sox11b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	sox11b
Entrez Gene ID	30603
Full Name	SRY (sex determining region Y)-box 11b
Synonyms	fc90d10,wu:fb53e02,wu:fc90d10
General protein information	Preferred Names SRY (sex determining region Y)-box 11b Names SRY (sex determining region Y)-box 11b SRY-box containing gene 11b etID55462.20
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131337.1	NP_571412.1	SRY-box transcription factor 11b

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Histological and transcriptomic effects of 17?-methyltestosterone on zebrafish gonad development.
Lee SLJ, Horsfield JA, Black MA, Rutherford K, Fisher A, Gemmell NJ
BMC genomics18(1)557(2017 Jul)

Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration.
Mu Z, Zhang S, He C, Hou H, Liu D, Hu N, Xu H
Neuroscience bulletin33(1)53-61(2017 Feb)

The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation.
Wang Y, Lu Y, Zhang Y, Ning Z, Li Y, Zhao Q, Lu H, Huang R, Xia X, Feng Q, Liang X, Liu K, Zhang L, Lu T, Huang T, Fan D, Weng Q, Zhu C, Lu Y, Li W, Wen Z, Zhou C, Tian Q, Kang X, Shi M, Zhang W, Jang S, Du F, He S, Liao L, Li Y, Gui B, He H, Ning Z, Yang C, He L, Luo L, Yang R, Luo Q, Liu X, Li S, Huang W, Xiao L, Lin H, Han B, Zhu Z
Nature genetics47(6)625-31(2015 Jun)

Sox4 regulates choroid fissure closure by limiting Hedgehog signaling during ocular morphogenesis.
Wen W, Pillai-Kastoori L, Wilson SG, Morris AC
Developmental biology399(1)139-53(2015 Mar)

Sequencing and De Novo Assembly of the Gonadal Transcriptome of the Endangered Chinese Sturgeon (Acipenser sinensis).
Yue H, Li C, Du H, Zhang S, Wei Q
PloS one10(6)e0127332(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that SOX11b strongly expressed in retinal ganglion cells (RGCs), and knockdown of Sox11b inhibited RGC axon regrowth in retinal explants.
Title: Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration.

Sox11a/b knockdown in zebrafish causes brain abnormalities, potentially explaining the brain phenotype of Coffin-Siris syndrome in humans.
Title: De novo SOX11 mutations cause Coffin-Siris syndrome.

Results find that Sox11b function is essential for developmental angiogenesis in zebrafish embryos, specifically regulating sprouting angiogenesis.
Title: Mutant-specific gene expression profiling identifies SRY-related HMG box 11b (SOX11b) as a novel regulator of vascular development in zebrafish.

Sox11b promotes neuronal determination of endogenous stem cells and regenerative neurogenesis following spinal cord injury in the adult zebrafish.
Title: Transcription factor Sox11b is involved in spinal cord regeneration in adult zebrafish.

the duplicated zebrafish sox11a and -b loci were used to test the duplication, degeneration, complementation model of genome evolution through whole genome duplication.
Title: Regulatory divergence of the duplicated chromosomal loci sox11a/b by subpartitioning and sequence evolution of enhancers in zebrafish.

The following sox11b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sox11b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03795	NM_131337.1 Latest version!	Danio rerio SRY-box transcription factor 11b (sox11b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sox11b ( NM_131337.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571412.1 Danio rerio SRY-box transcription factor 11b (sox11b), mRNA.

Price & Availability↑

CloneID	ODa03795
Clone ID Related Accession (Same CDS sequence)	NM_131337.1
Accession Version	NM_131337.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-30
Organism	Danio rerio(zebrafish)
Product	SRY-box transcription factor 11b
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ237813.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ237813.1 [ECO:0000332] ##Evidence-Data-END##

ATGGTGCAGC AGACGGAGCA CAGCGAGACG GAGAGCAGCG TGTCGCGAGA GACCACAGAC 
ACCGAGGAGA GCGAAATGAT GGCTTGCAGC CCGGTGCCAC CGAAACCGGA CTGGTGCAAG 
ACAGCCACCG GCCACATCAA ACGACCCATG AATGCGTTTA TGGTATGGTC CAAAATCGAG 
AGGAGAAAAA TCATGGAGCA GTCTCCAGAC ATGCACAACG CAGAGATCTC CAAAAGGCTG 
GGGAAGCGGT GGAAAATGCT GAAGGACAGC GAAAAGATTC CCTTTATCCG CGAAGCCGAG 
CGGCTCCGGC TCCAACACAT GGCTGACTAC CCCGACTACA AATACAGACC CAAGAAAAAA 
CCAAAGCTCG ACAGCTCCTC AAAACCAGCA GTGCAGTCGC CGGAGAAGAT TAGCAAAAGT 
GTCAAAGCAG CCGCAGGGAA GAAGTGCGCC AAACTCAAGC CCAGCAAACC GGGGAACATT 
ACCGCCAGAG CATCCACACA AGACTGCAGA TTCAACTATG TTTTCACAAA CTTAAAAGTG 
ACCAAGTCTA TCAAAAGGGA ACTTACTGAC GACGAAGACG ACGACGACGA TGATGATGAC 
GACGACGACG AGGAGGATGA CTACGAGGAC GAGGAGCACA TCAGGCTGCA CAACGTCCCC 
GCGAGCCCCA CGCTGAGCTC CGCTGCGGAG TCCGAGCATG GCGCGAGCAT GTACGAGGAG 
TCCCGGCACA CGAGCGCGAC TCCCGGCAGC AGACTGTTTT ACAACTTCAA GAACATTACC 
AAGCAGAGCG CAGCTTACCC TGCCTCGGTG TCACCAGCAT CTTCTTTCAG GTCAGTCTCC 
TCTTCGTCCA GCAGCTCCAG CGAGGACTCC GACGACTTGC TGGTGGACTT CAGTTTGAAC 
TTAGCGGCGG GCTCTCACAC CGCGGATTTG GGGAACACTT CAGGAAACCT TTGCCTCTCT 
CTGGTGGATA AAGATTTGGA CTCGTTCAGC GAGGGCAGCC TCGGTTCTCA CTTCGAGTTC 
CCGGACTATT GCACTCCTGA GCTCAGTGAG ATGATCGCGG GAGACTGGCT GGAGGCGAAC 
TTTTCAGACC TGGTTTTCAC TTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571412.1
CDS	25..1131
Translation	MVQQTEHSETESSVSRETTDTEESEMMACSPVPPKPDWCKTATGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLQHMADYPDYKYRPKKKPKLDSSSKPAVQSPEKISKSVKAAAGKKCAKLKPSKPGNITARASTQDCRFNYVFTNLKVTKSIKRELTDDEDDDDDDDDDDDEEDDYEDEEHIRLHNVPASPTLSSAAESEHGASMYEESRHTSATPGSRLFYNFKNITKQSAAYPASVSPASSFRSVSSSSSSSSEDSDDLLVDFSLNLAAGSHTADLGNTSGNLCLSLVDKDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWLEANFSDLVFTY

Target ORF information:

RefSeq Version	NM_131337.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio SRY-box transcription factor 11b (sox11b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131337.1

ORF Insert Sequence:

ATGGTGCAGC AGACGGAGCA CAGCGAGACG GAGAGCAGCG TGTCGCGAGA GACCACAGAC 
ACCGAGGAGA GCGAAATGAT GGCTTGCAGC CCGGTGCCAC CGAAACCGGA CTGGTGCAAG 
ACAGCCACCG GCCACATCAA ACGACCCATG AATGCGTTTA TGGTATGGTC CAAAATCGAG 
AGGAGAAAAA TCATGGAGCA GTCTCCAGAC ATGCACAACG CAGAGATCTC CAAAAGGCTG 
GGGAAGCGGT GGAAAATGCT GAAGGACAGC GAAAAGATTC CCTTTATCCG CGAAGCCGAG 
CGGCTCCGGC TCCAACACAT GGCTGACTAC CCCGACTACA AATACAGACC CAAGAAAAAA 
CCAAAGCTCG ACAGCTCCTC AAAACCAGCA GTGCAGTCGC CGGAGAAGAT TAGCAAAAGT 
GTCAAAGCAG CCGCAGGGAA GAAGTGCGCC AAACTCAAGC CCAGCAAACC GGGGAACATT 
ACCGCCAGAG CATCCACACA AGACTGCAGA TTCAACTATG TTTTCACAAA CTTAAAAGTG 
ACCAAGTCTA TCAAAAGGGA ACTTACTGAC GACGAAGACG ACGACGACGA TGATGATGAC 
GACGACGACG AGGAGGATGA CTACGAGGAC GAGGAGCACA TCAGGCTGCA CAACGTCCCC 
GCGAGCCCCA CGCTGAGCTC CGCTGCGGAG TCCGAGCATG GCGCGAGCAT GTACGAGGAG 
TCCCGGCACA CGAGCGCGAC TCCCGGCAGC AGACTGTTTT ACAACTTCAA GAACATTACC 
AAGCAGAGCG CAGCTTACCC TGCCTCGGTG TCACCAGCAT CTTCTTTCAG GTCAGTCTCC 
TCTTCGTCCA GCAGCTCCAG CGAGGACTCC GACGACTTGC TGGTGGACTT CAGTTTGAAC 
TTAGCGGCGG GCTCTCACAC CGCGGATTTG GGGAACACTT CAGGAAACCT TTGCCTCTCT 
CTGGTGGATA AAGATTTGGA CTCGTTCAGC GAGGGCAGCC TCGGTTCTCA CTTCGAGTTC 
CCGGACTATT GCACTCCTGA GCTCAGTGAG ATGATCGCGG GAGACTGGCT GGAGGCGAAC 
TTTTCAGACC TGGTTTTCAC TTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Histological and transcriptomic effects of 17?-methyltestosterone on zebrafish gonad development.
BMC genomics18(1)557(2017 Jul)
Lee SLJ,Horsfield JA,Black MA,Rutherford K,Fisher A,Gemmell NJ

Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration.
Neuroscience bulletin33(1)53-61(2017 Feb)
Mu Z,Zhang S,He C,Hou H,Liu D,Hu N,Xu H

The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation.
Nature genetics47(6)625-31(2015 Jun)
Wang Y,Lu Y,Zhang Y,Ning Z,Li Y,Zhao Q,Lu H,Huang R,Xia X,Feng Q,Liang X,Liu K,Zhang L,Lu T,Huang T,Fan D,Weng Q,Zhu C,Lu Y,Li W,Wen Z,Zhou C,Tian Q,Kang X,Shi M,Zhang W,Jang S,Du F,He S,Liao L,Li Y,Gui B,He H,Ning Z,Yang C,He L,Luo L,Yang R,Luo Q,Liu X,Li S,Huang W,Xiao L,Lin H,Han B,Zhu Z

Sox4 regulates choroid fissure closure by limiting Hedgehog signaling during ocular morphogenesis.
Developmental biology399(1)139-53(2015 Mar)
Wen W,Pillai-Kastoori L,Wilson SG,Morris AC

Sequencing and De Novo Assembly of the Gonadal Transcriptome of the Endangered Chinese Sturgeon (Acipenser sinensis).
PloS one10(6)e0127332(2015)
Yue H,Li C,Du H,Zhang S,Wei Q

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sox11b cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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