Gene Symbol | DIO1 |
Entrez Gene ID | 403635 |
Full Name | iodothyronine deiodinase 1 |
Synonyms | ITDI1,TXDI1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » DIO1 cDNA ORF clone
Gene Symbol | DIO1 |
Entrez Gene ID | 403635 |
Full Name | iodothyronine deiodinase 1 |
Synonyms | ITDI1,TXDI1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001007126.2 | NP_001007127.1 | type I iodothyronine deiodinase |
Bos taurus (cattle) | DIO1 | NP_001116065.1 |
Rattus norvegicus (Norway rat) | Dio1 | NP_067685.5 |
Gallus gallus (chicken) | DIO1 | NP_001091083.1 |
Danio rerio (zebrafish) | dio1 | NP_001007284.2 |
Xenopus tropicalis (tropical clawed frog) | dio1 | NP_001243226.1 |
Homo sapiens (human) | DIO1 | NP_000783.2 |
Canis lupus familiaris (dog) | DIO1 | NP_001007127.1 |
DIO1 | NP_001116124.1 | |
Mus musculus (house mouse) | Dio1 | NP_031886.3 |
Pan troglodytes (chimpanzee) | DIO1 | NP_001116123.1 |
Identification of critical amino acids for 3,5,3'-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes.
Toyoda N, Harney JW, Berry MJ, Larsen PR
The Journal of biological chemistry269(32)20329-34(1994 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following DIO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DIO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00294 | |
Clone ID Related Accession (Same CDS sequence) | NM_001007126.2 | |
Accession Version | NM_001007126.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Canis lupus familiaris(dog) | |
Product | type I iodothyronine deiodinase | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U11762.1, AAEX03003823.1 and DN336574.1. On May 23, 2007 this sequence version replaced NM_001007126.1. ##Evidence-Data-START## Transcript exon combination :: U11762.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547742, SAMN00013514 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGGCTGC CCCGGCCAGT GCTGTGGCTA AGGAGGCTCT GGGTCCTCTT GCAGGTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001007127.1 |
CDS | 32..766 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001007126.2 |
1 | ATGGGGCTGC CCCGGCCAGT GCTGTGGCTA AGGAGGCTCT GGGTCCTCTT GCAGGTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Identification of critical amino acids for 3,5,3'-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes. |