Gene Symbol | MAPK3 |
Entrez Gene ID | 100855877 |
Full Name | mitogen-activated protein kinase 3 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » MAPK3 cDNA ORF clone
Gene Symbol | MAPK3 |
Entrez Gene ID | 100855877 |
Full Name | mitogen-activated protein kinase 3 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001252035.1 | NP_001238964.1 | mitogen-activated protein kinase 3 |
Arabidopsis thaliana (thale cress) | MPK12 | NP_182131.2 |
Oryza sativa (rice) | Os08g0157000 | NP_001061028.2 |
Canis lupus familiaris (dog) | MAPK3 | XP_005621414.1 |
Sodium-calcium exchanger 1 regulates epithelial cell migration via calcium-dependent extracellular signal-regulated kinase signaling.
Balasubramaniam SL, Gopalakrishnapillai A, Gangadharan V, Duncan RL, Barwe SP
The Journal of biological chemistry290(20)12463-73(2015 May)
High glucose concentration stimulates NHE-1 activity in distal nephron cells: the role of the Mek/Erk1/2/p90RSK and p38MAPK signaling pathways.
da Costa-Pessoa JM, Damasceno RS, Machado UF, Beloto-Silva O, Oliveira-Souza M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology33(2)333-43(2014)
Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells.
Lall MM, Harned J, McGahan MC
Molecular vision192106-12(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
inhibition of NCX1 by KB-R7943 in Madin-Darby canine kidney cells, LLC-PK1, and human primary renal epithelial cells (HREpiC) increased ERK1/2 activation and cell migration.
Title: Sodium-calcium exchanger 1 regulates epithelial cell migration via calcium-dependent extracellular signal-regulated kinase signaling.
These results suggested that extracellular high glucose stimulated NHE-1 acutely and chronically through Mek/Erk1/2/p90(RSK) and p38MAPK pathways, respectively.
Title: High glucose concentration stimulates NHE-1 activity in distal nephron cells: the role of the Mek/Erk1/2/p90RSK and p38MAPK signaling pathways.
This is the first study to demonstrate that hydrogen peroxide and an inhibitor of ERK1/2 activation can increase the levels of the iron storage protein, ferritin.
Title: Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells.
The following MAPK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAPK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00497 | |
Clone ID Related Accession (Same CDS sequence) | NM_001252035.1 | |
Accession Version | NM_001252035.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-22 | |
Organism | Canis lupus familiaris(dog) | |
Product | mitogen-activated protein kinase 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN396855.1 and AAEX03004405.1. On Oct 30, 2011 this sequence version replaced XM_536917.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single sequence was available for the full length of the gene. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2240594 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGGCGGGG AGCCCCGGGG AGCCGATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001238964.1 |
CDS | 15..1157 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001252035.1 |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGGCGGGG AGCCCCGGGG AGCCGATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sodium-calcium exchanger 1 regulates epithelial cell migration via calcium-dependent extracellular signal-regulated kinase signaling. |
High glucose concentration stimulates NHE-1 activity in distal nephron cells: the role of the Mek/Erk1/2/p90RSK and p38MAPK signaling pathways. |
Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells. |