LOC107998473 cDNA ORF clone, Apis cerana(Asiatic honeybee)

Gene
Clones
gRNAs

Summary

Gene Symbol	LOC107998473
Entrez Gene ID	107998473
Full Name	esterase E4-like
Gene Type	protein-coding
Organism	Apis cerana(Asiatic honeybee)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017057775.2	XP_016913264.1	esterase E4
XM_017057775.1	XP_016913264.1	esterase E4-like

Pathways from BioSystems
Gene Ontology

The following LOC107998473 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LOC107998473 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OAp37804	XM_017057775.2 Latest version!	Apis cerana esterase E4 (LOC107998473), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
View Old Accession Versions >>
OAp37804	XM_017057775.1	Apis cerana esterase E4-like (LOC107998473), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LOC107998473 ( XM_017057775.2 ) cDNA ORF clone, Apis cerana(Asiatic honeybee) -> XP_016913264.1 Apis cerana esterase E4 (LOC107998473), mRNA.

Price & Availability↑

CloneID	OAp37804
Clone ID Related Accession (Same CDS sequence)	XM_017057775.2 , XM_017057775.1
Accession Version	XM_017057775.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-16
Organism	Apis cerana(Asiatic honeybee)
Product	esterase E4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_016019242.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 17, 2019 this sequence version replaced XM_017057775.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Apis cerana Annotation Release 101 Annotation Version :: 101 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAATATA ATATTTTGAT TTTTTGTATC GTTGGCGCTG CTCTCTGTGA ATGTTCAATC 
GAGCAACCAT TGGTCGAAGC CCCGATTGGG AAAATTCGCG GTTCAATTAT CGTCTCAAGG 
CATGGGAGGA AGATTTATTC GTTCCGTGGA GTGAGATATG GGGAGCCACC TGTCGGAAAG 
CAACGTTTTC AACCTCCAAT CCCAGCGGCG GATTGGCAAA ACGTGTTCGA CGCCACCGAG 
GAAGGACCTA GTTGCCCTCA TCCCGATGGC GTGTTGCAAG CGGAGGATTG TCTACGTTTG 
AACGTGTACA CCACTAAACT ACCGTGCGAG GAGAAAAATG TAAAGAGACC AGTTATGATA 
TTCATACATC CCGGCGGTTT TACCAGTTTC TCCGGGCAAA GTTCAATTTT CGGCCCTCAA 
TACCTACTCG ACAAAGATAT CGTATTGGTC ACGATTAACT ATCGTCTCGG GGCTCTAGGT 
TTCTTGAATA CAGGCGACAG TGAGGCACCC GGCAACATGG GCTTGAAGGA TCAGGTAGAG 
GCGTTTAGAT GGGTTCGAAG GAACATAGCC GCGTTCGGCG GCGATCCGAG TTCCGTCACG 
TTGTGCGGTT ACAGCGCGGG CAGTTTCAGC ATAATGTTGC ACATGGTCTC CCCGATGTCT 
AAAGATCTGT TCCACAGAGC TATATCGATG AGCGGCTCGG CCATCAAGCC GGAAGTCTAC 
ACAGGTGTCG CGGAACACGG GCAGAAGGAA CTGGTTCAAA GGCAGGCACG GCTGTTGAAT 
TGTCCCACCG ATTCGACCGC TTCCATGTTG AACTGTTTGA TCGAGAAACC CGTGGAAAAC 
TTCACGAACA CGTTGGCCAA CTTGACGGAT TGGTATGGAA ATCCTATTCT TCTTTGGACA 
CCAGCCGTGG AGCCCCAAGT CCCTGGTGTC GAACGATTCT TGTCCGAACA ACCGTACGAC 
TCGATCACGC AAGGGAAATT CCACCAAGTT CCTTACATAC TCGGGGTCAC GGAACACGAG 
TTTGCCGGCG TTGCCGCGTT GTACGAGAGG AACGACAAGG TGGACAACGG GAGTTTGTAT 
CGAGAGGTGA ACAACAATTG GAACATGGTC GCCCCGATCT TTTGCATGTA CGAACGCGAT 
ACTTCGCGAT CGAATTACAT AAGCAGGCAA TTGAGACAGT TTTATTTCAA AAACGAGGCG 
ATCAGCGAAA CGACTCTCCT CCAACTTGGC AAAGTATACG GCGATTGTAT AACCATATTC 
CCCATGTATC GAGCGGTTAA ATTGTTCGCT TCGAACTCGA GAGAGCCGGT ATACTTTTAC 
AAATTTACGT ACGAGGGACG ATTCGGTTTC TACAGATGGA GCAACGATAC GGCATACAAT 
CCGTCGCATC ACGACGATTT GCAGTATCTG TTTCACGCGA AACAATTCCC GTTTCTCCCT 
TATTTGGAGG ATGACGCACC GGAAGCGCCC ATGGTTGAGC TTTACACGAG CATGTGGTCC 
AATTTCATAA TAAACGGGGA ACCGATCCCG AGGAACGATG ACAGATTCAG AAACGTTTCG 
TGGGAGACGT TCGACCCCTC GAAAACGAAT TATCTGGAGA TCGATCTTCG TTTGGGAATG 
AAAACTGAAT TCTTCCCCGA AAGGATGCGC TTATGGGAAA AATTATTCCC GTTGCCCTCT 
CAAGCTTCGA GAGGAGTGAA GCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016913264.1
CDS	141..1847
Translation	MKYNILIFCIVGAALCECSIEQPLVEAPIGKIRGSIIVSRHGRKIYSFRGVRYGEPPVGKQRFQPPIPAADWQNVFDATEEGPSCPHPDGVLQAEDCLRLNVYTTKLPCEEKNVKRPVMIFIHPGGFTSFSGQSSIFGPQYLLDKDIVLVTINYRLGALGFLNTGDSEAPGNMGLKDQVEAFRWVRRNIAAFGGDPSSVTLCGYSAGSFSIMLHMVSPMSKDLFHRAISMSGSAIKPEVYTGVAEHGQKELVQRQARLLNCPTDSTASMLNCLIEKPVENFTNTLANLTDWYGNPILLWTPAVEPQVPGVERFLSEQPYDSITQGKFHQVPYILGVTEHEFAGVAALYERNDKVDNGSLYREVNNNWNMVAPIFCMYERDTSRSNYISRQLRQFYFKNEAISETTLLQLGKVYGDCITIFPMYRAVKLFASNSREPVYFYKFTYEGRFGFYRWSNDTAYNPSHHDDLQYLFHAKQFPFLPYLEDDAPEAPMVELYTSMWSNFIINGEPIPRNDDRFRNVSWETFDPSKTNYLEIDLRLGMKTEFFPERMRLWEKLFPLPSQASRGVKH

Target ORF information:

RefSeq Version	XM_017057775.2
Organism	Apis cerana(Asiatic honeybee)
Definition	Apis cerana esterase E4 (LOC107998473), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017057775.2

ORF Insert Sequence:

ATGAAATATA ATATTTTGAT TTTTTGTATC GTTGGCGCTG CTCTCTGTGA ATGTTCAATC 
GAGCAACCAT TGGTCGAAGC CCCGATTGGG AAAATTCGCG GTTCAATTAT CGTCTCAAGG 
CATGGGAGGA AGATTTATTC GTTCCGTGGA GTGAGATATG GGGAGCCACC TGTCGGAAAG 
CAACGTTTTC AACCTCCAAT CCCAGCGGCG GATTGGCAAA ACGTGTTCGA CGCCACCGAG 
GAAGGACCTA GTTGCCCTCA TCCCGATGGC GTGTTGCAAG CGGAGGATTG TCTACGTTTG 
AACGTGTACA CCACTAAACT ACCGTGCGAG GAGAAAAATG TAAAGAGACC AGTTATGATA 
TTCATACATC CCGGCGGTTT TACCAGTTTC TCCGGGCAAA GTTCAATTTT CGGCCCTCAA 
TACCTACTCG ACAAAGATAT CGTATTGGTC ACGATTAACT ATCGTCTCGG GGCTCTAGGT 
TTCTTGAATA CAGGCGACAG TGAGGCACCC GGCAACATGG GCTTGAAGGA TCAGGTAGAG 
GCGTTTAGAT GGGTTCGAAG GAACATAGCC GCGTTCGGCG GCGATCCGAG TTCCGTCACG 
TTGTGCGGTT ACAGCGCGGG CAGTTTCAGC ATAATGTTGC ACATGGTCTC CCCGATGTCT 
AAAGATCTGT TCCACAGAGC TATATCGATG AGCGGCTCGG CCATCAAGCC GGAAGTCTAC 
ACAGGTGTCG CGGAACACGG GCAGAAGGAA CTGGTTCAAA GGCAGGCACG GCTGTTGAAT 
TGTCCCACCG ATTCGACCGC TTCCATGTTG AACTGTTTGA TCGAGAAACC CGTGGAAAAC 
TTCACGAACA CGTTGGCCAA CTTGACGGAT TGGTATGGAA ATCCTATTCT TCTTTGGACA 
CCAGCCGTGG AGCCCCAAGT CCCTGGTGTC GAACGATTCT TGTCCGAACA ACCGTACGAC 
TCGATCACGC AAGGGAAATT CCACCAAGTT CCTTACATAC TCGGGGTCAC GGAACACGAG 
TTTGCCGGCG TTGCCGCGTT GTACGAGAGG AACGACAAGG TGGACAACGG GAGTTTGTAT 
CGAGAGGTGA ACAACAATTG GAACATGGTC GCCCCGATCT TTTGCATGTA CGAACGCGAT 
ACTTCGCGAT CGAATTACAT AAGCAGGCAA TTGAGACAGT TTTATTTCAA AAACGAGGCG 
ATCAGCGAAA CGACTCTCCT CCAACTTGGC AAAGTATACG GCGATTGTAT AACCATATTC 
CCCATGTATC GAGCGGTTAA ATTGTTCGCT TCGAACTCGA GAGAGCCGGT ATACTTTTAC 
AAATTTACGT ACGAGGGACG ATTCGGTTTC TACAGATGGA GCAACGATAC GGCATACAAT 
CCGTCGCATC ACGACGATTT GCAGTATCTG TTTCACGCGA AACAATTCCC GTTTCTCCCT 
TATTTGGAGG ATGACGCACC GGAAGCGCCC ATGGTTGAGC TTTACACGAG CATGTGGTCC 
AATTTCATAA TAAACGGGGA ACCGATCCCG AGGAACGATG ACAGATTCAG AAACGTTTCG 
TGGGAGACGT TCGACCCCTC GAAAACGAAT TATCTGGAGA TCGATCTTCG TTTGGGAATG 
AAAACTGAAT TCTTCCCCGA AAGGATGCGC TTATGGGAAA AATTATTCCC GTTGCCCTCT 
CAAGCTTCGA GAGGAGTGAA GCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LOC107998473 ( XM_017057775.1 ) cDNA ORF clone, Apis cerana(Asiatic honeybee) -> XP_016913264.1 Apis cerana esterase E4-like (LOC107998473), mRNA.

Price & Availability↑

CloneID	OAp37804
Clone ID Related Accession (Same CDS sequence)	XM_017057775.2 , XM_017057775.1
Accession Version	XM_017057775.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-08
Organism	Apis cerana(Asiatic honeybee)
Product	esterase E4-like
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_016019242.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Apis cerana Annotation Release 100 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAATATA ATATTTTGAT TTTTTGTATC GTTGGCGCTG CTCTCTGTGA ATGTTCAATC 
GAGCAACCAT TGGTCGAAGC CCCGATTGGG AAAATTCGCG GTTCAATTAT CGTCTCAAGG 
CATGGGAGGA AGATTTATTC GTTCCGTGGA GTGAGATATG GGGAGCCACC TGTCGGAAAG 
CAACGTTTTC AACCTCCAAT CCCAGCGGCG GATTGGCAAA ACGTGTTCGA CGCCACCGAG 
GAAGGACCTA GTTGCCCTCA TCCCGATGGC GTGTTGCAAG CGGAGGATTG TCTACGTTTG 
AACGTGTACA CCACTAAACT ACCGTGCGAG GAGAAAAATG TAAAGAGACC AGTTATGATA 
TTCATACATC CCGGCGGTTT TACCAGTTTC TCCGGGCAAA GTTCAATTTT CGGCCCTCAA 
TACCTACTCG ACAAAGATAT CGTATTGGTC ACGATTAACT ATCGTCTCGG GGCTCTAGGT 
TTCTTGAATA CAGGCGACAG TGAGGCACCC GGCAACATGG GCTTGAAGGA TCAGGTAGAG 
GCGTTTAGAT GGGTTCGAAG GAACATAGCC GCGTTCGGCG GCGATCCGAG TTCCGTCACG 
TTGTGCGGTT ACAGCGCGGG CAGTTTCAGC ATAATGTTGC ACATGGTCTC CCCGATGTCT 
AAAGATCTGT TCCACAGAGC TATATCGATG AGCGGCTCGG CCATCAAGCC GGAAGTCTAC 
ACAGGTGTCG CGGAACACGG GCAGAAGGAA CTGGTTCAAA GGCAGGCACG GCTGTTGAAT 
TGTCCCACCG ATTCGACCGC TTCCATGTTG AACTGTTTGA TCGAGAAACC CGTGGAAAAC 
TTCACGAACA CGTTGGCCAA CTTGACGGAT TGGTATGGAA ATCCTATTCT TCTTTGGACA 
CCAGCCGTGG AGCCCCAAGT CCCTGGTGTC GAACGATTCT TGTCCGAACA ACCGTACGAC 
TCGATCACGC AAGGGAAATT CCACCAAGTT CCTTACATAC TCGGGGTCAC GGAACACGAG 
TTTGCCGGCG TTGCCGCGTT GTACGAGAGG AACGACAAGG TGGACAACGG GAGTTTGTAT 
CGAGAGGTGA ACAACAATTG GAACATGGTC GCCCCGATCT TTTGCATGTA CGAACGCGAT 
ACTTCGCGAT CGAATTACAT AAGCAGGCAA TTGAGACAGT TTTATTTCAA AAACGAGGCG 
ATCAGCGAAA CGACTCTCCT CCAACTTGGC AAAGTATACG GCGATTGTAT AACCATATTC 
CCCATGTATC GAGCGGTTAA ATTGTTCGCT TCGAACTCGA GAGAGCCGGT ATACTTTTAC 
AAATTTACGT ACGAGGGACG ATTCGGTTTC TACAGATGGA GCAACGATAC GGCATACAAT 
CCGTCGCATC ACGACGATTT GCAGTATCTG TTTCACGCGA AACAATTCCC GTTTCTCCCT 
TATTTGGAGG ATGACGCACC GGAAGCGCCC ATGGTTGAGC TTTACACGAG CATGTGGTCC 
AATTTCATAA TAAACGGGGA ACCGATCCCG AGGAACGATG ACAGATTCAG AAACGTTTCG 
TGGGAGACGT TCGACCCCTC GAAAACGAAT TATCTGGAGA TCGATCTTCG TTTGGGAATG 
AAAACTGAAT TCTTCCCCGA AAGGATGCGC TTATGGGAAA AATTATTCCC GTTGCCCTCT 
CAAGCTTCGA GAGGAGTGAA GCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016913264.1
CDS	141..1847
Translation	MKYNILIFCIVGAALCECSIEQPLVEAPIGKIRGSIIVSRHGRKIYSFRGVRYGEPPVGKQRFQPPIPAADWQNVFDATEEGPSCPHPDGVLQAEDCLRLNVYTTKLPCEEKNVKRPVMIFIHPGGFTSFSGQSSIFGPQYLLDKDIVLVTINYRLGALGFLNTGDSEAPGNMGLKDQVEAFRWVRRNIAAFGGDPSSVTLCGYSAGSFSIMLHMVSPMSKDLFHRAISMSGSAIKPEVYTGVAEHGQKELVQRQARLLNCPTDSTASMLNCLIEKPVENFTNTLANLTDWYGNPILLWTPAVEPQVPGVERFLSEQPYDSITQGKFHQVPYILGVTEHEFAGVAALYERNDKVDNGSLYREVNNNWNMVAPIFCMYERDTSRSNYISRQLRQFYFKNEAISETTLLQLGKVYGDCITIFPMYRAVKLFASNSREPVYFYKFTYEGRFGFYRWSNDTAYNPSHHDDLQYLFHAKQFPFLPYLEDDAPEAPMVELYTSMWSNFIINGEPIPRNDDRFRNVSWETFDPSKTNYLEIDLRLGMKTEFFPERMRLWEKLFPLPSQASRGVKH

Target ORF information:

RefSeq Version	XM_017057775.1
Organism	Apis cerana(Asiatic honeybee)
Definition	Apis cerana esterase E4-like (LOC107998473), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017057775.1

ORF Insert Sequence:

ATGAAATATA ATATTTTGAT TTTTTGTATC GTTGGCGCTG CTCTCTGTGA ATGTTCAATC 
GAGCAACCAT TGGTCGAAGC CCCGATTGGG AAAATTCGCG GTTCAATTAT CGTCTCAAGG 
CATGGGAGGA AGATTTATTC GTTCCGTGGA GTGAGATATG GGGAGCCACC TGTCGGAAAG 
CAACGTTTTC AACCTCCAAT CCCAGCGGCG GATTGGCAAA ACGTGTTCGA CGCCACCGAG 
GAAGGACCTA GTTGCCCTCA TCCCGATGGC GTGTTGCAAG CGGAGGATTG TCTACGTTTG 
AACGTGTACA CCACTAAACT ACCGTGCGAG GAGAAAAATG TAAAGAGACC AGTTATGATA 
TTCATACATC CCGGCGGTTT TACCAGTTTC TCCGGGCAAA GTTCAATTTT CGGCCCTCAA 
TACCTACTCG ACAAAGATAT CGTATTGGTC ACGATTAACT ATCGTCTCGG GGCTCTAGGT 
TTCTTGAATA CAGGCGACAG TGAGGCACCC GGCAACATGG GCTTGAAGGA TCAGGTAGAG 
GCGTTTAGAT GGGTTCGAAG GAACATAGCC GCGTTCGGCG GCGATCCGAG TTCCGTCACG 
TTGTGCGGTT ACAGCGCGGG CAGTTTCAGC ATAATGTTGC ACATGGTCTC CCCGATGTCT 
AAAGATCTGT TCCACAGAGC TATATCGATG AGCGGCTCGG CCATCAAGCC GGAAGTCTAC 
ACAGGTGTCG CGGAACACGG GCAGAAGGAA CTGGTTCAAA GGCAGGCACG GCTGTTGAAT 
TGTCCCACCG ATTCGACCGC TTCCATGTTG AACTGTTTGA TCGAGAAACC CGTGGAAAAC 
TTCACGAACA CGTTGGCCAA CTTGACGGAT TGGTATGGAA ATCCTATTCT TCTTTGGACA 
CCAGCCGTGG AGCCCCAAGT CCCTGGTGTC GAACGATTCT TGTCCGAACA ACCGTACGAC 
TCGATCACGC AAGGGAAATT CCACCAAGTT CCTTACATAC TCGGGGTCAC GGAACACGAG 
TTTGCCGGCG TTGCCGCGTT GTACGAGAGG AACGACAAGG TGGACAACGG GAGTTTGTAT 
CGAGAGGTGA ACAACAATTG GAACATGGTC GCCCCGATCT TTTGCATGTA CGAACGCGAT 
ACTTCGCGAT CGAATTACAT AAGCAGGCAA TTGAGACAGT TTTATTTCAA AAACGAGGCG 
ATCAGCGAAA CGACTCTCCT CCAACTTGGC AAAGTATACG GCGATTGTAT AACCATATTC 
CCCATGTATC GAGCGGTTAA ATTGTTCGCT TCGAACTCGA GAGAGCCGGT ATACTTTTAC 
AAATTTACGT ACGAGGGACG ATTCGGTTTC TACAGATGGA GCAACGATAC GGCATACAAT 
CCGTCGCATC ACGACGATTT GCAGTATCTG TTTCACGCGA AACAATTCCC GTTTCTCCCT 
TATTTGGAGG ATGACGCACC GGAAGCGCCC ATGGTTGAGC TTTACACGAG CATGTGGTCC 
AATTTCATAA TAAACGGGGA ACCGATCCCG AGGAACGATG ACAGATTCAG AAACGTTTCG 
TGGGAGACGT TCGACCCCTC GAAAACGAAT TATCTGGAGA TCGATCTTCG TTTGGGAATG 
AAAACTGAAT TCTTCCCCGA AAGGATGCGC TTATGGGAAA AATTATTCCC GTTGCCCTCT 
CAAGCTTCGA GAGGAGTGAA GCATTGA