| Gene Symbol | C4A |
| Entrez Gene ID | 280678 |
| Full Name | complement component 4A |
| Synonyms | C4 |
| Gene Type | protein-coding |
| Organism | Bos taurus(cattle) |
gRNAs
The following C4A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C4A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OBa229397 | |
| Clone ID Related Accession (Same CDS sequence) | XM_024983371.1 | |
| Accession Version | XM_024983371.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4230bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-06 | |
| Organism | Bos taurus(cattle) | |
| Product | complement C4 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037350.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAGGCTCC TCTGGGGGCT GATCTGGGCA TCTTGCTTCT TCGCCTTGTC TCTGCAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_024839139.1 |
| CDS | 75..4304 |
| Translation |
Target ORF information:
Target ORF information:
|
 XM_024983371.1 |
1 | ATGAGGCTCC TCTGGGGGCT GATCTGGGCA TCTTGCTTCT TCGCCTTGTC TCTGCAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OBa229398 | |
| Clone ID Related Accession (Same CDS sequence) | XM_024983372.1 | |
| Accession Version | XM_024983372.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4194bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-06 | |
| Organism | Bos taurus(cattle) | |
| Product | complement C4 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037350.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCCAGTG CCAAATTTCC CTGCAAAAGG CTGAGTTTCA GGGTGTGCTG GAGAAGCTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_024839140.1 |
| CDS | 959..5152 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_024983372.1 |
1 | ATGGCCAGTG CCAAATTTCC CTGCAAAAGG CTGAGTTTCA GGGTGTGCTG GAGAAGCTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OBa44444 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001166485.1 | |
| Accession Version | NM_001166485.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5226bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-22 | |
| Organism | Bos taurus(cattle) | |
| Product | complement C4 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from NKLS02000023.1. On Oct 24, 2009 this sequence version replaced XM_584742.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5571260.44085.1, SRR5571260.49140.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGAGGCTCC TCTGGGGGCT GATCTGGGCA TCTTGCTTCT TCGCCTTGTC TCTGCAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001159957.1 |
| CDS | 37..5262 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001166485.1 |
1 | ATGAGGCTCC TCTGGGGGCT GATCTGGGCA TCTTGCTTCT TCGCCTTGTC TCTGCAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Increased expression of a novel splice variant of the complement component 4 (C4A) gene in mastitis-infected dairy cattle. |
Three novel single-nucleotide polymorphisms of complement component 4 gene (C4A) in Chinese Holstein cattle and their associations with milk performance traits and CH50. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Primary structure of bovine complement activation fragment C4a, the third anaphylatoxin. Purification and complete amino acid sequence. |
