Gene Symbol | HP |
Entrez Gene ID | 280692 |
Full Name | haptoglobin |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » HP cDNA ORF clone
Gene Symbol | HP |
Entrez Gene ID | 280692 |
Full Name | haptoglobin |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_001040470.2 | NP_001035560.1 | haptoglobin precursor |
The concentrations of inflammatory cytokines and acute-phase proteins in the peripheral blood and uterine washings in cows with pyometra.
Brodzki P, Kostro K, Brodzki A, Zi?tek J
Reproduction in domestic animals = Zuchthygiene50(3)417-22(2015 Jun)
Characterization of the contributions of Hp-MMP 9 to the serum acute phase protein response of lipopolysaccharide challenged calves.
Hinds CA, Niehaus AJ, Premanandan C, Rajala-Schultz PJ, Rings DM, Lakritz J
BMC veterinary research10261(2014 Oct)
Serum amyloid A and haptoglobin concentrations and liver fat percentage in lactating dairy cows with abomasal displacement.
Guzelbektes H, Sen I, Ok M, Constable PD, Boydak M, Coskun A
Journal of veterinary internal medicine24(1)213-9(2010 Jan-Feb)
Neutrophils as one of the major haptoglobin sources in mastitis affected milk.
Lai IH, Tsao JH, Lu YP, Lee JW, Zhao X, Chien FL, Mao SJ
Veterinary research40(3)17(2009 May-Jun)
Haptoglobin comprises about 10% of granule protein extracted from bovine granulocytes isolated from healthy cattle.
Cooray R, Waller KP, Venge P
Veterinary immunology and immunopathology119(3-4)310-5(2007 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results indicate that it is possible to monitor the course of pyometra in cows based on the evaluation of the concentration of cytokines and Hp in the serum and uterine washings.
Title: The concentrations of inflammatory cytokines and acute-phase proteins in the peripheral blood and uterine washings in cows with pyometra.
These data demonstrate that serum neutrophil haptoglobin-MMP 9 complexes appear sooner and decline more rapidly than other acute phase proteins.
Title: Characterization of the contributions of Hp-MMP 9 to the serum acute phase protein response of lipopolysaccharide challenged calves.
An increase in serum amyloid A or haptoglobin in dairy cows with abomasal displacementis not specific for inflammation or bacterial infection; increased levels of either may indicate the presence of hepatic lipidosis.
Title: Serum amyloid A and haptoglobin concentrations and liver fat percentage in lactating dairy cows with abomasal displacement.
This study suggests that neutrophils and epithelial cells may play an essential role in elevating milk haptoglobin (Hp) in addition to previous suggestions that Hp may be derived from mammary tissues and circulation.
Title: Neutrophils as one of the major haptoglobin sources in mastitis affected milk.
Bovine granulocytes, isolated from peripheral blood of healthy cattle, contain abundant amounts of haptoglobin within the granules.
Title: Haptoglobin comprises about 10% of granule protein extracted from bovine granulocytes isolated from healthy cattle.
The following HP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa00230 | |
Clone ID Related Accession (Same CDS sequence) | NM_001040470.2 | |
Accession Version | NM_001040470.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1206bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | haptoglobin precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC109668.1. On Aug 31, 2012 this sequence version replaced NM_001040470.1. ##Evidence-Data-START## Transcript exon combination :: BC109668.1, DR713114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05861934 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGCGCCC TGCAAGCTGT CGTCACTCTC CTGCTCTGCG GGCAGCTTCT CGCGGTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001035560.1 |
CDS | 31..1236 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001040470.2 |
1 | ATGAGCGCCC TGCAAGCTGT CGTCACTCTC CTGCTCTGCG GGCAGCTTCT CGCGGTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The concentrations of inflammatory cytokines and acute-phase proteins in the peripheral blood and uterine washings in cows with pyometra. |
Characterization of the contributions of Hp-MMP 9 to the serum acute phase protein response of lipopolysaccharide challenged calves. |
Serum amyloid A and haptoglobin concentrations and liver fat percentage in lactating dairy cows with abomasal displacement. |
Neutrophils as one of the major haptoglobin sources in mastitis affected milk. |
Haptoglobin comprises about 10% of granule protein extracted from bovine granulocytes isolated from healthy cattle. |