Gene Symbol | exo-3 |
Entrez Gene ID | 173069 |
Full Name | DNA-(apurinic or apyrimidinic site) lyase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » exo-3 cDNA ORF clone
Gene Symbol | exo-3 |
Entrez Gene ID | 173069 |
Full Name | DNA-(apurinic or apyrimidinic site) lyase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001026413.3 | NP_001021584.1 | DNA-(apurinic or apyrimidinic site) lyase |
NM_001026414.3 | NP_001021585.1 | DNA-(apurinic or apyrimidinic site) lyase |
NM_001026413.4 | NP_001021584.1 | DNA-(apurinic or apyrimidinic site) lyase |
NM_001026414.4 | NP_001021585.1 | DNA-(apurinic or apyrimidinic site) lyase |
Drosophila melanogaster (fruit fly) | Rrp1 | NP_476841.1 |
Caenorhabditis elegans (roundworm) | exo-3 | NP_001021584.1 |
Oryza sativa (rice) | Os01g0801100 | NP_001044538.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This study demonstrated differential roles of EXO-3 in somatic cells and germ cells.
Title: Caenorhabditis elegans EXO-3 contributes to longevity and reproduction: differential roles in somatic cells and germ cells.
Base excision repair endonucleases APN-1 and EXO-3 function in the same pathway as DNA mismatch repair, to elicit DNA-directed toxicity in response to 5-fluorouracil.
Title: Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy.
Glu68 may play a role in coordinating Mg2+ binding for the enzyme catalytic mechanism.
Title: Characterization of Caenorhabditis elegans exonuclease-3 and evidence that a Mg2+-dependent variant exhibits a distinct mode of action on damaged DNA.
Exo-3 expresses apurinic/apyrimidinic endonuclease in a Saccharomyces cerevisiae mutant.
Title: Identification of two apurinic/apyrimidinic endonucleases from Caenorhabditis elegans by cross-species complementation.
The following exo-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the exo-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335728 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026413.3 , NM_001026413.4 | |
Accession Version | NM_001026413.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DNA-(apurinic or apyrimidinic site) lyase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_001026413.2. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021584.1 |
CDS | 1..867 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026413.3 |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335728 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026413.3 , NM_001026413.4 | |
Accession Version | NM_001026413.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | DNA-(apurinic or apyrimidinic site) lyase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001026413.3. |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021584.1 |
CDS | 46..912 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026413.4 |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337240 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026414.3 , NM_001026414.4 | |
Accession Version | NM_001026414.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DNA-(apurinic or apyrimidinic site) lyase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_001026414.2. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021585.1 |
CDS | 1..561 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026414.3 |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337240 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026414.3 , NM_001026414.4 | |
Accession Version | NM_001026414.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | DNA-(apurinic or apyrimidinic site) lyase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001026414.3. |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021585.1 |
CDS | 46..606 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026414.4 |
1 | ATGTCGAAGC GAAAAGCAGA AGAAGCACCA GCACCAAAGC TCGCCTCGAT CTTCACAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |