ADAMTS10 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAMTS10
Entrez Gene ID	611267
Full Name	ADAM metallopeptidase with thrombospondin type 1 motif 10
General protein information	Preferred Names ADAM metallopeptidase with thrombospondin type 1 motif 10 Names A disintegrin and metalloproteinase with thrombospondin motifs 10
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_022406268.1	XP_022261976.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
XM_022406266.1	XP_022261974.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
XM_022406265.1	XP_022261973.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
XM_849227.4	XP_854320.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
NM_001284481.1	NP_001271410.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor
XM_022406267.1	XP_022261975.1	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ADAMTS10	NP_112219.3
Bos taurus (cattle)	ADAMTS10	NP_001192679.1
Gallus gallus (chicken)	ADAMTS10	XP_001232250.1
Canis lupus familiaris (dog)	ADAMTS10	XP_854320.1
	ADAMTS10	XP_001095217.1
Xenopus tropicalis (tropical clawed frog)	adamts10	XP_002938612.2
Pan troglodytes (chimpanzee)	ADAMTS10	XP_001159753.1
Mus musculus (house mouse)	Adamts10	NP_766207.2
Rattus norvegicus (Norway rat)	Adamts10	NP_001258374.1
Danio rerio (zebrafish)	adamts10	NP_001116746.1

Gene Ontology
Bibliography

Related articles in PubMed

Changes in posterior scleral collagen microstructure in canine eyes with an ADAMTS10 mutation.
Boote C, Palko JR, Sorensen T, Mohammadvali A, Elsheikh A, Kom?romy AM, Pan X, Liu J
Molecular vision22503-17(2016)

Influence of Age on Ocular Biomechanical Properties in a Canine Glaucoma Model with ADAMTS10 Mutation.
Palko JR, Morris HJ, Pan X, Harman CD, Koehl KL, Gelatt KN, Plummer CE, Kom?romy AM, Liu J
PloS one11(6)e0156466(2016)

Biomechanical properties and correlation with collagen solubility profile in the posterior sclera of canine eyes with an ADAMTS10 mutation.
Palko JR, Iwabe S, Pan X, Agarwal G, Kom?romy AM, Liu J
Investigative ophthalmology & visual science54(4)2685-95(2013 Apr)

Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.
Kuchtey J, Olson LM, Rinkoski T, Mackay EO, Iverson TM, Gelatt KN, Haines JL, Kuchtey RW
PLoS genetics7(2)e1001306(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Significant alterations in the posterior scleral collagen microstructure are present before the onset of clinical glaucoma in ADAMTS10 mutant dogs.
Title: Changes in posterior scleral collagen microstructure in canine eyes with an ADAMTS10 mutation.

Despite a mutation that affects the extracellular matrix and a chronic intraocular pressure elevation in the affected dogs, age-associated scleral stiffening and loss of mechanical damping were still prominent and had a similar rate of change as in the normal dogs.
Title: Influence of Age on Ocular Biomechanical Properties in a Canine Glaucoma Model with ADAMTS10 Mutation.

An inherently weaker and biochemically distinct posterior sclera was observed in dogs with the G661R missense mutation in ADAMTS10 before clinical indications of optic nerve damage.
Title: Biomechanical properties and correlation with collagen solubility profile in the posterior sclera of canine eyes with an ADAMTS10 mutation.

The Gly661Arg variant in ADAMTS10 found in the primary open angle glaucoma Beagles suggests that altered processing of extracellular matrix and/or defects in microfibril structure or function may be involved in raising intraocular pressure.
Title: Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.

The following ADAMTS10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAMTS10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe22287	NM_001284481.1 Latest version!	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OCe22287	XM_849227.4 Latest version!	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OCe22287	XM_022406267.1 Latest version!	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OCe22287	XM_022406266.1 Latest version!	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OCe22287	XM_022406268.1 Latest version!	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OCe22287	XM_022406265.1 Latest version!	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAMTS10 ( NM_001284481.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001271410.1 Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), mRNA.

Price & Availability↑

CloneID	OCe22287
Clone ID Related Accession (Same CDS sequence)	XM_022406268.1 , XM_022406266.1 , XM_022406265.1 , XM_849227.4 , NM_001284481.1 , XM_022406267.1
Accession Version	NM_001284481.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Canis lupus familiaris(dog)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JX306093.1. ##Evidence-Data-START## Transcript exon combination :: JX306093.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001271410.1
CDS	1..3312
Translation	MAPACQILRWALTLGLGLTFEVIHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPAPRRQRRGTRPTTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGAQGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYRNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPAIGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGEQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDHTQSLEALGPINASLIVMVLARTELAALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSSDHRATLPPAHCPPAAKPPATMRCNLRRCPPARWVTGEWGECSAQCGIGQQQRAVRCSSHTGQPSRECAEALRPPATQQCEAKCDSAPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR

Target ORF information:

RefSeq Version	NM_001284481.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001284481.1

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_022406268.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022261976.1 Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OCe22287
Clone ID Related Accession (Same CDS sequence)	XM_022406268.1 , XM_022406266.1 , XM_022406265.1 , XM_849227.4 , NM_001284481.1 , XM_022406267.1
Accession Version	XM_022406268.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006602.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022261976.1
CDS	461..3772
Translation	MAPACQILRWALTLGLGLTFEVIHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPAPRRQRRGTRPTTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGAQGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYRNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPAIGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGEQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDHTQSLEALGPINASLIVMVLARTELAALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSSDHRATLPPAHCPPAAKPPATMRCNLRRCPPARWVTGEWGECSAQCGIGQQQRAVRCSSHTGQPSRECAEALRPPATQQCEAKCDSAPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR

Target ORF information:

RefSeq Version	XM_022406268.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022406268.1

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_022406266.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022261974.1 Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X2, mRNA.

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CloneID	OCe22287
Clone ID Related Accession (Same CDS sequence)	XM_022406268.1 , XM_022406266.1 , XM_022406265.1 , XM_849227.4 , NM_001284481.1 , XM_022406267.1
Accession Version	XM_022406266.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006602.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022261974.1
CDS	202..3513
Translation	MAPACQILRWALTLGLGLTFEVIHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPAPRRQRRGTRPTTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGAQGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYRNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPAIGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGEQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDHTQSLEALGPINASLIVMVLARTELAALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSSDHRATLPPAHCPPAAKPPATMRCNLRRCPPARWVTGEWGECSAQCGIGQQQRAVRCSSHTGQPSRECAEALRPPATQQCEAKCDSAPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR

Target ORF information:

RefSeq Version	XM_022406266.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022406266.1

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_022406265.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022261973.1 Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe22287
Clone ID Related Accession (Same CDS sequence)	XM_022406268.1 , XM_022406266.1 , XM_022406265.1 , XM_849227.4 , NM_001284481.1 , XM_022406267.1
Accession Version	XM_022406265.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006602.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022261973.1
CDS	308..3619
Translation	MAPACQILRWALTLGLGLTFEVIHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPAPRRQRRGTRPTTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGAQGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYRNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPAIGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGEQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDHTQSLEALGPINASLIVMVLARTELAALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSSDHRATLPPAHCPPAAKPPATMRCNLRRCPPARWVTGEWGECSAQCGIGQQQRAVRCSSHTGQPSRECAEALRPPATQQCEAKCDSAPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR

Target ORF information:

RefSeq Version	XM_022406265.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022406265.1

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_849227.4 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_854320.1 Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe22287
Clone ID Related Accession (Same CDS sequence)	XM_022406268.1 , XM_022406266.1 , XM_022406265.1 , XM_849227.4 , NM_001284481.1 , XM_022406267.1
Accession Version	XM_849227.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726096.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_849227.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_854320.1
CDS	691..4002
Translation	MAPACQILRWALTLGLGLTFEVIHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPAPRRQRRGTRPTTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGAQGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYRNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPAIGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGEQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDHTQSLEALGPINASLIVMVLARTELAALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSSDHRATLPPAHCPPAAKPPATMRCNLRRCPPARWVTGEWGECSAQCGIGQQQRAVRCSSHTGQPSRECAEALRPPATQQCEAKCDSAPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR

Target ORF information:

RefSeq Version	XM_849227.4
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_849227.4

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAMTS10 ( XM_022406267.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022261975.1 Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X3, mRNA.

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CloneID	OCe22287
Clone ID Related Accession (Same CDS sequence)	XM_022406268.1 , XM_022406266.1 , XM_022406265.1 , XM_849227.4 , NM_001284481.1 , XM_022406267.1
Accession Version	XM_022406267.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006602.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022261975.1
CDS	464..3775
Translation	MAPACQILRWALTLGLGLTFEVIHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPAPRRQRRGTRPTTESRLFYKVAAPSTHFLLNLTRSPRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADEEEYLIEPLQGGPKGAQGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNRSGHGNAIPENGVANHDTAVLITRYDICIYRNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPAIGYEEVVWIPKGSVHIFIQDLNLSLSHLALKGEQESLLLEGLPGTPQPHRLPLAGTTFQLRQGPDHTQSLEALGPINASLIVMVLARTELAALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHHCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACQGPACPPEWAALDWSECTPSCGPGLRHRVVLCKSSDHRATLPPAHCPPAAKPPATMRCNLRRCPPARWVTGEWGECSAQCGIGQQQRAVRCSSHTGQPSRECAEALRPPATQQCEAKCDSAPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGR

Target ORF information:

RefSeq Version	XM_022406267.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ADAM metallopeptidase with thrombospondin type 1 motif 10 (ADAMTS10), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022406267.1

ORF Insert Sequence:

ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCACCC TGGGGCTGGG CCTCACATTC 
GAAGTCATAC ATGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG 
ATCGCCTTCC CCACTCGAGT GGACCACAAT GGGGCACTGC TGGCCTTCTC ACCCCCGGCT 
CCCCGGAGGC AGCGTCGGGG CACAAGGCCA ACGACAGAGT CCCGCCTCTT CTACAAGGTG 
GCTGCACCCA GCACCCACTT CCTGCTGAAC CTAACCCGCA GCCCCCGCCT TCTAGCAGGG 
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCGT GGCAGAGGGC TGCCCGGCCC 
CACTGCCTCT ACGCCGGCCA CTTGCAGGGC CAGGCCGGCA GCTCCCACGT GGCCATCAGC 
ACCTGTGGGG GCCTGCACGG CCTGATCGTG GCAGATGAAG AAGAATATTT GATCGAGCCC 
CTGCAAGGTG GGCCCAAAGG GGCCCAGGGC CCAGAGGAGA GTGGCCCCCA TGTGGTGTAC 
AAGCGCTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGACGAGAAA 
CCGTGGAAGG GGCGGCCGTG GTGGCTGCGC ACCCTGAAGC CGCCACCTGC CAGGCCCCTG 
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGCT CGGTCAGCCG AGAGCGCTAC 
GTGGAGACCC TGGTGGTGGC CGACAAGATG ATGGTGGCCT ACCACGGGCG CCGAGACGTG 
GAACAGTACG TGCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG 
GGAAACATCG TTAATATCCT GGTGACACGC CTCATCCTGC TCACGGAGGA CCAGCCCACC 
CTGGAGATCA CCCACCACGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC 
ATCGTGAACC GCAGCGGCCA TGGCAACGCC ATTCCGGAGA ACGGTGTGGC CAACCATGAC 
ACAGCGGTGC TCATCACGCG CTATGACATC TGCATCTATA GGAACAAACC CTGTGGCACT 
CTAGGCCTGG CCCCCGTGGG TGGGATGTGC GAGCGCGAGC GGAGCTGCAG CATTAACGAG 
GACATCGGCC TGGCCACCGC CTTCACCATC GCCCATGAGA TTGGACACAC GTTTGGCATG 
AACCACGACG GCGTGGGCAA CAGCTGCGGG GCCCGCGGCC AGGACCCGGC CAAGCTCATG 
GCCGCCCACA TCACCATGAA GACCAACCCT TTCGTGTGGT CATCCTGCAG CCGCGACTAC 
ATCACCAGCT TTCTGGACTC GGGCCTGGGG CTGTGCCTGA ACAACCGGCC CCCCAGACAG 
GACTTCGTGT ACCCAACGGT GGCACCTGGC CAGGCCTATG ACGCAGATGA ACAGTGCCGC 
TTCCAACATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG 
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATTC CAGCCGCCGA GGGCACGCTG 
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAGC GCGTGTGTGT CCCCTTCGGG 
TCGCGGCCGG AGGGCGTGGA CGGGGCCTGG GGCCCGTGGA CCCCGTGGGG CGACTGCAGC 
CGGACGTGCG GCGGCGGCGT GTCCTCCTCC AGCCGGCACT GCGACAGCCC CAGGCCAACA 
ATCGGAGGCA AGTACTGCCT GGGTGAGAGG CGGCGACACC GCTCCTGCAA CACCGACGAC 
TGTCCCCCAG GCTCCCAGGA CTTCAGGGAA ATGCAGTGCT CTGAATTTGA CAGCGTCCCC 
TTCCGTGGAA AATTCTACAC GTGGAAGACC TACCGAGGAG GGGGCGTGAA GGCCTGTTCA 
CTCACATGCC TGGCCGAAGG CTTCAACTTC TACACGGAGA GGGCAGCGGC CGTAGTGGAC 
GGGACACCCT GCCGCCCGGA CACAGTGGAC ATTTGTGTCA GTGGCGAGTG CAAGCATGTG 
GGCTGTGACC GGGTCCTGGG CTCCGACCTG AGGGAGGACA AGTGCCGGGT TTGCGGTGGT 
GACGGCAGCG CCTGTGAAAC CATCGAGGGG GTCTTCAGCC CAGCTTCACC TGCAATCGGG 
TATGAGGAAG TCGTCTGGAT CCCCAAAGGC TCCGTCCACA TCTTCATCCA GGACCTGAAC 
CTCTCCCTCA GTCACCTGGC TCTGAAGGGG GAGCAGGAGT CCCTGCTGCT GGAGGGGCTG 
CCCGGGACCC CGCAGCCCCA CCGCCTGCCC CTGGCTGGGA CCACCTTTCA GCTGCGGCAG 
GGACCAGATC ACACGCAGAG CCTAGAAGCC CTGGGACCCA TAAATGCGTC TCTCATCGTC 
ATGGTGCTGG CCCGGACTGA GCTGGCTGCC CTCCGCTACC GCTTCAACGC GCCCATCGCC 
CGAGATGCAC TGCCCCCCTA CTCCTGGCAC TACGCACCCT GGACCAAGTG CTCGGCCCAG 
TGTGCCGGCG GCAGCCAGGT GCAGGCCGTG GAGTGCCGCA ATCAGCTGGA CAGCTCGGCC 
GTGGCTCCCC ACCATTGCAG TGCCCACAGC AAACTGCCCA AGAGGCAGCG CGCCTGCAAC 
ACAGAGCCCT GTCCGCCCGA CTGGGTGGTA GGCAACTGGT CGCGGTGCAG CCGCAGCTGT 
GATGCGGGTG TGCGCAGCCG CTCCGTCGTG TGCCAGCGCC GCGTGTCAGC CGCCGAGGAG 
AAGGCGCTGG ACGACAGCGC GTGCCCGCAG CCGCGCCCGC CGGTCCTGGA GGCCTGCCAA 
GGCCCCGCCT GCCCTCCCGA GTGGGCCGCC CTGGACTGGT CGGAGTGCAC CCCGAGCTGC 
GGGCCCGGCC TCCGCCACCG CGTCGTCCTG TGCAAGAGCT CGGACCACCG CGCCACGCTG 
CCCCCCGCGC ACTGCCCGCC CGCAGCCAAG CCTCCGGCCA CCATGCGTTG CAACTTGCGC 
CGCTGTCCCC CGGCTCGCTG GGTGACGGGC GAGTGGGGCG AGTGCTCCGC GCAGTGTGGC 
ATCGGGCAGC AGCAGCGCGC CGTGCGCTGC TCCAGCCACA CGGGCCAGCC GTCCCGCGAG 
TGCGCAGAGG CTCTGCGGCC CCCGGCCACG CAGCAGTGCG AAGCCAAGTG CGACAGCGCG 
CCCCCCGGGG ACGGCCCCGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG 
GTGCTCAAAT TTCAGTTCTG CAGCAGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC 
CAGGGCCGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Changes in posterior scleral collagen microstructure in canine eyes with an ADAMTS10 mutation.
Molecular vision22503-17(2016)
Boote C,Palko JR,Sorensen T,Mohammadvali A,Elsheikh A,Kom?romy AM,Pan X,Liu J

Influence of Age on Ocular Biomechanical Properties in a Canine Glaucoma Model with ADAMTS10 Mutation.
PloS one11(6)e0156466(2016)
Palko JR,Morris HJ,Pan X,Harman CD,Koehl KL,Gelatt KN,Plummer CE,Kom?romy AM,Liu J

Biomechanical properties and correlation with collagen solubility profile in the posterior sclera of canine eyes with an ADAMTS10 mutation.
Investigative ophthalmology & visual science54(4)2685-95(2013 Apr)
Palko JR,Iwabe S,Pan X,Agarwal G,Kom?romy AM,Liu J

Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.
PLoS genetics7(2)e1001306(2011 Feb)
Kuchtey J,Olson LM,Rinkoski T,Mackay EO,Iverson TM,Gelatt KN,Haines JL,Kuchtey RW

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ADAMTS10 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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