CREB1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CREB1
Entrez Gene ID	395099
Full Name	cAMP responsive element binding protein 1
General protein information	Preferred Names cAMP responsive element binding protein 1 Names cyclic AMP-responsive element-binding protein 1 cAMP response element-binding protein
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
XM_015289371.1	XP_015144857.1	cyclic AMP-responsive element-binding protein 1 isoform X1
XM_015289372.1	XP_015144858.1	cyclic AMP-responsive element-binding protein 1 isoform X2
XM_015289373.1	XP_015144859.1	cyclic AMP-responsive element-binding protein 1 isoform X3
XM_015289373.2	XP_015144859.1	cyclic AMP-responsive element-binding protein 1 isoform X3
NM_204450.2	NP_989781.1	cyclic AMP-responsive element-binding protein 1
XM_015289371.2	XP_015144857.1	cyclic AMP-responsive element-binding protein 1 isoform X1
XM_015289372.2	XP_015144858.1	cyclic AMP-responsive element-binding protein 1 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	CREB1	NP_604391.1
Canis lupus familiaris (dog)	CREB1	XP_860219.2
	CREB1	XP_001107192.1
Bos taurus (cattle)	CREB1	NP_776710.1
Rattus norvegicus (Norway rat)	Creb1	NP_112279.1
Pan troglodytes (chimpanzee)	CREB1	XP_516051.2
Mus musculus (house mouse)	Creb1	NP_034082.1
Gallus gallus (chicken)	CREB1	NP_989781.1
Danio rerio (zebrafish)	creb1a	NP_957203.1
Xenopus tropicalis (tropical clawed frog)	creb1	NP_998851.1

Gene Ontology
Bibliography

Related articles in PubMed

Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.
Shanmughapriya S, Rajan S, Hoffman NE, Zhang X, Guo S, Kolesar JE, Hines KJ, Ragheb J, Jog NR, Caricchio R, Baba Y, Zhou Y, Kaufman BA, Cheung JY, Kurosaki T, Gill DL, Madesh M
Science signaling8(366)ra23(2015 Mar)

The nitric oxide-cGKII system relays death and survival signals during embryonic retinal development via AKT-induced CREB1 activation.
Socodato R, Brito R, Portugal CC, de Oliveira NA, Calaza KC, Paes-de-Carvalho R
Cell death and differentiation21(6)915-28(2014 Jun)

Breed-dependent transcriptional regulation of phosphoenolpyruvate carboxylase, cytosolic form, expression in the liver of broiler chickens.
Guo F, Zhang Y, Su L, Ahmed AA, Ni Y, Zhao R
Poultry science92(10)2737-44(2013 Oct)

Prenatal auditory stimulation alters the levels of CREB mRNA, p-CREB and BDNF expression in chick hippocampus.
Chaudhury S, Wadhwa S
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience27(6)583-90(2009 Oct)

Glutamate accelerates RPE cell proliferation through ERK1/2 activation via distinct receptor-specific mechanisms.
Garc?a S, L?pez E, L?pez-Colom? AM
Journal of cellular biochemistry104(2)377-90(2008 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results showed that a transcriptional regulatory circuit involving Ca2+ -dependent activation of CREB controls the Ca2+ uptake capability of mitochondria and hence regulates mitochondrial metabolism.
Title: Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.

These data demonstrate that NO-mediated cGKII signaling may function to control the viability of neuronal cells during early retinal development via AKT/CREB1 activity.
Title: The nitric oxide-cGKII system relays death and survival signals during embryonic retinal development via AKT-induced CREB1 activation.

A fast-growing chicken breed had significantly higher hepatic mRNA expression levels of the cytosolic form of PEPCK and significantly higher hepatic mRNA and protein expression levels of cAMP response element binding protein 1.
Title: Breed-dependent transcriptional regulation of phosphoenolpyruvate carboxylase, cytosolic form, expression in the liver of broiler chickens.

Enhanced phosphorylation of CREB during development following prenatal sound stimulation may be responsible for cell survival. Increased levels of p-CREB again at PH1 may trigger synthesis of proteins necessary for synaptic plasticity.
Title: Prenatal auditory stimulation alters the levels of CREB mRNA, p-CREB and BDNF expression in chick hippocampus.

molecular mechanisms leading to glutamate-induced proliferation by determining ERK1/2 and CREB phoshporylation in chick RPE cells in primary culture and the human-derived RPE cell line ARPE-19
Title: Glutamate accelerates RPE cell proliferation through ERK1/2 activation via distinct receptor-specific mechanisms.

The following CREB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CREB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OGa00758	NM_204450.2 Latest version!	Gallus gallus cAMP responsive element binding protein 1 (CREB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OGa00758	XM_015289371.2 Latest version!	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OGa38296	XM_015289372.2 Latest version!	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
OGa38297	XM_015289373.2 Latest version!	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
View Old Accession Versions >>
OGa38297	XM_015289373.1	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
OGa00758	XM_015289371.1	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OGa38296	XM_015289372.1	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CREB1 ( NM_204450.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989781.1 Gallus gallus cAMP responsive element binding protein 1 (CREB1), mRNA.

Price & Availability↑

CloneID	OGa00758
Clone ID Related Accession (Same CDS sequence)	XM_015289371.1 , NM_204450.2 , XM_015289371.2
Accession Version	NM_204450.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	cyclic AMP-responsive element-binding protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ851654.1. On Feb 27, 2005 this sequence version replaced NM_204450.1. ##Evidence-Data-START## Transcript exon combination :: AJ851654.1, BX950641.1 [ECO:0000332] ##Evidence-Data-END##

ATGACCATGG AATCTGGAGC AGAGAACCAG CAGAGTGGAG ATGCAGCCGT TACAGAGGCA 
GAAACCCAAC AGATGACAGT ACAGGCACAA CCACAGATTG CAACGTTAGC CCAGGTATCT 
ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989781.1
CDS	218..1201
Translation	MTMESGAENQQSGDAAVTEAETQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETAAPAIATVTVPTPIYQTSSGQYIAITQGGAIQLSNNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	NM_204450.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cAMP responsive element binding protein 1 (CREB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204450.2

ORF Insert Sequence:

ATGACCATGG AATCTGGAGC AGAGAACCAG CAGAGTGGAG ATGCAGCCGT TACAGAGGCA 
GAAACCCAAC AGATGACAGT ACAGGCACAA CCACAGATTG CAACGTTAGC CCAGGTATCT 
ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CREB1 ( XM_015289371.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015144857.1 Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa00758
Clone ID Related Accession (Same CDS sequence)	XM_015289371.1 , NM_204450.2 , XM_015289371.2
Accession Version	XM_015289371.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-03
Organism	Gallus gallus(chicken)
Product	cyclic AMP-responsive element-binding protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_455902.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCATGG AATCTGGAGC AGAGAACCAG CAGAGTGGAG ATGCAGCCGT TACAGAGGCA 
GAAACCCAAC AGATGACAGT ACAGGCACAA CCACAGATTG CAACGTTAGC CCAGGTATCT 
ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015144857.1
CDS	475..1458
Translation	MTMESGAENQQSGDAAVTEAETQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETAAPAIATVTVPTPIYQTSSGQYIAITQGGAIQLSNNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	XM_015289371.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015289371.1

ORF Insert Sequence:

ATGACCATGG AATCTGGAGC AGAGAACCAG CAGAGTGGAG ATGCAGCCGT TACAGAGGCA 
GAAACCCAAC AGATGACAGT ACAGGCACAA CCACAGATTG CAACGTTAGC CCAGGTATCT 
ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CREB1 ( XM_015289371.2 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015144857.1 Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa00758
Clone ID Related Accession (Same CDS sequence)	XM_015289371.1 , NM_204450.2 , XM_015289371.2
Accession Version	XM_015289371.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-16
Organism	Gallus gallus(chicken)
Product	cyclic AMP-responsive element-binding protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006094.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015289371.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCATGG AATCTGGAGC AGAGAACCAG CAGAGTGGAG ATGCAGCCGT TACAGAGGCA 
GAAACCCAAC AGATGACAGT ACAGGCACAA CCACAGATTG CAACGTTAGC CCAGGTATCT 
ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015144857.1
CDS	309..1292
Translation	MTMESGAENQQSGDAAVTEAETQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETAAPAIATVTVPTPIYQTSSGQYIAITQGGAIQLSNNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	XM_015289371.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015289371.2

ORF Insert Sequence:

ATGACCATGG AATCTGGAGC AGAGAACCAG CAGAGTGGAG ATGCAGCCGT TACAGAGGCA 
GAAACCCAAC AGATGACAGT ACAGGCACAA CCACAGATTG CAACGTTAGC CCAGGTATCT 
ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CREB1 ( XM_015289372.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015144858.1 Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OGa38296
Clone ID Related Accession (Same CDS sequence)	XM_015289372.1 , XM_015289372.2
Accession Version	XM_015289372.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-03
Organism	Gallus gallus(chicken)
Product	cyclic AMP-responsive element-binding protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_455902.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015144858.1
CDS	336..1199
Translation	MPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETAAPAIATVTVPTPIYQTSSGQYIAITQGGAIQLSNNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	XM_015289372.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015289372.1

ORF Insert Sequence:

ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CREB1 ( XM_015289372.2 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015144858.1 Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OGa38296
Clone ID Related Accession (Same CDS sequence)	XM_015289372.1 , XM_015289372.2
Accession Version	XM_015289372.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-16
Organism	Gallus gallus(chicken)
Product	cyclic AMP-responsive element-binding protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006094.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015289372.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015144858.1
CDS	166..1029
Translation	MPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETAAPAIATVTVPTPIYQTSSGQYIAITQGGAIQLSNNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	XM_015289372.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015289372.2

ORF Insert Sequence:

ATGCCAGCAG CTCACGCCAC GTCTTCTGCA CCCACGGTGA CCTTAGTTCA GCTGCCCAAT 
GGGCAGACAG TTCAAGTGCA CGGCGTAATT CAGGCTGCCC AGCCATCAGT TATTCAGTCT 
CCACAGGTCC AGACAGTTCA GATTTCAACT ATAGCAGAAA GTGAAGACTC ACAGGAATCA 
GTGGACAGTG TCACAGATTC ACAGAAACGG AGAGAAATTC TTTCCAGACG ACCCTCCTAC 
AGAAAAATTT TGAATGACTT GTCCTCAGAC GCCCCAGGAG TGCCAAGGAT CGAAGAGGAA 
AAGTCTGAAG AGGAAACAGC AGCACCTGCC ATTGCCACTG TTACGGTGCC AACTCCCATT 
TACCAAACCA GCAGTGGGCA GTACATTGCT ATTACGCAAG GAGGAGCAAT TCAGTTGTCT 
AACAACGGCA CGGATGGAGT ACAAGGTCTC CAGACGTTGA CTATGACCAA TGCAGCTGCA 
ACACAACCTG GCACTACCAT TTTACAATAT GCACAGACCA CAGATGGACA ACAGATACTT 
GTACCCAGCA ACCAAGTTGT AGTACAAGCT GCCTCAGGAG ATGTACAGAC CTACCAGATT 
CGCACCGCCC CTACCAGCAC CATTGCACCT GGAGTAGTCA TGGCATCATC TCCAGCACTT 
CCAACCCAGC CAGCAGAAGA GGCCGCACGG AAGAGAGAAG TGCGTCTAAT GAAGAACAGA 
GAGGCAGCAC GTGAATGTCG CAGGAAGAAA AAGGAGTATG TGAAATGTCT AGAAAATCGA 
GTGGCTGTGC TTGAAAACCA AAACAAGACA CTGATTGAGG AGTTGAAAGC ACTTAAAGAC 
CTTTACTGCC ACAAATCAGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CREB1 ( XM_015289373.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015144859.1 Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OGa38297
Clone ID Related Accession (Same CDS sequence)	XM_015289373.1 , XM_015289373.2
Accession Version	XM_015289373.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-03
Organism	Gallus gallus(chicken)
Product	cyclic AMP-responsive element-binding protein 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_455902.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCAATG CAGCTGCAAC ACAACCTGGC ACTACCATTT TACAATATGC ACAGACCACA 
GATGGACAAC AGATACTTGT ACCCAGCAAC CAAGTTGTAG TACAAGCTGC CTCAGGAGAT 
GTACAGACCT ACCAGATTCG CACCGCCCCT ACCAGCACCA TTGCACCTGG AGTAGTCATG 
GCATCATCTC CAGCACTTCC AACCCAGCCA GCAGAAGAGG CCGCACGGAA GAGAGAAGTG 
CGTCTAATGA AGAACAGAGA GGCAGCACGT GAATGTCGCA GGAAGAAAAA GGAGTATGTG 
AAATGTCTAG AAAATCGAGT GGCTGTGCTT GAAAACCAAA ACAAGACACT GATTGAGGAG 
TTGAAAGCAC TTAAAGACCT TTACTGCCAC AAATCAGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015144859.1
CDS	633..1034
Translation	MTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	XM_015289373.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015289373.1

ORF Insert Sequence:

ATGACCAATG CAGCTGCAAC ACAACCTGGC ACTACCATTT TACAATATGC ACAGACCACA 
GATGGACAAC AGATACTTGT ACCCAGCAAC CAAGTTGTAG TACAAGCTGC CTCAGGAGAT 
GTACAGACCT ACCAGATTCG CACCGCCCCT ACCAGCACCA TTGCACCTGG AGTAGTCATG 
GCATCATCTC CAGCACTTCC AACCCAGCCA GCAGAAGAGG CCGCACGGAA GAGAGAAGTG 
CGTCTAATGA AGAACAGAGA GGCAGCACGT GAATGTCGCA GGAAGAAAAA GGAGTATGTG 
AAATGTCTAG AAAATCGAGT GGCTGTGCTT GAAAACCAAA ACAAGACACT GATTGAGGAG 
TTGAAAGCAC TTAAAGACCT TTACTGCCAC AAATCAGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CREB1 ( XM_015289373.2 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015144859.1 Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OGa38297
Clone ID Related Accession (Same CDS sequence)	XM_015289373.1 , XM_015289373.2
Accession Version	XM_015289373.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-16
Organism	Gallus gallus(chicken)
Product	cyclic AMP-responsive element-binding protein 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006094.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015289373.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCAATG CAGCTGCAAC ACAACCTGGC ACTACCATTT TACAATATGC ACAGACCACA 
GATGGACAAC AGATACTTGT ACCCAGCAAC CAAGTTGTAG TACAAGCTGC CTCAGGAGAT 
GTACAGACCT ACCAGATTCG CACCGCCCCT ACCAGCACCA TTGCACCTGG AGTAGTCATG 
GCATCATCTC CAGCACTTCC AACCCAGCCA GCAGAAGAGG CCGCACGGAA GAGAGAAGTG 
CGTCTAATGA AGAACAGAGA GGCAGCACGT GAATGTCGCA GGAAGAAAAA GGAGTATGTG 
AAATGTCTAG AAAATCGAGT GGCTGTGCTT GAAAACCAAA ACAAGACACT GATTGAGGAG 
TTGAAAGCAC TTAAAGACCT TTACTGCCAC AAATCAGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015144859.1
CDS	504..905
Translation	MTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	XM_015289373.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cAMP responsive element binding protein 1 (CREB1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015289373.2

ORF Insert Sequence:

ATGACCAATG CAGCTGCAAC ACAACCTGGC ACTACCATTT TACAATATGC ACAGACCACA 
GATGGACAAC AGATACTTGT ACCCAGCAAC CAAGTTGTAG TACAAGCTGC CTCAGGAGAT 
GTACAGACCT ACCAGATTCG CACCGCCCCT ACCAGCACCA TTGCACCTGG AGTAGTCATG 
GCATCATCTC CAGCACTTCC AACCCAGCCA GCAGAAGAGG CCGCACGGAA GAGAGAAGTG 
CGTCTAATGA AGAACAGAGA GGCAGCACGT GAATGTCGCA GGAAGAAAAA GGAGTATGTG 
AAATGTCTAG AAAATCGAGT GGCTGTGCTT GAAAACCAAA ACAAGACACT GATTGAGGAG 
TTGAAAGCAC TTAAAGACCT TTACTGCCAC AAATCAGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.
Science signaling8(366)ra23(2015 Mar)
Shanmughapriya S,Rajan S,Hoffman NE,Zhang X,Guo S,Kolesar JE,Hines KJ,Ragheb J,Jog NR,Caricchio R,Baba Y,Zhou Y,Kaufman BA,Cheung JY,Kurosaki T,Gill DL,Madesh M

The nitric oxide-cGKII system relays death and survival signals during embryonic retinal development via AKT-induced CREB1 activation.
Cell death and differentiation21(6)915-28(2014 Jun)
Socodato R,Brito R,Portugal CC,de Oliveira NA,Calaza KC,Paes-de-Carvalho R

Breed-dependent transcriptional regulation of phosphoenolpyruvate carboxylase, cytosolic form, expression in the liver of broiler chickens.
Poultry science92(10)2737-44(2013 Oct)
Guo F,Zhang Y,Su L,Ahmed AA,Ni Y,Zhao R

Prenatal auditory stimulation alters the levels of CREB mRNA, p-CREB and BDNF expression in chick hippocampus.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience27(6)583-90(2009 Oct)
Chaudhury S,Wadhwa S

Glutamate accelerates RPE cell proliferation through ERK1/2 activation via distinct receptor-specific mechanisms.
Journal of cellular biochemistry104(2)377-90(2008 May)
Garc?a S,L?pez E,L?pez-Colom? AM

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CREB1 cDNA ORF clone, Gallus gallus(chicken)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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