Gene Symbol | FOLH1 |
Entrez Gene ID | 476775 |
Full Name | folate hydrolase (prostate-specific membrane antigen) 1 |
Synonyms | PSMA |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » FOLH1 cDNA ORF clone
Gene Symbol | FOLH1 |
Entrez Gene ID | 476775 |
Full Name | folate hydrolase (prostate-specific membrane antigen) 1 |
Synonyms | PSMA |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
XM_014122421.1 | XP_013977896.1 | glutamate carboxypeptidase 2 isoform X1 |
NM_001271778.1 | NP_001258707.1 | glutamate carboxypeptidase 2 |
XM_022407423.1 | XP_022263131.1 | glutamate carboxypeptidase 2 isoform X1 |
Canis lupus familiaris (dog) | FOLH1 | NP_001258707.1 |
Bos taurus (cattle) | FOLH1 | NP_001095328.1 |
FOLH1 | XP_001096141.2 | |
Mus musculus (house mouse) | Folh1 | NP_058050.3 |
Neurospora crassa | NCU03108 | XP_964967.2 |
Pan troglodytes (chimpanzee) | LOC451475 | XP_001137174.1 |
Kluyveromyces lactis | KLLA0D16588g | XP_453792.1 |
Xenopus tropicalis (tropical clawed frog) | folh1 | XP_002936599.2 |
Rattus norvegicus (Norway rat) | Folh1 | NP_476533.1 |
Gallus gallus (chicken) | FOLH1 | XP_417205.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_15288 | XP_003716179.1 |
Danio rerio (zebrafish) | naalad2 | NP_956571.1 |
Cloning and characterization of canine prostate-specific membrane antigen.
Schmidt S, Fracasso G, Colombatti M, Naim HY
The Prostate73(6)642-50(2013 May)
Histopathological and immunohistochemical characterization of canine prostate cancer.
Lai CL, van den Ham R, van Leenders G, van der Lugt J, Mol JA, Teske E
The Prostate68(5)477-88(2008 Apr)
Apical transport and folding of prostate-specific membrane antigen occurs independent of glycan processing.
Castelletti D, Fracasso G, Alfalah M, Cingarlini S, Colombatti M, Naim HY
The Journal of biological chemistry281(6)3505-12(2006 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Canine PSMA reveals similar characteristics to human PSMA rendering this protein useful as a translational model for investigations of prostate cancer as well as a suitable antigen for targeted therapy studies in dogs.
Title: Cloning and characterization of canine prostate-specific membrane antigen.
Immunohistochemically, 50% or more of the canine prostate cancer cases showed expression of PSA, PSMA, UPIII, CK7, CK5, CK14, and CK18.
Title: Histopathological and immunohistochemical characterization of canine prostate cancer.
acquisition of folding determinants in the Golgi is an essential prerequisite for protein trafficking and sorting of PSMA
Title: Apical transport and folding of prostate-specific membrane antigen occurs independent of glycan processing.
The following FOLH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FOLH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe34058 | |
Clone ID Related Accession (Same CDS sequence) | NM_001271778.1 | |
Accession Version | NM_001271778.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-27 | |
Organism | Canis lupus familiaris(dog) | |
Product | glutamate carboxypeptidase 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HE820284.1. On Nov 21, 2012 this sequence version replaced XM_533980.3. ##Evidence-Data-START## Transcript exon combination :: HE820284.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTGGAACC CCCTTCGCGA GGGCGACTCG ACCTTCGCCG CCTGGCGCCG CCCGCGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001258707.1 |
CDS | 16..2271 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001271778.1 |
1 | ATGTGGAACC CCCTTCGCGA GGGCGACTCG ACCTTCGCCG CCTGGCGCCG CCCGCGCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe295841 | |
Clone ID Related Accession (Same CDS sequence) | XM_022407423.1 | |
Accession Version | XM_022407423.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | glutamate carboxypeptidase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006603.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGAAGG CATTTTTGGA TGAATTGAAA GCTGAGAACA TCAAGAGGTT CTTATATAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_022263131.1 |
CDS | 205..2289 |
Translation |
Target ORF information:
Target ORF information:
|
XM_022407423.1 |
1 | ATGAAGAAGG CATTTTTGGA TGAATTGAAA GCTGAGAACA TCAAGAGGTT CTTATATAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe41999 | |
Clone ID Related Accession (Same CDS sequence) | XM_014122421.1 | |
Accession Version | XM_014122421.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2658bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | glutamate carboxypeptidase 2 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726097.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 10% of CDS bases ##RefSeq-Attributes-END## |
1 | ATGAGTGGAT CTCCATACCT GCTGGCCAGA ATCTTACAAG TTTATATTGA GGCATTAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013977896.1 |
CDS | 1..2658 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014122421.1 |
1 | ATGAGTGGAT CTCCATACCT GCTGGCCAGA ATCTTACAAG TTTATATTGA GGCATTAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cloning and characterization of canine prostate-specific membrane antigen. |
Histopathological and immunohistochemical characterization of canine prostate cancer. |
Apical transport and folding of prostate-specific membrane antigen occurs independent of glycan processing. |