TEP6 cDNA ORF clone, Anopheles gambiae str. PEST

The following TEP6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TEP6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OAh06209 XM_318490.2
Latest version!
Anopheles gambiae str. PEST AGAP010814-RA (TEP6), partial mRNA. pcDNA3.1-C-(k)DYK or customized vector 20 $713.30
$1019.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OAh06209
    Clone ID Related Accession (Same CDS sequence) XM_318490.2
    Accession Version XM_318490.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 3996bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-04-25
    Organism Anopheles gambiae str. PEST
    Product AGAP010814-PA
    Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NT_078267). On Sep 28, 2011 this sequence version replaced XM_318490.1. COMPLETENESS: incomplete on both ends.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    ATGTCTAAAT CAATCATGTG GAAGTGTATT AGGTCACGAA TATTAATGGT GATAATCGTC 
    ATAGGTGCCG CTCATGGGCT ACTGGTTGTG GGTCCGAAAT TTATACGGGC CAACCAGGAA
    TACACTCTGG TGATCAGCAA CTTTAACTCA CAGCTAAGCA AAGTGGACCT GCTGTTAAAA
    CTGGAAGGCG AAACTGATAA TGGTTTAAGC GTTCTGAACG TTACCAAGAT GGTTGACGTG
    CGACGTAATA TGAACCGAAT GATCAACTTC AATATGCCTG AGGATCTGAC GGCTGGAAAC
    TACAAAATAA CTATCGATGG ACAGCGTGGC TTCAGCTTTC ACAAGGAGGC AGAGCTGGTG
    TATCTCAGCA AATCGATATC GGGGCTAATA CAGGTCGATA AGCCCGTATT TAAACCTGGG
    GATACGGTGA ACTTCCGTGT GATCGTGCTG GACACGGAGC TGAAACCGCC GGCGAGGGTC
    AAGTCGGTTT ATGTAACTAT ACGAGATCCT CAGCGCAATG TGATTCGCAA ATGGTCCACG
    GCAAAACTGT ATGCCGGTGT GTTCGAGAGC GATCTACAGA TAGCGCCTAC TCCAATGCTC
    GGGGTCTGGA ATATCTCGGT GGAGGTGGAA GGAGAAGAGC TTGTGTCAAA GACGTTTGAG
    GTGAAGGAGT ACGTGTTGTC AACGTTCGAC GTGCAGGTCA TGCCATCGGT GATTCCACTG
    GAAGAGCATC AAGCTGTGAA TCTTACAATC GAAGCGAACT ATCACTTTGG TAAGCCAGTG
    CAAGGAGTGG CCAAGGTGGA GCTGTACCTA GACGACGATA AGCTAAAACT GAAAAAAGAG
    CTGACTGTGT ACGGAAAGGG CCAGGTAGAG TTGCGCTTTG ACAATTTTGC AATGGATGCG
    GATCAGCAGG ATGTACCAGT GAAGGTGTCG TTCGTCGAGC AGTACACAAA TCGTACGGTG
    GTCAAACAGT CACAAATCAC GGTATATAGG TATGCGTACC GAGTAGAGTT GATAAAAGAG
    AGTCCACAGT TTCGTCCGGG ACTCCCGTTC AAATGTGCGC TTCAGTTTAC ACACCATGAT
    GGAACACCGG CTAAAGGCAT TAGCGGTAAG GTAGAGGTAT CCGATGTACG ATTCGAAACG
    ACAACAACGA GTGATAACGA TGGATTGATT AAGCTCGAGC TGCAACCAAG TGAGGGTACT
    GAACAACTCA GTATTCACTT CAATGCTGTT GATGGATTCT TTTTTTATGA AGATGTGAAT
    AAGGTAGAAA CGGTTACGGA TGCGTATATT AAACTGGAGC TGAAATCACC CATCAAACGG
    AACAAATTGA TGCGTTTCAT GGTGACGTGC ACGGAGCGCA TGACATTCTT CGTGTACTAT
    GTCATGTCAA AGGGCAATAT CATCGATGCA GGCTTCATGC GACCCAACAA GCAAACGAAG
    TACCTGTTGC AGCTGAACGC AACAGAAAAG ATGATTCCGA AGGCGAAAAT CCTTGTCGCT
    ACCCTAGTGA ATCGTACGAT GGTGAACGAT ATTGTGGATA TTGATTTCCA AGGGTTTCGT
    AGTAACTTTG ATTTAAGCAT TGACGAGCAA GAGATCAAGC CGGGACGTCA AATCGAGCTG
    AGCATGTCTG GACGCCCTGG AGCGTACGTT GGGCTGGCCG CGTATGACAA AGCCTTGCTG
    CTGTTCAACA AGAACCACGA CCTGTTCTGG GAGGACATTG GGCAGGTGTT TGACGGGTTC
    CATTCATATG ACACAAATGA ATTCGACCTG TTTGACAACA TGGGCTTGTT TGCCAGAATG
    GATAATATTA TGTTTGATCA ATCCAATGAT AAATCGGCAC GCAGTGGACA GCAGGCGGAC
    GGAACAGTGT TTAGGAAACA GTTTCTAGAA TCATGGTTGT GGAAGACTGC GATCATTGGA
    AATTCCGGTA CTCTCAAGCT GATTGAGGTT GTACCGGATA CAACGACCAC CTGGTATCTG
    ACGGGCTTCT CGATCGATCC CGTGTACGGG TTGGGTATCG TTAAGAAACC GATCGAGATC
    ACAACAGTGC AGCCGTTTGT CGTTATGGAA AGCTTGCCGT ATTCGATCAA GAGAGGTGAG
    GCGATCGAGA TACAATTTAT TCTTATCAGC AACCTTCAAG AAGAGTACAC CGTTGACGTG
    ACGCTGTATA ATGAGAACAA CGAGATGGAG TTCCTCGGAC GTTCGATTTC AAACGTAAGC
    TACACCAAAT CGGTGAGTGT ACCTCCAAAG GTAGGAAAAC CTGTATCATT TCTAGTGAAA
    GCAAAGAAGC TCGGTGAGAT GATGGTTCGT GTGAAAGCAT CTATAGCCAA TGAGCTTGCA
    ACGGATGCAC TGGAGAAGGT GATACGGGTC ACGCCAGAAA GCTTGGTACA GTCAGGAGTA
    GAATCGTTCG GATTTTTCAT GGACACGCAT CAGAATCGAA CGTTCTTGGT GAATCCGAAC
    ATTGATAAAA AGGCCGATAA TGGATCGATA GCGATCGAGC TTAGAGTTAA TCCCAACTTA
    CTGATTAAGG TCAAAGAAAA TTTAAATGAT CTTCGTACTG TATCGCCTAC ATGTAAGAAT
    GTGATAAGAT TGGCACTTAA TTTTGCTGTC GCTGATTATC TGATTGCATG TGGACCCAAA
    GAACAGAATC TTCCCGAAAA TGCCGTCGAT GCGTTGAGTA AAGAATATAT GTTGCTAATG
    ACTTGCTTGA ATTCGGATAG TTCATTTGAT AGCGTGCAGA ATATTGTTAG CAATATATTT
    TACACTGCAT TTGTAGCCAA TACGCTGGAT ACTGCACCCA AGAATGTGTG CCAGACAAGT
    AATGTTAAAT TAGAGAAAGC ATTTGACTGG CTTGCCTCTC GACAGCAACG TTTCGGAAGT
    TTCAGAGAAA TCGAAACCGA TCTGCACTAT ACACGTAGTG AAATAGCATT GACATCCTAC
    GTATTGGCAT CAATGCTAGA GAACGAAAGC GCCAAAGTGA AGCACGCTGT GGTGATAGAA
    AAGGGCATGT GGTTTCTGAG CAATCAATTC GATTTAATCA CAAGCGCAAA TGATTTGGCG
    ATAGTGACCT ATGCGATGAT GTTGTACGGG CACTGGCGAA AGGACGCTGC GTTCGAAAAG
    CTGATCGATA TGTCAACCAT CACAAATAAT GGAGCGGAAC GATATTGGAA AACGTCGAAC
    AGCGTAGAGG CAACGTCTTA CGCTTTGCTA TCGCATGTGT TATCCAACAA GTTGCTAGCA
    GCTTTGCCAA TAATGCGTTG GCTAGTGAAT CAGAAAAGCG AAATAGACAG TGTTTCTGGC
    CAAGAAACTA CCTATTTGCG TCTCAAAGCA CTGTCCAGGA TGACAAACAA GATATCTCCA
    TCCCGGAATG ACTATATGGT ACAGCTAAAG TACAAGCAAA GTACGCGATT GTTGCGTTTT
    GATTCATACA GAAATATGAT ACAAAACATT ACCACACCGC AAGACTTAAG GAAGATTAAA
    ATAACAGTTG AGGGTATTGG GGTTGGGCTC CTGGAGGTGA TGTATAAATA CAGATTGAAT
    CTCGTGAACT TTGAGCATCG ATTCCAGCTA GACTTACAGA AACAGAACAC AAGCTCCGAC
    AACGAGCTAA GGCTGAAGGT GTGTGCCAAC TATATCCCCA CTTTGCGTGA CAGCCACTCA
    AACATGACAC TAATCGAGGT GACATTACCG AGCGGTTACG TTGTCGATCG CAATCCGATC
    AGCGAGCAGA CGACGGTGAA TCCGATACAG AACATGGAAA TTCGTTACGG TGGCACTTCA
    GTCGTTCTGT ACTACTACAA TATGGGCACC GAGCGTAACT GTTTTACCGT GACTGCGTAC
    AGACGCTTTA AGGTCGCATT GAAGCGTCCA GCGTATGTTG TTGTGTACGA TTATTATGAT
    ACAAATCAGA ACGCCATCAA AGTGTACGAA ATGGACAAGC AGAATGTGTG CGAAATCTGC
    GACGCTTGCG GCTGTACCGC AGAGTGCAAG ACATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_318490.2
    CDS1..3996
    Translation

    Target ORF information:

    RefSeq Version XM_318490.2
    Organism Anopheles gambiae str. PEST
    Definition Anopheles gambiae str. PEST AGAP010814-RA (TEP6), partial mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_318490.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    ATGTCTAAAT CAATCATGTG GAAGTGTATT AGGTCACGAA TATTAATGGT GATAATCGTC 
    ATAGGTGCCG CTCATGGGCT ACTGGTTGTG GGTCCGAAAT TTATACGGGC CAACCAGGAA
    TACACTCTGG TGATCAGCAA CTTTAACTCA CAGCTAAGCA AAGTGGACCT GCTGTTAAAA
    CTGGAAGGCG AAACTGATAA TGGTTTAAGC GTTCTGAACG TTACCAAGAT GGTTGACGTG
    CGACGTAATA TGAACCGAAT GATCAACTTC AATATGCCTG AGGATCTGAC GGCTGGAAAC
    TACAAAATAA CTATCGATGG ACAGCGTGGC TTCAGCTTTC ACAAGGAGGC AGAGCTGGTG
    TATCTCAGCA AATCGATATC GGGGCTAATA CAGGTCGATA AGCCCGTATT TAAACCTGGG
    GATACGGTGA ACTTCCGTGT GATCGTGCTG GACACGGAGC TGAAACCGCC GGCGAGGGTC
    AAGTCGGTTT ATGTAACTAT ACGAGATCCT CAGCGCAATG TGATTCGCAA ATGGTCCACG
    GCAAAACTGT ATGCCGGTGT GTTCGAGAGC GATCTACAGA TAGCGCCTAC TCCAATGCTC
    GGGGTCTGGA ATATCTCGGT GGAGGTGGAA GGAGAAGAGC TTGTGTCAAA GACGTTTGAG
    GTGAAGGAGT ACGTGTTGTC AACGTTCGAC GTGCAGGTCA TGCCATCGGT GATTCCACTG
    GAAGAGCATC AAGCTGTGAA TCTTACAATC GAAGCGAACT ATCACTTTGG TAAGCCAGTG
    CAAGGAGTGG CCAAGGTGGA GCTGTACCTA GACGACGATA AGCTAAAACT GAAAAAAGAG
    CTGACTGTGT ACGGAAAGGG CCAGGTAGAG TTGCGCTTTG ACAATTTTGC AATGGATGCG
    GATCAGCAGG ATGTACCAGT GAAGGTGTCG TTCGTCGAGC AGTACACAAA TCGTACGGTG
    GTCAAACAGT CACAAATCAC GGTATATAGG TATGCGTACC GAGTAGAGTT GATAAAAGAG
    AGTCCACAGT TTCGTCCGGG ACTCCCGTTC AAATGTGCGC TTCAGTTTAC ACACCATGAT
    GGAACACCGG CTAAAGGCAT TAGCGGTAAG GTAGAGGTAT CCGATGTACG ATTCGAAACG
    ACAACAACGA GTGATAACGA TGGATTGATT AAGCTCGAGC TGCAACCAAG TGAGGGTACT
    GAACAACTCA GTATTCACTT CAATGCTGTT GATGGATTCT TTTTTTATGA AGATGTGAAT
    AAGGTAGAAA CGGTTACGGA TGCGTATATT AAACTGGAGC TGAAATCACC CATCAAACGG
    AACAAATTGA TGCGTTTCAT GGTGACGTGC ACGGAGCGCA TGACATTCTT CGTGTACTAT
    GTCATGTCAA AGGGCAATAT CATCGATGCA GGCTTCATGC GACCCAACAA GCAAACGAAG
    TACCTGTTGC AGCTGAACGC AACAGAAAAG ATGATTCCGA AGGCGAAAAT CCTTGTCGCT
    ACCCTAGTGA ATCGTACGAT GGTGAACGAT ATTGTGGATA TTGATTTCCA AGGGTTTCGT
    AGTAACTTTG ATTTAAGCAT TGACGAGCAA GAGATCAAGC CGGGACGTCA AATCGAGCTG
    AGCATGTCTG GACGCCCTGG AGCGTACGTT GGGCTGGCCG CGTATGACAA AGCCTTGCTG
    CTGTTCAACA AGAACCACGA CCTGTTCTGG GAGGACATTG GGCAGGTGTT TGACGGGTTC
    CATTCATATG ACACAAATGA ATTCGACCTG TTTGACAACA TGGGCTTGTT TGCCAGAATG
    GATAATATTA TGTTTGATCA ATCCAATGAT AAATCGGCAC GCAGTGGACA GCAGGCGGAC
    GGAACAGTGT TTAGGAAACA GTTTCTAGAA TCATGGTTGT GGAAGACTGC GATCATTGGA
    AATTCCGGTA CTCTCAAGCT GATTGAGGTT GTACCGGATA CAACGACCAC CTGGTATCTG
    ACGGGCTTCT CGATCGATCC CGTGTACGGG TTGGGTATCG TTAAGAAACC GATCGAGATC
    ACAACAGTGC AGCCGTTTGT CGTTATGGAA AGCTTGCCGT ATTCGATCAA GAGAGGTGAG
    GCGATCGAGA TACAATTTAT TCTTATCAGC AACCTTCAAG AAGAGTACAC CGTTGACGTG
    ACGCTGTATA ATGAGAACAA CGAGATGGAG TTCCTCGGAC GTTCGATTTC AAACGTAAGC
    TACACCAAAT CGGTGAGTGT ACCTCCAAAG GTAGGAAAAC CTGTATCATT TCTAGTGAAA
    GCAAAGAAGC TCGGTGAGAT GATGGTTCGT GTGAAAGCAT CTATAGCCAA TGAGCTTGCA
    ACGGATGCAC TGGAGAAGGT GATACGGGTC ACGCCAGAAA GCTTGGTACA GTCAGGAGTA
    GAATCGTTCG GATTTTTCAT GGACACGCAT CAGAATCGAA CGTTCTTGGT GAATCCGAAC
    ATTGATAAAA AGGCCGATAA TGGATCGATA GCGATCGAGC TTAGAGTTAA TCCCAACTTA
    CTGATTAAGG TCAAAGAAAA TTTAAATGAT CTTCGTACTG TATCGCCTAC ATGTAAGAAT
    GTGATAAGAT TGGCACTTAA TTTTGCTGTC GCTGATTATC TGATTGCATG TGGACCCAAA
    GAACAGAATC TTCCCGAAAA TGCCGTCGAT GCGTTGAGTA AAGAATATAT GTTGCTAATG
    ACTTGCTTGA ATTCGGATAG TTCATTTGAT AGCGTGCAGA ATATTGTTAG CAATATATTT
    TACACTGCAT TTGTAGCCAA TACGCTGGAT ACTGCACCCA AGAATGTGTG CCAGACAAGT
    AATGTTAAAT TAGAGAAAGC ATTTGACTGG CTTGCCTCTC GACAGCAACG TTTCGGAAGT
    TTCAGAGAAA TCGAAACCGA TCTGCACTAT ACACGTAGTG AAATAGCATT GACATCCTAC
    GTATTGGCAT CAATGCTAGA GAACGAAAGC GCCAAAGTGA AGCACGCTGT GGTGATAGAA
    AAGGGCATGT GGTTTCTGAG CAATCAATTC GATTTAATCA CAAGCGCAAA TGATTTGGCG
    ATAGTGACCT ATGCGATGAT GTTGTACGGG CACTGGCGAA AGGACGCTGC GTTCGAAAAG
    CTGATCGATA TGTCAACCAT CACAAATAAT GGAGCGGAAC GATATTGGAA AACGTCGAAC
    AGCGTAGAGG CAACGTCTTA CGCTTTGCTA TCGCATGTGT TATCCAACAA GTTGCTAGCA
    GCTTTGCCAA TAATGCGTTG GCTAGTGAAT CAGAAAAGCG AAATAGACAG TGTTTCTGGC
    CAAGAAACTA CCTATTTGCG TCTCAAAGCA CTGTCCAGGA TGACAAACAA GATATCTCCA
    TCCCGGAATG ACTATATGGT ACAGCTAAAG TACAAGCAAA GTACGCGATT GTTGCGTTTT
    GATTCATACA GAAATATGAT ACAAAACATT ACCACACCGC AAGACTTAAG GAAGATTAAA
    ATAACAGTTG AGGGTATTGG GGTTGGGCTC CTGGAGGTGA TGTATAAATA CAGATTGAAT
    CTCGTGAACT TTGAGCATCG ATTCCAGCTA GACTTACAGA AACAGAACAC AAGCTCCGAC
    AACGAGCTAA GGCTGAAGGT GTGTGCCAAC TATATCCCCA CTTTGCGTGA CAGCCACTCA
    AACATGACAC TAATCGAGGT GACATTACCG AGCGGTTACG TTGTCGATCG CAATCCGATC
    AGCGAGCAGA CGACGGTGAA TCCGATACAG AACATGGAAA TTCGTTACGG TGGCACTTCA
    GTCGTTCTGT ACTACTACAA TATGGGCACC GAGCGTAACT GTTTTACCGT GACTGCGTAC
    AGACGCTTTA AGGTCGCATT GAAGCGTCCA GCGTATGTTG TTGTGTACGA TTATTATGAT
    ACAAATCAGA ACGCCATCAA AGTGTACGAA ATGGACAAGC AGAATGTGTG CGAAATCTGC
    GACGCTTGCG GCTGTACCGC AGAGTGCAAG ACATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    The Anopheles gambiae genome: an update.
    Trends in parasitology20(2)49-52(2004 Feb)
    Mongin E,Louis C,Holt RA,Birney E,Collins FH


    The genome sequence of the malaria mosquito Anopheles gambiae.
    Science (New York, N.Y.)298(5591)129-49(2002 Oct)
    Holt RA,Subramanian GM,Halpern A,Sutton GG,Charlab R,Nusskern DR,Wincker P,Clark AG,Ribeiro JM,Wides R,Salzberg SL,Loftus B,Yandell M,Majoros WH,Rusch DB,Lai Z,Kraft CL,Abril JF,Anthouard V,Arensburger P,Atkinson PW,Baden H,de Berardinis V,Baldwin D,Benes V,Biedler J,Blass C,Bolanos R,Boscus D,Barnstead M,Cai S,Center A,Chaturverdi K,Christophides GK,Chrystal MA,Clamp M,Cravchik A,Curwen V,Dana A,Delcher A,Dew I,Evans CA,Flanigan M,Grundschober-Freimoser A,Friedli L,Gu Z,Guan P,Guigo R,Hillenmeyer ME,Hladun SL,Hogan JR,Hong YS,Hoover J,Jaillon O,Ke Z,Kodira C,Kokoza E,Koutsos A,Letunic I,Levitsky A,Liang Y,Lin JJ,Lobo NF,Lopez JR,Malek JA,McIntosh TC,Meister S,Miller J,Mobarry C,Mongin E,Murphy SD,O'Brochta DA,Pfannkoch C,Qi R,Regier MA,Remington K,Shao H,Sharakhova MV,Sitter CD,Shetty J,Smith TJ,Strong R,Sun J,Thomasova D,Ton LQ,Topalis P,Tu Z,Unger MF,Walenz B,Wang A,Wang J,Wang M,Wang X,Woodford KJ,Wortman JR,Wu M,Yao A,Zdobnov EM,Zhang H,Zhao Q,Zhao S,Zhu SC,Zhimulev I,Coluzzi M,della Torre A,Roth CW,Louis C,Kalush F,Mural RJ,Myers EW,Adams MD,Smith HO,Broder S,Gardner MJ,Fraser CM,Birney E,Bork P,Brey PT,Venter JC,Weissenbach J,Kafatos FC,Collins FH,Hoffman SL