CCAGCTCTGA GCAGATCATG 
AAGACAGGGG CCCTTTTGCT TCAGGGTTTC ATCCAGGATC GAGCAGGGCG AATGGGGGGA 
GAGACACCCG AGCTGGGCTT GGAGCAGGTG CCCCAGGATG CATCCACCAA GAAGCTGAGC 
GAGTGTCTGA AGCGCATCGG AGATGAATTG GACAGTAACA TGGAGCTGCA GAGGATGATC 
GCAGCTGTGG ACACAGACTC TCCCCGAGAG GTCTTTTTCC GAGTGGCGGC TGAAATGTTT 
TCTGACGGCA ACTTCAACTG GGGCCGGGTT GTCGCCCTTT TCTACTTTGC CAGCAAACTG 
GTGCTCAAGG CCCTGTGCAC CAAGGTGCCC GAGTTGATCA GGACCATCAT GGGCTGGACA 
TTGGACTTCC TTCGAGAGCG GCTGCTGGGC TGGATCCAGG ACCAGGGTGG TTGGGACGGC 
CTCCTCTCCT ACTTTGGGAC ACCCACATGG CAGACAGTGA CCATCTTTGT GGCTGGAGTG 
CTCACCGCCT CGCTCACCAT CTGGAAGAAG ATGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BAX ( XM_010814989.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010813291.1 Bos taurus BCL2-associated X protein (BAX), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa44990
Clone ID Related Accession (Same CDS sequence)	XM_010814989.2 , XM_010814989.3
Accession Version	XM_010814989.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	apoptosis regulator BAX isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104466.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_010814989.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGGAG AGACACCCGA GCTGGGCTTG GAGCAGGTGC CCCAGGATGC ATCCACCAAG 
AAGCTGAGCG AGTGTCTGAA GCGCATCGGA GATGAATTGG ACAGTAACAT GGAGCTGCAG 
AGGATGATCG CAGCTGTGGA CACAGACTCT CCCCGAGAGG TCTTTTTCCG AGTGGCGGCT 
GAAATGTTTT CTGACGGCAA CTTCAACTGG GGCCGGGTTG TCGCCCTTTT CTACTTTGCC 
AGCAAACTGG TGCTCAAGGC CCTGTGCACC AAGGTGCCCG AGTTGATCAG GACCATCATG 
GGCTGGACAT TGGACTTCCT TCGAGAGCGG CTGCTGGGCT GGATCCAGGA CCAGGGTGGT 
TGGGACGGCC TCCTCTCCTA CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG 
GCTGGAGTGC TCACCGCCTC GCTCACCATC TGGAAGAAGA TGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010813291.1
CDS	107..574
Translation	MGGETPELGLEQVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAAEMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG

Target ORF information:

RefSeq Version	XM_010814989.2
Organism	Bos taurus(cattle)
Definition	Bos taurus BCL2-associated X protein (BAX), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010814989.2

ORF Insert Sequence:

ATGGGGGGAG AGACACCCGA GCTGGGCTTG GAGCAGGTGC CCCAGGATGC ATCCACCAAG 
AAGCTGAGCG AGTGTCTGAA GCGCATCGGA GATGAATTGG ACAGTAACAT GGAGCTGCAG 
AGGATGATCG CAGCTGTGGA CACAGACTCT CCCCGAGAGG TCTTTTTCCG AGTGGCGGCT 
GAAATGTTTT CTGACGGCAA CTTCAACTGG GGCCGGGTTG TCGCCCTTTT CTACTTTGCC 
AGCAAACTGG TGCTCAAGGC CCTGTGCACC AAGGTGCCCG AGTTGATCAG GACCATCATG 
GGCTGGACAT TGGACTTCCT TCGAGAGCGG CTGCTGGGCT GGATCCAGGA CCAGGGTGGT 
TGGGACGGCC TCCTCTCCTA CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG 
GCTGGAGTGC TCACCGCCTC GCTCACCATC TGGAAGAAGA TGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BAX ( XM_010814989.3 ) cDNA ORF clone, Bos taurus(cattle) -> XP_010813291.1 Bos taurus BCL2 associated X, apoptosis regulator (BAX), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa44990
Clone ID Related Accession (Same CDS sequence)	XM_010814989.2 , XM_010814989.3
Accession Version	XM_010814989.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	apoptosis regulator BAX isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037345.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_010814989.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGGAG AGACACCCGA GCTGGGCTTG GAGCAGGTGC CCCAGGATGC ATCCACCAAG 
AAGCTGAGCG AGTGTCTGAA GCGCATCGGA GATGAATTGG ACAGTAACAT GGAGCTGCAG 
AGGATGATCG CAGCTGTGGA CACAGACTCT CCCCGAGAGG TCTTTTTCCG AGTGGCGGCT 
GAAATGTTTT CTGACGGCAA CTTCAACTGG GGCCGGGTTG TCGCCCTTTT CTACTTTGCC 
AGCAAACTGG TGCTCAAGGC CCTGTGCACC AAGGTGCCCG AGTTGATCAG GACCATCATG 
GGCTGGACAT TGGACTTCCT TCGAGAGCGG CTGCTGGGCT GGATCCAGGA CCAGGGTGGT 
TGGGACGGCC TCCTCTCCTA CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG 
GCTGGAGTGC TCACCGCCTC GCTCACCATC TGGAAGAAGA TGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_010813291.1
CDS	142..609
Translation	MGGETPELGLEQVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAAEMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG

Target ORF information:

RefSeq Version	XM_010814989.3
Organism	Bos taurus(cattle)
Definition	Bos taurus BCL2 associated X, apoptosis regulator (BAX), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_010814989.3

ORF Insert Sequence:

ATGGGGGGAG AGACACCCGA GCTGGGCTTG GAGCAGGTGC CCCAGGATGC ATCCACCAAG 
AAGCTGAGCG AGTGTCTGAA GCGCATCGGA GATGAATTGG ACAGTAACAT GGAGCTGCAG 
AGGATGATCG CAGCTGTGGA CACAGACTCT CCCCGAGAGG TCTTTTTCCG AGTGGCGGCT 
GAAATGTTTT CTGACGGCAA CTTCAACTGG GGCCGGGTTG TCGCCCTTTT CTACTTTGCC 
AGCAAACTGG TGCTCAAGGC CCTGTGCACC AAGGTGCCCG AGTTGATCAG GACCATCATG 
GGCTGGACAT TGGACTTCCT TCGAGAGCGG CTGCTGGGCT GGATCCAGGA CCAGGGTGGT 
TGGGACGGCC TCCTCTCCTA CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG 
GCTGGAGTGC TCACCGCCTC GCTCACCATC TGGAAGAAGA TGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BAX ( XM_015458140.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_015313626.1 Bos taurus BCL2-associated X protein (BAX), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa93479
Clone ID Related Accession (Same CDS sequence)	XM_015458140.1 , XM_015458140.2
Accession Version	XM_015458140.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-25
Organism	Bos taurus(cattle)
Product	apoptosis regulator BAX isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104466.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGGGT CCGGGGAGCA ACCCAGAGGC GGGGGGCCCA CCAGCTCTGA GCAGATCATG 
AAGACAGGGG CCCTTTTGCT TCAGGGTTTC ATCCAGGATC GAGCAGGGCG AATGGGGGGA 
GAGACACCCG AGCTGGGCTT GGAGCAGGTG CCCCAGGATG CATCCACCAA GAAGCTGAGC 
GAGTGTCTGA AGCGCATCGG AGATGAATTG GACAGTAACA TGGAGCTGCA GAGGATGATC 
GCAGCTGTGG ACACAGACTC TCCCCGAGAG GTCTTTTTCC GAGTGGCGGC TGAAATGTTT 
TCTGACGGCA ACTTCAACTG GGGCCGGGTT GTCGCCCTTT TCTACTTTGC CAGCAAACTG 
GTGCTCAAGG CCCTGTGCAC CAAGGTGCCC GAGTTGATCA GGACCATCAT GGGCTGGACA 
TTGGACTTCC TTCGAGAGCG GCTGCTGGGC TGGATCCAGG ACCAGGGTGG TTGGGGCTGC 
CCCTTGGCTG AGTCGCTGAA GTGCCTGCTG TCCCTATCCC CAGGACGGCC TCCTCTCCTA 
CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG GCTGGAGTGC TCACCGCCTC 
GCTCACCATC TGGAAGAAGA TGGGCTGAGG CCATCAACTG CCTTGGACTT TTTCTGCATA 
AATTATGGCA TTTTTCAGGG GGGTGGGGCG GATTTGGGGG CCATGGAGTT TTTCTTACTT 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015313626.1
CDS	62..787
Translation	MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGETPELGLEQVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAAEMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWGCPLAESLKCLLSLSPGRPPLLLWDTHMADSDHLCGWSAHRLAHHLEEDGLRPSTALDFFCINYGIFQGGGADLGAMEFFLLF

Target ORF information:

RefSeq Version	XM_015458140.1
Organism	Bos taurus(cattle)
Definition	Bos taurus BCL2-associated X protein (BAX), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015458140.1

ORF Insert Sequence:

ATGGACGGGT CCGGGGAGCA ACCCAGAGGC GGGGGGCCCA CCAGCTCTGA GCAGATCATG 
AAGACAGGGG CCCTTTTGCT TCAGGGTTTC ATCCAGGATC GAGCAGGGCG AATGGGGGGA 
GAGACACCCG AGCTGGGCTT GGAGCAGGTG CCCCAGGATG CATCCACCAA GAAGCTGAGC 
GAGTGTCTGA AGCGCATCGG AGATGAATTG GACAGTAACA TGGAGCTGCA GAGGATGATC 
GCAGCTGTGG ACACAGACTC TCCCCGAGAG GTCTTTTTCC GAGTGGCGGC TGAAATGTTT 
TCTGACGGCA ACTTCAACTG GGGCCGGGTT GTCGCCCTTT TCTACTTTGC CAGCAAACTG 
GTGCTCAAGG CCCTGTGCAC CAAGGTGCCC GAGTTGATCA GGACCATCAT GGGCTGGACA 
TTGGACTTCC TTCGAGAGCG GCTGCTGGGC TGGATCCAGG ACCAGGGTGG TTGGGGCTGC 
CCCTTGGCTG AGTCGCTGAA GTGCCTGCTG TCCCTATCCC CAGGACGGCC TCCTCTCCTA 
CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG GCTGGAGTGC TCACCGCCTC 
GCTCACCATC TGGAAGAAGA TGGGCTGAGG CCATCAACTG CCTTGGACTT TTTCTGCATA 
AATTATGGCA TTTTTCAGGG GGGTGGGGCG GATTTGGGGG CCATGGAGTT TTTCTTACTT 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BAX ( XM_015458140.2 ) cDNA ORF clone, Bos taurus(cattle) -> XP_015313626.1 Bos taurus BCL2 associated X, apoptosis regulator (BAX), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OBa93479
Clone ID Related Accession (Same CDS sequence)	XM_015458140.1 , XM_015458140.2
Accession Version	XM_015458140.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	apoptosis regulator BAX isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037345.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_015458140.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGGGT CCGGGGAGCA ACCCAGAGGC GGGGGGCCCA CCAGCTCTGA GCAGATCATG 
AAGACAGGGG CCCTTTTGCT TCAGGGTTTC ATCCAGGATC GAGCAGGGCG AATGGGGGGA 
GAGACACCCG AGCTGGGCTT GGAGCAGGTG CCCCAGGATG CATCCACCAA GAAGCTGAGC 
GAGTGTCTGA AGCGCATCGG AGATGAATTG GACAGTAACA TGGAGCTGCA GAGGATGATC 
GCAGCTGTGG ACACAGACTC TCCCCGAGAG GTCTTTTTCC GAGTGGCGGC TGAAATGTTT 
TCTGACGGCA ACTTCAACTG GGGCCGGGTT GTCGCCCTTT TCTACTTTGC CAGCAAACTG 
GTGCTCAAGG CCCTGTGCAC CAAGGTGCCC GAGTTGATCA GGACCATCAT GGGCTGGACA 
TTGGACTTCC TTCGAGAGCG GCTGCTGGGC TGGATCCAGG ACCAGGGTGG TTGGGGCTGC 
CCCTTGGCTG AGTCGCTGAA GTGCCTGCTG TCCCTATCCC CAGGACGGCC TCCTCTCCTA 
CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG GCTGGAGTGC TCACCGCCTC 
GCTCACCATC TGGAAGAAGA TGGGCTGAGG CCATCAACTG CCTTGGACTT TTTCTGCATA 
AATTATGGCA TTTTTCAGGG GGGTGGGGCG GATTTGGGGG CCATGGAGTT TTTCTTACTT 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015313626.1
CDS	90..815
Translation	MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGETPELGLEQVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAAEMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWGCPLAESLKCLLSLSPGRPPLLLWDTHMADSDHLCGWSAHRLAHHLEEDGLRPSTALDFFCINYGIFQGGGADLGAMEFFLLF

Target ORF information:

RefSeq Version	XM_015458140.2
Organism	Bos taurus(cattle)
Definition	Bos taurus BCL2 associated X, apoptosis regulator (BAX), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015458140.2

ORF Insert Sequence:

ATGGACGGGT CCGGGGAGCA ACCCAGAGGC GGGGGGCCCA CCAGCTCTGA GCAGATCATG 
AAGACAGGGG CCCTTTTGCT TCAGGGTTTC ATCCAGGATC GAGCAGGGCG AATGGGGGGA 
GAGACACCCG AGCTGGGCTT GGAGCAGGTG CCCCAGGATG CATCCACCAA GAAGCTGAGC 
GAGTGTCTGA AGCGCATCGG AGATGAATTG GACAGTAACA TGGAGCTGCA GAGGATGATC 
GCAGCTGTGG ACACAGACTC TCCCCGAGAG GTCTTTTTCC GAGTGGCGGC TGAAATGTTT 
TCTGACGGCA ACTTCAACTG GGGCCGGGTT GTCGCCCTTT TCTACTTTGC CAGCAAACTG 
GTGCTCAAGG CCCTGTGCAC CAAGGTGCCC GAGTTGATCA GGACCATCAT GGGCTGGACA 
TTGGACTTCC TTCGAGAGCG GCTGCTGGGC TGGATCCAGG ACCAGGGTGG TTGGGGCTGC 
CCCTTGGCTG AGTCGCTGAA GTGCCTGCTG TCCCTATCCC CAGGACGGCC TCCTCTCCTA 
CTTTGGGACA CCCACATGGC AGACAGTGAC CATCTTTGTG GCTGGAGTGC TCACCGCCTC 
GCTCACCATC TGGAAGAAGA TGGGCTGAGG CCATCAACTG CCTTGGACTT TTTCTGCATA 
AATTATGGCA TTTTTCAGGG GGGTGGGGCG GATTTGGGGG CCATGGAGTT TTTCTTACTT 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bovine herpesvirus type 5 infection regulates Bax/BCL-2 ratio.
Genetics and molecular research : GMR12(3)3897-904(2013 Sep)
Garcia AF,Novais JB,Antello TF,Silva-Frade C,Ferrarezi MC,Flores EF,Cardoso TC

FasL-induced apoptosis in bovine oocytes via the Bax signal.
Theriogenology80(3)248-55(2013 Aug)
Li HJ,Wang CY,Mi Y,Du CG,Cao GF,Sun XC,Liu DJ,Shorgan B

Preimplantation development and expression of Hsp-70 and Bax genes in bovine blastocysts derived from oocytes matured in alpha-MEM supplemented with growth factors and synthetic macromolecules.
Theriogenology71(4)620-7(2009 Mar)
Vireque AA,Camargo LS,Serapi?o RV,Rosa E Silva AA,Watanabe YF,Ferreira EM,Navarro PA,Martins WP,Ferriani RA

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

mRNA expression of Bcl-2, Bax, caspase-3 and -7 cannot be used as a marker for apoptosis in bovine blastocysts.
Animal reproduction science106(1-2)168-73(2008 Jun)
Vandaele L,Goossens K,Peelman L,Van Soom A

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BAX cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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