ORF » Species Summary » Homo sapiens » Reactome » Toll Like Receptor 4 (TLR4) Cascade

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  • Entrez Gene ID (e.g. 7157)
  • gene symbol (e.g. TP53)
  • gene name (e.g. tumor protein p53)
  • gene synonyms (e.g. FLJ92943)
  • Ensembl ID (e.g. ENSG0000141510)
  • Accession No. (e.g. NM_000546)
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Homo sapiens (human) Toll Like Receptor 4 (TLR4) Cascade (provided by Reactome)

Browse by Letter Index, Genomic Locus

126 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.


Gene Symbol Full Name
S100B S100 calcium binding protein B
TLR6 toll like receptor 6
MAPK14 mitogen-activated protein kinase 14
UBE2D2 ubiquitin conjugating enzyme E2 D2
RPS6KA5 ribosomal protein S6 kinase A5
PPP2CB protein phosphatase 2 catalytic subunit beta
MAP2K6 mitogen-activated protein kinase kinase 6
RIPK1 receptor interacting serine/threonine kinase 1
CD36 CD36 molecule
CREB1 cAMP responsive element binding protein 1
ITGAM integrin subunit alpha M
CHUK conserved helix-loop-helix ubiquitous kinase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
APP amyloid beta precursor protein
UBE2D3 ubiquitin conjugating enzyme E2 D3
SAA1 serum amyloid A1
UBE2N ubiquitin conjugating enzyme E2 N
LY86 lymphocyte antigen 86
LY96 lymphocyte antigen 96
MAP3K1 mitogen-activated protein kinase kinase kinase 1
MAP2K1 mitogen-activated protein kinase kinase 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
RELA RELA proto-oncogene, NF-kB subunit
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon
UBE2D1 ubiquitin conjugating enzyme E2 D1
DUSP3 dual specificity phosphatase 3
NOD2 nucleotide binding oligomerization domain containing 2
MEF2A myocyte enhancer factor 2A
NOD1 nucleotide binding oligomerization domain containing 1
JUN Jun proto-oncogene, AP-1 transcription factor subunit
DHX9 DExH-box helicase 9
UBC ubiquitin C
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
MAPK11 mitogen-activated protein kinase 11
PLCG2 phospholipase C gamma 2
MAP2K3 mitogen-activated protein kinase kinase 3
TLR3 toll like receptor 3
IRAK1 interleukin 1 receptor associated kinase 1
MAPK1 mitogen-activated protein kinase 1
CASP8 caspase 8
TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1
IRAK3 interleukin 1 receptor associated kinase 3
TANK TRAF family member associated NFKB activator
ELK1 ELK1, ETS transcription factor
PPP2CA protein phosphatase 2 catalytic subunit alpha
ATF1 activating transcription factor 1
TLR4 toll like receptor 4
BIRC3 baculoviral IAP repeat containing 3
RPS6KA1 ribosomal protein S6 kinase A1
DNM2 dynamin 2
SKP1 S-phase kinase associated protein 1
ECSIT ECSIT signalling integrator
SOCS1 suppressor of cytokine signaling 1
TRAF3 TNF receptor associated factor 3
PELI1 pellino E3 ubiquitin protein ligase 1
LBP lipopolysaccharide binding protein
RPS27A ribosomal protein S27a
MEF2C myocyte enhancer factor 2C
TICAM1 toll like receptor adaptor molecule 1
TRAF6 TNF receptor associated factor 6
MAP2K7 mitogen-activated protein kinase kinase 7
FOS Fos proto-oncogene, AP-1 transcription factor subunit
SARM1 sterile alpha and TIR motif containing 1
UBE2V1 ubiquitin conjugating enzyme E2 V1
BTK Bruton tyrosine kinase
NFKB2 nuclear factor kappa B subunit 2
RPS6KA3 ribosomal protein S6 kinase A3
DUSP7 dual specificity phosphatase 7
TAB3 TGF-beta activated kinase 1 and MAP3K7 binding protein 3
ATF2 activating transcription factor 2
MAPK10 mitogen-activated protein kinase 10
RIPK3 receptor interacting serine/threonine kinase 3
MAPK8 mitogen-activated protein kinase 8
TICAM2 toll like receptor adaptor molecule 2
TLR2 toll like receptor 2
IRF3 interferon regulatory factor 3
SIGIRR single Ig and TIR domain containing
MIR718 microRNA 718
MIR6502 microRNA 6502
ITGB2 integrin subunit beta 2
VRK3 vaccinia related kinase 3
IRF7 interferon regulatory factor 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BPI bactericidal/permeability-increasing protein
PELI3 pellino E3 ubiquitin protein ligase family member 3
DNM1 dynamin 1
PPP2R1B protein phosphatase 2 scaffold subunit Abeta
UBB ubiquitin B
RPS6KA2 ribosomal protein S6 kinase A2
TIRAP TIR domain containing adaptor protein
NFKB1 nuclear factor kappa B subunit 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
MAP2K4 mitogen-activated protein kinase kinase 4
IRAK4 interleukin 1 receptor associated kinase 4
DNM3 dynamin 3
PPP2R1A protein phosphatase 2 scaffold subunit Aalpha
DUSP6 dual specificity phosphatase 6
NFKBIA NFKB inhibitor alpha
TNIP2 TNFAIP3 interacting protein 2
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
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