Gene Symbol | DYT1 |
Entrez Gene ID | 827883 |
Full Name | basic helix-loop-helix (bHLH) DNA-binding superfamily protein |
Synonyms | DYSFUNCTIONAL TAPETUM 1,T6K22.60,T6K22_60 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
ORF » Species Summary » Arabidopsis thaliana » DYT1 cDNA ORF clone
Gene Symbol | DYT1 |
Entrez Gene ID | 827883 |
Full Name | basic helix-loop-helix (bHLH) DNA-binding superfamily protein |
Synonyms | DYSFUNCTIONAL TAPETUM 1,T6K22.60,T6K22_60 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
mRNA | Protein | Name |
---|---|---|
NM_118253.1 | NP_193864.1 | basic helix-loop-helix (bHLH) DNA-binding superfamily protein |
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.
Mayer K, Sch?ller C, Wambutt R, Murphy G, Volckaert G, Pohl T, D?sterh?ft A, Stiekema W, Entian KD, Terryn N, Harris B, Ansorge W, Brandt P, Grivell L, Rieger M, Weichselgartner M, de Simone V, Obermaier B, Mache R, M?ller M, Kreis M, Delseny M, Puigdomenech P, Watson M, Schmidtheini T, Reichert B, Portatelle D, Perez-Alonso M, Boutry M, Bancroft I, Vos P, Hoheisel J, Zimmermann W, Wedler H, Ridley P, Langham SA, McCullagh B, Bilham L, Robben J, Van der Schueren J, Grymonprez B, Chuang YJ, Vandenbussche F, Braeken M, Weltjens I, Voet M, Bastiaens I, Aert R, Defoor E, Weitzenegger T, Bothe G, Ramsperger U, Hilbert H, Braun M, Holzer E, Brandt A, Peters S, van Staveren M, Dirske W, Mooijman P, Klein Lankhorst R, Rose M, Hauf J, K?tter P, Berneiser S, Hempel S, Feldpausch M, Lamberth S, Van den Daele H, De Keyser A, Buysshaert C, Gielen J, Villarroel R, De Clercq R, Van Montagu M, Rogers J, Cronin A, Quail M, Bray-Allen S, Clark L, Doggett J, Hall S, Kay M, Lennard N, McLay K, Mayes R, Pettett A, Rajandream MA, Lyne M, Benes V, Rechmann S, Borkova D, Bl?cker H, Scharfe M, Grimm M, L?hnert TH, Dose S, de Haan M, Maarse A, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, Fartmann B, Granderath K, Dauner D, Herzl A, Neumann S, Argiriou A, Vitale D, Liguori R, Piravandi E, Massenet O, Quigley F, Clabauld G, M?ndlein A, Felber R, Schnabl S, Hiller R, Schmidt W, Lecharny A, Aubourg S, Chefdor F, Cooke R, Berger C, Montfort A, Casacuberta E, Gibbons T, Weber N, Vandenbol M, Bargues M, Terol J, Torres A, Perez-Perez A, Purnelle B, Bent E, Johnson S, Tacon D, Jesse T, Heijnen L, Schwarz S, Scholler P, Heber S, Francs P, Bielke C, Frishman D, Haase D, Lemcke K, Mewes HW, Stocker S, Zaccaria P, Bevan M, Wilson RK, de la Bastide M, Habermann K, Parnell L, Dedhia N, Gnoj L, Schutz K, Huang E, Spiegel L, Sehkon M, Murray J, Sheet P, Cordes M, Abu-Threideh J, Stoneking T, Kalicki J, Graves T, Harmon G, Edwards J, Latreille P, Courtney L, Cloud J, Abbott A, Scott K, Johnson D, Minx P, Bentley D, Fulton B, Miller N, Greco T, Kemp K, Kramer J, Fulton L, Mardis E, Dante M, Pepin K, Hillier L, Nelson J, Spieth J, Ryan E, Andrews S, Geisel C, Layman D, Du H, Ali J, Berghoff A, Jones K, Drone K, Cotton M, Joshu C, Antonoiu B, Zidanic M, Strong C, Sun H, Lamar B, Yordan C, Ma P, Zhong J, Preston R, Vil D, Shekher M, Matero A, Shah R, Swaby IK, O'Shaughnessy A, Rodriguez M, Hoffmann J, Till S, Granat S, Shohdy N, Hasegawa A, Hameed A, Lodhi M, Johnson A, Chen E, Marra M, Martienssen R, McCombie WR
Nature402(6763)769-77(1999 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The results of this study suggested that motor impairments in DYT1 KI animals only exhibit when the sensory stimuli are strongly altered during performance.
Title: Sensorimotor tests unmask a phenotype in the DYT1 knock-in mouse model of dystonia.
DYT1 dystonia is a network disorder, with crucial nodes in sensory-motor integration of posterior parietal structures.
Title: Functional Connectivity Networks in Asymptomatic and Symptomatic DYT1 Carriers.
we show the behavioral and molecular consequences of stressing the endoplasmic reticulum in DYT1 mice by increasing the amount of misfolded proteins
Title: Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.
Here the authors demonstrate abnormal risk taking in DYT1 dystonia patients, which is correlated with disease severity, thereby supporting striatal plasticity in shaping choice behavior in humans.
Title: DYT1 dystonia increases risk taking in humans.
Data said that the normal spatio-temporal subcellular localization of DYT1 is important for DYT1 function and/or that the BIF domains from different bHLH members might be functionally distinct.
Title: Feedback Regulation of DYT1 by Interactions with Downstream bHLH Factors Promotes DYT1 Nuclear Localization and Anther Development.
The following DYT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DYT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OAb15555 | |
Clone ID Related Accession (Same CDS sequence) | NM_118253.1 | |
Accession Version | NM_118253.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-13 | |
Organism | Arabidopsis thaliana(thale cress) | |
Product | basic helix-loop-helix (bHLH) DNA-binding superfamily protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003075). COMPLETENESS: incomplete on both ends. |
1 | ATGGGTGGAG GAAGCAGATT TCAAGAACCA GTGAGGATGA GCCGTAGGAA ACAAGTAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_193864.1 |
CDS | 1..624 |
Translation |
Target ORF information:
Target ORF information:
|
NM_118253.1 |
1 | ATGGGTGGAG GAAGCAGATT TCAAGAACCA GTGAGGATGA GCCGTAGGAA ACAAGTAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. |