Gene Symbol | mec-4 |
Entrez Gene ID | 181728 |
Full Name | Degenerin mec-4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » mec-4 cDNA ORF clone
Gene Symbol | mec-4 |
Entrez Gene ID | 181728 |
Full Name | Degenerin mec-4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_078311.7 | NP_510712.2 | Degenerin mec-4 |
NM_078311.5 | NP_510712.2 | Degenerin mec-4 |
SCNN1G | XP_001093466.1 | |
Mus musculus (house mouse) | Scnn1g | NP_035456.1 |
Caenorhabditis elegans (roundworm) | asic-1 | NP_491214.3 |
Caenorhabditis elegans (roundworm) | mec-4 | NP_510712.2 |
Caenorhabditis elegans (roundworm) | del-1 | NP_510380.1 |
Caenorhabditis elegans (roundworm) | unc-8 | NP_501138.1 |
Xenopus tropicalis (tropical clawed frog) | scnn1g | XP_004918046.1 |
Pan troglodytes (chimpanzee) | SCNN1G | XP_003315070.1 |
Caenorhabditis elegans (roundworm) | unc-105 | NP_001254142.1 |
Caenorhabditis elegans (roundworm) | asic-2 | NP_492099.1 |
Caenorhabditis elegans (roundworm) | mec-10 | NP_509438.1 |
Bos taurus (cattle) | SCNN1G | NP_001180103.1 |
Gallus gallus (chicken) | SCNN1G | XP_414880.2 |
Homo sapiens (human) | SCNN1G | NP_001030.2 |
Rattus norvegicus (Norway rat) | Scnn1g | NP_058742.1 |
Canis lupus familiaris (dog) | SCNN1G | XP_547093.2 |
Caenorhabditis elegans (roundworm) | deg-1 | NP_509311.1 |
Caenorhabditis elegans (roundworm) | del-4 | NP_492230.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
MEC-6 and POML-1 interact with MEC-4 to facilitate expression and localization of MEC-4 on the cell surface. Thus MEC-6 and POML-1 act more like chaperones for MEC-4 than channel components.
Title: Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins.
MEC-10, but not MEC-6, forms puncta in touch receptor neurites that colocalize with MEC-4 when MEC-4 is overexpressed in the touch receptor neurons
Title: Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.
Ubiquitination of MEC-4 reduces the amount of MEC-4 protein in the processes of ALM neurons and, consequently, the mechanoreceptor current.
Title: Regulation of mechanosensation in C. elegans through ubiquitination of the MEC-4 mechanotransduction channel.
MEC-4 is distributed essentially evenly with MEC-2 around the circumference of touch receptor neurites that serve as gating tethers critical for channel activation by mechano-electrical transduction.
Title: Nanoscale organization of the MEC-4 DEG/ENaC sensory mechanotransduction channel in Caenorhabditis elegans touch receptor neurons.
MEC-4/MEC-10 DEG/ENaC or its partners MEC-6, MEC-7, and MEC-9 blocked DAF-16::GFP nuclear accumulation induced by hypergravity but did not affect DAF-16 response to other stresses
Title: Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF-16/FoxO activity in Caenorhabditis elegans.
The following mec-4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mec-4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349687 | |
Clone ID Related Accession (Same CDS sequence) | NM_078311.7 , NM_078311.5 | |
Accession Version | NM_078311.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Degenerin mec-4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_078311.6. |
1 | ATGTCATGGA TGCAAAACCT GAAAAACTAC CAACACCTTC GGGACCCATC CGAGTACATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_510712.2 |
CDS | 2..2308 |
Translation |
Target ORF information:
Target ORF information:
|
NM_078311.7 |
1 | ATGTCATGGA TGCAAAACCT GAAAAACTAC CAACACCTTC GGGACCCATC CGAGTACATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349687 | |
Clone ID Related Accession (Same CDS sequence) | NM_078311.7 , NM_078311.5 | |
Accession Version | NM_078311.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Degenerin mec-4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_078311.4. COMPLETENESS: incomplete on both ends. |
1 | ATGTCATGGA TGCAAAACCT GAAAAACTAC CAACACCTTC GGGACCCATC CGAGTACATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_510712.2 |
CDS | 1..2307 |
Translation |
Target ORF information:
Target ORF information:
|
NM_078311.5 |
1 | ATGTCATGGA TGCAAAACCT GAAAAACTAC CAACACCTTC GGGACCCATC CGAGTACATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |