Gene Symbol | INS |
Entrez Gene ID | 483665 |
Full Name | insulin |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
ORF » Species Summary » Canis lupus familiaris » INS cDNA ORF clone
Gene Symbol | INS |
Entrez Gene ID | 483665 |
Full Name | insulin |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
mRNA | Protein | Name |
---|---|---|
NM_001130093.2 | NP_001123565.1 | insulin precursor |
NM_001130093.1 | NP_001123565.1 | insulin precursor |
Pan troglodytes (chimpanzee) | INS | NP_001008996.1 |
Mus musculus (house mouse) | Ins2 | NP_032413.1 |
Gallus gallus (chicken) | INS | NP_990553.1 |
Danio rerio (zebrafish) | ins | NP_571131.1 |
Xenopus tropicalis (tropical clawed frog) | ins | NP_001093706.1 |
Rattus norvegicus (Norway rat) | Ins2 | NP_062003.1 |
Canis lupus familiaris (dog) | INS | NP_001123565.1 |
Homo sapiens (human) | INS | NP_000198.1 |
Interleukin-6 and insulin incrase and nitric oxide and adiponectin decrease in blind dogs with pituitary-dependent hyperadrenocorticism.
Cabrera Blatter MF, del Prado B, Miceli DD, Gomez N, Ivanic J, Di Tollo B, Gallelli MF, Castillo VA
Research in veterinary science93(3)1195-202(2012 Dec)
Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.
Edgerton DS, Ramnanan CJ, Grueter CA, Johnson KM, Lautz M, Neal DW, Williams PE, Cherrington AD
Diabetes58(12)2766-75(2009 Dec)
Cloning and nucleotide sequence analysis of the dog insulin gene. Coded amino acid sequence of canine preproinsulin predicts an additional C-peptide fragment.
Kwok SC, Chan SJ, Steiner DF
The Journal of biological chemistry258(4)2357-63(1983 Feb)
Species variation in the amino acid sequence of insulin.
Smith LF
The American journal of medicine40(5)662-6(1966 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The etiology of blindness in dogs with pituitary dependent hypercortisolism, including the role of adiponectin, interleukin 6, insulin, and nitric oxide, is reported.
Title: Interleukin-6 and insulin incrase and nitric oxide and adiponectin decrease in blind dogs with pituitary-dependent hyperadrenocorticism.
Gluconeogenic flux can be rapidly inhibited by high insulin levels in canines.
Title: Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.
The following INS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00517 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130093.1 | |
Accession Version | NM_001130093.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2012-07-20 | |
Organism | Canis lupus familiaris(Dog) | |
Product | insulin precursor | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AAEX02030224.1. On Jul 16, 2008 this sequence version replaced XM_540786.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
1 | ATGGCCCTCT GGATGCGCCT CCTGCCCCTG CTGGCCCTGC TGGCCCTCTG GGCGCCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123565.1 |
CDS | 31..363 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130093.1 |
1 | ATGGCCCTCT GGATGCGCCT CCTGCCCCTG CTGGCCCTGC TGGCCCTCTG GGCGCCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe282402 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130093.2 | |
Accession Version | NM_001130093.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-20 | |
Organism | Canis lupus familiaris(dog) | |
Product | insulin precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AAEX03011552.1. On Jun 30, 2017 this sequence version replaced NM_001130093.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DN360896.1, DN321843.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN07419822 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCCTCT GGATGCGCCT CCTGCCCCTG CTGGCCCTGC TGGCCCTCTG GGCGCCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123565.1 |
CDS | 31..363 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130093.2 |
1 | ATGGCCCTCT GGATGCGCCT CCTGCCCCTG CTGGCCCTGC TGGCCCTCTG GGCGCCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interleukin-6 and insulin incrase and nitric oxide and adiponectin decrease in blind dogs with pituitary-dependent hyperadrenocorticism. |
Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo. |
Cloning and nucleotide sequence analysis of the dog insulin gene. Coded amino acid sequence of canine preproinsulin predicts an additional C-peptide fragment. |
Species variation in the amino acid sequence of insulin. |