Gene Symbol | ABCC1 |
Entrez Gene ID | 403453 |
Full Name | ATP binding cassette subfamily C member 1 |
Synonyms | MRP1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » ABCC1 cDNA ORF clone
Gene Symbol | ABCC1 |
Entrez Gene ID | 403453 |
Full Name | ATP binding cassette subfamily C member 1 |
Synonyms | MRP1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001002971.1 | NP_001002971.1 | multidrug resistance-associated protein 1 |
Danio rerio (zebrafish) | abcc1 | XP_001341895.3 |
Caenorhabditis elegans (roundworm) | mrp-1 | NP_001033553.1 |
Arabidopsis thaliana (thale cress) | MRP5 | NP_171908.1 |
Oryza sativa (rice) | Os03g0142800 | NP_001048934.1 |
Canis lupus familiaris (dog) | ABCC1 | NP_001002971.1 |
Bos taurus (cattle) | ABCC1 | NP_776648.1 |
Homo sapiens (human) | ABCC1 | NP_004987.2 |
Pan troglodytes (chimpanzee) | ABCC1 | XP_001145351.1 |
Rattus norvegicus (Norway rat) | Abcc1 | NP_071617.2 |
Gallus gallus (chicken) | ABCC1 | NP_001012540.1 |
Mus musculus (house mouse) | Abcc1 | NP_032602.1 |
Caenorhabditis elegans (roundworm) | mrp-2 | NP_508121.1 |
Externalization of phosphatidylserine via multidrug resistance 1 (MDR1)/P-glycoprotein in oxalate-treated renal epithelial cells: implications for calcium oxalate urolithiasis.
Li YH, Yu SL, Gan XG, Pan SH, Teng YQ, An RH
International urology and nephrology48(2)175-81(2016 Feb)
Expression and role of PGP, BCRP, MRP1 and MRP3 in multidrug resistance of canine mammary cancer cells.
Paw?owski KM, Mucha J, Majchrzak K, Motyl T, Kr?l M
BMC veterinary research9119(2013 Jun)
ABC transporters in the eyes of dogs and implications in drug therapy.
Haritova AM, Krastev SZ, Santos RR, Schrickx JA, Fink-Gremmels J
Current eye research38(2)271-7(2013 Feb)
Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.
Westlake CJ, Payen L, Gao M, Cole SP, Deeley RG
The Journal of biological chemistry279(51)53571-83(2004 Dec)
Identification and characterization of the canine multidrug resistance-associated protein.
Ma L, Pratt SE, Cao J, Dantzig AH, Moore RE, Slapak CA
Molecular cancer therapeutics1(14)1335-42(2002 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
oxalate increases the synthesis of MDR1 P-gp, which plays a key role in hyperoxaluria-promoted calcium oxalate urolithiasis by facilitating phosphatidylserine redistribution in renal epithelial cells.
Title: Externalization of phosphatidylserine via multidrug resistance 1 (MDR1)/P-glycoprotein in oxalate-treated renal epithelial cells: implications for calcium oxalate urolithiasis.
expression and role in multidrug resistance of mammary cancer cells
Title: Expression and role of PGP, BCRP, MRP1 and MRP3 in multidrug resistance of canine mammary cancer cells.
ABCC1, ABCC3 and ABCC4 are expressed predominantly in the conjunctiva and at very low levels in the cornea.
Title: ABC transporters in the eyes of dogs and implications in drug therapy.
the multidrug resistance protein 1 COOH-terminal region has elements with five conserved hydrophobic amino acids that are required for activity
Title: Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.
The following ABCC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00060 | |
Clone ID Related Accession (Same CDS sequence) | NM_001002971.1 | |
Accession Version | NM_001002971.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4596bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Canis lupus familiaris(dog) | |
Product | multidrug resistance-associated protein 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY363728.1. ##Evidence-Data-START## Transcript exon combination :: AY363728.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCGCTCC GCGGCTTCTG CAGCGCCGAC GGCTCCGACC CCTTCTGGGA GTGGGATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001002971.1 |
CDS | 9..4604 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001002971.1 |
1 | ATGGCGCTCC GCGGCTTCTG CAGCGCCGAC GGCTCCGACC CCTTCTGGGA GTGGGATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Externalization of phosphatidylserine via multidrug resistance 1 (MDR1)/P-glycoprotein in oxalate-treated renal epithelial cells: implications for calcium oxalate urolithiasis. |
Expression and role of PGP, BCRP, MRP1 and MRP3 in multidrug resistance of canine mammary cancer cells. |
ABC transporters in the eyes of dogs and implications in drug therapy. |
Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region. |
Identification and characterization of the canine multidrug resistance-associated protein. |