Gene Symbol | CDC42 |
Entrez Gene ID | 403934 |
Full Name | cell division cycle 42 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » CDC42 cDNA ORF clone
Gene Symbol | CDC42 |
Entrez Gene ID | 403934 |
Full Name | cell division cycle 42 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003254.2 | NP_001003254.1 | cell division control protein 42 homolog precursor |
Pan troglodytes (chimpanzee) | CDC42 | XP_003951460.1 |
Canis lupus familiaris (dog) | CDC42 | NP_001003254.1 |
Saccharomyces cerevisiae (baker's yeast) | CDC42 | NP_013330.1 |
Neurospora crassa | NCU06454 | XP_957345.2 |
Xenopus tropicalis (tropical clawed frog) | cdc42 | NP_001017070.1 |
Homo sapiens (human) | CDC42 | NP_001034891.1 |
Danio rerio (zebrafish) | cdc42l | NP_956159.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00466 | XP_003718598.1 |
LOC100424807 | XP_002803768.1 | |
Caenorhabditis elegans (roundworm) | cdc-42 | NP_495598.1 |
Oryza sativa (rice) | Os01g0229400 | NP_001042486.1 |
Anopheles gambiae (African malaria mosquito) | CDC42_ANOGA | XP_003436126.1 |
Kluyveromyces lactis | KLLA0A04213g | XP_451186.1 |
Eremothecium gossypii | AGOS_AGL093W | NP_986573.1 |
Bos taurus (cattle) | CDC42 | NP_001039797.1 |
Gallus gallus (chicken) | CDC42 | NP_990379.1 |
Drosophila melanogaster (fruit fly) | Cdc42 | NP_001245764.1 |
Schizosaccharomyces pombe (fission yeast) | cdc42 | NP_593536.1 |
Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function.
Raya-Sandino A, Castillo-Kauil A, Dom?nguez-Calder?n A, Alarc?n L, Flores-Benitez D, Cuellar-Perez F, L?pez-Bayghen B, Ch?vez-Mungu?a B, V?zquez-Prado J, Gonz?lez-Mariscal L
Biochimica et biophysica acta1864(10)1714-1733(2017 10)
Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42.
Lu R, Wilson JM
Scientific reports638249(2016 Nov)
Early herpes simplex virus type 1 infection is dependent on regulated Rac1/Cdc42 signalling in epithelial MDCKII cells.
Hoppe S, Schelhaas M, Jaeger V, Liebig T, Petermann P, Knebel-M?rsdorf D
The Journal of general virology87(Pt 12)3483-94(2006 Dec)
The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle.
Tang DD, Zhang W, Gunst SJ
The Journal of biological chemistry280(24)23380-9(2005 Jun)
The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle.
Tang DD, Gunst SJ
The Journal of biological chemistry279(50)51722-8(2004 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Silencing tight junction protein ZO-2 alters epithelial cytoarchitecture.ZO-2 silencing increases RhoA activity through GEF-H1 recruitment to cell borders.ZO-2 silencing activates Cdc42 and triggers mitotic spindle disorientation. ZO-2 silencing increases Rac1 and cofilin activity and lamellipodia formation.
Title: Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function.
these results provide the first evidence for a role of Rac1/Cdc42 signalling during early HSV-1 infection and suggest a mechanism relying on virus-induced regulation of Rac1/Cdc42 activities.
Title: Early herpes simplex virus type 1 infection is dependent on regulated Rac1/Cdc42 signalling in epithelial MDCKII cells.
CrkII plays a critical role in the regulation of N-WASp activation, actin polymerization, and active tension generation in tracheal smooth muscle, by regulating the activation of cdc42 [CrkII]
Title: The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle.
Cdc42 activation regulates active tension development and actin polymerization during smooth muscle contractile stimulation
Title: The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle.
CDC42 regulates anoikis.
Title: Regulation of anoikis by Cdc42 and Rac1.
The following CDC42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00020 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003254.2 | |
Accession Version | NM_001003254.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-06 | |
Organism | Canis lupus familiaris(dog) | |
Product | cell division control protein 42 homolog precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z49944.1. On Sep 18, 2015 this sequence version replaced NM_001003254.1. ##Evidence-Data-START## Transcript exon combination :: Z49944.1, DN422370.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2240594 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCAGACAA TTAAGTGCGT TGTTGTGGGC GATGGTGCCG TTGGTAAAAC ATGTCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003254.1 |
CDS | 14..589 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003254.2 |
1 | ATGCAGACAA TTAAGTGCGT TGTTGTGGGC GATGGTGCCG TTGGTAAAAC ATGTCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. |
Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42. |
Early herpes simplex virus type 1 infection is dependent on regulated Rac1/Cdc42 signalling in epithelial MDCKII cells. |
The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle. |
The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle. |