ric-3 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	ric-3
Entrez Gene ID	177570
Full Name	Resistance to inhibitors of cholinesterase protein 3
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_068898.4	NP_501299.1	Resistance to inhibitors of cholinesterase protein 3
NM_068898.5	NP_501299.1	Resistance to inhibitors of cholinesterase protein 3

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RIC-3 phosphorylation at Ser-164 depends on opposing functions of the phosphatase calcineurin (TAX-6), and of the casein kinase II homologue KIN-10. RIC-3 phosphorylation enables effects of this chaperone on GABAA receptors in addition to nAChRs.
Title: RIC-3 phosphorylation enables dual regulation of excitation and inhibition of Caenorhabditis elegans muscle.

The conserved residues in the second RIC-3 transmembrane domain are needed for its interactions with DEG-3,DES-2 and ACR-16.
Title: Receptor and subunit specific interactions of RIC-3 with nicotinic acetylcholine receptors.

Loss of BATH-42 function leads to increased RIC-3 expression and decreased activity of nicotinic acetylcholine receptors in Caenorhabditis elegans vulva muscles.
Title: The BTB-MATH protein BATH-42 interacts with RIC-3 to regulate maturation of nicotinic acetylcholine receptors.

RIC-3 alternative splicing enables subtype specific regulation of nicotinic acetylcholine receptor maturation.
Title: The conserved RIC-3 coiled-coil domain mediates receptor-specific interactions with nicotinic acetylcholine receptors.

subunit-specific interactions of RIC-3 with nAChR subunits DEG-3/DES-2, mediated by the transmembrane domains, are sufficient for the effects of RIC-3 on nAChR quantity and quality
Title: RIC-3 affects properties and quantity of nicotinic acetylcholine receptors via a mechanism that does not require the coiled-coil domains.

The following ric-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ric-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa343408	NM_068898.5 Latest version!	Caenorhabditis elegans Resistance to inhibitors of cholinesterase protein 3 (ric-3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OCa343408	NM_068898.4	Caenorhabditis elegans Resistance to inhibitors of cholinesterase protein 3 (ric-3), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ric-3 ( NM_068898.4 ) cDNA ORF clone, Caenorhabditis elegans -> NP_501299.1 Caenorhabditis elegans Resistance to inhibitors of cholinesterase protein 3 (ric-3), partial mRNA.

Price & Availability↑

CloneID	OCa343408
Clone ID Related Accession (Same CDS sequence)	NM_068898.4 , NM_068898.5
Accession Version	NM_068898.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	Resistance to inhibitors of cholinesterase protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_068898.3. COMPLETENESS: incomplete on both ends.

ATGCCAAAAA CTGAACGGCG TCGTGATAGA GATCGAGACA GAGATCGAGA AAGGAGAAAC 
AGACGAAAAA GGGATGATAG TTACGATGAT TACGATGAAG AAGGTGGAAT ATCAGGATGG 
AAGCTTGGTT TAGTATTTGG AGTAATCGTT GTTTGCTTTG CAATGCTTTA TCCAACACTT 
TTCCATCCAA TGCTAATGGG ATTCTTGGGT CGTTCACCAC CATCAAGTCC ATCAATAAAC 
CAACAACGTC CACCAATTCA TCCAGCAATG GGTGGGGGAA GTGGACAACG TCATCCAGGT 
GGTGGTGCAG ATGTACATCC AGCAATGAGA ATGGCTCAAG CACAAGCTGA AAGTCAATCT 
GGTGGATCAA AGGGAATGTT CACATGGATG TTACCTGTAT ATACAATCGG AGTTGTTTTA 
TTTCTTTTGT ATACGCTGTT TAAATCAAAA GGAAAGAAAT CAAAGCGAAA GAAGAGAAAT 
TATTTTGATT CTGAAGACGA TGATGATGAA TCTGAAAGTG AGACTAAATA TGGCGGAAAA 
TTTGGTAAAA AGAAGCTTGA AGGACTTCAG AAAAGGCTTC GAGAGACTGA AAGTGCAATG 
TCTAAGATTT TAGAACAACT TGAATCAGTA CAAGCTGGCG CTAATCCTGT CGACTTAGAT 
GCTGCCGATA AGAGGTCGGA ACAACTTGAA GAAGATCCAT CAGTTAAAGA AGCAGTTGGA 
TTAACTGAAA CCAATGAACA ATACATAAAA GATCTTGAGG TTGCACTGAA AGAGTTTCAG 
TCCTTGTCAA AAGAATATGA TAAAGCGAAA ATGAAGAAAC TGAAAAGAAA AGATTCTTCG 
AGTGACGAAG ATGAAGAAGA CGAAGAAGAG AATAGCTCTG AATTGTCAGA AATCGAAGAG 
GAAGAAGAGG AAGTTAAACC AGTGAAAAAG TCAAAATCAT CCTCCCAATC AGTTGGAAAA 
AGGAAGAATC GACCAAAAAG CACATCAGAA GAAGAAGATG AAGGAGAAGA AGAATCACGA 
AAAGTTGCAG AAGATGCTGA AGAAGAAGGA ATTGACATTG ATTCTGAGAT CCGAGAGCAC 
GCGGAAAAGG AGAAAAAAGA TAAAAATGTG CGAAGGCGGA GACCTAAAAA GACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_501299.1
CDS	1..1137
Translation	MPKTERRRDRDRDRDRERRNRRKRDDSYDDYDEEGGISGWKLGLVFGVIVVCFAMLYPTLFHPMLMGFLGRSPPSSPSINQQRPPIHPAMGGGSGQRHPGGGADVHPAMRMAQAQAESQSGGSKGMFTWMLPVYTIGVVLFLLYTLFKSKGKKSKRKKRNYFDSEDDDDESESETKYGGKFGKKKLEGLQKRLRETESAMSKILEQLESVQAGANPVDLDAADKRSEQLEEDPSVKEAVGLTETNEQYIKDLEVALKEFQSLSKEYDKAKMKKLKRKDSSSDEDEEDEEENSSELSEIEEEEEEVKPVKKSKSSSQSVGKRKNRPKSTSEEEDEGEEESRKVAEDAEEEGIDIDSEIREHAEKEKKDKNVRRRRPKKT

Target ORF information:

RefSeq Version	NM_068898.4
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Resistance to inhibitors of cholinesterase protein 3 (ric-3), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_068898.4

ORF Insert Sequence:

ATGCCAAAAA CTGAACGGCG TCGTGATAGA GATCGAGACA GAGATCGAGA AAGGAGAAAC 
AGACGAAAAA GGGATGATAG TTACGATGAT TACGATGAAG AAGGTGGAAT ATCAGGATGG 
AAGCTTGGTT TAGTATTTGG AGTAATCGTT GTTTGCTTTG CAATGCTTTA TCCAACACTT 
TTCCATCCAA TGCTAATGGG ATTCTTGGGT CGTTCACCAC CATCAAGTCC ATCAATAAAC 
CAACAACGTC CACCAATTCA TCCAGCAATG GGTGGGGGAA GTGGACAACG TCATCCAGGT 
GGTGGTGCAG ATGTACATCC AGCAATGAGA ATGGCTCAAG CACAAGCTGA AAGTCAATCT 
GGTGGATCAA AGGGAATGTT CACATGGATG TTACCTGTAT ATACAATCGG AGTTGTTTTA 
TTTCTTTTGT ATACGCTGTT TAAATCAAAA GGAAAGAAAT CAAAGCGAAA GAAGAGAAAT 
TATTTTGATT CTGAAGACGA TGATGATGAA TCTGAAAGTG AGACTAAATA TGGCGGAAAA 
TTTGGTAAAA AGAAGCTTGA AGGACTTCAG AAAAGGCTTC GAGAGACTGA AAGTGCAATG 
TCTAAGATTT TAGAACAACT TGAATCAGTA CAAGCTGGCG CTAATCCTGT CGACTTAGAT 
GCTGCCGATA AGAGGTCGGA ACAACTTGAA GAAGATCCAT CAGTTAAAGA AGCAGTTGGA 
TTAACTGAAA CCAATGAACA ATACATAAAA GATCTTGAGG TTGCACTGAA AGAGTTTCAG 
TCCTTGTCAA AAGAATATGA TAAAGCGAAA ATGAAGAAAC TGAAAAGAAA AGATTCTTCG 
AGTGACGAAG ATGAAGAAGA CGAAGAAGAG AATAGCTCTG AATTGTCAGA AATCGAAGAG 
GAAGAAGAGG AAGTTAAACC AGTGAAAAAG TCAAAATCAT CCTCCCAATC AGTTGGAAAA 
AGGAAGAATC GACCAAAAAG CACATCAGAA GAAGAAGATG AAGGAGAAGA AGAATCACGA 
AAAGTTGCAG AAGATGCTGA AGAAGAAGGA ATTGACATTG ATTCTGAGAT CCGAGAGCAC 
GCGGAAAAGG AGAAAAAAGA TAAAAATGTG CGAAGGCGGA GACCTAAAAA GACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ric-3 ( NM_068898.5 ) cDNA ORF clone, Caenorhabditis elegans -> NP_501299.1 Caenorhabditis elegans Resistance to inhibitors of cholinesterase protein 3 (ric-3), mRNA.

Price & Availability↑

CloneID	OCa343408
Clone ID Related Accession (Same CDS sequence)	NM_068898.4 , NM_068898.5
Accession Version	NM_068898.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	Resistance to inhibitors of cholinesterase protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_068898.4.

ATGCCAAAAA CTGAACGGCG TCGTGATAGA GATCGAGACA GAGATCGAGA AAGGAGAAAC 
AGACGAAAAA GGGATGATAG TTACGATGAT TACGATGAAG AAGGTGGAAT ATCAGGATGG 
AAGCTTGGTT TAGTATTTGG AGTAATCGTT GTTTGCTTTG CAATGCTTTA TCCAACACTT 
TTCCATCCAA TGCTAATGGG ATTCTTGGGT CGTTCACCAC CATCAAGTCC ATCAATAAAC 
CAACAACGTC CACCAATTCA TCCAGCAATG GGTGGGGGAA GTGGACAACG TCATCCAGGT 
GGTGGTGCAG ATGTACATCC AGCAATGAGA ATGGCTCAAG CACAAGCTGA AAGTCAATCT 
GGTGGATCAA AGGGAATGTT CACATGGATG TTACCTGTAT ATACAATCGG AGTTGTTTTA 
TTTCTTTTGT ATACGCTGTT TAAATCAAAA GGAAAGAAAT CAAAGCGAAA GAAGAGAAAT 
TATTTTGATT CTGAAGACGA TGATGATGAA TCTGAAAGTG AGACTAAATA TGGCGGAAAA 
TTTGGTAAAA AGAAGCTTGA AGGACTTCAG AAAAGGCTTC GAGAGACTGA AAGTGCAATG 
TCTAAGATTT TAGAACAACT TGAATCAGTA CAAGCTGGCG CTAATCCTGT CGACTTAGAT 
GCTGCCGATA AGAGGTCGGA ACAACTTGAA GAAGATCCAT CAGTTAAAGA AGCAGTTGGA 
TTAACTGAAA CCAATGAACA ATACATAAAA GATCTTGAGG TTGCACTGAA AGAGTTTCAG 
TCCTTGTCAA AAGAATATGA TAAAGCGAAA ATGAAGAAAC TGAAAAGAAA AGATTCTTCG 
AGTGACGAAG ATGAAGAAGA CGAAGAAGAG AATAGCTCTG AATTGTCAGA AATCGAAGAG 
GAAGAAGAGG AAGTTAAACC AGTGAAAAAG TCAAAATCAT CCTCCCAATC AGTTGGAAAA 
AGGAAGAATC GACCAAAAAG CACATCAGAA GAAGAAGATG AAGGAGAAGA AGAATCACGA 
AAAGTTGCAG AAGATGCTGA AGAAGAAGGA ATTGACATTG ATTCTGAGAT CCGAGAGCAC 
GCGGAAAAGG AGAAAAAAGA TAAAAATGTG CGAAGGCGGA GACCTAAAAA GACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_501299.1
CDS	13..1149
Translation	MPKTERRRDRDRDRDRERRNRRKRDDSYDDYDEEGGISGWKLGLVFGVIVVCFAMLYPTLFHPMLMGFLGRSPPSSPSINQQRPPIHPAMGGGSGQRHPGGGADVHPAMRMAQAQAESQSGGSKGMFTWMLPVYTIGVVLFLLYTLFKSKGKKSKRKKRNYFDSEDDDDESESETKYGGKFGKKKLEGLQKRLRETESAMSKILEQLESVQAGANPVDLDAADKRSEQLEEDPSVKEAVGLTETNEQYIKDLEVALKEFQSLSKEYDKAKMKKLKRKDSSSDEDEEDEEENSSELSEIEEEEEEVKPVKKSKSSSQSVGKRKNRPKSTSEEEDEGEEESRKVAEDAEEEGIDIDSEIREHAEKEKKDKNVRRRRPKKT

Target ORF information:

RefSeq Version	NM_068898.5
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Resistance to inhibitors of cholinesterase protein 3 (ric-3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_068898.5

ORF Insert Sequence:

ATGCCAAAAA CTGAACGGCG TCGTGATAGA GATCGAGACA GAGATCGAGA AAGGAGAAAC 
AGACGAAAAA GGGATGATAG TTACGATGAT TACGATGAAG AAGGTGGAAT ATCAGGATGG 
AAGCTTGGTT TAGTATTTGG AGTAATCGTT GTTTGCTTTG CAATGCTTTA TCCAACACTT 
TTCCATCCAA TGCTAATGGG ATTCTTGGGT CGTTCACCAC CATCAAGTCC ATCAATAAAC 
CAACAACGTC CACCAATTCA TCCAGCAATG GGTGGGGGAA GTGGACAACG TCATCCAGGT 
GGTGGTGCAG ATGTACATCC AGCAATGAGA ATGGCTCAAG CACAAGCTGA AAGTCAATCT 
GGTGGATCAA AGGGAATGTT CACATGGATG TTACCTGTAT ATACAATCGG AGTTGTTTTA 
TTTCTTTTGT ATACGCTGTT TAAATCAAAA GGAAAGAAAT CAAAGCGAAA GAAGAGAAAT 
TATTTTGATT CTGAAGACGA TGATGATGAA TCTGAAAGTG AGACTAAATA TGGCGGAAAA 
TTTGGTAAAA AGAAGCTTGA AGGACTTCAG AAAAGGCTTC GAGAGACTGA AAGTGCAATG 
TCTAAGATTT TAGAACAACT TGAATCAGTA CAAGCTGGCG CTAATCCTGT CGACTTAGAT 
GCTGCCGATA AGAGGTCGGA ACAACTTGAA GAAGATCCAT CAGTTAAAGA AGCAGTTGGA 
TTAACTGAAA CCAATGAACA ATACATAAAA GATCTTGAGG TTGCACTGAA AGAGTTTCAG 
TCCTTGTCAA AAGAATATGA TAAAGCGAAA ATGAAGAAAC TGAAAAGAAA AGATTCTTCG 
AGTGACGAAG ATGAAGAAGA CGAAGAAGAG AATAGCTCTG AATTGTCAGA AATCGAAGAG 
GAAGAAGAGG AAGTTAAACC AGTGAAAAAG TCAAAATCAT CCTCCCAATC AGTTGGAAAA 
AGGAAGAATC GACCAAAAAG CACATCAGAA GAAGAAGATG AAGGAGAAGA AGAATCACGA 
AAAGTTGCAG AAGATGCTGA AGAAGAAGGA ATTGACATTG ATTCTGAGAT CCGAGAGCAC 
GCGGAAAAGG AGAAAAAAGA TAAAAATGTG CGAAGGCGGA GACCTAAAAA GACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

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ric-3 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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