Gene Symbol | GUSB |
Entrez Gene ID | 403831 |
Full Name | glucuronidase beta |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » GUSB cDNA ORF clone
Gene Symbol | GUSB |
Entrez Gene ID | 403831 |
Full Name | glucuronidase beta |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
XM_014114125.2 | XP_013969600.1 | beta-glucuronidase isoform X2 |
XM_014114125.1 | XP_013969600.1 | beta-glucuronidase isoform X2 |
NM_001003191.1 | NP_001003191.1 | beta-glucuronidase precursor |
XM_014114126.1 | XP_013969601.1 | beta-glucuronidase isoform X3 |
XM_014114126.2 | XP_013969601.1 | beta-glucuronidase isoform X3 |
XM_005620897.2 | XP_005620954.1 | beta-glucuronidase isoform X1 |
XM_005620897.3 | XP_005620954.1 | beta-glucuronidase isoform X1 |
Mus musculus (house mouse) | Gusb | NP_034498.1 |
Rattus norvegicus (Norway rat) | Gusb | NP_058711.2 |
Drosophila melanogaster (fruit fly) | CG15117 | NP_725851.1 |
Caenorhabditis elegans (roundworm) | CELE_Y105E8B.9 | NP_493548.1 |
Bos taurus (cattle) | GUSB | NP_001076905.1 |
Pan troglodytes (chimpanzee) | GUSB | XP_001138883.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011859 | XP_320660.4 |
Homo sapiens (human) | GUSB | NP_000172.2 |
Canis lupus familiaris (dog) | GUSB | NP_001003191.1 |
Gallus gallus (chicken) | GUSB | NP_001034405.1 |
Danio rerio (zebrafish) | LOC100535236 | XP_005165070.1 |
Danio rerio (zebrafish) | gusb | XP_700122.6 |
Xenopus tropicalis (tropical clawed frog) | gusb | XP_002935849.2 |
A novel GUSB mutation in Brazilian terriers with severe skeletal abnormalities defines the disease as mucopolysaccharidosis VII.
Hyt?nen MK, Arumilli M, Lappalainen AK, Kallio H, Snellman M, Sainio K, Lohi H
PloS one7(7)e40281(2012)
Construction and characterization of an eightfold redundant dog genomic bacterial artificial chromosome library.
Li R, Mignot E, Faraco J, Kadotani H, Cantanese J, Zhao B, Lin X, Hinton L, Ostrander EA, Patterson DF, de Jong PJ
Genomics58(1)9-17(1999 May)
Cloning of the canine beta-glucuronidase cDNA, mutation identification in canine MPS VII, and retroviral vector-mediated correction of MPS VII cells.
Ray J, Bouvet A, DeSanto C, Fyfe JC, Xu D, Wolfe JH, Aguirre GD, Patterson DF, Haskins ME, Henthorn PS
Genomics48(2)248-53(1998 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a novel genetic defect in the Brazilian Terrier breed causing a congenital skeletal dysplasia
Title: A novel GUSB mutation in Brazilian terriers with severe skeletal abnormalities defines the disease as mucopolysaccharidosis VII.
The following GUSB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GUSB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe34164 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003191.1 | |
Accession Version | NM_001003191.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Canis lupus familiaris(dog) | |
Product | beta-glucuronidase precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF019759.1. ##Evidence-Data-START## Transcript exon combination :: AF019759.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTCTCGGG GGCCGGCGGG GGCCTGGGTA GCGCTCGGCC CGCTGCTTTG GACCTGCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003191.1 |
CDS | 63..2018 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003191.1 |
1 | ATGTCTCGGG GGCCGGCGGG GGCCTGGGTA GCGCTCGGCC CGCTGCTTTG GACCTGCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe07336 | |
Clone ID Related Accession (Same CDS sequence) | XM_005620897.2 , XM_005620897.3 | |
Accession Version | XM_005620897.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | beta-glucuronidase isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726061.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005620897.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAGTTC CGTCCAGCTT CAATGATGTG GGCCAGGATA GGCAGCTGCG CAGCTTTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005620954.1 |
CDS | 196..1923 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005620897.2 |
1 | ATGCCAGTTC CGTCCAGCTT CAATGATGTG GGCCAGGATA GGCAGCTGCG CAGCTTTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe07336 | |
Clone ID Related Accession (Same CDS sequence) | XM_005620897.2 , XM_005620897.3 | |
Accession Version | XM_005620897.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | beta-glucuronidase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006588.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005620897.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAGTTC CGTCCAGCTT CAATGATGTG GGCCAGGATA GGCAGCTGCG CAGCTTTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005620954.1 |
CDS | 243..1970 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005620897.3 |
1 | ATGCCAGTTC CGTCCAGCTT CAATGATGTG GGCCAGGATA GGCAGCTGCG CAGCTTTGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe36795 | |
Clone ID Related Accession (Same CDS sequence) | XM_014114125.2 , XM_014114125.1 | |
Accession Version | XM_014114125.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | beta-glucuronidase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006588.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_014114125.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCGT GGTACCCCAA GGGTTACTTC GTCCAGAACA CATACTTTGA CTTCTTCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013969600.1 |
CDS | 133..1521 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014114125.2 |
1 | ATGCCATCGT GGTACCCCAA GGGTTACTTC GTCCAGAACA CATACTTTGA CTTCTTCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe36795 | |
Clone ID Related Accession (Same CDS sequence) | XM_014114125.2 , XM_014114125.1 | |
Accession Version | XM_014114125.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | beta-glucuronidase isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726061.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCGT GGTACCCCAA GGGTTACTTC GTCCAGAACA CATACTTTGA CTTCTTCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013969600.1 |
CDS | 83..1471 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014114125.1 |
1 | ATGCCATCGT GGTACCCCAA GGGTTACTTC GTCCAGAACA CATACTTTGA CTTCTTCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe36796 | |
Clone ID Related Accession (Same CDS sequence) | XM_014114126.1 , XM_014114126.2 | |
Accession Version | XM_014114126.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | beta-glucuronidase isoform X3 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726061.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCCAG GACCCGGGCA CGAGAGTGGT GCTGAGGATT GGCAGCGCCC ACTACTATGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013969601.1 |
CDS | 1..1302 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014114126.1 |
1 | ATGGAGCCAG GACCCGGGCA CGAGAGTGGT GCTGAGGATT GGCAGCGCCC ACTACTATGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe36796 | |
Clone ID Related Accession (Same CDS sequence) | XM_014114126.1 , XM_014114126.2 | |
Accession Version | XM_014114126.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | beta-glucuronidase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006588.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_014114126.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGCCAG GACCCGGGCA CGAGAGTGGT GCTGAGGATT GGCAGCGCCC ACTACTATGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013969601.1 |
CDS | 1..1302 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014114126.2 |
1 | ATGGAGCCAG GACCCGGGCA CGAGAGTGGT GCTGAGGATT GGCAGCGCCC ACTACTATGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A novel GUSB mutation in Brazilian terriers with severe skeletal abnormalities defines the disease as mucopolysaccharidosis VII. |
Construction and characterization of an eightfold redundant dog genomic bacterial artificial chromosome library. |
Cloning of the canine beta-glucuronidase cDNA, mutation identification in canine MPS VII, and retroviral vector-mediated correction of MPS VII cells. |