Gene Symbol | GLUL |
Entrez Gene ID | 403443 |
Full Name | glutamate-ammonia ligase |
Synonyms | GS |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » GLUL cDNA ORF clone
Gene Symbol | GLUL |
Entrez Gene ID | 403443 |
Full Name | glutamate-ammonia ligase |
Synonyms | GS |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001293224.1 | NP_001280153.1 | glutamine synthetase isoform 2 |
NM_001002965.2 | NP_001002965.2 | glutamine synthetase isoform 1 |
Bos taurus (cattle) | GLUL | NP_001035564.1 |
Mus musculus (house mouse) | Glul | NP_032157.2 |
Rattus norvegicus (Norway rat) | Glul | NP_058769.4 |
Danio rerio (zebrafish) | glulb | NP_878286.2 |
Drosophila melanogaster (fruit fly) | Gs1 | NP_001162839.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008988 | XP_319738.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_06888 | XP_003709618.1 |
Pan troglodytes (chimpanzee) | GLUL | XP_001160939.1 |
Schizosaccharomyces pombe (fission yeast) | gln1 | NP_593400.1 |
Neurospora crassa | NCU06724 | XP_960904.2 |
Arabidopsis thaliana (thale cress) | GSR 1 | NP_198576.1 |
Arabidopsis thaliana (thale cress) | GSR2 | NP_176794.1 |
Oryza sativa (rice) | Os03g0223400 | NP_001049424.1 |
Xenopus tropicalis (tropical clawed frog) | glul | XP_002944531.2 |
Gallus gallus (chicken) | GLUL | NP_990824.1 |
GLUL | XP_001114827.1 | |
Canis lupus familiaris (dog) | GLUL | NP_001002965.1 |
Caenorhabditis elegans (roundworm) | gln-1 | NP_509012.2 |
Saccharomyces cerevisiae (baker's yeast) | GLN1 | NP_015360.2 |
Kluyveromyces lactis | KLLA0E06293g | XP_454231.1 |
Arabidopsis thaliana (thale cress) | GLN1;4 | NP_568335.1 |
Homo sapiens (human) | GLUL | NP_002056.2 |
Eremothecium gossypii | AGOS_ACR182C | NP_983584.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_14279 | XP_003719336.1 |
Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
Krajewski WW, Collins R, Holmberg-Schiavone L, Jones TA, Karlberg T, Mowbray SL
Journal of molecular biology375(1)217-28(2008 Jan)
A splice variant acquiring an extra transcript leader region decreases the translation of glutamine synthetase gene.
Shin D, Park S, Park C
The Biochemical journal374(Pt 1)175-84(2003 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Crystal structure of GLUL illustrates substrate-induced conformational change and provides opportunities for drug and herbicide design.
Title: Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
The following GLUL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GLUL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00430 | |
Clone ID Related Accession (Same CDS sequence) | NM_001293224.1 | |
Accession Version | NM_001293224.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Canis lupus familiaris(dog) | |
Product | glutamine synthetase isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF544242.1, DN425737.1, BM537412.1, DN875727.1 and AAEX03005140.1. On Jun 7, 2014 this sequence version replaced XM_005622220.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: AF544242.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCACCT CTGCGAGTTC CCACTTGAAC AAAGGCATCA AGCAGGTGTA CATGTCCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001280153.1 |
CDS | 124..1245 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001293224.1 |
1 | ATGGCCACCT CTGCGAGTTC CCACTTGAAC AAAGGCATCA AGCAGGTGTA CATGTCCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe00433 | |
Clone ID Related Accession (Same CDS sequence) | NM_001002965.2 | |
Accession Version | NM_001002965.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-11-17 | |
Organism | Canis lupus familiaris(dog) | |
Product | glutamine synthetase isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF544242.1, DN428718.1, BM537412.1, DN875727.1 and AAEX03005140.1. On or before Jun 7, 2014 this sequence version replaced XM_005622219.1, NM_001002965.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AF544242.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGACCAGC GGGAGCCCGA GAGCCTGGAG AGGCGCGAAC GCGACTCCAA ACGGAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001002965.2 |
CDS | 124..1365 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001002965.2 |
1 | ATGGACCAGC GGGAGCCCGA GAGCCTGGAG AGGCGCGAAC GCGACTCCAA ACGGAGAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design. |
A splice variant acquiring an extra transcript leader region decreases the translation of glutamine synthetase gene. |