ADRB3 cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADRB3
Entrez Gene ID	100294559
Full Name	adrenoceptor beta 3
Synonyms	B3AR
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001159757.1	NP_001153229.1	beta-3 adrenergic receptor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Halplotypes of the ovine ADRB3 gene (ADRB3) and their association with post-weaning growth in New Zealand Suffolk sheep.
Yang G, Zhou H, Forrest RH, Fang Q, Luo Y, Hickford JG
Molecular biology reports40(8)4805-10(2013 Aug)

SNP variation in ADRB3 gene reflects the breed difference of sheep populations.
Wu J, Qiao L, Liu J, Yuan Y, Liu W
Molecular biology reports39(8)8395-403(2012 Aug)

Extended haplotype analysis of ovine ADRB3 using polymerase chain reaction single strand conformational polymorphism on two regions of the gene.
Yang G, Hickford JG, Zhou H, Fang Q, Forrest RH
DNA and cell biology30(7)445-8(2011 Jul)

Polymorphism of the ovine beta3-adrenergic receptor gene (ADRB3) and its association with wool mean staple strength and yield.
Forrest RH, Itenge-Mweza TO, McKenzie GW, Zhou H, Frampton CM, Hickford JG
Animal genetics40(6)958-62(2009 Dec)

Extensive diversity of the ADRB3 gene in Chinese sheep identified by PCR-SSCP.
Yang G, Zhou H, Hu J, Luo Y, Hickford JG
Biochemical genetics47(7-8)498-502(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The effects of the ovine ADRB3 haplotypes on weaning-weight and post-weaning growth confirm that they could be used as a candidate gene-marker for improving sheep growth.
Title: Halplotypes of the ovine ADRB3 gene (ADRB3) and their association with post-weaning growth in New Zealand Suffolk sheep.

SNPs of ovine ADRB3 gene can reflect the breed difference and within- and between-population variations, and to a great extent, the breed relationship.
Title: SNP variation in ADRB3 gene reflects the breed difference of sheep populations.

study suggests that ovine ADRB3 is highly polymorphic and that the extended haplotype analysis through the promoter, 5'UTR, coding sequence, intron, and 3'UTR needs to be performed to define the full extent of variation in this gene
Title: Extended haplotype analysis of ovine ADRB3 using polymerase chain reaction single strand conformational polymorphism on two regions of the gene.

Results from mixed-effects models and half-sib analyses suggest that some ADRB3 alleles have a negative impact on some wool traits, in particular mean staple strength, whereas other alleles appear to have a positive impact.
Title: Polymorphism of the ovine beta3-adrenergic receptor gene (ADRB3) and its association with wool mean staple strength and yield.

ADRB3 polymorphism in the Hu, Tan, small-tailed Han, and Tibet breeds of Chinese sheep
Title: Extensive diversity of the ADRB3 gene in Chinese sheep identified by PCR-SSCP.

The following ADRB3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADRB3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSm00134	NM_001159757.1 Latest version!	Ovis aries adrenoceptor beta 3 (ADRB3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADRB3 ( NM_001159757.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001153229.1 Ovis aries adrenoceptor beta 3 (ADRB3), mRNA.

Price & Availability↑

CloneID	OSm00134
Clone ID Related Accession (Same CDS sequence)	NM_001159757.1
Accession Version	NM_001159757.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Ovis aries(sheep)
Product	beta-3 adrenergic receptor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF314204.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA104494976, SAMEA104495029 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCCGT GGCCTCCCGG GAACAGCTCT CTGACCCCGT GGCCAGATAT CCCCACCCTG 
GCACCCAATA CTGCCAACGC GAGTGGGCTG CCAGGGGTGC CCTGGGCGGT GGCGCTGGCG 
GGGGCGCTGC TGGCGCTAGC GGTGCTGGCC ACCGTGGGAG GCAACCTGCT GGTAATCGTG 
GCCATCGCCC GGACGCCGAG ACTCCAGACC ATGACCAACG TGTTCGTGAC TTCGCTGGCC 
ACAGCCGACC TCGTGGTGGG GCTTCTGGTC GTGCCCCCGG GGGCCACGTT GGCGCTGACC 
GGCCACTGGC CCCTGGGCGT CACCGGTTGC GAGCTGTGGA CCTCGGTGGA CGTGCTGTGT 
GTGACCGCCA GCATCGAAAC CCTGTGCGCC CTGGCGGTGG ACCGCTACCT GGCCGTGACC 
AACCCGCTGC GCTACGGCGC ACTGGTCACC AAACGCCGCG CCCGAGCAGC CGTGGTGCTG 
GTGTGGGTCG TGTCCGCCGC GGTGTCGTTT GCGCCCATCA TGAGCAAATG GTGGCGCGTT 
GGGGCAGATG CCGAGGCGCA GCGTTGCCAC TCCAACCCGC GCTGCTGCAC CTTCGCCTCC 
AACATGCCCT ACGCGCTGCT CTCCTCCTCG GTCTCCTTCT ATCTTCCGCT TCTGGTGATG 
CTCTTCGTCT ACGCGCGAGT TTTCGTGGTG GCTACGCGCC AGCTGCGCTT GCTGCGCCGG 
GAGCTGGGTC GCTTCCCGCC AGAGGAGTCT CCGCCGGCTC CTTCTCGCTC CGGCTCCCCT 
GGGCCGGCGG GGCCGTACGC CTCGCCTGCG GGGGTGCCCT CCTACGGCCG GCGGCCGGCG 
CGCCTTCTGC CTCTGCGGGA ACACCGCGCC CTGCGCACCT TGGGGCTCAT CATGGGAACC 
TTCACTCTCT GCTGGTTGCC TTTCTTTGTG GTCAACGTGG TGCGCGCCCT CGGGGGCCCC 
TCTCTGGTGT CCGGCCCCAC TTTCCTCGCC CTTAACTGGC TGGGCTATGC CAATTCTGCC 
TTCAACCCGC TCATCTACTG CCGCAGCCCG GACTTTCGGA GCGCCTTCCG CCGCCTGCTG 
TGTCGTTGCC CGCCGGAGGA GCACCTCGCC GCTGCCTCCC CGCCCCGAGC CCCCTCCGGC 
GCCCCCACGG TCCTGACCAG CCCCGCTGGC CCCAGGCAGC CCTCACCGCT CGACGGGGCT 
TCCTGCGGAC TTTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153229.1
CDS	204..1421
Translation	MAPWPPGNSSLTPWPDIPTLAPNTANASGLPGVPWAVALAGALLALAVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGHWPLGVTGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRARAAVVLVWVVSAAVSFAPIMSKWWRVGADAEAQRCHSNPRCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRRELGRFPPEESPPAPSRSGSPGPAGPYASPAGVPSYGRRPARLLPLREHRALRTLGLIMGTFTLCWLPFFVVNVVRALGGPSLVSGPTFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCPPEEHLAAASPPRAPSGAPTVLTSPAGPRQPSPLDGASCGLS

Target ORF information:

RefSeq Version	NM_001159757.1
Organism	Ovis aries(sheep)
Definition	Ovis aries adrenoceptor beta 3 (ADRB3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159757.1

ORF Insert Sequence:

ATGGCTCCGT GGCCTCCCGG GAACAGCTCT CTGACCCCGT GGCCAGATAT CCCCACCCTG 
GCACCCAATA CTGCCAACGC GAGTGGGCTG CCAGGGGTGC CCTGGGCGGT GGCGCTGGCG 
GGGGCGCTGC TGGCGCTAGC GGTGCTGGCC ACCGTGGGAG GCAACCTGCT GGTAATCGTG 
GCCATCGCCC GGACGCCGAG ACTCCAGACC ATGACCAACG TGTTCGTGAC TTCGCTGGCC 
ACAGCCGACC TCGTGGTGGG GCTTCTGGTC GTGCCCCCGG GGGCCACGTT GGCGCTGACC 
GGCCACTGGC CCCTGGGCGT CACCGGTTGC GAGCTGTGGA CCTCGGTGGA CGTGCTGTGT 
GTGACCGCCA GCATCGAAAC CCTGTGCGCC CTGGCGGTGG ACCGCTACCT GGCCGTGACC 
AACCCGCTGC GCTACGGCGC ACTGGTCACC AAACGCCGCG CCCGAGCAGC CGTGGTGCTG 
GTGTGGGTCG TGTCCGCCGC GGTGTCGTTT GCGCCCATCA TGAGCAAATG GTGGCGCGTT 
GGGGCAGATG CCGAGGCGCA GCGTTGCCAC TCCAACCCGC GCTGCTGCAC CTTCGCCTCC 
AACATGCCCT ACGCGCTGCT CTCCTCCTCG GTCTCCTTCT ATCTTCCGCT TCTGGTGATG 
CTCTTCGTCT ACGCGCGAGT TTTCGTGGTG GCTACGCGCC AGCTGCGCTT GCTGCGCCGG 
GAGCTGGGTC GCTTCCCGCC AGAGGAGTCT CCGCCGGCTC CTTCTCGCTC CGGCTCCCCT 
GGGCCGGCGG GGCCGTACGC CTCGCCTGCG GGGGTGCCCT CCTACGGCCG GCGGCCGGCG 
CGCCTTCTGC CTCTGCGGGA ACACCGCGCC CTGCGCACCT TGGGGCTCAT CATGGGAACC 
TTCACTCTCT GCTGGTTGCC TTTCTTTGTG GTCAACGTGG TGCGCGCCCT CGGGGGCCCC 
TCTCTGGTGT CCGGCCCCAC TTTCCTCGCC CTTAACTGGC TGGGCTATGC CAATTCTGCC 
TTCAACCCGC TCATCTACTG CCGCAGCCCG GACTTTCGGA GCGCCTTCCG CCGCCTGCTG 
TGTCGTTGCC CGCCGGAGGA GCACCTCGCC GCTGCCTCCC CGCCCCGAGC CCCCTCCGGC 
GCCCCCACGG TCCTGACCAG CCCCGCTGGC CCCAGGCAGC CCTCACCGCT CGACGGGGCT 
TCCTGCGGAC TTTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Halplotypes of the ovine ADRB3 gene (ADRB3) and their association with post-weaning growth in New Zealand Suffolk sheep.
Molecular biology reports40(8)4805-10(2013 Aug)
Yang G,Zhou H,Forrest RH,Fang Q,Luo Y,Hickford JG

SNP variation in ADRB3 gene reflects the breed difference of sheep populations.
Molecular biology reports39(8)8395-403(2012 Aug)
Wu J,Qiao L,Liu J,Yuan Y,Liu W

Extended haplotype analysis of ovine ADRB3 using polymerase chain reaction single strand conformational polymorphism on two regions of the gene.
DNA and cell biology30(7)445-8(2011 Jul)
Yang G,Hickford JG,Zhou H,Fang Q,Forrest RH

Polymorphism of the ovine beta3-adrenergic receptor gene (ADRB3) and its association with wool mean staple strength and yield.
Animal genetics40(6)958-62(2009 Dec)
Forrest RH,Itenge-Mweza TO,McKenzie GW,Zhou H,Frampton CM,Hickford JG

Extensive diversity of the ADRB3 gene in Chinese sheep identified by PCR-SSCP.
Biochemical genetics47(7-8)498-502(2009 Aug)
Yang G,Zhou H,Hu J,Luo Y,Hickford JG

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ADRB3 cDNA ORF clone, Ovis aries(sheep)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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