AgaP_AGAP004159 cDNA ORF clone, Anopheles gambiae str. PEST

The following AgaP_AGAP004159 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AgaP_AGAP004159 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OAh03429 XM_003436683.1
Latest version!
Anopheles gambiae str. PEST AGAP004159-RB (AgaP_AGAP004159), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $342.30
$489.00
OAh03430 XM_313043.5
Latest version!
Anopheles gambiae str. PEST AGAP004159-RA (AgaP_AGAP004159), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $342.30
$489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OAh03429
    Clone ID Related Accession (Same CDS sequence) XM_003436683.1
    Accession Version XM_003436683.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1890bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-04-25
    Organism Anopheles gambiae str. PEST
    Product AGAP004159-PB
    Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NT_078266).

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGCAGGCTC GAAGCGTTAT CCTGAACGCG AAACAGACGG TGGACGCGCT GCGGACGCTG 
    GTCGGGACCG CCTCGCCGAA GAAGTCGCTC ACCAAGGCGG CCACATCGGC GGCGGTGCAG
    GCGTTCCAGG CGCGCGACTA CCATGAGGTG ACGGGCGACA TCATCGTACC GTCGATGGTG
    CAGGGCATCG ACCATCTGCG CGATCCGCGC CTCAACAAGG GGCTGGCGTT CACGCTGGAG
    GAGCGCCAAA TCCTCGGCAT CCACGGGCTG CAGCCGGCCC GCTTCAAGTC GCAGGAGGAG
    CAGCTGGAGC TGTGCCGCAT CTCGATCTCG CGCTACCAGG AAGACCTCAA CAAGTACCTG
    TACCTGGTCG ATTTGCAGGA CCGCAACGAG CGGCTGTTCT TCCGACTGAT CTCGGAGGAC
    GTGGAAAAGA TGATGCCGAT CGTCTACACG CCCACCGTCG GGCTGGCCTG CCAAAAGTTC
    GGCCTGATCT ATCGGCGACC GCGCGGCCTG TTCGTGACGA TTAACGACCG GGGTCACGTG
    TTCGACGTGC TGCGCAACTG GCCGGAACCG GACGTGCGCG CGATCGTCGT GACGGACGGC
    GAGCGCATCC TGGGCCTGGG CGATCTTGGC GCGTGCGGCA TGGGAATCCC GGTCGGCAAG
    CTGGCGCTGT ACACCGCGCT CGCCGGTATC CCGCCGCACC AGTGTCTGCC GATCGTGATC
    GACGTCGGCA CGAACAACAA GGACCTGCTG GAGGATCCGC TGTACATTGG GCTGCGGCAC
    CAGCGCGTGC AGGGCAAGGA GTACGACGAG TTTATCGACG AGTTCATGCA GGCGGTCGTG
    AAGCGGTACG GCCAGAACAC GCTCATCCAG TTCGAGGACT TTGGCAACCA CAACGCGTTC
    CGCTTTCTGG ACAAGTACCG CAACACCTAC TGCACGTTCA ACGACGACAT CCAGGGCACG
    GCCTCGGTCG CGGTCGCGGG GATGCTGGCC GCGAAGCGCA TCACCAACAA GCGCATCTCG
    GACAACACGT TCCTGTTTCT GGGTGCGGGC GAGGCGGCCG TCGGCATTGC CGATCTGGTG
    GTGAAAGCGA TGCAGGCGGA GGGCACGGGC CTGCAGGAGG CACGCGACAA GATCTGGATG
    TTCGACATCG ACGGTCTGCT GGCGAAGGGC CGCCCGGAGG GTCGGCTAGG CGGGCACAAA
    GCGTACTATG CCAAAGATCA CGGCGTGATG AAGAACTTTG CCGACGTGGT GAAGGAGGTG
    AAACCGTCGG TGCTGATCGG TGCGTCCGCG GCGGGCGGCG CGTTTACGCC GGAGATTCTG
    CAGGCCATGG GCCAGTTCAA CGAGCGGCCG ATCATTTTCG CCTTGTCCAA CCCGACCTCC
    AAGGCGGAGT GTACGGCACA GGCGGCCTAT GATAATACCG AGGTACGTTT GGGTCGGTGC
    ATTTTTGCGT CGGGGTCTCC GTTCCCGCCG GTGCAGTATG GCGGAAAGAC GTTCATCACC
    GGCCAGGGCA ACAACGCGTA CATCTTCCCG GGCGTCGCTT TGGGTGTCAT CGTTACCGGC
    ACGCACCACA TCCCGGAGGA CATGTTCCTT ATCGCTGCCC AGGTCGTCGC GGACCACGTA
    TCCGAGGCGG ACCTCGAGAA GGGTTCGCTC TACCCTCCGC TAAGTGCCAT TAAGGAGTGT
    TCGATGGATA TCGCAGTCGG CGTTACGAAC TACGCATATC AGAAGGGTCT CGCCTCGACC
    TACCCCGAGC CGGAGGACAA GAAGTCGTAC ATTGAGTCGC ACCTGTACAA CTACAACTAC
    CAGAGCGCCA TGCCCGTCAC CTGGCCATGG CCGAAGCAGC ACGAATCATC GAAAACGCGG
    GAAATCAATC CGACCAAACT GCAGGCATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_003436731.1
    CDS399..2288
    Translation

    Target ORF information:

    RefSeq Version XM_003436683.1
    Organism Anopheles gambiae str. PEST
    Definition Anopheles gambiae str. PEST AGAP004159-RB (AgaP_AGAP004159), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_003436683.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGCAGGCTC GAAGCGTTAT CCTGAACGCG AAACAGACGG TGGACGCGCT GCGGACGCTG 
    GTCGGGACCG CCTCGCCGAA GAAGTCGCTC ACCAAGGCGG CCACATCGGC GGCGGTGCAG
    GCGTTCCAGG CGCGCGACTA CCATGAGGTG ACGGGCGACA TCATCGTACC GTCGATGGTG
    CAGGGCATCG ACCATCTGCG CGATCCGCGC CTCAACAAGG GGCTGGCGTT CACGCTGGAG
    GAGCGCCAAA TCCTCGGCAT CCACGGGCTG CAGCCGGCCC GCTTCAAGTC GCAGGAGGAG
    CAGCTGGAGC TGTGCCGCAT CTCGATCTCG CGCTACCAGG AAGACCTCAA CAAGTACCTG
    TACCTGGTCG ATTTGCAGGA CCGCAACGAG CGGCTGTTCT TCCGACTGAT CTCGGAGGAC
    GTGGAAAAGA TGATGCCGAT CGTCTACACG CCCACCGTCG GGCTGGCCTG CCAAAAGTTC
    GGCCTGATCT ATCGGCGACC GCGCGGCCTG TTCGTGACGA TTAACGACCG GGGTCACGTG
    TTCGACGTGC TGCGCAACTG GCCGGAACCG GACGTGCGCG CGATCGTCGT GACGGACGGC
    GAGCGCATCC TGGGCCTGGG CGATCTTGGC GCGTGCGGCA TGGGAATCCC GGTCGGCAAG
    CTGGCGCTGT ACACCGCGCT CGCCGGTATC CCGCCGCACC AGTGTCTGCC GATCGTGATC
    GACGTCGGCA CGAACAACAA GGACCTGCTG GAGGATCCGC TGTACATTGG GCTGCGGCAC
    CAGCGCGTGC AGGGCAAGGA GTACGACGAG TTTATCGACG AGTTCATGCA GGCGGTCGTG
    AAGCGGTACG GCCAGAACAC GCTCATCCAG TTCGAGGACT TTGGCAACCA CAACGCGTTC
    CGCTTTCTGG ACAAGTACCG CAACACCTAC TGCACGTTCA ACGACGACAT CCAGGGCACG
    GCCTCGGTCG CGGTCGCGGG GATGCTGGCC GCGAAGCGCA TCACCAACAA GCGCATCTCG
    GACAACACGT TCCTGTTTCT GGGTGCGGGC GAGGCGGCCG TCGGCATTGC CGATCTGGTG
    GTGAAAGCGA TGCAGGCGGA GGGCACGGGC CTGCAGGAGG CACGCGACAA GATCTGGATG
    TTCGACATCG ACGGTCTGCT GGCGAAGGGC CGCCCGGAGG GTCGGCTAGG CGGGCACAAA
    GCGTACTATG CCAAAGATCA CGGCGTGATG AAGAACTTTG CCGACGTGGT GAAGGAGGTG
    AAACCGTCGG TGCTGATCGG TGCGTCCGCG GCGGGCGGCG CGTTTACGCC GGAGATTCTG
    CAGGCCATGG GCCAGTTCAA CGAGCGGCCG ATCATTTTCG CCTTGTCCAA CCCGACCTCC
    AAGGCGGAGT GTACGGCACA GGCGGCCTAT GATAATACCG AGGTACGTTT GGGTCGGTGC
    ATTTTTGCGT CGGGGTCTCC GTTCCCGCCG GTGCAGTATG GCGGAAAGAC GTTCATCACC
    GGCCAGGGCA ACAACGCGTA CATCTTCCCG GGCGTCGCTT TGGGTGTCAT CGTTACCGGC
    ACGCACCACA TCCCGGAGGA CATGTTCCTT ATCGCTGCCC AGGTCGTCGC GGACCACGTA
    TCCGAGGCGG ACCTCGAGAA GGGTTCGCTC TACCCTCCGC TAAGTGCCAT TAAGGAGTGT
    TCGATGGATA TCGCAGTCGG CGTTACGAAC TACGCATATC AGAAGGGTCT CGCCTCGACC
    TACCCCGAGC CGGAGGACAA GAAGTCGTAC ATTGAGTCGC ACCTGTACAA CTACAACTAC
    CAGAGCGCCA TGCCCGTCAC CTGGCCATGG CCGAAGCAGC ACGAATCATC GAAAACGCGG
    GAAATCAATC CGACCAAACT GCAGGCATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OAh03430
    Clone ID Related Accession (Same CDS sequence) XM_313043.5
    Accession Version XM_313043.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1716bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-04-25
    Organism Anopheles gambiae str. PEST
    Product AGAP004159-PA
    Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NT_078266). On Sep 28, 2011 this sequence version replaced XM_313043.4.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGGTGCAGG GCATCGACCA TCTGCGCGAT CCGCGCCTCA ACAAGGGGCT GGCGTTCACG 
    CTGGAGGAGC GCCAAATCCT CGGCATCCAC GGGCTGCAGC CGGCCCGCTT CAAGTCGCAG
    GAGGAGCAGC TGGAGCTGTG CCGCATCTCG ATCTCGCGCT ACCAGGAAGA CCTCAACAAG
    TACCTGTACC TGGTCGATTT GCAGGACCGC AACGAGCGGC TGTTCTTCCG ACTGATCTCG
    GAGGACGTGG AAAAGATGAT GCCGATCGTC TACACGCCCA CCGTCGGGCT GGCCTGCCAA
    AAGTTCGGCC TGATCTATCG GCGACCGCGC GGCCTGTTCG TGACGATTAA CGACCGGGGT
    CACGTGTTCG ACGTGCTGCG CAACTGGCCG GAACCGGACG TGCGCGCGAT CGTCGTGACG
    GACGGCGAGC GCATCCTGGG CCTGGGCGAT CTTGGCGCGT GCGGCATGGG AATCCCGGTC
    GGCAAGCTGG CGCTGTACAC CGCGCTCGCC GGTATCCCGC CGCACCAGTG TCTGCCGATC
    GTGATCGACG TCGGCACGAA CAACAAGGAC CTGCTGGAGG ATCCGCTGTA CATTGGGCTG
    CGGCACCAGC GCGTGCAGGG CAAGGAGTAC GACGAGTTTA TCGACGAGTT CATGCAGGCG
    GTCGTGAAGC GGTACGGCCA GAACACGCTC ATCCAGTTCG AGGACTTTGG CAACCACAAC
    GCGTTCCGCT TTCTGGACAA GTACCGCAAC ACCTACTGCA CGTTCAACGA CGACATCCAG
    GGCACGGCCT CGGTCGCGGT CGCGGGGATG CTGGCCGCGA AGCGCATCAC CAACAAGCGC
    ATCTCGGACA ACACGTTCCT GTTTCTGGGT GCGGGCGAGG CGGCCGTCGG CATTGCCGAT
    CTGGTGGTGA AAGCGATGCA GGCGGAGGGC ACGGGCCTGC AGGAGGCACG CGACAAGATC
    TGGATGTTCG ACATCGACGG TCTGCTGGCG AAGGGCCGCC CGGAGGGTCG GCTAGGCGGG
    CACAAAGCGT ACTATGCCAA AGATCACGGC GTGATGAAGA ACTTTGCCGA CGTGGTGAAG
    GAGGTGAAAC CGTCGGTGCT GATCGGTGCG TCCGCGGCGG GCGGCGCGTT TACGCCGGAG
    ATTCTGCAGG CCATGGGCCA GTTCAACGAG CGGCCGATCA TTTTCGCCTT GTCCAACCCG
    ACCTCCAAGG CGGAGTGTAC GGCACAGGCG GCCTATGATA ATACCGAGGT ACGTTTGGGT
    CGGTGCATTT TTGCGTCGGG GTCTCCGTTC CCGCCGGTGC AGTATGGCGG AAAGACGTTC
    ATCACCGGCC AGGGCAACAA CGCGTACATC TTCCCGGGCG TCGCTTTGGG TGTCATCGTT
    ACCGGCACGC ACCACATCCC GGAGGACATG TTCCTTATCG CTGCCCAGGT CGTCGCGGAC
    CACGTATCCG AGGCGGACCT CGAGAAGGGT TCGCTCTACC CTCCGCTAAG TGCCATTAAG
    GAGTGTTCGA TGGATATCGC AGTCGGCGTT ACGAACTACG CATATCAGAA GGGTCTCGCC
    TCGACCTACC CCGAGCCGGA GGACAAGAAG TCGTACATTG AGTCGCACCT GTACAACTAC
    AACTACCAGA GCGCCATGCC CGTCACCTGG CCATGGCCGA AGCAGCACGA ATCATCGAAA
    ACGCGGGAAA TCAATCCGAC CAAACTGCAG GCATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_313043.5
    CDS274..1989
    Translation

    Target ORF information:

    RefSeq Version XM_313043.5
    Organism Anopheles gambiae str. PEST
    Definition Anopheles gambiae str. PEST AGAP004159-RA (AgaP_AGAP004159), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_313043.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGGTGCAGG GCATCGACCA TCTGCGCGAT CCGCGCCTCA ACAAGGGGCT GGCGTTCACG 
    CTGGAGGAGC GCCAAATCCT CGGCATCCAC GGGCTGCAGC CGGCCCGCTT CAAGTCGCAG
    GAGGAGCAGC TGGAGCTGTG CCGCATCTCG ATCTCGCGCT ACCAGGAAGA CCTCAACAAG
    TACCTGTACC TGGTCGATTT GCAGGACCGC AACGAGCGGC TGTTCTTCCG ACTGATCTCG
    GAGGACGTGG AAAAGATGAT GCCGATCGTC TACACGCCCA CCGTCGGGCT GGCCTGCCAA
    AAGTTCGGCC TGATCTATCG GCGACCGCGC GGCCTGTTCG TGACGATTAA CGACCGGGGT
    CACGTGTTCG ACGTGCTGCG CAACTGGCCG GAACCGGACG TGCGCGCGAT CGTCGTGACG
    GACGGCGAGC GCATCCTGGG CCTGGGCGAT CTTGGCGCGT GCGGCATGGG AATCCCGGTC
    GGCAAGCTGG CGCTGTACAC CGCGCTCGCC GGTATCCCGC CGCACCAGTG TCTGCCGATC
    GTGATCGACG TCGGCACGAA CAACAAGGAC CTGCTGGAGG ATCCGCTGTA CATTGGGCTG
    CGGCACCAGC GCGTGCAGGG CAAGGAGTAC GACGAGTTTA TCGACGAGTT CATGCAGGCG
    GTCGTGAAGC GGTACGGCCA GAACACGCTC ATCCAGTTCG AGGACTTTGG CAACCACAAC
    GCGTTCCGCT TTCTGGACAA GTACCGCAAC ACCTACTGCA CGTTCAACGA CGACATCCAG
    GGCACGGCCT CGGTCGCGGT CGCGGGGATG CTGGCCGCGA AGCGCATCAC CAACAAGCGC
    ATCTCGGACA ACACGTTCCT GTTTCTGGGT GCGGGCGAGG CGGCCGTCGG CATTGCCGAT
    CTGGTGGTGA AAGCGATGCA GGCGGAGGGC ACGGGCCTGC AGGAGGCACG CGACAAGATC
    TGGATGTTCG ACATCGACGG TCTGCTGGCG AAGGGCCGCC CGGAGGGTCG GCTAGGCGGG
    CACAAAGCGT ACTATGCCAA AGATCACGGC GTGATGAAGA ACTTTGCCGA CGTGGTGAAG
    GAGGTGAAAC CGTCGGTGCT GATCGGTGCG TCCGCGGCGG GCGGCGCGTT TACGCCGGAG
    ATTCTGCAGG CCATGGGCCA GTTCAACGAG CGGCCGATCA TTTTCGCCTT GTCCAACCCG
    ACCTCCAAGG CGGAGTGTAC GGCACAGGCG GCCTATGATA ATACCGAGGT ACGTTTGGGT
    CGGTGCATTT TTGCGTCGGG GTCTCCGTTC CCGCCGGTGC AGTATGGCGG AAAGACGTTC
    ATCACCGGCC AGGGCAACAA CGCGTACATC TTCCCGGGCG TCGCTTTGGG TGTCATCGTT
    ACCGGCACGC ACCACATCCC GGAGGACATG TTCCTTATCG CTGCCCAGGT CGTCGCGGAC
    CACGTATCCG AGGCGGACCT CGAGAAGGGT TCGCTCTACC CTCCGCTAAG TGCCATTAAG
    GAGTGTTCGA TGGATATCGC AGTCGGCGTT ACGAACTACG CATATCAGAA GGGTCTCGCC
    TCGACCTACC CCGAGCCGGA GGACAAGAAG TCGTACATTG AGTCGCACCT GTACAACTAC
    AACTACCAGA GCGCCATGCC CGTCACCTGG CCATGGCCGA AGCAGCACGA ATCATCGAAA
    ACGCGGGAAA TCAATCCGAC CAAACTGCAG GCATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    The Anopheles gambiae genome: an update.
    Trends in parasitology20(2)49-52(2004 Feb)
    Mongin E,Louis C,Holt RA,Birney E,Collins FH


    The genome sequence of the malaria mosquito Anopheles gambiae.
    Science (New York, N.Y.)298(5591)129-49(2002 Oct)
    Holt RA,Subramanian GM,Halpern A,Sutton GG,Charlab R,Nusskern DR,Wincker P,Clark AG,Ribeiro JM,Wides R,Salzberg SL,Loftus B,Yandell M,Majoros WH,Rusch DB,Lai Z,Kraft CL,Abril JF,Anthouard V,Arensburger P,Atkinson PW,Baden H,de Berardinis V,Baldwin D,Benes V,Biedler J,Blass C,Bolanos R,Boscus D,Barnstead M,Cai S,Center A,Chaturverdi K,Christophides GK,Chrystal MA,Clamp M,Cravchik A,Curwen V,Dana A,Delcher A,Dew I,Evans CA,Flanigan M,Grundschober-Freimoser A,Friedli L,Gu Z,Guan P,Guigo R,Hillenmeyer ME,Hladun SL,Hogan JR,Hong YS,Hoover J,Jaillon O,Ke Z,Kodira C,Kokoza E,Koutsos A,Letunic I,Levitsky A,Liang Y,Lin JJ,Lobo NF,Lopez JR,Malek JA,McIntosh TC,Meister S,Miller J,Mobarry C,Mongin E,Murphy SD,O'Brochta DA,Pfannkoch C,Qi R,Regier MA,Remington K,Shao H,Sharakhova MV,Sitter CD,Shetty J,Smith TJ,Strong R,Sun J,Thomasova D,Ton LQ,Topalis P,Tu Z,Unger MF,Walenz B,Wang A,Wang J,Wang M,Wang X,Woodford KJ,Wortman JR,Wu M,Yao A,Zdobnov EM,Zhang H,Zhao Q,Zhao S,Zhu SC,Zhimulev I,Coluzzi M,della Torre A,Roth CW,Louis C,Kalush F,Mural RJ,Myers EW,Adams MD,Smith HO,Broder S,Gardner MJ,Fraser CM,Birney E,Bork P,Brey PT,Venter JC,Weissenbach J,Kafatos FC,Collins FH,Hoffman SL