CSN5A cDNA ORF clone, Arabidopsis thaliana(thale cress)

Gene
Clones
gRNAs

Summary

Gene Symbol	CSN5A
Entrez Gene ID	838899
Full Name	COP9 signalosome 5A
Synonyms	AJH1,ARABIDOPSIS JAB1 HOMOLOG 1,COP9 signalosome 5A,CSN5,F19G10.12,F19G10_12,JAB1,PUTATIVE JUN KINASE ACTIVATOR
Gene Type	protein-coding
Organism	Arabidopsis thaliana(thale cress)

mRNA and Protein(s)

mRNA	Protein	Name
NM_202161.1	NP_973890.1	COP9 signalosome 5A
NM_102139.2	NP_173705.1	COP9 signalosome 5A

Pathways from BioSystems

Homologies

Homo sapiens (human)	COPS5	NP_006828.2
Bos taurus (cattle)	COPS5	NP_001179068.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002880	XP_312032.5
Mus musculus (house mouse)	Cops5	NP_038743.1
Arabidopsis thaliana (thale cress)	CSN5B	NP_177279.1
Oryza sativa (rice)	Os04g0654700	NP_001054112.1
Xenopus tropicalis (tropical clawed frog)	cops5	NP_989109.1
Pan troglodytes (chimpanzee)	COPS5	XP_001162723.1
Canis lupus familiaris (dog)	COPS5	XP_005638087.1
Gallus gallus (chicken)	COPS5	NP_001034400.1
Drosophila melanogaster (fruit fly)	CSN5	NP_477442.1
Caenorhabditis elegans (roundworm)	csn-5	NP_500841.1
Magnaporthe oryzae (rice blast fungus)	MGG_05274	XP_003712833.1
Neurospora crassa	NCU00467	XP_956786.1
	COPS5	XP_001097856.1
Rattus norvegicus (Norway rat)	Cops5	NP_001020866.1
Danio rerio (zebrafish)	cops5	NP_957019.1
Arabidopsis thaliana (thale cress)	CSN5A	NP_173705.1

Gene Ontology
Bibliography

Related articles in PubMed

Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.
Theologis A, Ecker JR, Palm CJ, Federspiel NA, Kaul S, White O, Alonso J, Altafi H, Araujo R, Bowman CL, Brooks SY, Buehler E, Chan A, Chao Q, Chen H, Cheuk RF, Chin CW, Chung MK, Conn L, Conway AB, Conway AR, Creasy TH, Dewar K, Dunn P, Etgu P, Feldblyum TV, Feng J, Fong B, Fujii CY, Gill JE, Goldsmith AD, Haas B, Hansen NF, Hughes B, Huizar L, Hunter JL, Jenkins J, Johnson-Hopson C, Khan S, Khaykin E, Kim CJ, Koo HL, Kremenetskaia I, Kurtz DB, Kwan A, Lam B, Langin-Hooper S, Lee A, Lee JM, Lenz CA, Li JH, Li Y, Lin X, Liu SX, Liu ZA, Luros JS, Maiti R, Marziali A, Militscher J, Miranda M, Nguyen M, Nierman WC, Osborne BI, Pai G, Peterson J, Pham PK, Rizzo M, Rooney T, Rowley D, Sakano H, Salzberg SL, Schwartz JR, Shinn P, Southwick AM, Sun H, Tallon LJ, Tambunga G, Toriumi MJ, Town CD, Utterback T, Van Aken S, Vaysberg M, Vysotskaia VS, Walker M, Wu D, Yu G, Fraser CM, Venter JC, Davis RW
Nature408(6814)816-20(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings indicate that the rescue of csn5a-2 resulted from a trans T-DNA-mediated epigenetic effect on the csn5a-2 intronic T-DNA.
Title: Instability of the Arabidopsis mutant csn5a-2 caused by epigenetic modification of intronic T-DNA.

The organization of a CSN5-containing subcomplex of the COP9 signalosome.
Title: The organization of a CSN5-containing subcomplex of the COP9 signalosome.

Data suggest that Arabidopsis csn mutants undergo DNA damage, which might be the cause of the delay in G2 cell cycle progression.
Title: The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.

Results indicate that although CSN6A and CSN6B retain mostly redundant functions, CSN5A and CSN5B play unequal roles in the regulation of plant development.
Title: Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases.

The cop/det/fus mutant phenotype may be the result of the defects caused by impaired CSN5-dependent deneddylation of cullin-containing E3s.
Title: Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis.

The following CSN5A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSN5A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OAb24282	NM_102139.2 Latest version!	Arabidopsis thaliana COP9 signalosome 5A (CSN5A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OAb24283	NM_202161.1 Latest version!	Arabidopsis thaliana COP9 signalosome 5A (CSN5A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CSN5A ( NM_102139.2 ) cDNA ORF clone, Arabidopsis thaliana(thale cress) -> NP_173705.1 Arabidopsis thaliana COP9 signalosome 5A (CSN5A), mRNA.

Price & Availability↑

CloneID	OAb24282
Clone ID Related Accession (Same CDS sequence)	NM_102139.2
Accession Version	NM_102139.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-13
Organism	Arabidopsis thaliana(thale cress)
Product	COP9 signalosome 5A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003070). On Sep 12, 2016 this sequence version replaced NM_102139.1.

ATGGAAGGTT CCTCGTCAGC CATCGCGAGG AAGACATGGG AGCTAGAGAA CAACATTCTC 
CCAGTGGAAC CAACCGATTC AGCCTCCGAC AGTATATTCC ACTACGACGA CGCTTCACAA 
GCCAAAATCC AGCAGGAGAA GCCATGGGCC TCCGATCCTA ACTACTTCAA GCGCGTTCAC 
ATCTCAGCCC TTGCTCTTCT CAAGATGGTG GTTCACGCTC GCTCCGGTGG CACAATCGAG 
ATCATGGGTC TTATGCAGGG TAAAACCGAG GGTGATACAA TCATCGTTAT GGATGCTTTT 
GCTTTGCCTG TTGAAGGTAC TGAGACTAGG GTTAATGCTC AGTCTGATGC CTATGAGTAT 
ATGGTTGAAT ACTCTCAGAC CAGCAAGCTG GCTGGGAGGT TGGAGAACGT TGTTGGATGG 
TATCACTCTC ACCCTGGGTA TGGATGTTGG CTCTCGGGTA TTGATGTTTC GACACAGATG 
CTTAACCAAC AGTATCAGGA GCCATTCTTA GCTGTTGTTA TTGATCCAAC AAGGACTGTT 
TCGGCTGGTA AGGTTGAGAT TGGGGCATTC AGAACATATC CAGAGGGACA TAAGATCTCG 
GATGATCATG TTTCTGAGTA TCAGACTATC CCTCTTAACA AGATTGAGGA CTTTGGTGTA 
CATTGCAAAC AGTACTACTC ATTGGACATC ACTTATTTCA AGTCATCTCT CGATAGTCAC 
CTTCTGGATC TCCTTTGGAA CAAGTACTGG GTGAACACTC TTTCTTCTTC CCCACTGTTG 
GGCAATGGAG ACTATGTTGC CGGGCAAATA TCAGACTTGG CTGAGAAGCT CGAGCAAGCG 
GAGAGTCAGC TCGCTAACTC CCGGTATGGA GGAATTGCGC CAGCCGGTCA CCAAAGGAGG 
AAAGAGGATG AGCCTCAACT CGCGAAGATA ACTCGGGATA GTGCAAAGAT AACTGTCGAG 
CAGGTCCATG GACTAATGTC ACAGGTTATC AAAGACATCT TGTTCAATTC CGCTCGTCAG 
TCCAAGAAGT CTGCTGACGA CTCATCAGAT CCAGAGCCCA TGATTACATC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_173705.1
CDS	167..1240
Translation	MEGSSSAIARKTWELENNILPVEPTDSASDSIFHYDDASQAKIQQEKPWASDPNYFKRVHISALALLKMVVHARSGGTIEIMGLMQGKTEGDTIIVMDAFALPVEGTETRVNAQSDAYEYMVEYSQTSKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQMLNQQYQEPFLAVVIDPTRTVSAGKVEIGAFRTYPEGHKISDDHVSEYQTIPLNKIEDFGVHCKQYYSLDITYFKSSLDSHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQAESQLANSRYGGIAPAGHQRRKEDEPQLAKITRDSAKITVEQVHGLMSQVIKDILFNSARQSKKSADDSSDPEPMITS

Target ORF information:

RefSeq Version	NM_102139.2
Organism	Arabidopsis thaliana(thale cress)
Definition	Arabidopsis thaliana COP9 signalosome 5A (CSN5A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_102139.2

ORF Insert Sequence:

ATGGAAGGTT CCTCGTCAGC CATCGCGAGG AAGACATGGG AGCTAGAGAA CAACATTCTC 
CCAGTGGAAC CAACCGATTC AGCCTCCGAC AGTATATTCC ACTACGACGA CGCTTCACAA 
GCCAAAATCC AGCAGGAGAA GCCATGGGCC TCCGATCCTA ACTACTTCAA GCGCGTTCAC 
ATCTCAGCCC TTGCTCTTCT CAAGATGGTG GTTCACGCTC GCTCCGGTGG CACAATCGAG 
ATCATGGGTC TTATGCAGGG TAAAACCGAG GGTGATACAA TCATCGTTAT GGATGCTTTT 
GCTTTGCCTG TTGAAGGTAC TGAGACTAGG GTTAATGCTC AGTCTGATGC CTATGAGTAT 
ATGGTTGAAT ACTCTCAGAC CAGCAAGCTG GCTGGGAGGT TGGAGAACGT TGTTGGATGG 
TATCACTCTC ACCCTGGGTA TGGATGTTGG CTCTCGGGTA TTGATGTTTC GACACAGATG 
CTTAACCAAC AGTATCAGGA GCCATTCTTA GCTGTTGTTA TTGATCCAAC AAGGACTGTT 
TCGGCTGGTA AGGTTGAGAT TGGGGCATTC AGAACATATC CAGAGGGACA TAAGATCTCG 
GATGATCATG TTTCTGAGTA TCAGACTATC CCTCTTAACA AGATTGAGGA CTTTGGTGTA 
CATTGCAAAC AGTACTACTC ATTGGACATC ACTTATTTCA AGTCATCTCT CGATAGTCAC 
CTTCTGGATC TCCTTTGGAA CAAGTACTGG GTGAACACTC TTTCTTCTTC CCCACTGTTG 
GGCAATGGAG ACTATGTTGC CGGGCAAATA TCAGACTTGG CTGAGAAGCT CGAGCAAGCG 
GAGAGTCAGC TCGCTAACTC CCGGTATGGA GGAATTGCGC CAGCCGGTCA CCAAAGGAGG 
AAAGAGGATG AGCCTCAACT CGCGAAGATA ACTCGGGATA GTGCAAAGAT AACTGTCGAG 
CAGGTCCATG GACTAATGTC ACAGGTTATC AAAGACATCT TGTTCAATTC CGCTCGTCAG 
TCCAAGAAGT CTGCTGACGA CTCATCAGAT CCAGAGCCCA TGATTACATC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSN5A ( NM_202161.1 ) cDNA ORF clone, Arabidopsis thaliana(thale cress) -> NP_973890.1 Arabidopsis thaliana COP9 signalosome 5A (CSN5A), mRNA.

Price & Availability↑

CloneID	OAb24283
Clone ID Related Accession (Same CDS sequence)	NM_202161.1
Accession Version	NM_202161.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-13
Organism	Arabidopsis thaliana(thale cress)
Product	COP9 signalosome 5A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003070).

ATGGAAGGTT CCTCGTCAGC CATCGCGAGG AAGACATGGG AGCTAGAGAA CAACATTCTC 
CCAGTGGAAC CAACCGATTC AGCCTCCGAC AGTATATTCC ACTACGACGA CGCTTCACAA 
GCCAAAATCC AGCAGGAGAA GCCATGGGCC TCCGATCCTA ACTACTTCAA GCGCGTTCAC 
ATCTCAGCCC TTGCTCTTCT CAAGATGGTG GTTCACGCTC GCTCCGGTGG CACAATCGAG 
ATCATGGGTC TTATGCAGGG TAAAACCGAG GGTGATACAA TCATCGTTAT GGATGCTTTT 
GCTTTGCCTG TTGAAGGTAC TGAGACTAGG GTTAATGCTC AGTCTGATGC CTATGAGTAT 
ATGGTTGAAT ACTCTCAGAC CAGCAAGCTG GCTGGGAGGT TGGAGAACGT TGTTGGATGG 
TATCACTCTC ACCCTGGGTA TGGATGTTGG CTCTCGGGTA TTGATGTTTC GACACAGATG 
CTTAACCAAC AGTATCAGGA GCCATTCTTA GCTGTTGTTA TTGATCCAAC AAGGACTGTT 
TCGGCTGGTA AGGTTGAGAT TGGGGCATTC AGAACATATC CAGAGGGACA TAAGATCTCG 
GATGATCATG TTTCTGAGTA TCAGACTATC CCTCTTAACA AGATTGAGGA CTTTGGTGTA 
CATTGCAAAC AGTACTACTC ATTGGACATC ACTTATTTCA AGTCATCTCT CGATAGTCAC 
CTTCTGGATC TCCTTTGGAA CAAGTACTGG GTGAACACTC TTTCTTCTTC CCCACTGTTG 
GGCAATGGAG ACTATGTTGC CGGGCAAATA TCAGACTTGG CTGAGAAGCT CGAGCAAGCG 
GAGAGTCAGC TCGCTAACTC CCGGTATGGA GGAATTGCGC CAGCCGGTCA CCAAAGGAGG 
AAAGAGGATG AGCCTCAACT CGCGAAGATA ACTCGGGATA GTGCAAAGAT AACTGTCGAG 
CAGGTCCATG GACTAATGTC ACAGGTGAGT AAATACAATC TGACAATGCT GATCCTATTT 
CCCCTTGCGG TTAATGGATC CATGAAATTG ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_973890.1
CDS	157..1212
Translation	MEGSSSAIARKTWELENNILPVEPTDSASDSIFHYDDASQAKIQQEKPWASDPNYFKRVHISALALLKMVVHARSGGTIEIMGLMQGKTEGDTIIVMDAFALPVEGTETRVNAQSDAYEYMVEYSQTSKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQMLNQQYQEPFLAVVIDPTRTVSAGKVEIGAFRTYPEGHKISDDHVSEYQTIPLNKIEDFGVHCKQYYSLDITYFKSSLDSHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQAESQLANSRYGGIAPAGHQRRKEDEPQLAKITRDSAKITVEQVHGLMSQVSKYNLTMLILFPLAVNGSMKLT

Target ORF information:

RefSeq Version	NM_202161.1
Organism	Arabidopsis thaliana(thale cress)
Definition	Arabidopsis thaliana COP9 signalosome 5A (CSN5A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_202161.1

ORF Insert Sequence:

ATGGAAGGTT CCTCGTCAGC CATCGCGAGG AAGACATGGG AGCTAGAGAA CAACATTCTC 
CCAGTGGAAC CAACCGATTC AGCCTCCGAC AGTATATTCC ACTACGACGA CGCTTCACAA 
GCCAAAATCC AGCAGGAGAA GCCATGGGCC TCCGATCCTA ACTACTTCAA GCGCGTTCAC 
ATCTCAGCCC TTGCTCTTCT CAAGATGGTG GTTCACGCTC GCTCCGGTGG CACAATCGAG 
ATCATGGGTC TTATGCAGGG TAAAACCGAG GGTGATACAA TCATCGTTAT GGATGCTTTT 
GCTTTGCCTG TTGAAGGTAC TGAGACTAGG GTTAATGCTC AGTCTGATGC CTATGAGTAT 
ATGGTTGAAT ACTCTCAGAC CAGCAAGCTG GCTGGGAGGT TGGAGAACGT TGTTGGATGG 
TATCACTCTC ACCCTGGGTA TGGATGTTGG CTCTCGGGTA TTGATGTTTC GACACAGATG 
CTTAACCAAC AGTATCAGGA GCCATTCTTA GCTGTTGTTA TTGATCCAAC AAGGACTGTT 
TCGGCTGGTA AGGTTGAGAT TGGGGCATTC AGAACATATC CAGAGGGACA TAAGATCTCG 
GATGATCATG TTTCTGAGTA TCAGACTATC CCTCTTAACA AGATTGAGGA CTTTGGTGTA 
CATTGCAAAC AGTACTACTC ATTGGACATC ACTTATTTCA AGTCATCTCT CGATAGTCAC 
CTTCTGGATC TCCTTTGGAA CAAGTACTGG GTGAACACTC TTTCTTCTTC CCCACTGTTG 
GGCAATGGAG ACTATGTTGC CGGGCAAATA TCAGACTTGG CTGAGAAGCT CGAGCAAGCG 
GAGAGTCAGC TCGCTAACTC CCGGTATGGA GGAATTGCGC CAGCCGGTCA CCAAAGGAGG 
AAAGAGGATG AGCCTCAACT CGCGAAGATA ACTCGGGATA GTGCAAAGAT AACTGTCGAG 
CAGGTCCATG GACTAATGTC ACAGGTGAGT AAATACAATC TGACAATGCT GATCCTATTT 
CCCCTTGCGG TTAATGGATC CATGAAATTG ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.
Nature408(6814)816-20(2000 Dec)
Theologis A,Ecker JR,Palm CJ,Federspiel NA,Kaul S,White O,Alonso J,Altafi H,Araujo R,Bowman CL,Brooks SY,Buehler E,Chan A,Chao Q,Chen H,Cheuk RF,Chin CW,Chung MK,Conn L,Conway AB,Conway AR,Creasy TH,Dewar K,Dunn P,Etgu P,Feldblyum TV,Feng J,Fong B,Fujii CY,Gill JE,Goldsmith AD,Haas B,Hansen NF,Hughes B,Huizar L,Hunter JL,Jenkins J,Johnson-Hopson C,Khan S,Khaykin E,Kim CJ,Koo HL,Kremenetskaia I,Kurtz DB,Kwan A,Lam B,Langin-Hooper S,Lee A,Lee JM,Lenz CA,Li JH,Li Y,Lin X,Liu SX,Liu ZA,Luros JS,Maiti R,Marziali A,Militscher J,Miranda M,Nguyen M,Nierman WC,Osborne BI,Pai G,Peterson J,Pham PK,Rizzo M,Rooney T,Rowley D,Sakano H,Salzberg SL,Schwartz JR,Shinn P,Southwick AM,Sun H,Tallon LJ,Tambunga G,Toriumi MJ,Town CD,Utterback T,Van Aken S,Vaysberg M,Vysotskaia VS,Walker M,Wu D,Yu G,Fraser CM,Venter JC,Davis RW

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CSN5A cDNA ORF clone, Arabidopsis thaliana(thale cress)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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