Gene Symbol | HTR2A |
Entrez Gene ID | 403882 |
Full Name | 5-hydroxytryptamine receptor 2A |
Synonyms | 5-HT-2,5-HT-2A,5-HTR2A |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » HTR2A cDNA ORF clone
Gene Symbol | HTR2A |
Entrez Gene ID | 403882 |
Full Name | 5-hydroxytryptamine receptor 2A |
Synonyms | 5-HT-2,5-HT-2A,5-HTR2A |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001005869.1 | NP_001005869.1 | 5-hydroxytryptamine receptor 2A |
HTR2A | NP_001028138.1 | |
Rattus norvegicus (Norway rat) | Htr2a | NP_058950.1 |
Danio rerio (zebrafish) | LOC560808 | XP_689300.6 |
Danio rerio (zebrafish) | si:dkey-276l13.4 | XP_688270.2 |
Caenorhabditis elegans (roundworm) | ser-1 | NP_001024728.1 |
Pan troglodytes (chimpanzee) | HTR2A | XP_522752.2 |
Canis lupus familiaris (dog) | HTR2A | NP_001005869.1 |
Mus musculus (house mouse) | Htr2a | NP_766400.1 |
Homo sapiens (human) | HTR2A | NP_000612.1 |
Bos taurus (cattle) | HTR2A | NP_001001157.1 |
Gallus gallus (chicken) | HTR2A | XP_004938757.1 |
Xenopus tropicalis (tropical clawed frog) | htr2a | XP_002935159.1 |
Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease.
Cremer SE, Moesgaard SG, Rasmussen CE, Zois NE, Falk T, Reimann MJ, Cirera S, Aupperle H, Oyama MA, Olsen LH
Research in veterinary science100197-206(2015 Jun)
The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line.
Bracha S, Viall A, Goodall C, Stang B, Ruaux C, Seguin B, Chappell PE
BMC veterinary research9251(2013 Dec)
Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis.
Przyklenk K, Frelinger AL 3rd, Linden MD, Whittaker P, Li Y, Barnard MR, Adams J, Morgan M, Al-Shamma H, Michelson AD
Journal of thrombosis and haemostasis : JTH8(2)331-40(2010 Feb)
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog.
Bonaventure P, Nepomuceno D, Miller K, Chen J, Kuei C, Kamme F, Tran DT, Lovenberg TW, Liu C
European journal of pharmacology513(3)181-92(2005 Apr)
Sequencing of canine 5-hydroxytriptamine receptor (5-HTR) 1B, 2A, 2C genes and identification of polymorphisms in the 5-HTR1B gene.
Masuda K, Hashizume C, Ogata N, Kikusui T, Takeuchi Y, Mori Y
The Journal of veterinary medical science66(8)965-72(2004 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
There was a positive association between gene expression of the 5-HT2BR in the mitral valve and myocardium and clinical presence of canine myxomatous mitral valve disease. The same association was not found for the 5-HT2AR.
Title: Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease.
functional existence in osteosarcoma cell line, indicating that intracellular second messenger signal coupling is different between normal and malignant cells
Title: The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line.
5HT2A receptor inhibition with APD791, even when initiated after the onset of recurrent thrombosis, improves coronary patency in the in vivo canine model.
Title: Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis.
The following HTR2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HTR2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00012 | |
Clone ID Related Accession (Same CDS sequence) | NM_001005869.1 | |
Accession Version | NM_001005869.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1413bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Canis lupus familiaris(dog) | |
Product | 5-hydroxytryptamine receptor 2A | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB193092.1. On Jan 12, 2005 this sequence version replaced XM_534122.1. ##Evidence-Data-START## Transcript exon combination :: AB193092.1, AY832858.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATGTCC TCTTTGAGGA TAATGCTCCT TTGAGCCCAA CCACCAGCTC CTTAATGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001005869.1 |
CDS | 1..1413 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001005869.1 |
1 | ATGGATGTCC TCTTTGAGGA TAATGCTCCT TTGAGCCCAA CCACCAGCTC CTTAATGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease. |
The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line. |
Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis. |
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog. |
Sequencing of canine 5-hydroxytriptamine receptor (5-HTR) 1B, 2A, 2C genes and identification of polymorphisms in the 5-HTR1B gene. |